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The subcronic effects of acetamipride on the global DNA methylation levels in Sprague-Dawley rat brain and liver

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İstanbul Journal of Pharmacy (Istanbul J Pharm) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of İstanbul University Faculty of Pharmacy and it is published triannually on April, August, and December. The publication language of the journal is English.

İstanbul Journal of Pharmacy (Istanbul J Pharm) aims to contribute to the literature by publishing manuscripts at the highest scientific level on all fields of pharmaceutical sciences. The journal publishes original articles, short reports, letters to the editor and reviews.

The target audience of the journal includes specialists and professionals working and interested in all disciplines of pharmaceutical, also medicinal, biological and chemical sciences.

The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Committee of Medical Journal Editors (ICMJE), World Association of Medical Editors (WAME), Council of Science Editors (CSE), Committee on Publication Ethics (COPE), European Association of Science Editors (EASE), and National Information Standards Organization (NISO). The journal is in conformity with the Principles of Transparency and Best Practice in Scholarly Publishing (doaj.org/bestpractice).

İstanbul Journal of Pharmacy is currently indexed in Web of Science-Emerging Sources Citation Index, TUBITAK ULAKBIM TR Index and CAS database.
 
Processing and publication are free of charge with the journal. No fees are requested from the authors at any point throughout the evaluation and publication process. All manuscripts must be submitted via the online submission system, which is available at http://dergipark.gov.tr/iujp. The journal guidelines, technical information, and the required forms are available on the journal’s web page.

All expenses of the journal are covered by the İstanbul University Faculty of Pharmacy. Potential advertisers should contact the Editorial Office. Advertisement images are published only upon the Editor-in-Chief’s approval.

Statements or opinions expressed in the manuscripts published in the journal reflect the views of the author(s) and not the opinions of the İstanbul University Faculty of Pharmacy, editors, editorial board, and/or publisher; the editors, editorial board, and publisher disclaim any responsibility or liability for such materials.

İstanbul Journal of Pharmacy is an open access publication and the journal’s publication model is based on Budapest Open Access Initiative (BOAI) declaration. Journal’s archive is available online, free of charge at http://istanbul.edu.tr:8080/en/journal/ijp/home. İstanbul Journal of Pharmacy's content is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


​

Editor in Chief: Prof. Emine AKALIN URUŞAK

Address: İstanbul University, Faculty of Pharmacy, Department of Pharmaceutical Botany, Beyazıt, 34116, Fatih İstanbul

Phone: +90 212 440 02 75

Fax: +90 212 440 02 52

E-mail: akaline@istanbul.edu.tr                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       

Emine

Prof. Dr.

Emerging Sources Citation Index (ESCI)

EBSCO

TR Dizin

CAS Source Index

SOBIAD

Cabells Journalytics

Gale Cengage

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İstanbul Journal of Pharmacy

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İstanbul Journal of Pharmacy (Istanbul J Pharm) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of İstanbul University Faculty of Pharmacy and it is published triannually on April, August, and December. The publication language of the journal is English.İstanbul Journal of Pharmacy (Istanbul J Pharm) aims to contribute to the literature by publishing manuscripts at the highest scientific level on all fields of pharmaceutical sciences. The journal publishes original articles, short reports, letters to the editor and reviews.The target audience of the journal includes specialists and professionals working and interested in all disciplines of pharmaceutical, also medicinal, biological and chemical sciences.

Amaç ve Kapsam

Web of Science - Emerging Sources Citation Index (ESCI)TÜBİTAK-ULAKBİM TR DizinCAS Source IndexSOBİADEBSCO Central &amp; Eastern European Academic SourceEBSCO Academic Search UltimateCabells Journalytics <a href="https://go.gale.com/ps/dispAdvSearch.do?userGroupName=anon~84c5a0c7&amp;prodId=AONE" target="_blank">Gale Cengage</a>

Dizinler

The journal is committed to upholding the highest standards of publication ethics and pays regard to Principles of Transparency and Best Practice in Scholarly Publishing published by the <a href="https://publicationethics.org/" target="_blank">Committee on Publication Ethics (COPE)</a>, the <a href="https://doaj.org/apply/transparency/#principles-of-transparency-and-best-practice-in-scholarly-publishing" target="_blank">Directory of Open Access Journals (DOAJ)</a>, the <a href="https://oaspa.org/" target="_blank">Open Access Scholarly Publishers Association (OASPA)</a>, and the <a href="https://www.wame.org/" target="_blank">World Association of Medical Editors (WAME)</a> on <a href="https://publicationethics.org/resources/guidelines-new/principles-transparency-and-best-practice-scholarly-publishing" target="_blank" style="background-color: transparent;">https://publicationethics.org/resources/guidelines-new/principles-transparency-and-best-practice-scholarly-publishing</a>The subjects covered in the manuscripts submitted to the Journal for publication must be in accordance with the aim and scope of the Journal. Only those manuscripts approved by every individual author and that were not published before in or sent to another journal, are accepted for evaluation.Changing the name of an author (omission, addition or order) in papers submitted to the Journal requires written permission of all declared authors.Plagiarism, duplication, fraud authorship/denied authorship, research/data fabrication, salami slicing/salami publication, breaching of copyrights, prevailing conflict of interest are unethical behaviors. All manuscripts not in accordance with the accepted ethical standards will be removed from the publication. This also contains any possible malpractice discovered after the publication.Plagiarism Submitted manuscripts that pass preliminary control are scanned for plagiarism using iThenticate software. If plagiarism/self-plagiarism will be found authors will be informed. Editors may resubmit manuscript for similarity check at any peer-review or production stage if required. High similarity scores may lead to rejection of a manuscript before and even after acceptance. Depending on the type of article and the percentage of similarity score taken from each article, the overall similarity score is generally expected to be less than 15 or 20%.Double Blind Peer-Review After plagiarism check, the eligible ones are evaluated by the editors-in-chief for their originality, methodology, the importance of the subject covered and compliance with the journal scope. The editor provides a fair double-blind peer review of the submitted articles and hands over the papers matching the formal rules to at least two national/international referees for evaluation and gives green light for publication upon modification by the authors in accordance with the referees’ claims.

Politikalar

The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Council of Medical Journal Editors (<a href="http://www.icmje.org/" target="_blank">ICMJE</a>), the World Association of Medical Editors (<a href="http://www.wame.org/" target="_blank">WAME</a>), the Council of Science Editors (<a href="http://www.councilscienceeditors.org/" target="_blank">CSE</a>), the Committee on Publication Ethics (<a href="http://publicationethics.org/" target="_blank">COPE</a>), the European Association of Science Editors (<a href="http://www.ease.org.uk/" target="_blank">EASE</a>), and National Information Standards Organization (<a href="http://www.niso.org/home/" target="_blank">NISO</a>). The journal conforms to the Principles of Transparency and Best Practice in Scholarly Publishing (<a href="doaj.org/bestpractice" target="_blank">doaj.org/bestpractice</a>).Originality, high scientific quality, and citation potential are the most important criteria for a manuscript to be accepted for publication. Manuscripts submitted for evaluation should not have been previously presented or already published in an electronic or printed medium. The journal should be informed of manuscripts that have been submitted to another journal for evaluation and rejected for publication. The submission of previous reviewer reports will expedite the evaluation process. Manuscripts that have been presented in a meeting should be submitted with detailed information on the organization, including the name, date, and location of the organization.

The journal is an open access journal and all content is freely available without charge to the user or his/her institution. Except for commercial purposes, users are allowed to read, download, copy, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the <a href="https://www.budapestopenaccessinitiative.org/read" target="_blank" style="background-color: transparent;">BOAI</a> definition of open access.The open access articles in the journal are licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (<a href="https://creativecommons.org/licenses/by-nc/4.0/deed.en" target="_blank" style="background-color: transparent;">CC BY-NC 4.0</a>) license.

All expenses of the journal are covered by the Istanbul University. Processing and publication are free of charge with the journal. There is no article processing charges or submission fees for any submitted or accepted articles.

Authors publishing with the journal retain the copyright to their work licensed under the Creative Commons Attribution-NonCommercial 4.0 International license (<a href="https://creativecommons.org/licenses/by-nc/4.0/" target="_blank">CC BY-NC 4.0</a>) (<a href="https://creativecommons.org/licenses/by-nc/4.0/" target="_blank">https://creativecommons.org/licenses/by-nc/4.0/</a> ) and grant the Publisher non-exclusive commercial right to publish the work. CC BY-NC 4.0 license permits unrestricted, non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Editor should consider publishing correction if minor errors that do not effect the results, interpretations and conclusions of the published paper are detected. Editor should consider retraction if major errors and/or misconduction that invalidate results and conclusions are detected.Editor should consider issuing an expression of concern if there is evidence of research or publication misconduct by the authors; there is evidence that the findings are not reliable and institutions of the authors do not investigate the case or the possible investigation seems to be unfair or nonconclusive. The guidelines of <a href="https://publicationethics.org/resources/flowcharts/complete-set-english" target="_blank">COPE</a> and <a href="https://www.icmje.org/recommendations/" target="_blank">ICJME</a> are taken into consideration regarding correction, retractions or expression of concern.

To guarantee that all papers published in the journal are maintained and permanently accessible, articles are stored in Dergipark which serves as a  national archival web site and at the same time permits LOCKSS to  collect, preserve, and serve the content.Additionally, authors are encouraged to self-archive the final PDF version of their articles in open electronic archives with  that conform to standards of Open Archives Initiative (<a href="https://www.openarchives.org/" target="_blank">https://www.openarchives.org/</a>). Authors should provide a link from the deposited version to the URL of IUPress journal website.

An approval of research protocols by the Ethics Committee in accordance with international agreements (World Medical Association Declaration of Helsinki “<a href="https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/" target="_blank">Ethical Principles for Medical Research Involving Human Subjects</a>,” amended in October 2013, <a href="http://www.wma.net/" target="_blank">www.wma.net</a>) is required for experimental, clinical, and drug studies. If required, ethics committee reports or an equivalent official document will be requested from the authors. For manuscripts concerning experimental research on humans, a statement should be included that shows that written informed consent of patients and volunteers was obtained following a detailed explanation of the procedures that they may undergo. For studies carried out on animals, the measures taken to prevent pain and suffering of the animals should be stated clearly. Information on patient consent, the name of the ethics committee, and the ethics committee approval number should also be stated in the Materials and Methods section of the manuscript. It is the authors’ responsibility to carefully protect the patients’ anonymity. For photographs that may reveal the identity of the patients, signed releases of the patient or of their legal representative should be enclosed.All submissions are screened by a similarity detection software (iThenticate by CrossCheck) at any point during the peer-review or production process.Even if you are the author of the phrases or sentences, the text should not have unacceptable similarity with the previously published data.When you are discussing others' (or your own) previous work, please make sure that you cite the material correctly in every instance.In the event of alleged or suspected research misconduct, e.g., plagiarism, citation manipulation, and data falsification/fabrication, the Editorial Board will follow and act in accordance with COPE guidelines.

Etik

İstanbul Journal of Pharmacy  adheres to the highest standards in research ethics and follows the principles of international research ethics as defined below. The authors are responsible for the compliance of the manuscripts with the ethical rules.-    Principles of integrity, quality and ransparency should be sustained in designing the research, reviewing the design and conducting the research.-    The research team and participants should be fully informed about the aim, methods, possible uses and requirements of the research and risks of participation in research.-    The confidentiality of the information provided by the research participants and the confidentiality of the respondents should be ensured. The research should be designed to protect the autonomy and dignity of the participants.-    Research participants should participate in the research voluntarily, not under any coercion.-    Any possible harm to participants must be avoided. The research should be planned in such a way that the participants are not at risk.-    The independence of research must be clear; and any conflict of interest or must be disclosed.-    In experimental studies with human subjects, written informed consent of the participants who decide to participate in the research must be obtained. In the case of children and those under wardship or with confirmed insanity, legal custodian’s assent must be obtained.-    If the study is to be carried out in any institution or organization, approval must be obtained from this institution or organization.-    In studies with human subject, it must be noted in the method’s section of the manuscript that the informed consent of the participants and ethics committee approval from the institution where the study has been conducted have been obtained.

The Journal takes as principle to comply with the ethical standards of <a href="https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/" target="_blank">World Medical Association (WMA) Declaration of Helsinki – Ethical Principles for Medical Research Involving Human Subjects</a> and <a href="https://www.wma.net/policies-post/wma-statement-on-animal-use-in-biomedical-research/" target="_blank">WMA Statement on Animal Use in Biomedical Research</a>.An approval of research protocols by the Ethics Committee in accordance with international standards mentioned above is required for experimental, clinical, and drug studies and for some case reports. If required, ethics committee reports or an equivalent official document will be requested from the authors. For manuscripts concerning experimental research on humans, a statement should be included that shows that written informed consent of patients and volunteers was obtained following a detailed explanation of the procedures that they may undergo. For studies carried out on animals, the measures taken to prevent pain and suffering of the animals should be stated clearly. Information on patient consent, the name of the ethics committee, and the ethics committee approval number should also be stated in the Materials and Methods section of the manuscript. It is the authors’ responsibility to carefully protect the patients’ anonymity. For photographs that may reveal the identity of the patients, signed releases of the patient or of their legal representative should be enclosed.

The journal requires the authors and all individuals taking part in the evaluation process to disclose any existing or potential conflict of interest (such as financial ties, academic commitments, personal relationships, institutional affiliations) that could unduly influence one’s responsibilities.  To disclose potential conflicts of interest, the <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/A001FA4618B040128D696E342B5C2199" target="_blank">ICMJE Potential Conflict of Interest Disclosure Form</a> should be filled in and submitted by authors as explained in the Author Form of the journal. Cases of a potential conflict of interest are resolved  within the scope of <a href="https://publicationethics.org/resources/flowcharts/complete-set-english" target="_blank">COPE Conflict of Interest Flowcharts</a> and <a href="https://www.icmje.org/about-icmje/faqs/conflict-of-interest-disclosure-forms/" target="_blank">ICMJE Conflict of Interest guidelines</a>Besides conflict of interest, all financial support received to carry out research must be declared while submitting the paper.

It is authors’ responsibility to ensure that the article is in accordance with scientific and ethical standards and rules. And authors must ensure that submitted work is original. They must certify that the manuscript has not previously been published elsewhere or is not currently being considered for publication elsewhere, in any language. Applicable copyright laws and conventions must be followed. Copyright material (e.g. tables, figures or extensive quotations) must be reproduced only with appropriate permission and acknowledgement. Any work or words of other authors, contributors, or sources must be appropriately credited and referenced.All the authors of a submitted manuscript must have direct scientific and academic contribution to the manuscript. The author(s) of the original research articles is defined as a person who is significantly involved in “conceptualization and design of the study”, “collecting the data”, “analyzing the data”, “writing the manuscript”, “reviewing the manuscript with a critical perspective” and “planning/conducting the study of the manuscript and/or revising it”. Fund raising, data collection or supervision of the research group are not sufficient roles to be accepted as an author. The author(s) must meet all these criteria described above. The order of names in the author list of an article must be a co-decision and it must be indicated in the <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/8B799B8ED7884FC299C2CA4D31712D2E" target="_blank">Copyright Agreement Form.</a> The individuals who do not meet the authorship criteria but contributed to the study must take place in the acknowledgement section. Individuals providing technical support, assisting writing, providing a general support, providing material or financial support are examples to be indicated in acknowledgement section.All authors must disclose all issues concerning financial relationship, conflict of interest, and competing interest that may potentially influence the results of the research or scientific judgment.When an author discovers a significant error or inaccuracy in his/her own published paper, it is the author’s obligation to promptly cooperate with the Editor to provide retractions or corrections of mistakes.

Editor-in-Chief evaluates manuscripts for their scientific content without regard to ethnic origin, gender, sexual orientation, citizenship, religious belief or political philosophy of the authors. He/She provides a fair double-blind peer review of the submitted articles for publication and ensures that all the information related to submitted manuscripts is kept as confidential before publishing.Editor-in-Chief is responsible for the contents and overall quality of the publication. He/She must publish errata pages or make corrections when needed.Editor-in-Chief does not allow any conflicts of interest between the authors, editors and reviewers. Only he has the full authority to assign a reviewer and is responsible for final decision for publication of the manuscripts in the Journal.Reviewers must have no conflict of interest with respect to the research, the authors and/or the research funders. Their judgments must be objective.Reviewers must ensure that all the information related to submitted manuscripts is kept as confidential and must report to the editor if they are aware of copyright infringement and plagiarism on the author’s side.A reviewer who feels unqualified to review the topic of a manuscript or knows that its prompt review will be impossible should notify the editor and excuse himself from the review process.The editor informs the reviewers that the manuscripts are confidential information and that this is a privileged interaction. The reviewers and editorial board cannot discuss the manuscripts with other persons. The anonymity of the referees must be ensured. In particular situations, the editor may share the review of one reviewer with other reviewers to clarify a particular point.

Only those manuscripts approved by its every individual author and that were not published before in or sent to another journal, are accepted for evaluation.Submitted manuscripts that pass preliminary control are scanned for plagiarism using iThenticate software. After plagiarism check, the eligible ones are evaluated by editor-in-chief for their originality, methodology, the importance of the subject covered and compliance with the journal scope.The editor hands over the papers matching the formal rules to at least two national/international referees for double-blind peer review evaluation and gives green light for publication upon modification by the authors in accordance with the referees’ claims.

Hakemlik Hakkında

Editor-in-Chief evaluates manuscripts for their scientific content without regard to ethnic origin, gender, sexual orientation, citizenship, religious belief or political philosophy of the authors. He/She provides a fair double-blind peer review of the submitted articles for publication and ensures that all the information related to submitted manuscripts is kept as confidential before publishing.Editor-in-Chief is responsible for the contents and overall quality of the publication. He/She must publish errata pages or make corrections when needed.Editor-in-Chief does not allow any conflicts of interest between the authors, editors and reviewers. Only he has the full authority to assign a reviewer and is responsible for final decision for publication of the manuscripts in the Journal.Reviewers must have no conflict of interest with respect to the research, the authors and/or the research funders. Their judgments must be objective.Reviewers must ensure that all the information related to submitted manuscripts is kept as confidential and must report to the editor if they are aware of copyright infringement and plagiarism on the author’s side.A reviewer who feels unqualified to review the topic of a manuscript or knows that its prompt review will be impossible should notify the editor and excuse himself from the review process.The editor informs the reviewers that the manuscripts are confidential information and that this is a privileged interaction. The reviewers and editorial board cannot discuss the manuscripts with other persons. The anonymity of the referees must be ensured. In particular situations, the editor may share the review of one reviewer with other reviewers to clarify a particular point.

Only those manuscripts approved by its every individual author and that were not published before in or sent to another journal, are accepted for evaluation.Submitted manuscripts that pass preliminary control are scanned for plagiarism using iThenticate software. After plagiarism check, the eligible ones are evaluated by editor-in-chief for their originality, methodology, the importance of the subject covered and compliance with the journal scope.  The selected manuscripts are sent to at least two national/international referees for evaluation and publication decision is given by editor-in-chief  upon modification by the authors in accordance with the referees’ claims.Editor-in-chief evaluates manuscripts for their scientific content without regard to ethnic origin, gender, sexual orientation, citizenship, religious belief or political philosophy of the authors and ensures a fair double-blind peer review of the selected manuscripts. Editor in chief does not allow any conflicts of interest between the authors, editors and reviewers and is responsible for final decision for publication of the manuscripts in the Journal.Reviewers’ judgments must be objective. Reviewers’ comments on the following aspects are expected while conducting the review.-    Does the manuscript contain new and significant information?-    Does the abstract clearly and accurately describe the content of the manuscript?-    Is the problem significant and concisely stated?-    Are the methods described comprehensively?-    Are the interpretations and consclusions justified by the results?-    Is adequate references made to other Works in the field?-    Is the language acceptable?Reviewers must ensure that all the information related to submitted manuscripts is kept as confidential and must report to the editor if they are aware of copyright infringement and plagiarism on the author’s side.A reviewer who feels unqualified to review the topic of a manuscript or knows that its prompt review will be impossible should notify the editor and excuse himself from the review process.The editor informs the reviewers that the manuscripts are confidential information and that this is a privileged interaction. The reviewers and editorial board cannot discuss the manuscripts with other persons. The anonymity of the referees is important.

The manuscripts should be prepared in accordance with <a href="http://www.icmje.org/icmje-recommendations.pdf" target="_blank">ICMJE-Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals</a>  Author(s) are required to prepare manuscripts in accordance with the <a href="http://www.consort-statement.org/" target="_blank">CONSORT</a> guidelines for randomized research studies, <a href="https://www.strobe-statement.org/" target="_blank">STROBE</a> guidelines for observational original research studies, <a href="https://www.equator-network.org/reporting-guidelines/stard/" target="_blank">STARD</a> guidelines for studies on diagnostic accuracy, <a href="http://www.prisma-statement.org/" target="_blank">PRISMA</a> guidelines for systematic reviews and meta-analysis, <a href="https://arriveguidelines.org/" target="_blank">ARRIVE</a> guidelines for experimental animal studies, and <a href="https://www.cdc.gov/trendstatement/index.html" target="_blank">TREND</a> guidelines for non-randomized public behavior.Manuscripts can only be submitted through the journal’s online manuscript submission and evaluation system, available at <a href="https://dergipark.org.tr/tr/pub/iujp" target="_blank">https://dergipark.org.tr/tr/pub/iujp</a>. Manuscripts submitted via any other medium will not be evaluated.​Manuscripts submitted to the journal will first go through a technical evaluation process where the editorial office staff will ensure that the manuscript has been prepared and submitted in accordance with the journal’s guidelines. Submissions that do not conform to the journal’s guidelines will be returned to the submitting author with technical correction requests.Authors are required to submit the following:•    <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/8B799B8ED7884FC299C2CA4D31712D2E" target="_blank">Copyright Agreement Form</a>•    <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/B9125D8C36BD4C5B9E53DB1F67DD1E0D" target="_blank">Author Form</a>•    <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1C172B465BD74943BB806CC07B5584FC" target="_blank">Title Page</a>during the initial submission.Preparation of the Manuscript<a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1C172B465BD74943BB806CC07B5584FC" target="_blank">Title page</a>: A separate title page should be submitted with all submissions and this page should include:•    The full title of the manuscript as well as a short title (running head) of no more than 50 characters,•    Name(s), affiliations, and highest academic degree(s) and ORCID ID(s) of the author(s),•    Grant information and detailed information on the other sources of support,•    Name, address, telephone (including the mobile phone number) and fax numbers, and email address of the corresponding author,•    Acknowledgment of the individuals who contributed to the preparation of the manuscript but who do not fulfill the authorship criteria.Abstract: An structured abstract should be submitted with Original Articles (Background and Aims, Methods, Results, Conclusion).  Please check Table 1 below for word count specifications.Keywords: Each submission must be accompanied by a minimum of three to a maximum of six keywords for subject indexing at the end of the abstract. The keywords should be listed in full without abbreviations. The keywords should be selected from the National Library of Medicine, Medical Subject Headings database (<a href="https://www.nlm.nih.gov/mesh/MBrowser.html" target="_blank">https://www.nlm.nih.gov/mesh/MBrowser.html</a>).

Yazım Kuralları

Original Articles: This is the most important type of article since it provides new information based on original research. The main text of original articles should be structured with Introduction, Materials and Methods, Results, Discussion, and Conclusion subheadings.  Results and Discussion sections can be combined under “Result and Discussion” heading. Please check Table 1 for the limitations for Original Articles.Statistical analysis to support conclusions is usually necessary. Statistical analyses must be conducted in accordance with international statistical reporting standards (Altman DG, Gore SM, Gardner MJ, Pocock SJ. Statistical guidelines for contributors to medical journals. Br Med J 1983: 7; 1489-93). Information on statistical analyses with specified statistical software and descriptive details of the chemical used should be provided with a separate subheading under the Materials and Methods section.Units should be prepared in accordance with the International System of Units (SI).Editorial Comments: Editorial comments aim to provide a brief critical commentary by reviewers with expertise or with high reputation in the topic of the research article published in the journal. Authors are selected and invited by the journal to provide such comments. Abstract, Keywords, and Tables, Figures, Images, and other media are not included.Review Articles: Reviews prepared by authors who have extensive knowledge on a particular field and whose scientific background has been translated into a high volume of publications with a high citation potential are welcomed. These authors may even be invited by the journal. Reviews should describe, discuss, and evaluate the current level of knowledge of a topic in clinical practice and should guide future studies. Please check Table 1 for the limitations for Review Articles.Short Papers: Please check Table 1 for the limitations for Short Papers.Letters to the Editor: This type of manuscript discusses important parts, overlooked aspects, or lacking parts of a previously published article. Articles on subjects within the scope of the journal that might attract the readers’ attention, particularly educative cases, may also be submitted in the form of a “Letter to the Editor.” Readers can also present their comments on the published manuscripts in the form of a “Letter to the Editor.” Abstract, Keywords, and Tables, Figures, Images, and other media should not be included. The text should be unstructured. The manuscript that is being commented on must be properly cited within this manuscript.Table 1. Limitations for each manuscript type<table border="0" cellspacing="0" cellpadding="0" style="font-size: 13px;text-align: left;"><tbody><tr><td width="158"> Type of manuscript</td><td width="158"> Word limit</td><td width="158"> Abstract word limit</td><td width="158"> Table limit</td><td width="158"> Figure limit</td></tr><tr><td>  Original Article</td><td>3500</td><td> 250 (Stuctured)</td><td> 6</td><td> 7 or total of 15 images</td></tr><tr><td>  Review Article</td><td>5000</td><td> 250 (Unstuctured)</td><td> 6</td><td> 10 or total of 20 images</td></tr><tr><td> Short Paper</td><td>1000</td><td> 200</td><td> No tables</td><td> 10 or total of 20 images</td></tr><tr><td> Letter to the Editor</td><td>500</td><td> No abstract</td><td> No tables</td><td> No media</td></tr></tbody></table>

Tables should be included in the main document, presented after the reference list, and they should be numbered consecutively in the order they are referred to within the main text. A descriptive title must be placed above the tables. Abbreviations used in the tables should be defined below the tables by footnotes (even if they are defined within the main text). Tables should be created using the “insert table” command of the word processing software and they should be arranged clearly to provide easy reading. Data presented in the tables should not be a repetition of the data presented within the main text but should be supporting the main text.

Figures, graphics, and photographs should be submitted as separate files (in TIFF or JPEG format) through the submission system. The files should not be embedded in a Word document or the main document. When there are figure subunits, the subunits should not be merged to form a single image. Each subunit should be submitted separately through the submission system. Images should not be labeled (a, b, c, etc.) to indicate figure subunits. Thick and thin arrows, arrowheads, stars, asterisks, and similar marks can be used on the images to support figure legends. Like the rest of the submission, the figures too should be blind. Any information within the images that may indicate an individual or institution should be blinded. The minimum resolution of each submitted figure should be 300 DPI. To prevent delays in the evaluation process, all submitted figures should be clear in resolution and large in size (minimum dimensions: 100 × 100 mm). Figure legends should be listed at the end of the main document.All acronyms, abbreviations, and symbols used in the manuscript must follow international rules and should be defined at first use, both in the abstract and in the main text. The abbreviation should be provided in parentheses following the definition.For plant materials, herbarium name (or acronym), number, name and surname of the person who identified the plant materials should be indicated in the Materials and Methods section of the manuscript.When a drug, product, hardware, or software program is mentioned within the main text, product information, including the name of the product, the producer of the product, and city and the country of the company (including the state if in USA), should be provided in parentheses in the following format: “Discovery St PET/CT scanner (General Electric, Milwaukee, WI, USA)”All references, tables, and figures should be referred to within the main text, and they should be numbered consecutively in the order they are referred to within the main text.Limitations, drawbacks, and the shortcomings of original articles should be mentioned in the Discussion section before the conclusion paragraph.

When submitting a revised version of a paper, the author must submit a detailed “Response to the reviewers” that states point by point how each issue raised by the reviewers has been covered and where it can be found (each reviewer’s comment, followed by the author’s reply and line numbers where the changes have been made) as well as an annotated copy of the main document. Revised manuscripts must be submitted within 30 days from the date of the decision letter. If the revised version of the manuscript is not submitted within the allocated time, the revision option may be cancelled. If the submitting author(s) believe that additional time is required, they should request this extension before the initial 30-day period is over.Accepted manuscripts are copy-edited for grammar, punctuation, and format. Once the publication process of a manuscript is completed, it is published online on the journal’s webpage as an ahead-of-print publication before it is included in its scheduled issue. A PDF proof of the accepted manuscript is sent to the corresponding author and their publication approval is requested within 2 days of their receipt of the proof.

Reference Style and Formatİstanbul Journal of Pharmacy complies with APA (American Psychological Association) style 6th Edition for referencing and quoting. For more information:-    American Psychological Association. (2010). Publication manual of the American PsychologicalAssociation (6th ed.). Washington, DC: APA.-    <a href="http://www.apastyle.org/" target="_blank">http://www.apastyle.org</a>Accuracy of citation is the author’s responsibility. All references should be cited in text. Reference list must be in alphabetical order. Type references in the style shown below.Citations in the TextCitations must be indicated with the author surname and publication year within the parenthesis.If more than one citation is made within the same paranthesis, separate them with (;).Samples:More than one citation;(Esin et al., 2002; Karasar, 1995)Citation with one author;(Akyolcu, 2007)Citation with two authors;(Sayıner &amp; Demirci, 2007)Citation with three, four, five authors;First citation in the text: (Ailen, Ciambrune, &amp; Welch, 2000) Subsequent citations in the text: (Ailen et al., 2000)Citations with more than six authors;(Çavdar et al., 2003)Citations in the ReferenceAll the citations done in the text should be listed in the References section in alphabetical order of author surname without numbering. Below given examples should be considered in citing the references.Basic Reference TypesBooka) Turkish BookKarasar, N. (1995). Araştırmalarda rapor hazırlama (8th ed.) [Preparing research reports]. Ankara, Turkey: 3A Eğitim Danışmanlık Ltd.b) Book Translated into TurkishMucchielli, A. (1991). Zihniyetler [Mindsets] (A. Kotil, Trans.). İstanbul, Turkey: İletişim Yayınları.c) Edited BookÖren, T., Üney, T., &amp; Çölkesen, R. (Eds.). (2006). Türkiye bilişim ansiklopedisi [Turkish Encyclopedia of Informatics]. İstanbul, Turkey: Papatya Yayıncılık.d) Turkish Book with Multiple AuthorsTonta, Y., Bitirim, Y., &amp; Sever, H. (2002). Türkçe arama motorlarında performans değerlendirme [Performance evaluation in Turkish search engines]. Ankara, Turkey: Total Bilişim.e) Book in EnglishKamien R., &amp; Kamien A. (2014). Music: An appreciation. New York, NY: McGraw-Hill Education.f) Chapter in an Edited BookBassett, C. (2006). Cultural studies and new media. In G. Hall &amp; C. Birchall (Eds.), New cultural studies: Adventures in theory (pp. 220–237). Edinburgh, UK: Edinburgh University Press.g) Chapter in an Edited Book in TurkishErkmen, T. (2012). Örgüt kültürü: Fonksiyonları, öğeleri, işletme yönetimi ve liderlikteki önemi [Organization culture: Its functions, elements and importance in leadership and business management]. In M. Zencirkıran (Ed.), Örgüt sosyolojisi [Organization sociology] (pp. 233–263). Bursa, Turkey: Dora Basım Yayın.h) Book with the same organization as author and publisherAmerican Psychological Association. (2009). Publication manual of the American psychological association (6th ed.). Washington, DC: Author.Articlea) Turkish ArticleMutlu, B., &amp; Savaşer, S. (2007). Çocuğu ameliyat sonrası yoğun bakımda olan ebeveynlerde stres nedenleri ve azaltma girişimleri [Source and intervention reduction of stress for parents whose children are in intensive care unit after surgery]. Istanbul University Florence Nightingale Journal of Nursing, 15(60), 179–182.b) English ArticleOrlacchio, A., Campos-Cavieres, M., Pashev, I., &amp; Munn, E.A. (1979). Some kinetic and other properties of the isoenzymes of aspartate aminotransferase isolated from sheep liver. Biochemical Journal, 177, 583-593. c) Journal Article with DOI and More Than Seven AuthorsLal, H., Cunningham, A. L., Godeaux, O., Chlibek, R., Diez-Domingo, J., Hwang, S.-J. ... Heineman, T. C. (2015). Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. New England Journal of Medicine, 372, 2087–2096. http://dx.doi.org/10.1056/NEJMoa1501184d) Journal Article from Web, without DOISidani, S. (2003). Enhancing the evaluation of nursing care effectiveness. Canadian Journal of Nursing Research, 35(3), 26–38. Retrieved from http://cjnr.mcgill.cae) Journal Article wih DOITurner, S. J. (2010). Website statistics 2.0: Using Google Analytics to measure library website effectiveness. Technical Services Quarterly, 27, 261–278. http://dx.doi.org/10.1080/07317131003765910f) Advance Online PublicationSmith, J. A. (2010). Citing advance online publication: A review. Journal of Psychology. Advance online publication. http://dx.doi.org/10.1037/a45d7867Doctoral Dissertation, Master’s Thesis, Presentation, Proceedinga) Dissertation/Thesis from a Commercial DatabaseVan Brunt, D. (1997). Networked consumer health information systems (Doctoral dissertation). Available from ProQuest Dissertations and Theses database. (UMI No. 9943436)b) Dissertation/Thesis from an Institutional DatabaseYaylalı-Yıldız, B. (2014). University campuses as places of potential publicness: Exploring the politicals, social and cultural practices in Ege University (Doctoral dissertation). Retrieved from http://library.iyte.edu.tr/tr/hizli-erisim/iyte-tez-portalic) Dissertation/Thesis from WebTonta, Y. A. (1992). An analysis of search failures in online library catalogs (Doctoral dissertation, University of California, Berkeley). Retrieved from http://yunus.hacettepe.edu.tr/~tonta/yayinlar /phd/ickapak.htmld) Dissertation/Thesis abstracted in Dissertations Abstracts InternationalAppelbaum, L. G. (2005). Three studies of human information processing: Texture amplifica&#173;tion, motion representation, and figure-ground segregation. Dissertation Abstracts International: Section B. Sciences and Engineering, 65(10), 5428.e) Conference Paper Abstract Retrieved OnlineLiu, S. (2005, May). Defending against business crises with the help of intelligent agent based early warning solutions. Paper presented at the Seventh International Conference on Enterprise Information Systems, Miami, FL. Abstract retrieved from http://www.iceis.org/iceis2005/abstracts_2005.htmf) Conference Paper - In Regularly Published Proceedings and Retrieved OnlineHerculano-Houzel, S., Collins, C. E., Wong, P., Kaas, J. H., &amp; Lent, R. (2008). The basic nonuniformity of the cerebral cortex. Proceedings of the National Academy of Sciences, 105, 12593–12598. http://dx.doi.org/10.1073/pnas.0805417105g) Proceeding in Book FormParsons, O. A., Pryzwansky, W. B., Weinstein, D. J., &amp; Wiens, A. N. (1995). Taxonomy for psychology. In J. N. Reich, H. Sands, &amp; A. N. Wiens (Eds.), Education and training beyond the doctoral degree: Proceedings of the American Psychological Association National Conference on Postdoctoral Education and Training in Psychology (pp. 45–50). Washington, DC: American Psychological Association.Other Sourcesa) Web PageBordwell, D. (2013, June 18). David Koepp: Making the world movie-sized [Web log post]. Retrieved from http://www.davidbordwell.net/blog/page/27/

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E-ISSN	2587-2087
Yayın Aralığı	Yılda Üç Sayı
Editör	Emine Akalın
İstanbul Journal of Pharmacy (Istanbul J Pharm) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of İstanbul University Faculty of Pharmacy and it is published triannually on April, August, and December. The publication language of the journal is English. İstanbul Journal of Pharmacy (Istanbul J Pharm) aims to contribute to the literature by publishing manuscripts at the highest scientific level on all fields of pharmaceutical sciences. The journal publishes original articles, short reports, letters to the editor and reviews. The target audience of the journal includes specialists and professionals working and interested in all disciplines of pharmaceutical, also medicinal, biological and chemical sciences. The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Committee of Medi devamı

İstanbul Journal of Pharmacy

SON SAYI

Plenary Lectures

Oral Presentations

Poster Presentations

ERKEN GÖRÜNÜM

Some histone deacetylase inhibitors protect against dextran sulphate sodium-induced hepatotoxicity in mice

Safety and possible risks of tea tree oil from a toxicological perspective

ÖNE ÇIKAN

The assessment of in vitro cardiotoxic potentials for synthetic cannabinoid, AM-2201

Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones

ÇOK OKUNAN

Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey

The subcronic effects of acetamipride on the global DNA methylation levels in Sprague-Dawley rat brain and liver

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DUYURULAR

ABONE OL

İLETİŞİM