Experimed

SUBMITINFORMATION
EnglishTürkçe

Research Article


DOI :10.26650/experimed.1326693   IUP :10.26650/experimed.1326693    Full Text (PDF)

Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children

Lala Allahverdiyeva, Naile Efendiyeva, Afag Khalilova

Objective: Despite stunning advances in drug treatment, the present modern drugs that are used in the treatment of bronchial asthma don’t always achieve complete control over the disease. It may be useful to get support from complementary and alternative medicine (CAM) in such cases. CAM is understood as a non-traditional treatment, one of the varieties of which is speleotherapy. With the purpose of studying the therapeutic effect of speleotherapy in children, a treatment of speleotherapy was conducted for 50 children and adolescents suffering from atopic bronchial asthma.

Materials and Methods: To evaluate the effectiveness of speleotherapy, the following research methods were used: Spirometry method was used to assess the ventilation function of the lungs, nitric oxide in exhaled air was measured for the assessment of airway inflammation, and laboratory examination of patients were evaluated including Interleukin (IL)-5, IL-13 and Interferon-gamma (IFN-γ) in serum by using enzyme-linked immunosorbent assay (ELISA).

Results: As a result of the speleotherapy, patients improved their external respiratory function. The study also showed a positive impact with speleotherapy on exhaled nitric oxide and cytokine parameters in children with mild and moderate atopic bronchial asthma.

Conclusion: Speleotherapy, as a method of medical rehabilitation for patients with bronchial asthma, leads to a decrease in the number of attacks, reduces the use of bronchodilators, and improves the indicators of the function of external respiration.

Keywords: Allergy, asthma, children, nitric oxide, speleotherapy, spirometry

PDF View

References

  • 1. Campo P, Eguiluz Gracia I, Plaza Seron MC, Salas M, Rodnguez MJ, Perez Sanchez N, et al. Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis. Allergy 2019; 74(8): 1502-10. google scholar
  • 2. Akar-Ghibril N, Casale T, Custovic A, Phipatanakul W. Allergic endotypes and phenotypes of asthma [published correction appears in J Allergy Clin Immunol Pract. 2020; 8(5): 1779]. J Allergy Clin Immunol Pract 2020; 8(2): 429-40. google scholar
  • 3. Gong F, Zhu HY, Zhu J, Dong QJ, Huang X, Jiang DJ. Circulating CXCR5+CD4+ T cells participate in the IgE accumulation in allergic asthma. Immunol Lett 2018; 197: 9-14. google scholar
  • 4. Tran TN, Zeiger RS, Peters SP, Colice G, Newbold P, Goldman M, et al. Overlap of atopic, eosinophilic, and TH2-high asthma phenotypes in a general population with current asthma. Ann Allergy Asthma Immunol 2016; 116(1): 37-42. google scholar
  • Fjær EL, Landet ER, McNamara CL, Eikemo TA. The use of complementary and alternative medicine (CAM) in Europe. BMC Complement Med Ther 2020; 20(1): 108. google scholar
  • 6. Yildiz Y, Yavuz AY. Complementary and alternative medicine use in children with asthma. Complement Ther Clin Pract 2021; 43: 101353. google scholar
  • 7. Bjermer L. Complementary and alternative treatment of asthma. Breathe 2005; 1(4): 288-95. google scholar
  • 8. Beamon S, Falkenbach A, Fainburg G, Linde K. Speleotherapy for asthma. Cochrane Database Syst Rev 2001; (2): CD001741. google scholar
  • 9. Horowitz S. Salt cave therapy: Rediscovering the benefits of an old preservative. Alt Comp Ther 2010; 16(3): 158-62. google scholar
  • 10. Freidl J, Huber D, Braunschmid H, Romodow C, Pichler C, Weisböck-Erdheim R. et al Winter exercise and speleotherapy for allergy and asthma: a randomized controlled clinical trial. J Clin Med 2020; 9(10): 3311. google scholar
  • 11. Mçtel S, Kostrzon M, Adamiak J. Dynamic balance and chest mobility of older adults after speleotherapy combined with pulmonary rehabilitation, endurance and strength training-a prospective study in chronic respiratory diseases. Int J Environ Res Public Health 2022; 19(18): 11760. google scholar
  • 12. Escamilla-Gil JM, Fernandez-Nieto M, Acevedo N. Understanding the cellular sources of the fractional exhaled nitric oxide (FeNO) and its role as a biomarker of type 2 inflammation in asthma. Biomed Res Int 2022; 2022: 5753524. google scholar
  • 13. Akdis, C A, Arkwright PD, Brüggen MC, Busse W, Gadina M, Guttman-Yassky E., et al. Type 2 immunity in the skin and lungs. Allergy 2020; 75(7): 1582-605. google scholar
  • 14. ten Hacken NH, Oosterhoff Y, Kauffman HF, Guevarra L, Satoh T, Tollerud DJ, et al.Elevated serum interferon-Y in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation. Eur Respir J 1998; 11(2): 312-6. google scholar
  • 15. Gallucci M, Carbonara P, Pacilli AMG, di Palmo E, Ricci G, Nava S. Use of symptoms scores, spirometry, and other pulmonary function testing for asthma monitoring. Front Pediatr 2019; 7: 54. google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Allahverdiyeva, L., Efendiyeva, N., & Khalilova, A. (2023). Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children. Experimed, 13(3), 174-179. https://doi.org/10.26650/experimed.1326693


AMA

Allahverdiyeva L, Efendiyeva N, Khalilova A. Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children. Experimed. 2023;13(3):174-179. https://doi.org/10.26650/experimed.1326693


ABNT

Allahverdiyeva, L.; Efendiyeva, N.; Khalilova, A. Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children. Experimed, [Publisher Location], v. 13, n. 3, p. 174-179, 2023.


Chicago: Author-Date Style

Allahverdiyeva, Lala, and Naile Efendiyeva and Afag Khalilova. 2023. “Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children.” Experimed 13, no. 3: 174-179. https://doi.org/10.26650/experimed.1326693


Chicago: Humanities Style

Allahverdiyeva, Lala, and Naile Efendiyeva and Afag Khalilova. “Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children.” Experimed 13, no. 3 (Dec. 2024): 174-179. https://doi.org/10.26650/experimed.1326693


Harvard: Australian Style

Allahverdiyeva, L & Efendiyeva, N & Khalilova, A 2023, 'Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children', Experimed, vol. 13, no. 3, pp. 174-179, viewed 4 Dec. 2024, https://doi.org/10.26650/experimed.1326693


Harvard: Author-Date Style

Allahverdiyeva, L. and Efendiyeva, N. and Khalilova, A. (2023) ‘Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children’, Experimed, 13(3), pp. 174-179. https://doi.org/10.26650/experimed.1326693 (4 Dec. 2024).


MLA

Allahverdiyeva, Lala, and Naile Efendiyeva and Afag Khalilova. “Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children.” Experimed, vol. 13, no. 3, 2023, pp. 174-179. [Database Container], https://doi.org/10.26650/experimed.1326693


Vancouver

Allahverdiyeva L, Efendiyeva N, Khalilova A. Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children. Experimed [Internet]. 4 Dec. 2024 [cited 4 Dec. 2024];13(3):174-179. Available from: https://doi.org/10.26650/experimed.1326693 doi: 10.26650/experimed.1326693


ISNAD

Allahverdiyeva, Lala - Efendiyeva, Naile - Khalilova, Afag. “Efficacy of Speleotherapy on Atopic Bronchial Asthma in Children”. Experimed 13/3 (Dec. 2024): 174-179. https://doi.org/10.26650/experimed.1326693



TIMELINE


Submitted12.07.2023
Accepted01.11.2023
Published Online04.12.2023

LICENCE


Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.