Meeting Abstract


DOI :10.26650/JARHS2021-1136772   IUP :10.26650/JARHS2021-1136772    Full Text (PDF)

CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS

Afet SattarovaMilad AsadiTayfun YoldaşOsman BozbıyıkAhmed Al OmarCan MüftüoğluUfuk MertAyşe Caner

Objective: Early and accurate diagnosis are key factors in the successful treatment of colorectal cancer (CRC). Therefore, the discovery of new, reliable, and non-invasive biomarkers in CRC patients is becoming an attractive topic in cancer research. Circular RNAs (circRNA) are RNAs that have high stability and can be tissue specific. In addition, expression levels can be detected in various non-invasive samples such as saliva and serum, due to these properties, they can be a biomarker for various cancer, can be substituted by invasive methods in CRC Methods: In this study, 25 circular RNAs in the literature related to CRC were evaluated for the first time in saliva samples. For this purpose, the expression level of 25 circular RNAs in saliva samples of 25 CRC patients was investigated by comparing them with 25 healthy control samples. Results: We found that the expression level of 9 circular RNAs varied significantly between the two groups. In addition, ROC curve analysis showed that hsa_circ_0078767 could potentially be a biomarker candidate in CRC diagnosis. Conclusion: The study showed the potential for circRNAs, particularly hsa_circ_0078767, to be a noninvasive biomarker in CRC, but further studies with more subjects are needed to confirm these results.


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    APA

    Sattarova, A., Asadi, M., Yoldaş, T., Bozbıyık, O., Al Omar, A., Müftüoğlu, C., Mert, U., & Caner, A. (2022). CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS. Journal of Advanced Research in Health Sciences, 5(1), 50-50. https://doi.org/10.26650/JARHS2021-1136772


    AMA

    Sattarova A, Asadi M, Yoldaş T, Bozbıyık O, Al Omar A, Müftüoğlu C, Mert U, Caner A. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS. Journal of Advanced Research in Health Sciences. 2022;5(1):50-50. https://doi.org/10.26650/JARHS2021-1136772


    ABNT

    Sattarova, A.; Asadi, M.; Yoldaş, T.; Bozbıyık, O.; Al Omar, A.; Müftüoğlu, C.; Mert, U.; Caner, A. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 50-50, 2022.


    Chicago: Author-Date Style

    Sattarova, Afet, and Milad Asadi and Tayfun Yoldaş and Osman Bozbıyık and Ahmed Al Omar and Can Müftüoğlu and Ufuk Mert and Ayşe Caner. 2022. “CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS.” Journal of Advanced Research in Health Sciences 5, no. 1: 50-50. https://doi.org/10.26650/JARHS2021-1136772


    Chicago: Humanities Style

    Sattarova, Afet, and Milad Asadi and Tayfun Yoldaş and Osman Bozbıyık and Ahmed Al Omar and Can Müftüoğlu and Ufuk Mert and Ayşe Caner. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 50-50. https://doi.org/10.26650/JARHS2021-1136772


    Harvard: Australian Style

    Sattarova, A & Asadi, M & Yoldaş, T & Bozbıyık, O & Al Omar, A & Müftüoğlu, C & Mert, U & Caner, A 2022, 'CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 50-50, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1136772


    Harvard: Author-Date Style

    Sattarova, A. and Asadi, M. and Yoldaş, T. and Bozbıyık, O. and Al Omar, A. and Müftüoğlu, C. and Mert, U. and Caner, A. (2022) ‘CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS’, Journal of Advanced Research in Health Sciences, 5(1), pp. 50-50. https://doi.org/10.26650/JARHS2021-1136772 (24 Feb. 2024).


    MLA

    Sattarova, Afet, and Milad Asadi and Tayfun Yoldaş and Osman Bozbıyık and Ahmed Al Omar and Can Müftüoğlu and Ufuk Mert and Ayşe Caner. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 50-50. [Database Container], https://doi.org/10.26650/JARHS2021-1136772


    Vancouver

    Sattarova A, Asadi M, Yoldaş T, Bozbıyık O, Al Omar A, Müftüoğlu C, Mert U, Caner A. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):50-50. Available from: https://doi.org/10.26650/JARHS2021-1136772 doi: 10.26650/JARHS2021-1136772


    ISNAD

    Sattarova, Afet - Asadi, Milad - Yoldaş, Tayfun - Bozbıyık, Osman - Al Omar, Ahmed - Müftüoğlu, Can - Mert, Ufuk - Caner, Ayşe. CircRNAs OF SALIVA AS POTENTIAL BIOMARKERS FOR COLORECTAL CANCER DIAGNOSIS”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 50-50. https://doi.org/10.26650/JARHS2021-1136772



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    Published Online09.08.2022

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