Food Protein-Induced Enterocolitis Syndrome

Altınel Zeynep

doi:https://dx.doi.org/10.5222/j.child.2019.08760

Review

DOI :10.5222/j.child.2019.08760 IUP :10.5222/j.child.2019.08760 Full Text (PDF)

Food Protein-Induced Enterocolitis Syndrome

Food protein–induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE)- mediated food allergy. However, the exact pathophysiology of FPIES is not clearly understood, cell mediated mechanisms are considered to be responsible. FPIES is classified in two forms: acute and chronic. There are no diagnostic laboratory tests for FPIES but laboratory methods can be used for other diseases in the differential diagnosis. The diagnosis of FPIES is based on clinical responses to elimination of suspected diets with resolution of symptoms, oral food challenges with reappearance of symptoms following provocation test by providing the offending food. Acute FPIES can be confused with other frequently seen childhood diseases. In this review, the clinical findings, diagnosis, diseases included in the differential diagnosis, treatments and follow-up of FPIES are examined in the light of the latest publications and recommendations.

Keywords: Food protein–induced enterocolitis syndrome, non-IgE mediated food allergy, food allergy, FPIES

DOI :10.5222/j.child.2019.08760 IUP :10.5222/j.child.2019.08760 Full Text (PDF)

Besin Proteini İlişkili Enterokolit Sendromu

Zeynep Hızlı Demirkale, Zeynep Altınel

Besin proteini ilişkili enterokolit sendromu (BPİES), immunglobulin E (IgE) aracılı olmayan besin alerjisidir. BPİES’in patofizyolojisi henüz tam aydınlatılamamakla birlikte, patofizyolojisinde hücre aracılı mekanizmaların sorumlu olduğu düşünülmektedir. Akut ve kronik olmak üzere iki şekilde sınıflandırılır. Tanı koydurucu laboratuvar testleri yoktur fakat ayırıcı tanıya giren diğer hastalıklar için laboratuvar yöntemlerinden yararlanılabilir. Tanı şüpheli besin diyetten çıkarıldıktan sonra yakınmaların tamamen düzelmesi ve besin provokasyonla yine verildiğinde akut BPİES bulgularının oluşması ile konulur. Akut BPİES sık görülen diğer çocukluk çağı hastalıkları ile karıştırılabilir. Bu derlemede, BPİES’in klinik bulguları, tanısı, ayırıcı tanıya giren hastalıkları, tedavisi ve izlemi son yayınlar ve öneriler eşliğinde incelenmiştir

Keywords: Besin protein ilişkili enterokolit sendromu, IgE aracılı olmayan besin alerjisi, besin alerjisi, BPİES

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Hızlı Demirkale, Z., & Altınel, Z. (2019). Food Protein-Induced Enterocolitis Syndrome. Journal of Child, 19(1), 1-9. https://doi.org/10.5222/j.child.2019.08760

AMA

Hızlı Demirkale Z, Altınel Z. Food Protein-Induced Enterocolitis Syndrome. Journal of Child. 2019;19(1):1-9. https://doi.org/10.5222/j.child.2019.08760

ABNT

Hızlı Demirkale, Z.; Altınel, Z. Food Protein-Induced Enterocolitis Syndrome. Journal of Child, [Publisher Location], v. 19, n. 1, p. 1-9, 2019.

Chicago: Author-Date Style

Hızlı Demirkale, Zeynep, and Zeynep Altınel. 2019. “Food Protein-Induced Enterocolitis Syndrome.” Journal of Child 19, no. 1: 1-9. https://doi.org/10.5222/j.child.2019.08760

Chicago: Humanities Style

Hızlı Demirkale, Zeynep, and Zeynep Altınel. “Food Protein-Induced Enterocolitis Syndrome.” Journal of Child 19, no. 1 (May. 2024): 1-9. https://doi.org/10.5222/j.child.2019.08760

Harvard: Australian Style

Hızlı Demirkale, Z & Altınel, Z 2019, 'Food Protein-Induced Enterocolitis Syndrome', Journal of Child, vol. 19, no. 1, pp. 1-9, viewed 18 May. 2024, https://doi.org/10.5222/j.child.2019.08760

Harvard: Author-Date Style

Hızlı Demirkale, Z. and Altınel, Z. (2019) ‘Food Protein-Induced Enterocolitis Syndrome’, Journal of Child, 19(1), pp. 1-9. https://doi.org/10.5222/j.child.2019.08760 (18 May. 2024).

MLA

Hızlı Demirkale, Zeynep, and Zeynep Altınel. “Food Protein-Induced Enterocolitis Syndrome.” Journal of Child, vol. 19, no. 1, 2019, pp. 1-9. [Database Container], https://doi.org/10.5222/j.child.2019.08760

Vancouver

Hızlı Demirkale Z, Altınel Z. Food Protein-Induced Enterocolitis Syndrome. Journal of Child [Internet]. 18 May. 2024 [cited 18 May. 2024];19(1):1-9. Available from: https://doi.org/10.5222/j.child.2019.08760 doi: 10.5222/j.child.2019.08760

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Hızlı Demirkale, Zeynep - Altınel, Zeynep. “Food Protein-Induced Enterocolitis Syndrome”. Journal of Child 19/1 (May. 2024): 1-9. https://doi.org/10.5222/j.child.2019.08760

Volume 19, Issue 12019, P. 1-9

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30.04.2019

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Besin Proteini İlişkili Enterokolit Sendromu

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