Journal of Child

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DOI :10.26650/jchild.2020.3.809801   IUP :10.26650/jchild.2020.3.809801    Full Text (PDF)

Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia

Özgül Bulut, Meryem Hocaoğlu, Nurgül Bulut, Selin Demirer, Abdulkadir Turgut, Fahri Ovalı

Objective: To compare the maternal risk factors and early neonatal outcomes in early-onset and late-onset preeclampsia. Material and Methods: In our hospital, patients diagnosed with preeclampsia were evaluated retrospectively. The patients were divided into two groups as early onset preeclampsia (≤34 weeks) and late onset preeclampsia (>34 weeks). Statistical analyses were used to compare demographic data, maternal risk factors and neonatal outcomes between the two groups. Results: Out of 92 patients, 45 (49%) were in the early onset preeclampsia and 47 (51%) were in the late onset preeclampsia groups. Cesarean delivery and intrauterine growth retardation (IUGR) rates were significantly higher in the early onset preeclampsia group (p=0.01, p=0.025). High body mass index was an independent risk factor for late onset preeclampsia in the logistic regression analysis (p=0.012). Neonatal morbidities and hospitalization rates in the neonatal intensive care unit (NICU) were significantly higher in the early onset preeclampsia group (p<0.05, p=0.005, respectively). In addition, in the logistic regression analysis, it was found that early onset preeclampsia significantly increased the risks of IUGR (OR 2.96; 95% CL: 1.12–7.81), being small for gestational age (OR 2.5; 95% CL: 1.05–5.95), respiratory distress syndrome (OR 15.35; 95% CL: 3.06–76.99), patent ductus arteriosus (OR 11.43; 95% CL: 1.36–96.16) and hospitalization in the NICU (OR 2.48; 95% CL: 1.06–5.77). Conclusion: Early-onset preeclampsia was found to be an important risk factor for adverse neonatal outcomes while high body mass index during pregnancy was associated with late-onset preeclampsia.

Keywords: Early-onset, late-onset, preeclampsia, risk factors, neonatal outcomes
DOI :10.26650/jchild.2020.3.809801   IUP :10.26650/jchild.2020.3.809801    Full Text (PDF)

Erken ve Geç Başlangıçlı Preeklampside Risk Faktörleri ve Neonatal Sonuçların Karşılaştırılması

Özgül Bulut, Meryem Hocaoğlu, Nurgül Bulut, Selin Demirer, Abdulkadir Turgut, Fahri Ovalı

Amaç: Erken başlangıçlı ve geç başlangıçlı preeklampside maternal risk faktörleri ve erken dönem neonatal sonuçların karşılaştırılması. Gereç ve Yöntem: Hastanemizde preeklampsi tanısı almış hastalar retrospektif olarak değerlendirildi. Hastalar erken başlangıçlı preeklampsi (≤34 hafta) ve geç başlangıçlı preeklampsi (>34 hafta) olmak üzere 2 gruba ayrıldı. İki grup arasında demografik data, maternal risk faktörleri ve neonatal sonuçları karşılaştırmak için istatistiksel analiz yapıldı. Bulgular: Preeklampsi tanısı alan 92 hastanın, 45 (%49)’i erken başlangıçlı preeklampsi ve 47 (%51)’si geç başlangıçlı preeklampsi idi. Erken başlangıçlı preeklampsi grubunda, sezaryen doğum ve intrauterin büyüme kısıtlılığı (İUBK) oranları anlamlı şekilde daha yüksek bulundu (p=0.01, p=0.025). Lojistik regresyon analizinde, gebelikte yüksek vücut kitle indeksinin geç başlangıçlı preeklampsi için bağımsız bir risk faktörü olduğu saptandı (p=0.012). Erken başlangıçlı preeklampsi grubunda, neonatal morbidite ve yenidoğan yoğun bakım ünitesine (YDYBÜ) yatış oranları anlamlı şekilde daha yüksek bulundu (p<0.05, p=0.005, sırasıyla). Bunun yanında, lojistik regresyon analizinde erken başlangıçlı preeklampsinin, İUBK (OR 2.96; 95% CL: 1.12–7.81), SGA (OR 2.5; 95% CL: 1.05–5.95), respiratuar distres sendromu (OR 15.34; 95% CL: 3.06–76.99), patent duktus arteriosus (OR 11.43; 95% CL: 1.36–96.16) ve YDYBÜ’ne yatış (OR 2.48; 95% CL: 1.06–5.77) riskini anlamlı şekilde artırdığı saptandı. Sonuç: Çalışmamızda, erken başlangıçlı preeklampsi, olumsuz neonatal sonuçlar için önemli bir risk faktörü olarak bulunurken, gebelikte yüksek vücut kitle indeksi geç başlangıçlı preeklampsi ile ilişkili bulundu. 

Keywords: Erken başlangıç, geç başlangıç, preeklampsi, risk faktörleri, neonatal sonuçlar

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APA

Bulut, Ö., Hocaoğlu, M., Bulut, N., Demirer, S., Turgut, A., & Ovalı, F. (2020). Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Journal of Child, 20(3), 100-106. https://doi.org/10.26650/jchild.2020.3.809801


AMA

Bulut Ö, Hocaoğlu M, Bulut N, Demirer S, Turgut A, Ovalı F. Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Journal of Child. 2020;20(3):100-106. https://doi.org/10.26650/jchild.2020.3.809801


ABNT

Bulut, Ö.; Hocaoğlu, M.; Bulut, N.; Demirer, S.; Turgut, A.; Ovalı, F. Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Journal of Child, [Publisher Location], v. 20, n. 3, p. 100-106, 2020.


Chicago: Author-Date Style

Bulut, Özgül, and Meryem Hocaoğlu and Nurgül Bulut and Selin Demirer and Abdulkadir Turgut and Fahri Ovalı. 2020. “Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia.” Journal of Child 20, no. 3: 100-106. https://doi.org/10.26650/jchild.2020.3.809801


Chicago: Humanities Style

Bulut, Özgül, and Meryem Hocaoğlu and Nurgül Bulut and Selin Demirer and Abdulkadir Turgut and Fahri Ovalı. “Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia.” Journal of Child 20, no. 3 (Apr. 2024): 100-106. https://doi.org/10.26650/jchild.2020.3.809801


Harvard: Australian Style

Bulut, Ö & Hocaoğlu, M & Bulut, N & Demirer, S & Turgut, A & Ovalı, F 2020, 'Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia', Journal of Child, vol. 20, no. 3, pp. 100-106, viewed 19 Apr. 2024, https://doi.org/10.26650/jchild.2020.3.809801


Harvard: Author-Date Style

Bulut, Ö. and Hocaoğlu, M. and Bulut, N. and Demirer, S. and Turgut, A. and Ovalı, F. (2020) ‘Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia’, Journal of Child, 20(3), pp. 100-106. https://doi.org/10.26650/jchild.2020.3.809801 (19 Apr. 2024).


MLA

Bulut, Özgül, and Meryem Hocaoğlu and Nurgül Bulut and Selin Demirer and Abdulkadir Turgut and Fahri Ovalı. “Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia.” Journal of Child, vol. 20, no. 3, 2020, pp. 100-106. [Database Container], https://doi.org/10.26650/jchild.2020.3.809801


Vancouver

Bulut Ö, Hocaoğlu M, Bulut N, Demirer S, Turgut A, Ovalı F. Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Journal of Child [Internet]. 19 Apr. 2024 [cited 19 Apr. 2024];20(3):100-106. Available from: https://doi.org/10.26650/jchild.2020.3.809801 doi: 10.26650/jchild.2020.3.809801


ISNAD

Bulut, Özgül - Hocaoğlu, Meryem - Bulut, Nurgül - Demirer, Selin - Turgut, Abdulkadir - Ovalı, Fahri. “Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia”. Journal of Child 20/3 (Apr. 2024): 100-106. https://doi.org/10.26650/jchild.2020.3.809801



TIMELINE


Submitted13.10.2020
Accepted24.11.2020
Published Online30.12.2020

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