Meeting Abstract


DOI :10.26650/JARHS2021-1134054   IUP :10.26650/JARHS2021-1134054    Full Text (PDF)

LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA

Ayça CoşkunHamza Malik Okuyan

Osteosarcoma (OSA) is an aggressive bone tumor that occurs primarily in children and adolescents worldwide, with a high metastatic and recurrence ability. OSA is characterized by the transformation of mesenchymal cells and the formation of osteoid tissue. Although recent advancements have improved the current therapeutic management of OSA, the clinical outcomes of the disease still remain unsatisfactory. Therefore, it is important to determine the novel diagnostic markers and/or therapeutic targets for OSA. Autophagy is a highly conserved self-degradative process that plays a crucial role in various physiological mechanisms such as survival, homeostasis, development and differentiation. Dysfunction of autophagy is the relationship with the onset and development of several types of cancer, including OSA. Long non-coding ribonucleic acids (lncRNAs), a group of non-coding RNAs, regulate various pathophysiological mechanisms such as inflammation, autophagy and apoptosis. Recent studies investigating the role of lncRNAs in the pathogenesis of OSA have shown that these molecules might have diagnostic and therapeutic importance for the prevention of OSA. Here, we focus on lncRNAs that modulate autophagy in OSA and discuss the potential clinical values of lncRNAs for OSA. The current study contributes to a better understanding of OSA pathogenesis and to the development of novel therapeutic approaches for the prevention of OSA.


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    APA

    Coşkun, A., & Okuyan, H.M. (2022). LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA. Journal of Advanced Research in Health Sciences, 5(1), 48-48. https://doi.org/10.26650/JARHS2021-1134054


    AMA

    Coşkun A, Okuyan H M. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA. Journal of Advanced Research in Health Sciences. 2022;5(1):48-48. https://doi.org/10.26650/JARHS2021-1134054


    ABNT

    Coşkun, A.; Okuyan, H.M. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 48-48, 2022.


    Chicago: Author-Date Style

    Coşkun, Ayça, and Hamza Malik Okuyan. 2022. “LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA.” Journal of Advanced Research in Health Sciences 5, no. 1: 48-48. https://doi.org/10.26650/JARHS2021-1134054


    Chicago: Humanities Style

    Coşkun, Ayça, and Hamza Malik Okuyan. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 48-48. https://doi.org/10.26650/JARHS2021-1134054


    Harvard: Australian Style

    Coşkun, A & Okuyan, HM 2022, 'LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 48-48, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1134054


    Harvard: Author-Date Style

    Coşkun, A. and Okuyan, H.M. (2022) ‘LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA’, Journal of Advanced Research in Health Sciences, 5(1), pp. 48-48. https://doi.org/10.26650/JARHS2021-1134054 (24 Feb. 2024).


    MLA

    Coşkun, Ayça, and Hamza Malik Okuyan. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 48-48. [Database Container], https://doi.org/10.26650/JARHS2021-1134054


    Vancouver

    Coşkun A, Okuyan HM. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):48-48. Available from: https://doi.org/10.26650/JARHS2021-1134054 doi: 10.26650/JARHS2021-1134054


    ISNAD

    Coşkun, Ayça - Okuyan, HamzaMalik. LONG NON-CODING RNAs AND AUTOPHAGY IN OSTEOSARCOMA”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 48-48. https://doi.org/10.26650/JARHS2021-1134054



    TIMELINE


    Published Online09.08.2022

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