Research Article


DOI :10.26650/IstanbulJPharm.2019.19012   IUP :10.26650/IstanbulJPharm.2019.19012    Full Text (PDF)

Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey

Turgay KolaçPerihan GürbüzGülsüm YetişZehra Deniz Çırak

Magistral drugs are preferred when present preparations are not sufficient. Even though their usage had decreased, it is predicted that magistral applications will be used more often in the future. In this study pharmacists and pharmacy employees working in 95 pharmacies in Malatya city center agreed to participate in the study (n=203) and filled in a questionnaire which was prepared according to literature. In the analysis of the obtained data, frequency and percentages were calculated using SPSS 24.0 program. It was observed that 11.1% of the pharmacies were close to a health center and 88.0% of the participants were preparing magistral drugs. 55.2% of the participants stated that they prepared magistral medications 1-2 times a week. According to the results, although the frequency varied with the localization of pharmacies, magistral drug preparation ratios were generally similar to those found in the literature. Preferred magistral drug forms were: creams (74.7%), pomades (69.8%) and solutions (54.7%). Of the participants who declared themselves to be inadequately skilled in magistral drug preparation, 19.5% said that the prescriptions were insufficient and 33.3% reported that the doctors’ prescriptions were incomplete or unreadable.


PDF View

References

  • Andaç A, Yaşayan G, Alarçin E, Okuyan B, Şahbaz S (2015). Eczane Mesul Müdürlerinin Magistral İlaç Hazırlama ile ilgili Bilgi ve Tutumlarının Değerlendirilmesi. J Pharm Res 19: 283-289. google scholar
  • Baytop T (1997). Laboratuvardan Fabrikaya: Türkiye’de İlaç Sanayii (1833-1954). Görsel Sanatlar Matbaacılık, İstanbul. google scholar
  • Brion F, Nunn A, Rieutord A (2003). Extemporaneous (magistral) preparation of oral medicines for children in European hospitals. Acta Paediatrica 92: 486-490. google scholar
  • Conroy S, Choonara I, Impicciatore P, Mohn A, Arnell H, Rane A, Anker J (2000). Survey of unlicensed and off label drug use in paediatric wards in European countries. BMJ 320: 79-82. google scholar
  • Emmerton L, Marriott J, Bessell T, Nissen L, Dean L (2005). Pharmacists and Prescribing Rights: Review of International Developments. J Pharm Pharmaceut Sci 8: 217-225. google scholar
  • Ergün H, Berk B, Uludağ M, Diler İ, Demir ED, Gümüşel B (2010). Türkiye’de eczanelerde hazırlanan (magistral) nitrogliserin merhemlerinin içerik ve sunum özellikleri yönünden değerlendirilmesi. Marmara Eczacılık Dergisi 14: 130-135. google scholar
  • Garcia MC, Manzo RH, Jimenez-Kairuz AF (2015). Extemporaneous benznidazole oral suspension prepared from commercially available tablets for treatment of Chagas disease in paediatric patients. Trop Med Int Health 20: 864-870. google scholar
  • Geçgil Ş (1991). Farmasötik Teknolojiye Başlangıç. Cihan Matbaacılık, İstanbul. google scholar
  • Gubara OA, Gubara TOA, Ayoub MO, Shayoub MEA, Hassan AME, Abd Alla Ah MEA, Ali MEA, Eldim Mahmmoud AN (2016). Extemporaneous Compounding: Attitudes of Community Pharmacists at Khartoum City. World J Pharm Res 5: 119-140. google scholar
  • Gubara OA, Shayoub MELA, Haj Elamin AE, Ayoub MO, Tumsah MAR, Masaad AMA, Shyoub AM (2018). Attitudes and Opinion of Hospital Pharmacists Towards Extemporaneous Compounding and Related Issues in Khartoum City: Part II. World J Pharm Res 7: 1-29. google scholar
  • Ilgın Ruhi H (2010). Meme Kanserinde Farmakogenetik. Turkiye Klinikleri J Med Sci 30: 16-21. google scholar
  • Kairuz T, Chhim S, Hasan F, Kumar K, Lal A, Patel R, Garg S (2007a). Extemporaneous compounding in a sample of New Zealand hospitals: a retrospective survey. N Z Med J 120: 1-9. google scholar
  • Kairuz T, Gargiulo D, Bunt C, Garg S (2007b). Quality, Safety and Efficacy in the ‘Off-Label’ Use of Medicines. Curr Drug Saf 2: 89-95. google scholar
  • Kristina S, Wiedyaningsih C, Widyakusuma N, Aditama H (2017). Extemporaneous compounding practice by pharmacists: a systematic review. Int J Pharm Pharm Sci 9: 42-46. google scholar
  • Leal AS, de BC Menezes MA, Dalmázio I, Sepe FP, Gomes CBT, Santana AS, Cunha LH, Jaćimović R (2012). Quality Control of Formulated Medicines. In Latest Research into Quality Control. InTech: 227-242. google scholar
  • Martin K, McPherson T, Fontane P, Berry T, Chereson R, Bilger R (2009). Independent Community Pharmacists’ Perspectives on Compounding in Contemporary Pharmacy Education. Am J Pharm Educ 73: 1-8. google scholar
  • Minghettiu P, Giudici E, Montanari L (2000). A Proposal to Improve the Supply of Orphan Drugs. Pharmacol Res 42: 33-37. google scholar
  • Neubert A, Wong I, Bonifazi A, Catapano M, Felisi M, Baiardi P, Ceci A (2008). Defining off-label and unlicensed use of medicines for children:Results of a Delphi survey. Pharmacol Res 58: 316-322. google scholar
  • Olguín H, Pérez C, Mendiola B, Garduño L, Ramírez E, Pérez J (2009). Comparative Bioavailability of Propafenone after Administration of a Magistral Suspension vs. Commercial Tablets in Healthy Volunteers. Arzneimittelforschung 59: 117-120. google scholar
  • Özbek H, Kırmızı N (2016). Magistral ilaçlar: Olgu sunumu. J For Med 30: 256-258. google scholar
  • Pereira AC, Miranda ES, Castilho SR, Futuro DO, Teixeira LA, Paula GR (2016). Magistral drugs in hospitalized newborns and children. Revista Paulista de Pediatria 34: 403-407. google scholar
  • Pérez R, García BS, Fernández-Llamazares CM, Artigao FB, Julian AN, Peña MJ (2016). The challenge of administering anti-tuberculosis treatment in infants and pre-school children, pTBred Magistral Project. Anales de Pediatría (English Edition) 85: 4-12. google scholar
  • Schellekens H, Aldosari M, Talsma H, Mastrobattista E (2017). Making individualized drugs a reality. Nat Biotechnol 35: 507-513. google scholar
  • Sellers S, Utian W (2014). Pharmacy Compounding Primer for Physicians Prescriber Beware. Climacteric 17: 19-21. google scholar
  • Sklenár Z, Scigel V, Horáčková K, Slanar O (2013). Compounded preparations with nystatin for oral and oromucosal administration. Acta Pol Pharm 70: 759-762. google scholar
  • Staubach P, Metz M (2013). Magistral formulations and pruritus therapy – What is established, what is confirmed, what is new? J Dtsch Dermatol Ges 11: 1049-1055. google scholar
  • Staubach P, Weisshaar E (2016). Magistralrezepturen zur topischen Therapie des Pruritus. Hautarzt 67: 635-639. google scholar
  • Tăerel AE, Soroceanu V, Rais C, Stancu E (2014). Study Of Quality Standards Application In Bucharest Community Pharmacies. Farmacia 62: 1082-1088. google scholar
  • TEB-Türkiye Eczacılar Birliği, 22. Bölge Malatya Eczacılar odası. www.malatyaeczaciodasi.org.tr (accessed July 04, 2018). google scholar
  • Zaid AN, Al-Ramahi R, Shahed Q, Saleh B, Elaraj J (2012). Determinants and frequency of pharmaceutical compounding in pharmacy practice in Palestine. Int J Pharm Pract 20: 9-14. google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Kolaç, T., Gürbüz, P., Yetiş, G., & Çırak, Z. (2019). Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey. İstanbul Journal of Pharmacy, 49(3), 125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012


AMA

Kolaç T, Gürbüz P, Yetiş G, Çırak Z. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey. İstanbul Journal of Pharmacy. 2019;49(3):125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012


ABNT

Kolaç, T.; Gürbüz, P.; Yetiş, G.; Çırak, Z. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey. İstanbul Journal of Pharmacy, [Publisher Location], v. 49, n. 3, p. 125-131, 2019.


Chicago: Author-Date Style

Kolaç, Turgay, and Perihan Gürbüz and Gülsüm Yetiş and Zehra Deniz Çırak. 2019. “Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey.” İstanbul Journal of Pharmacy 49, no. 3: 125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012


Chicago: Humanities Style

Kolaç, Turgay, and Perihan Gürbüz and Gülsüm Yetiş and Zehra Deniz Çırak. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey.” İstanbul Journal of Pharmacy 49, no. 3 (Jun. 2021): 125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012


Harvard: Australian Style

Kolaç, T & Gürbüz, P & Yetiş, G & Çırak, Z 2019, 'Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey', İstanbul Journal of Pharmacy, vol. 49, no. 3, pp. 125-131, viewed 25 Jun. 2021, https://doi.org/10.26650/IstanbulJPharm.2019.19012


Harvard: Author-Date Style

Kolaç, T. and Gürbüz, P. and Yetiş, G. and Çırak, Z. (2019) ‘Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey’, İstanbul Journal of Pharmacy, 49(3), pp. 125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012 (25 Jun. 2021).


MLA

Kolaç, Turgay, and Perihan Gürbüz and Gülsüm Yetiş and Zehra Deniz Çırak. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey.” İstanbul Journal of Pharmacy, vol. 49, no. 3, 2019, pp. 125-131. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2019.19012


Vancouver

Kolaç T, Gürbüz P, Yetiş G, Çırak Z. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey. İstanbul Journal of Pharmacy [Internet]. 25 Jun. 2021 [cited 25 Jun. 2021];49(3):125-131. Available from: https://doi.org/10.26650/IstanbulJPharm.2019.19012 doi: 10.26650/IstanbulJPharm.2019.19012


ISNAD

Kolaç, Turgay - Gürbüz, Perihan - Yetiş, Gülsüm - Çırak, Zehra Deniz. Determination of pharmacy pharmacists and pharmacy employees' knowledge of and attitudes towards magistral drug preparation in Malatya/ Turkey”. İstanbul Journal of Pharmacy 49/3 (Jun. 2021): 125-131. https://doi.org/10.26650/IstanbulJPharm.2019.19012



TIMELINE


Accepted06.03.2019

LICENCE


Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.