CHAPTER


DOI :10.26650/BB/CH22.2020.008.16   IUP :10.26650/BB/CH22.2020.008.16    Full Text (PDF)

COVID-19 and Head and Neck Cancer

Berkay ÇaytemelCömert ŞenErdinç UysalMurat Ulusan

Since the announcement of the new Coronavirus Disease (COVID-19) pandemic on March 11, 2020, almost all healthcare systems, including centers where head and neck cancer patients are treated and operated, have been globally affected. In most of the otolaryngology clinics, elective procedures and surgeries were suspended, and the number of patients examined in outpatient clinics decreased. Furthermore, cancer patients did not come to hospitals with the concern of being infected by COVID-19. This situation caused delays in the diagnosis, treatment and follow-up of head and neck cancer patients. Furthermore, studies have shown that being infected by COVID-19 during active treatment seriously increases the severity of the symptoms of the disease, the need for intensive care and mortality. When patients with head and neck cancer are evaluated separately from other cancer groups; because the head and neck cancers are usually associated with tobacco products and the incidence of head and neck cancers increases with age, patients are in the high risk group associated with COVID-19 regardless of the current cancer. In addition, some of these patients have tracheostomy which facilitates the spread of the disease. In this study, we tried to compile the information in the literature about how to carry out the diagnosis, treatment and follow-up of patients with head and neck cancer during the pandemic.


DOI :10.26650/BB/CH22.2020.008.16   IUP :10.26650/BB/CH22.2020.008.16    Full Text (PDF)

COVID-19 ve Baş-Boyun Kanseri

Berkay ÇaytemelCömert ŞenErdinç UysalMurat Ulusan

Yeni Koronavirüs Hastalığı’nın (COVID-19) 11 Mart 2020’de küresel salgın ilan edilmesinden bu yana; baş-boyun kanseri hastalarının takip ve opere edildiği merkezler de dahil olmak üzere neredeyse tüm sağlık sistemleri küresel olarak etkilenmiştir. Çoğu klinikte elektif günübirlik işlemler ve ameliyatlara ara verilmiş, muayene edilen hasta sayısında azaltmaya gidilmiştir. Kanser hastalarının SARS-CoV-2 ile enfekte olma endişesiyle hastanelere gitmemesi ve bu olguların ikinci planda kalması, baş-boyun kanseri hastalarının tanısında, tedavisinde ve takibinde gecikmelere yol açmıştır. Yapılan çalışmalarda, aktif tedavi (ameliyat veya radyoterapi/kemoterapi) esnasında COVID-19 geçirmenin hastalığın semptomlarının şiddetini, yoğun bakım ihtiyacını ve mortaliteyi ciddi artırmakta olduğu ortaya konulmuştur. Baş-boyun kanserli hastalar diğer kanser gruplarından ayrı olarak değerlendirildiğinde; genellikle tütün ürünleri ile ilişkili olduklarından ve yaş ile sıklığı arttığından, hastalar mevcut olan kanserden bağımsız olarak COVID-19 ile ilişkili yüksek risk grubundadırlar. Bu hastaların bir kısmında mevcut olan trakeostomi de SARS-CoV-2’nin yayılımı açısından yüksek risk oluşturmaktadır. Bu yazıda küresel salgın sürecinde baş-boyun kanserli hastaların tanısının, tedavisinin ve takibinin nasıl yürütülmesi gerektiği hakkında literatürdeki bilgiler derlenmiştir. 



References

  • 1. N. Zhu, D. Zhang, W. Wang, X. Li, B. Yang, J. Song, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020; 382: 727-33. google scholar
  • 2. Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020; 109: 102433. google scholar
  • 3. Coronavirus disease 2019 (COVID-19) Situation Report. Available from: https://www.who.int/emergencies/ diseases/novel-coronavirus-2019 google scholar
  • 4. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020; 382(13): 1199-207. google scholar
  • 5. Velavan TP, Meyer CG. COVID‐19 epidemic. Trop Med Int Health. 25: 278-80. google scholar
  • 6. Onder G, Rezza G, Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020; 323(18): 1775-6. google scholar
  • 7. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229): 1054-62. google scholar
  • 8. Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol. 2020; 21: 335-7. google scholar
  • 9. Desai A, Sachdeva S, Parekh T, Desai R. COVID-19 and cancer: lessons from a pooled meta-analysis. JCO Glob Oncol. 2020; 6: 557-9. google scholar
  • 10. Zhang L, Zhu F, Xie L, Wang C, Wang J, Chen R, et al. Clinical characteristics of COVID- 19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Ann Oncol. 2020; 31(7): 894-901. google scholar
  • 11. Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ. Cancer Statistics, 2003. CA Cancer J Clin. 2003; 53: 5-26. google scholar
  • 12. Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 2006; 24: 2137-50. google scholar
  • 13. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68(6): 394-424. google scholar
  • 14. Rettig EM, D’Souza G. Epidemiology of head and neck cancer. Surg Oncol Clin N Am. 2015; 24(3): 379-96. google scholar
  • 15. Ohannessian R, Duong TA, Odone A. Global Telemedicine Implementation and Integration Within Health Systems to Fight the COVID-19 Pandemic: A Call to Action. JMIR Public Health Surveill. 2020; 6(2): e18810. doi:10.2196/18810 google scholar
  • 16. Jensen AR, Nellemann HM, Overgaard J. Tumor progression in waiting time for 116 radiotherapy in head and neck cancer. Radiother Oncol. 2007; 84(1): 5-10. google scholar
  • 17. Wyatt RM, Beddoe AH, Dale RG. The effects of delays in radiotherapy treatment on tumour control. Phys Med Biol. 2003; 48: 139-55. google scholar
  • 18. Schutte HW, Heutink F, Wellenstein DJ, van den Broek GB, van den Hoogen FJA, Marres HAM, et al. Impact of time to diagnosis and treatment in head and neck cancer: a system- atic review. Otolaryngol Head Neck Surg. 2020; 162(4): 446-57. google scholar
  • 19. Chaves ALF, Castro AF, Marta GN, Junior GC, Ferris RL, Giglio RE, et al. Emergency changes in international guidelines on treatment for head and neck cancer patients during the COVID-19 pandemic. Oral Oncol. 2020; 107: 104734. doi:10.1016/j.oraloncology.2020.104734 google scholar
  • 20. Vukkadala N, Qian ZJ, Holsinger FC, Patel ZM, Rosenthal E. COVID-19 and the Otolaryngologist: Preliminary Evidence-Based Review. Laryngoscope. 2020;10.1002/lary.28672. doi:10.1002/lary.28672 google scholar
  • 21. Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, et al. SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients. N Engl J Med. 2020; 382(12): 1177-9. 152 COVID-19 ve Baş-Boyun Kanseri google scholar
  • 22. Cui C, Yao Q, Zhang D, Zhao Y, Zhang K, Nisenbaum E, et al. Approaching Otolaryngology Patients During the COVID-19 Pandemic. Otolaryngol Head Neck Surg. 2020; 163(1): 121-31. google scholar
  • 23. Canadian Association of Head & Neck Surgical Oncology (CAHNSO) Guidelines for Management of Head & Neck Cancer During the COVID-19 Pandemic. Available from: https://www.entcanada.org/ wp-content/ uploads/CAHNSO-Cancer-Mx-Guidelines-COVID- 19-Apr-3-2020-.pdf. Accessed April 7, 202 google scholar
  • 24. Topf MC, Shenson JA, Holsinger FC, Wald SH, Cianfichi LJ, Rosenthal EL, et al. Framework for prioritizing head and neck surgery during the COVID-19 pandemic. Head Neck. 2020; 42(6): 1159-67. 25. Kiong KL, Guo T, Yao CMKL, Gross ND, Hanasono MM, Ferrarotto R, et al. Changing practice patterns in head and neck oncologic surgery in the early COVID-19 era. Head & Neck. 2020; 42: 1179-86. google scholar
  • 26. Zuo MZ, Huang YG, Ma WH, Xue ZG, Zhang JQ, Gong YH, et al. Expert recommendations for tracheal intubation in critically ill patients with Noval coronavirus disease 2019. Chin Med Sci J. 2020; 35(2): 105-9. google scholar
  • 27. Risk for Otorhinolaryngologists. Available from: https://www.europe- anrhinologicsociety.org/?page_id=2143 google scholar
  • 28. Board on Health Sciences Policy; Institute of Medicine. The Use and Effectiveness of Powered Air Purifying Respirators in Health Care: Workshop Summary. Washington (DC): National Academies Press (US); 2015 May 7. doi: 10.17226/18990 google scholar
  • 29. O’Sullivan B, Huang SH, Siu LL, Waldron J, Zhao H, Perez-Ordonez B, et al. Deintensication candidate subgroups in human papillomavirus-related oropharyngeal cancer according to minimal risk of distant metastases. J Clin Oncol. 2013; 31: 543-50. google scholar
  • 30. Paul P, Deka H, Malakar AK, Halder B, Chakraborty S. Nasopharyngeal carcinoma: understanding its molecular biology at a fine scale. Eur J Cancer Prev. 2018; 27(1): 33-41. google scholar
  • 31. Higgins KM, Shah MD, Ogaick MJ, Enepekides D. Treatment of early-stage glottic cancer: meta-analysis comparison of laser excision versus radiotherapy. J Otolaryngol Head Neck Surg. 2009; 38: 603-12. google scholar
  • 32. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S, et al: Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res. 1996; 56(11): 2488-92. google scholar
  • 33. Simo R, Homer J, Clarke P, Mackenzie K, Paleri V, Pracy P, et al. Follow-up after treatment for head and neck cancer: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016; 130(S2): S208-S211. google scholar


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.