Journal of Child

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Research Article


DOI :10.26650/jchild.2022.778441   IUP :10.26650/jchild.2022.778441    Full Text (PDF)

Single Center Experience of Periodic Fever Syndromes

Şerife Gül Karadağ, Hafize Emine Sönmez, Ayşe Tanatar, Nuray Aktay Ayaz

Objective: We aimed to evaluate the patients referred to the pediatric rheumatology outpatient clinic with suspected periodic fever syndromes. Method: Patients diagnosed with periodic fever syndrome in the pediatric rheumatology outpatient clinic between March 2018 and March 2019 were evaluated. Results: A total of 1561 patients were diagnosed with rheumatologic disease in a year-long period. Of these patients, 738 (47.3%) had recurrent fever syndromes. Of these, 591 patients had familial Mediterranean fever (FMF), 91 had periodic fever syndrome with aphthous stomatitis, pharyngitis and adenitis (PFAPA), 2 had mevalonate kinase (MVK) deficiency-hyperimmunoglobulin D syndrome (HIDS), 2 had cryopyrinassociated periodic fever syndrome (CAPS) and 1 patient was diagnosed with tumor necrosis factor (TNF) receptor-associated periodic fever syndrome (TRAPS). Fifty-one patients who did not comply with the classification criteria and did not carry any mutations in the genetic tests were diagnosed with undefined autoinflammatory disease. Conclusion: The diagnosis of periodic fever syndromes requires attentive evaluation. A detailed questioning of the symptoms and signs of the patient will prevent unnecessary referrals to pediatric rheumatology units and will decrease the expenses of healthcare.

Keywords: Familial Mediterranean fever, autoinflammatory disease, periodic fever syndromes
DOI :10.26650/jchild.2022.778441   IUP :10.26650/jchild.2022.778441    Full Text (PDF)

Tekrarlayan Ateş Sendromlarında Tek Merkez Deneyimi

Şerife Gül Karadağ, Hafize Emine Sönmez, Ayşe Tanatar, Nuray Aktay Ayaz

Amaç: Çocuk romatoloji polikliniğine tekrarlayan ateş sendromu şüphesi ile yönlendirilen hastaların değerlendirilmesi amaçlandı. Yöntem: Mart 2018-Mart 2019 tarihleri arasında çocuk romatoloji polikliniğinde tekrarlayan ateş sendromu tanısı alan hastalar değerlendirildi. Bulgular: Bir yıl süresince toplam 1561 hastaya romatolojik hastalık tanısı konuldu. Bu hastaların 738 (%47,3)’ini tekrarlayan ateş sendromları oluşturmaktaydı. Hastaların 591’i ailevi Akdeniz ateşi (AAA), 91’i aftöz stomatit, farenjit ve adenit ile giden periyodik ateş sendromu (PFAPA), 2’si mevalonat kinaz (MVK) eksikliği-hiperimmünoglobulin D sendromu (HİDS), 2’si kriyopirin ilişkili periyodik ateş sendromu (CAPS), 1’i tümör nekroz faktör (TNF) reseptörü ilişkili periyodik ateş sendromu (TRAPS) tanısı aldı. Sınıflandırma ölçütlerine uymayan ve genetik inceleme sonuçlarında mutasyon saptanmayan 51 hastaya ise sınıflandırılamayan otoinflamatuar hastalık-tekrarlayan ateş sendromu tanısı konuldu. Sonuç: Tekrarlayan ateş sendromlarının teşhisi dikkatli bir değerlendirme gerektirir. Hastanın belirti ve bulgularının detaylı bir şekilde sorgulanması çocuk romatoloji birimlerine gereksiz yönlendirmelerini önleyecek ve sağlık harcamalarını azaltacaktır.

Keywords: Ailevi Akdeniz ateşi, otoinflamatuar hastalık, tekrarlayan ateş sendromları

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References

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APA

Karadağ, Ş.G., Sönmez, H.E., Tanatar, A., & Aktay Ayaz, N. (2022). Single Center Experience of Periodic Fever Syndromes. Journal of Child, 22(1), 25-29. https://doi.org/10.26650/jchild.2022.778441


AMA

Karadağ Ş G, Sönmez H E, Tanatar A, Aktay Ayaz N. Single Center Experience of Periodic Fever Syndromes. Journal of Child. 2022;22(1):25-29. https://doi.org/10.26650/jchild.2022.778441


ABNT

Karadağ, Ş.G.; Sönmez, H.E.; Tanatar, A.; Aktay Ayaz, N. Single Center Experience of Periodic Fever Syndromes. Journal of Child, [Publisher Location], v. 22, n. 1, p. 25-29, 2022.


Chicago: Author-Date Style

Karadağ, Şerife Gül, and Hafize Emine Sönmez and Ayşe Tanatar and Nuray Aktay Ayaz. 2022. “Single Center Experience of Periodic Fever Syndromes.” Journal of Child 22, no. 1: 25-29. https://doi.org/10.26650/jchild.2022.778441


Chicago: Humanities Style

Karadağ, Şerife Gül, and Hafize Emine Sönmez and Ayşe Tanatar and Nuray Aktay Ayaz. “Single Center Experience of Periodic Fever Syndromes.” Journal of Child 22, no. 1 (Apr. 2024): 25-29. https://doi.org/10.26650/jchild.2022.778441


Harvard: Australian Style

Karadağ, ŞG & Sönmez, HE & Tanatar, A & Aktay Ayaz, N 2022, 'Single Center Experience of Periodic Fever Syndromes', Journal of Child, vol. 22, no. 1, pp. 25-29, viewed 25 Apr. 2024, https://doi.org/10.26650/jchild.2022.778441


Harvard: Author-Date Style

Karadağ, Ş.G. and Sönmez, H.E. and Tanatar, A. and Aktay Ayaz, N. (2022) ‘Single Center Experience of Periodic Fever Syndromes’, Journal of Child, 22(1), pp. 25-29. https://doi.org/10.26650/jchild.2022.778441 (25 Apr. 2024).


MLA

Karadağ, Şerife Gül, and Hafize Emine Sönmez and Ayşe Tanatar and Nuray Aktay Ayaz. “Single Center Experience of Periodic Fever Syndromes.” Journal of Child, vol. 22, no. 1, 2022, pp. 25-29. [Database Container], https://doi.org/10.26650/jchild.2022.778441


Vancouver

Karadağ ŞG, Sönmez HE, Tanatar A, Aktay Ayaz N. Single Center Experience of Periodic Fever Syndromes. Journal of Child [Internet]. 25 Apr. 2024 [cited 25 Apr. 2024];22(1):25-29. Available from: https://doi.org/10.26650/jchild.2022.778441 doi: 10.26650/jchild.2022.778441


ISNAD

Karadağ, ŞerifeGül - Sönmez, HafizeEmine - Tanatar, Ayşe - Aktay Ayaz, Nuray. “Single Center Experience of Periodic Fever Syndromes”. Journal of Child 22/1 (Apr. 2024): 25-29. https://doi.org/10.26650/jchild.2022.778441



TIMELINE


Submitted09.08.2020
Accepted13.07.2021
Published Online18.05.2022

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