Research Article


DOI :10.26650/IstanbulJPharm.2019.19022   IUP :10.26650/IstanbulJPharm.2019.19022    Full Text (PDF)

Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones

Gökçe Cihan ÜstündağEmel Mataracı KaraGültaze Çapan

A novel series of benzoyl hydrazones (2a-j) were synthesized and evaluated, in vitro, for antimicrobial activity against selected bacteria and fungi. The structures of the compounds were established by IR, 1 H-NMR, 13C-NMR (APT), electrospray ionization mass spectrometry (ESI-MS) and microanalysis (C, H, N). All of the tested compounds, except for compound 2h, displayed weak antibacterial properties against Staphylococcus epidermidis ATCC 12228 and Staphylococcus aureus ATCC 29213. Compounds 2a, 2b, 2e, 2f and 2i further exhibited marginal antifungal activity against Candida parapsilosis.


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APA

Cihan Üstündağ, G., Mataracı Kara, E., & Çapan, G. (2019). Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones. İstanbul Journal of Pharmacy, 49(3), 142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022


AMA

Cihan Üstündağ G, Mataracı Kara E, Çapan G. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones. İstanbul Journal of Pharmacy. 2019;49(3):142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022


ABNT

Cihan Üstündağ, G.; Mataracı Kara, E.; Çapan, G. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones. İstanbul Journal of Pharmacy, [Publisher Location], v. 49, n. 3, p. 142-147, 2019.


Chicago: Author-Date Style

Cihan Üstündağ, Gökçe, and Emel Mataracı Kara and Gültaze Çapan. 2019. “Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones.” İstanbul Journal of Pharmacy 49, no. 3: 142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022


Chicago: Humanities Style

Cihan Üstündağ, Gökçe, and Emel Mataracı Kara and Gültaze Çapan. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones.” İstanbul Journal of Pharmacy 49, no. 3 (Sep. 2021): 142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022


Harvard: Australian Style

Cihan Üstündağ, G & Mataracı Kara, E & Çapan, G 2019, 'Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones', İstanbul Journal of Pharmacy, vol. 49, no. 3, pp. 142-147, viewed 23 Sep. 2021, https://doi.org/10.26650/IstanbulJPharm.2019.19022


Harvard: Author-Date Style

Cihan Üstündağ, G. and Mataracı Kara, E. and Çapan, G. (2019) ‘Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones’, İstanbul Journal of Pharmacy, 49(3), pp. 142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022 (23 Sep. 2021).


MLA

Cihan Üstündağ, Gökçe, and Emel Mataracı Kara and Gültaze Çapan. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones.” İstanbul Journal of Pharmacy, vol. 49, no. 3, 2019, pp. 142-147. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2019.19022


Vancouver

Cihan Üstündağ G, Mataracı Kara E, Çapan G. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones. İstanbul Journal of Pharmacy [Internet]. 23 Sep. 2021 [cited 23 Sep. 2021];49(3):142-147. Available from: https://doi.org/10.26650/IstanbulJPharm.2019.19022 doi: 10.26650/IstanbulJPharm.2019.19022


ISNAD

Cihan Üstündağ, Gökçe - Mataracı Kara, Emel - Çapan, Gültaze. Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones”. İstanbul Journal of Pharmacy 49/3 (Sep. 2021): 142-147. https://doi.org/10.26650/IstanbulJPharm.2019.19022



TIMELINE


Accepted18.09.2019

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