Sağlık Bilimlerinde İleri Araştırmalar Dergisi

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DOI :10.26650/JARHS2020-S1-0007   IUP :10.26650/JARHS2020-S1-0007    Tam Metin (PDF)

COVID-19 ve Koagülopati

Ayşegül Ünüvar

Ağır Akut Solunum Sendromu Coronavirus 2’nin (SARS-CoV2) etken patojen olduğu SARS-CoV2 enfeksiyonu (COVID-19) yeni bir enfeksiyon hastalığıdır. Akciğerler COVID-19 için hedef organdır; akut akciğer hasarı solunum yetmezliğine ilerleyebilir ve çoklu organ yetersizliği de gelişebilir. COVID-19; inflamasyon artışı, trombosit aktivasyonu, endotel disfonksiyonu ve kan akımında stazın etkisiyle hem venöz hem de arteriyel sistemde tromboz gelişimine neden olabilir. Bu derleme, COVID-19 pandemisinin ilk aylarındaki mevcut güncel bilgiler ışığı altında hazırlandı. Ancak, trombotik komplikasyonla ilgili çalışmalar da dahil mevcut kanıtlar çok sınırlıdır, başlıca az sayıda hastaların olduğu retrospektif analizlere dayalıdır, daha güçlü ve yüksek kalitede yeni çalışmalara ihtiyaç vardır. 

Anahtar Kelimeler: COVID-19, koagülopati, profilaksi, tedavi
DOI :10.26650/JARHS2020-S1-0007   IUP :10.26650/JARHS2020-S1-0007    Tam Metin (PDF)

COVID-19 and Coagulopathy

Ayşegül Ünüvar

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is the causative pathogen of a new infectious disease, COVID-19. The lungs are the target organ for COVID-19; acute lung injury can progress to respiratory failure, and multiorgan failure can also occur. COVID-19 may predispose to both venous and arterial thromboembolic disease due to coagulation activation caused by a combination of excessive inflammation, platelet activation, endothelial dysfunction, and stasis in blood flow. This review was prepared in the light of the current information available in the first months of the COVID-19 pandemic. However, the existing evidence, including studies on thrombotic complications, is very limited and derived primarily from small and retrospective analyses, and more strong and high quality new studies are required.

Anahtar Kelimeler: COVID-19, Coagulopathy, prophylaxis, treatment

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Referanslar

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DIŞA AKTAR



APA

Ünüvar, A. (2020). COVID-19 ve Koagülopati. Sağlık Bilimlerinde İleri Araştırmalar Dergisi, 3(1), 53-62. https://doi.org/10.26650/JARHS2020-S1-0007


AMA

Ünüvar A. COVID-19 ve Koagülopati. Sağlık Bilimlerinde İleri Araştırmalar Dergisi. 2020;3(1):53-62. https://doi.org/10.26650/JARHS2020-S1-0007


ABNT

Ünüvar, A. COVID-19 ve Koagülopati. Sağlık Bilimlerinde İleri Araştırmalar Dergisi, [Publisher Location], v. 3, n. 1, p. 53-62, 2020.


Chicago: Author-Date Style

Ünüvar, Ayşegül,. 2020. “COVID-19 ve Koagülopati.” Sağlık Bilimlerinde İleri Araştırmalar Dergisi 3, no. 1: 53-62. https://doi.org/10.26650/JARHS2020-S1-0007


Chicago: Humanities Style

Ünüvar, Ayşegül,. “COVID-19 ve Koagülopati.” Sağlık Bilimlerinde İleri Araştırmalar Dergisi 3, no. 1 (Apr. 2024): 53-62. https://doi.org/10.26650/JARHS2020-S1-0007


Harvard: Australian Style

Ünüvar, A 2020, 'COVID-19 ve Koagülopati', Sağlık Bilimlerinde İleri Araştırmalar Dergisi, vol. 3, no. 1, pp. 53-62, viewed 23 Apr. 2024, https://doi.org/10.26650/JARHS2020-S1-0007


Harvard: Author-Date Style

Ünüvar, A. (2020) ‘COVID-19 ve Koagülopati’, Sağlık Bilimlerinde İleri Araştırmalar Dergisi, 3(1), pp. 53-62. https://doi.org/10.26650/JARHS2020-S1-0007 (23 Apr. 2024).


MLA

Ünüvar, Ayşegül,. “COVID-19 ve Koagülopati.” Sağlık Bilimlerinde İleri Araştırmalar Dergisi, vol. 3, no. 1, 2020, pp. 53-62. [Database Container], https://doi.org/10.26650/JARHS2020-S1-0007


Vancouver

Ünüvar A. COVID-19 ve Koagülopati. Sağlık Bilimlerinde İleri Araştırmalar Dergisi [Internet]. 23 Apr. 2024 [cited 23 Apr. 2024];3(1):53-62. Available from: https://doi.org/10.26650/JARHS2020-S1-0007 doi: 10.26650/JARHS2020-S1-0007


ISNAD

Ünüvar, Ayşegül. “COVID-19 ve Koagülopati”. Sağlık Bilimlerinde İleri Araştırmalar Dergisi 3/1 (Apr. 2024): 53-62. https://doi.org/10.26650/JARHS2020-S1-0007



ZAMAN ÇİZELGESİ


Gönderim24.04.2020
Kabul04.05.2020
Çevrimiçi Yayınlanma15.05.2020

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