Meeting Abstract


DOI :10.26650/JARHS2021-1136829   IUP :10.26650/JARHS2021-1136829    Full Text (PDF)

miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA

Fatma Seher Pektopal DelekDemet Akdeniz ÖdemişÖzge Şükrüoğlu ErdoğanSeda Kılıç ErciyasBüşra KurtŞeref Buğra TunçerHülya Yazıcı

Ovarian cancer is a late-stage cancer with early and frequent recurrence, and there is still no effective treatment.There are no sensitive and specific biomarkers to be used effectively in the early diagnosis and treatment of the disease.Those currently used in the clinic are extremely insufficient for the early diagnosis and treatment follow-up of the disease, in terms of accurately determining the minimal residual disease.Many studies have shown that deregulation or dysfunction of miRNAs in the small non-coding RNA class contributes to cancer development However, it is known that the expressions of a number of miRNAs differ in ovarian cancer. Examining the expression patterns of known miRNAs in cancer research by comparing them between patients and healthy people is extremely important in terms of finding disease-specific biological markers, and determining the roles of these molecules in the pathogenesis of ovarian cancer is also significant.In the thesis study presented, the expression profile of miR-3653-3p was investigated in a control group consisting of 150 high-risk ovarian cancer patients and 100 healthy individuals, and both groups were compared with each other.It was found that the expression level of miR-3653-3p in the peripheral blood of ovarian cancer patients was 9.49 times higher than the control groups and the results were shown to be statistically significant(p = 0.00).In addition to these results, whether miR-3653-3p can be used as a non-invasive biomarker in peripheral blood for ovarian cancer was evaluated by ROC analysis and it was shown that the molecule in question was a statistically significant biomarker.


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    APA

    Pektopal Delek, F.S., Akdeniz Ödemiş, D., Şükrüoğlu Erdoğan, Ö., Kılıç Erciyas, S., Kurt, B., Tunçer, Ş.B., & Yazıcı, H. (2022). miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences, 5(1), 37-37. https://doi.org/10.26650/JARHS2021-1136829


    AMA

    Pektopal Delek F S, Akdeniz Ödemiş D, Şükrüoğlu Erdoğan Ö, Kılıç Erciyas S, Kurt B, Tunçer Ş B, Yazıcı H. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences. 2022;5(1):37-37. https://doi.org/10.26650/JARHS2021-1136829


    ABNT

    Pektopal Delek, F.S.; Akdeniz Ödemiş, D.; Şükrüoğlu Erdoğan, Ö.; Kılıç Erciyas, S.; Kurt, B.; Tunçer, Ş.B.; Yazıcı, H. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 37-37, 2022.


    Chicago: Author-Date Style

    Pektopal Delek, Fatma Seher, and Demet Akdeniz Ödemiş and Özge Şükrüoğlu Erdoğan and Seda Kılıç Erciyas and Büşra Kurt and Şeref Buğra Tunçer and Hülya Yazıcı. 2022. “miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences 5, no. 1: 37-37. https://doi.org/10.26650/JARHS2021-1136829


    Chicago: Humanities Style

    Pektopal Delek, Fatma Seher, and Demet Akdeniz Ödemiş and Özge Şükrüoğlu Erdoğan and Seda Kılıç Erciyas and Büşra Kurt and Şeref Buğra Tunçer and Hülya Yazıcı. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 37-37. https://doi.org/10.26650/JARHS2021-1136829


    Harvard: Australian Style

    Pektopal Delek, FS & Akdeniz Ödemiş, D & Şükrüoğlu Erdoğan, Ö & Kılıç Erciyas, S & Kurt, B & Tunçer, ŞB & Yazıcı, H 2022, 'miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 37-37, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1136829


    Harvard: Author-Date Style

    Pektopal Delek, F.S. and Akdeniz Ödemiş, D. and Şükrüoğlu Erdoğan, Ö. and Kılıç Erciyas, S. and Kurt, B. and Tunçer, Ş.B. and Yazıcı, H. (2022) ‘miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA’, Journal of Advanced Research in Health Sciences, 5(1), pp. 37-37. https://doi.org/10.26650/JARHS2021-1136829 (24 Feb. 2024).


    MLA

    Pektopal Delek, Fatma Seher, and Demet Akdeniz Ödemiş and Özge Şükrüoğlu Erdoğan and Seda Kılıç Erciyas and Büşra Kurt and Şeref Buğra Tunçer and Hülya Yazıcı. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 37-37. [Database Container], https://doi.org/10.26650/JARHS2021-1136829


    Vancouver

    Pektopal Delek FS, Akdeniz Ödemiş D, Şükrüoğlu Erdoğan Ö, Kılıç Erciyas S, Kurt B, Tunçer ŞB, Yazıcı H. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):37-37. Available from: https://doi.org/10.26650/JARHS2021-1136829 doi: 10.26650/JARHS2021-1136829


    ISNAD

    Pektopal Delek, FatmaSeher - Akdeniz Ödemiş, Demet - Şükrüoğlu Erdoğan, Özge - Kılıç Erciyas, Seda - Kurt, Büşra - Tunçer, ŞerefBuğra - Yazıcı, Hülya. miR-3653-3P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH OVARIAN CARCINOMA”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 37-37. https://doi.org/10.26650/JARHS2021-1136829



    TIMELINE


    Published Online09.08.2022

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