Acute Glomerulonephritis

Benzer, Meryem; Tülpar, Sebahat

doi:https://dx.doi.org/10.5222/j.child.2016.001

Review

DOI :10.5222/j.child.2016.001 IUP :10.5222/j.child.2016.001 Full Text (PDF)

Acute Glomerulonephritis

Acute glomerulonephritis (AGN) is a clinical syndrome which is associated with an acutely coırsing glomerular inflammation. The typical triad of its presenting symptoms is macroscopic hematuria, hypertension and edema. In children, the most common cause of AGN is poststreptococcal glomerulonefritis. The evidence (/if any) of previously experienced streptoccal infection, and serum complement level provide guidance for the differential diagnosis of AGN. In cases with typical APSGN there is no indication of kidney biopsy. The primary medical care of all patients is supportive, regardless of the etiology of AGN. Short termand long-term outcomes are generally favorable in children with APSGN Many clinical trials are currently proceeding for the development of both effective and safe vaccines against streptococcal infections.

Keywords: Acute glomerulonephritis, streptococcal infection, hematuria, ASO

DOI :10.5222/j.child.2016.001 IUP :10.5222/j.child.2016.001 Full Text (PDF)

Akut Gomerülonefritler

Meryem Benzer, Sebahat Tülpar

Akut glomerülonefrit (AGN), glomerüllerdeki akut seyirli bir inflamasyonun oluşturduğu bir klinik sendromdur. Tipik başvuru bulguları, makroskopik hematüri, hipertansiyon ve ödem üçlüsünden oluşur. Çocuklarda AGN’nin en sık nedeni poststreptokoksik glomerülonefrittir. Geçirilmiş bir streptokok enfeksiyonu kanıtı olup olmadığı ve serum kompleman seviyesi AGN ayırıcı tanısında yol göstericidir. Tipik APSGN vakalarında böbrek biyopsisi endikasyonu yoktur. AGN etiyolojisine bakılmaksızın tüm hastalara öncelikle destek tedavisi uygulanır. Çocuklarda APSGN’nin kısa ve uzun dönem prognozu genellikle iyidir. Streptokok enfeksiyonlarına karşı etkin ve güvenli aşıların geliştirilmesi için çok sayıda klinik çalışma hâlen yürütülmektedir.

Keywords: Akut glomerülonefrit, streptokok enfeksiyonu, hematüri, ASO

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APA

Benzer, M., & Tülpar, S. (2016). Acute Glomerulonephritis. Journal of Child, 16(1), 1-10. https://doi.org/10.5222/j.child.2016.001

AMA

Benzer M, Tülpar S. Acute Glomerulonephritis. Journal of Child. 2016;16(1):1-10. https://doi.org/10.5222/j.child.2016.001

ABNT

Benzer, M.; Tülpar, S. Acute Glomerulonephritis. Journal of Child, [Publisher Location], v. 16, n. 1, p. 1-10, 2016.

Chicago: Author-Date Style

Benzer, Meryem, and Sebahat Tülpar. 2016. “Acute Glomerulonephritis.” Journal of Child 16, no. 1: 1-10. https://doi.org/10.5222/j.child.2016.001

Chicago: Humanities Style

Benzer, Meryem, and Sebahat Tülpar. “Acute Glomerulonephritis.” Journal of Child 16, no. 1 (Jun. 2025): 1-10. https://doi.org/10.5222/j.child.2016.001

Harvard: Australian Style

Benzer, M & Tülpar, S 2016, 'Acute Glomerulonephritis', Journal of Child, vol. 16, no. 1, pp. 1-10, viewed 3 Jun. 2025, https://doi.org/10.5222/j.child.2016.001

Harvard: Author-Date Style

Benzer, M. and Tülpar, S. (2016) ‘Acute Glomerulonephritis’, Journal of Child, 16(1), pp. 1-10. https://doi.org/10.5222/j.child.2016.001 (3 Jun. 2025).

MLA

Benzer, Meryem, and Sebahat Tülpar. “Acute Glomerulonephritis.” Journal of Child, vol. 16, no. 1, 2016, pp. 1-10. [Database Container], https://doi.org/10.5222/j.child.2016.001

Vancouver

Benzer M, Tülpar S. Acute Glomerulonephritis. Journal of Child [Internet]. 3 Jun. 2025 [cited 3 Jun. 2025];16(1):1-10. Available from: https://doi.org/10.5222/j.child.2016.001 doi: 10.5222/j.child.2016.001

ISNAD

Benzer, Meryem - Tülpar, Sebahat. “Acute Glomerulonephritis”. Journal of Child 16/1 (Jun. 2025): 1-10. https://doi.org/10.5222/j.child.2016.001

Volume 16, Issue 12016, P. 1-10

TIMELINE

Submitted	25.08.2016
Accepted	07.03.2017

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