Research Article


DOI :10.26650/IUITFD.2020.0091   IUP :10.26650/IUITFD.2020.0091    Full Text (PDF)

WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?

Cemile İdizÖzlem YılmazNurdan GülSakin TekinRamazan ÇakmakMeryem Merve Ören ÇelikSena GürkaşMehmet Akif KaranGülistan Bahat Öztürkİlhan Satman

Objective: Our study aimed to determine the factors related to frailty in elderly adults having been diagnosed with type 2 diabetes mellitus. Material and Method: A total of 108 people aged 65 and over, diagnosed with type 2 diabetes, were included in the study. The frailty of the participants was evaluated with the FRAIL questionnaire, their nutritional status was evaluated with the Mini Nutrition Assessment Short Form (MNA-SF), the depression status with the Patient Health Questionnaire-2 (PHQ2) and the Geriatric Depression Scale Short Form (GDS-SF), while the quality of life was evaluated with the EuroQol-5 Dimension (EQ5D) and Scoring the EQ-VAS, and personal care status were evaluated with Basic Activities of Daily Living (BADL) and Instrumental Activities of Daily Living (IADL) forms. Results: Sleep problems, fear of falling, presence of urinary incontinence, PHQ2, GDS-SF, and EQ5D scores were significantly higher; the MNASF score was significantly lower in the frail group than the values in the non-frail group (p<0.05, for all). Conclusion: The relationship between frailty and malnutrition, decreased quality of life, and increased depression in elderly diabetic patients was demonstrated in the present study. As all these factors have a place in the management of diabetes,awareness should be raised and frailty screening should be expanded in elderly diabetics. 

DOI :10.26650/IUITFD.2020.0091   IUP :10.26650/IUITFD.2020.0091    Full Text (PDF)

TİP 2 DİYABETLİ YAŞLI BİREYLERDE KIRILGANLIĞI ETKİLEYEN FAKTÖRLER NELERDİR?

Cemile İdizÖzlem YılmazNurdan GülSakin TekinRamazan ÇakmakMeryem Merve Ören ÇelikSena GürkaşMehmet Akif KaranGülistan Bahat Öztürkİlhan Satman

Amaç: Çalışmamızın amacı tip 2 diyabet tanısı almış yaşlı erişkinlerde kırılganlıkla ilgili faktörleri belirlemektir. Gereç ve Yöntem: Çalışmaya 65 yaş ve üstü, tip 2 diyabet tanısı almış 108 kişi dahil edildi. Katılımcıların kırılganlığı FRAIL anketi ile değerlendirilmiş, beslenme durumu Mini Beslenme Değerlendirme Kısa Formu (MNA-SF) ile, depresyon durumu Hasta Sağlığı Anketi-2 (PHQ2) ve Geriatrik Depresyon Ölçeği Kısa Formu (GDS-SF) ile değerlendirilirken, yaşam kalitesi EuroQol-5 Boyut (EQ5D) ve EQ VAS puanlaması ile, kişisel bakım durumları ise Günlük Yaşamın Temel Aktiviteleri (BADL) ve Günlük Yaşamın Enstrümantal Aktiviteleri (IADL) formları ile değerlendirilmiştir. Bulgular: Kırılgan grupta, kırılgan olmayanlara göre uyku sorunları, düşme korkusu, idrar kaçırma, PHQ2, GDS-SF ve EQ5D skorları anlamlı olarak yüksek; MNASF skoru ise anlamlı olarak düşüktü (p<0,05, tüm kıyaslamalar için). Sonuç: Bu çalışmada yaşlı diyabetik hastalarda kırılganlık ile malnütrisyon, azalan yaşam kalitesi ve artmış depresyon arasındaki ilişki gösterilmiştir. Tüm bu faktörlerin diyabet yönetiminde bir yeri olduğu için farkındalık artırılmalı ve yaşlı diyabetlilerde kırılganlık taraması genişletilmelidir.


PDF View

References

  • 1. Kinsella K, Wan H. Census Bureau: International Population Reports. An Aging World: 2008, Washington: U.S. Government Printing Office, DC, (serial online) 2009 (cited 2020 January 04). Available from: URL: https://www.census. gov/prod/2009pubs/p95-09-1.pdf. google scholar
  • 2. HelpAge International. State of the world’s older people 2002, (serial online) 2002 (cited 2020 January 02). Available from: URL: http://www.helpage.org/Researchandpolicy/ Stateoftheworldsolderpeople/. google scholar
  • 3. Turkiye Istatistik Kurumu. Yıllara, Yaş grubu ve cinsiyete göre nüfus- genel nüfus sayımları, (serial online) 2019 (cited 2020 March 03). Available from: URL: http://www.tuik.gov.tr/ UstMenu.do?metod:temelist/ google scholar
  • 4. Satman İ. Diabetes mellitus tanı ve izleminde yeni kriterler ve belirlenme gerekçeleri. Turkiye Klinikleri J Int Med Sci 2007;3(3):1-15. 5. King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21(9):1414-31. [CrossRef] google scholar
  • 6. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87(1):4-14. [CrossRef] google scholar
  • 7. Steyn NP, Mann J, Bennett PH, Temple N, Zimmet P, Tuomilehto J, et al. Diet, nutrition, and the prevention of type 2 diabetes. Public Health Nutr 2004;7(1A):147-65. [CrossRef] google scholar
  • 8. Ikwuobe J, Bellary S, Griffiths HR. Innovative biomarkers for predicting type 2 diabetes mellitus: relevance to dietary management of frailty in older adults. Biogerontology 2016;17(3):511-27. [CrossRef] google scholar
  • 9. Satman I, Omer B, Tutuncu Y, Kalaca S, Gedik S, Dinccag N, et al. Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults. Eur J Epidemiol 2013;28(2):169-80. [CrossRef] google scholar
  • 10. International Diabetes Federation. IDF Diabetes Atlas 6th edition (serial online) 2013 (cited 2020 March 03). Available from: URL: https://www.idf.org/e-library/epidemiologyresearch/diabetes-atlas/19-atlas-6th-edition.html/. google scholar
  • 11. International Diabetes Federation. IDF Diabetes Atlas 8th edition (serial online) 2017 (cited 2020 March 03). Available from: URL: http://diabetesatlas.org/IDF_Diabetes_ Atlas_8e_interactive_EN/. google scholar
  • 12. Ozdemir S, Öztürk ZA, Türkbeyler İH, Şirin F, Göl M. Klinikte Yatan Geriatrik Hastalarda Farklı Ölçekler Kullanılarak Kırılganlık Prevalansının Belirlenmesi. KSU Medical Journal 2017;12(3):1-5. [CrossRef] google scholar
  • 13. Casals C, Casals Sánchez JL, Suárez Cadenas E, AguilarTrujillo MP, Estébanez Carvajal FM, Vázquez-Sánchez MÁ. Frailty in older adults with type 2 diabetes mellitus and its relation with glucemic control, lipid profile blood pressure, balance, disability grade and nutritional status. Nutr Hosp 2018;35(4):820-826. google scholar
  • 14. Cobo A, Vázquez LA, Reviriego J, Rodríguez-Mañas L. Impact of frailty in older patients with diabetes mellitus: An overview. Endocrinol Nutr 2016;63(6):291-303. [CrossRef] google scholar
  • 15. Chao CT, Wang J, Chien KL. Cohort of Geriatric Nephrology in NTUH (COGENT) study group. Both pre-frailty and frailty increase healthcare utilization and adverse health outcomes in patients with type 2 diabetes mellitus. Cardiovasc Diabetol 2018;17(1):130. [CrossRef] google scholar
  • 16. Chode S, Malmstrom TK, Miller DK, Morley JE. Frailty, diabetes, and mortality in middle-aged African Americans. J Nutr Health Aging 2016;20(8):854-9. [CrossRef] google scholar
  • 17. Morley JE, Malmstrom TK, Miller DK. A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. The Journal of Nutrition, Health & Aging 2012;16(7):601-8. [CrossRef] google scholar
  • 18. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56(3):M146- 56. [CrossRef] google scholar
  • 19. Kaiser MJ, Bauer JM, Ramsch C, Uter W, Guigoz Y, Cederholm T, et al. Validation of the Mini Nutritional Assessment short-form (MNA-SF): a practical tool for identification of nutritional status. J Nutr Health Aging 2009;13(9):782-8. [CrossRef] google scholar
  • 20. McManus D, Pipkin SS, Whooley MA. Screening for depression in patients with coronary heart disease (data from the Heart and Soul Study). Am J Cardiol 2005;96(8):1076-81. [CrossRef] google scholar
  • 21. Lelito RH, Palumbo LO, Hanley M. Psychometric evaluation of a brief geriatric depression screen. Aging & Mental Health 2001;5(4):387-93. [CrossRef] google scholar
  • 22. EuroQol Group: EuroQol--a new facility for the measurement of health-related quality of life. Health Policy 1990;16(3):199-208. [CrossRef] google scholar
  • 23. Izumi M, Akifusa S, Ganaha S, Yamashita Y. Activities of daily living decline is a predictor of lowered coughing ability and correlates with rehabilitative effect of tongue cleaning on coughing ability. Odontology 2019;107(1):393-400. [CrossRef] google scholar
  • 24. Cho CY, Alessi CA, Cho M, Aronow HU, Stuck AE, Rubenstein LZ, et al. The association between chronic illness and functional change among participants in a comprehensive geriatric assessment program. J Am Geriatr Soc 1998;46(6):677-82. [CrossRef] google scholar
  • 25. Siriwardhana DD, Hardoon S, Rait G, Weerasinghe MC, Walters KR. Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and metaanalysis. BMJ Open 2018;8(3):e018195. [CrossRef] google scholar
  • 26. Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 2012;60(8):1487-92. [CrossRef] google scholar
  • 27. Saum KU, Dieffenbach AK, Muller H, Holleczek B, Hauer K, Brenner H. Frailty prevalence and 10-year survival in community-dwelling older adults: results from the ESTHER cohort study. Eur J Epidemiol 2014;29(3):171-9. [CrossRef] google scholar
  • 28. Perkisas S, Vandewoude M. Where frailty meets diabetes. Diabetes Metab Res Rev 2016;32(1):261-7. [CrossRef] google scholar
  • 29. Acosta-Benito MA, Sevilla-Machuca I. Using prefrailty to detect early disability. J Family Community Med 2016;23(3):140-4. [CrossRef] google scholar
  • 30. Kojima G, Iliffe S, Taniguchi Y, Shimada H, Rakugi H, Walters K. Prevalence of frailty in Japan: A systematic review and meta-analysis. J Epidemiol 2017;27(8):347-53. [CrossRef] google scholar
  • 31. Li Y, Zou Y, Wang S, Li J, Jing X, Yang M, et al. A Pilot Study of the FRAIL Scale on Predicting Outcomes in Chinese Elderly People With Type 2 Diabetes. J Am Med Dir Assoc 2015;16(8):714.e7-714.e12. [CrossRef] google scholar
  • 32. Nishimura A, Harashima SI, Hosoda K, Arai H, Inagaki N. Sex-related differences in frailty factors in older persons with type 2 diabetes: a cross-sectional study. Ther Adv Endocrinol Metab 2019;10:2042018819833304. [CrossRef] google scholar
  • 33. Gordon EH, Peel NM, Samanta M, Theou O, Howlett SE, Hubbard RE. Sex differences in frailty: A systematic review and meta-analysis. Exp Gerontol 2017;89:30-40. [CrossRef] google scholar
  • 34. Moreira BS, Sampaio RF, Diz JB, Bastone AC, Ferriolli E, Neri AL, et al. Factors associated with fear of falling in community-dwelling older adults with and without diabetes mellitus: Findings from the Frailty in Brazilian Older People Study (FIBRA-BR). Exp Gerontol 2017;89:103-11. [CrossRef] google scholar
  • 35. Ensrud KE, Blackwell TL, Redline S, Ancoli-Israel S, Paudel ML, Cawthon PM, et al. Sleep disturbances and frailty status in older community-dwelling men. J Am Geriatr Soc 2009;57(11):2085-93. [CrossRef] google scholar
  • 36. Suskind AM. Frailty and Lower Urinary Tract Symptoms. Curr Urol Rep 2017;18(9):67. [CrossRef] google scholar
  • 37. Kondrup J, Allison S, Elia M, Vellas B, Plauth M. ESPEN Guidelines for Nutrition Screening 2002. Clin Nutr 2003;22(4):415-21. [CrossRef] google scholar
  • 38. Rubenstein L, Harker j, Salva A, Guigoz Y, Vellas B. Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF). J Gerontol a Biol Med Sci 2001;56(6):366-72. [CrossRef] google scholar
  • 39. Helminen H, Luukkaala T, Saarnio J, Nuotio MS. Predictive value of the mini-nutritional assessment short form (MNASF) and nutritional risk screening (NRS2002) in hip fracture. Eur J Clin Nutr 2019;73(1):112-20. [CrossRef] google scholar
  • 40. Wei K, Thein FS, Nyunt MSZ, Gao Q, Wee SL, Ng TP. Nutritional and Frailty State Transitions in the Singapore Longitudinal Aging Study. J Nutr Health Aging 2018;22(10):1221-7. [CrossRef] google scholar
  • 41. Lorenzo-López L, Maseda A, de Labra C, Regueiro-Folgueira L, Rodríguez-Villamil JL, Millán-Calenti JC. Nutritional determinants of frailty in older adults: A systematic review. BMC Geriatr 2017;17(1):108. [CrossRef] google scholar
  • 42. Cruz-Jentoft AJ, Woo J. Nutritional interventions to prevent and treat frailty. Curr Opin Clin Nutr Metab Care 2019;22(3):191-5. [CrossRef] google scholar
  • 43. Laur CV, McNicholl T, Valaitis R, Keller HH. Malnutrition or frailty? Overlap and evidence gaps in the diagnosis and treatment of frailty and malnutrition. Appl Physiol Nutr Metab 2017;42(5):449-58. [CrossRef] google scholar
  • 44. Soysal P, Veronese N, Thompson T, Kahl KG, Fernandes BS, Prina AM, et al. Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Res Rev 2017;36:78-87. [CrossRef] google scholar
  • 45. Almeida OP, McCaul K, Hankey GJ, Yeap BB, Golledge J, Norman PE, et al. Duration of diabetes and its association with depression in later life: The Health In Men Study (HIMS). Maturitas 2016;86:3-9. [CrossRef] google scholar
  • 46. Kojima G, Iliffe S, Jivraj S, Walters K. Association between frailty and quality of life among community-dwelling older people: a systematic review and meta-analysis. J Epidemiol Community Health 2016;70(7):716-21. [CrossRef] google scholar
  • 47. Crocker TF, Brown L, Clegg A, Farley K, Franklin M, Simpkins S, et al. Quality of life is substantially worse for communitydwelling older people living with frailty: systematic review and meta-analysis. Qual Life Res 2019;28(8):2041-56. [CrossRef] google scholar
  • 48. Kim S, Won CW, Kim BS, Kim S, Yoo J, Byun S, et al. EuroQol Visual Analogue Scale (EQ-VAS) as a Predicting Tool for Frailty in Older Korean Adults: The Korean Frailty an Aging Cohort Study (KFACS). J Nutr Health Aging 2018;22(10):1275-80. [CrossRef] google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

İdiz, C., Yılmaz, Ö., Gül, N., Tekin, S., Çakmak, R., Ören Çelik, M.M., Gürkaş, S., Karan, M.A., Bahat Öztürk, G., & Satman, İ. (2021). WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. Journal of Istanbul Faculty of Medicine, 84(1), 1-8. https://doi.org/10.26650/IUITFD.2020.0091


AMA

İdiz C, Yılmaz Ö, Gül N, Tekin S, Çakmak R, Ören Çelik M M, Gürkaş S, Karan M A, Bahat Öztürk G, Satman İ. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. Journal of Istanbul Faculty of Medicine. 2021;84(1):1-8. https://doi.org/10.26650/IUITFD.2020.0091


ABNT

İdiz, C.; Yılmaz, Ö.; Gül, N.; Tekin, S.; Çakmak, R.; Ören Çelik, M.M.; Gürkaş, S.; Karan, M.A.; Bahat Öztürk, G.; Satman, İ. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 84, n. 1, p. 1-8, 2021.


Chicago: Author-Date Style

İdiz, Cemile, and Özlem Yılmaz and Nurdan Gül and Sakin Tekin and Ramazan Çakmak and Meryem Merve Ören Çelik and Sena Gürkaş and Mehmet Akif Karan and Gülistan Bahat Öztürk and İlhan Satman. 2021. “WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?.” Journal of Istanbul Faculty of Medicine 84, no. 1: 1-8. https://doi.org/10.26650/IUITFD.2020.0091


Chicago: Humanities Style

İdiz, Cemile, and Özlem Yılmaz and Nurdan Gül and Sakin Tekin and Ramazan Çakmak and Meryem Merve Ören Çelik and Sena Gürkaş and Mehmet Akif Karan and Gülistan Bahat Öztürk and İlhan Satman. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?.” Journal of Istanbul Faculty of Medicine 84, no. 1 (Apr. 2024): 1-8. https://doi.org/10.26650/IUITFD.2020.0091


Harvard: Australian Style

İdiz, C & Yılmaz, Ö & Gül, N & Tekin, S & Çakmak, R & Ören Çelik, MM & Gürkaş, S & Karan, MA & Bahat Öztürk, G & Satman, İ 2021, 'WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?', Journal of Istanbul Faculty of Medicine, vol. 84, no. 1, pp. 1-8, viewed 26 Apr. 2024, https://doi.org/10.26650/IUITFD.2020.0091


Harvard: Author-Date Style

İdiz, C. and Yılmaz, Ö. and Gül, N. and Tekin, S. and Çakmak, R. and Ören Çelik, M.M. and Gürkaş, S. and Karan, M.A. and Bahat Öztürk, G. and Satman, İ. (2021) ‘WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?’, Journal of Istanbul Faculty of Medicine, 84(1), pp. 1-8. https://doi.org/10.26650/IUITFD.2020.0091 (26 Apr. 2024).


MLA

İdiz, Cemile, and Özlem Yılmaz and Nurdan Gül and Sakin Tekin and Ramazan Çakmak and Meryem Merve Ören Çelik and Sena Gürkaş and Mehmet Akif Karan and Gülistan Bahat Öztürk and İlhan Satman. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?.” Journal of Istanbul Faculty of Medicine, vol. 84, no. 1, 2021, pp. 1-8. [Database Container], https://doi.org/10.26650/IUITFD.2020.0091


Vancouver

İdiz C, Yılmaz Ö, Gül N, Tekin S, Çakmak R, Ören Çelik MM, Gürkaş S, Karan MA, Bahat Öztürk G, Satman İ. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. Journal of Istanbul Faculty of Medicine [Internet]. 26 Apr. 2024 [cited 26 Apr. 2024];84(1):1-8. Available from: https://doi.org/10.26650/IUITFD.2020.0091 doi: 10.26650/IUITFD.2020.0091


ISNAD

İdiz, Cemile - Yılmaz, Özlem - Gül, Nurdan - Tekin, Sakin - Çakmak, Ramazan - Ören Çelik, MeryemMerve - Gürkaş, Sena - Karan, MehmetAkif - Bahat Öztürk, Gülistan - Satman, İlhan. WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?”. Journal of Istanbul Faculty of Medicine 84/1 (Apr. 2024): 1-8. https://doi.org/10.26650/IUITFD.2020.0091



TIMELINE


Submitted24.07.2020
Accepted13.10.2020
Published Online15.01.2021

LICENCE


Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.