Meeting Abstract


DOI :10.26650/JARHS2021-1136692   IUP :10.26650/JARHS2021-1136692    Full Text (PDF)

TUMOR-ASSOCIATED MICROBIOME

Ayşe Caner

The human body is an intricate complex containing an estimated three trillion Mo members alongside its own cells and genes. Host-microbiome interactions in many parts of the body comprehensively govern multiple physiological processes and various multifactorial disease conditions. In the last decade, with advances in next-generation sequencing, the study of the human microbiome in oncology has become a rapidly developing and interesting field. It has been suggested that microbiome communities influence the development, progression, metastasis formation, and treatment response of multiple cancer types. Understanding the molecular mechanisms of such cancer-modulating interactions and the effects on cancer therapy is considered of great scientific and clinical importance. Although causal evidence of microbial effects on cancer biology is beginning to emerge and the microbiome can enable the development of new cancer-related diagnoses and treatments, little is still known. Microbes and microbiota contribute to carcinogenesis through multiple mechanisms. Specially, microbiome-cancer modulation is driven by a host-microbe interactions such as contact-dependent, contactindependent, and immunological mechanisms, by altering the balance of host cell proliferation and death, and influencing the immune system functions, the metabolism of host-produced factors, and the formation of microbial products. Beyond the gut, the tumor-associated microbial communities, located in the tumor, tumor microenvironment, and other part of the body, can interact with the tumor cells, immune cells, and tumor microenvironment, subsequently leading to cancer progression and treatment outcome. However, there is still a great need for standardization of the methodology and the quality control in microbiome studies, alongside further translational studies.


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    APA

    Caner, A. (2022). TUMOR-ASSOCIATED MICROBIOME. Journal of Advanced Research in Health Sciences, 5(1), 22-22. https://doi.org/10.26650/JARHS2021-1136692


    AMA

    Caner A. TUMOR-ASSOCIATED MICROBIOME. Journal of Advanced Research in Health Sciences. 2022;5(1):22-22. https://doi.org/10.26650/JARHS2021-1136692


    ABNT

    Caner, A. TUMOR-ASSOCIATED MICROBIOME. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 22-22, 2022.


    Chicago: Author-Date Style

    Caner, Ayşe,. 2022. “TUMOR-ASSOCIATED MICROBIOME.” Journal of Advanced Research in Health Sciences 5, no. 1: 22-22. https://doi.org/10.26650/JARHS2021-1136692


    Chicago: Humanities Style

    Caner, Ayşe,. TUMOR-ASSOCIATED MICROBIOME.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 22-22. https://doi.org/10.26650/JARHS2021-1136692


    Harvard: Australian Style

    Caner, A 2022, 'TUMOR-ASSOCIATED MICROBIOME', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 22-22, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1136692


    Harvard: Author-Date Style

    Caner, A. (2022) ‘TUMOR-ASSOCIATED MICROBIOME’, Journal of Advanced Research in Health Sciences, 5(1), pp. 22-22. https://doi.org/10.26650/JARHS2021-1136692 (24 Feb. 2024).


    MLA

    Caner, Ayşe,. TUMOR-ASSOCIATED MICROBIOME.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 22-22. [Database Container], https://doi.org/10.26650/JARHS2021-1136692


    Vancouver

    Caner A. TUMOR-ASSOCIATED MICROBIOME. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):22-22. Available from: https://doi.org/10.26650/JARHS2021-1136692 doi: 10.26650/JARHS2021-1136692


    ISNAD

    Caner, Ayşe. TUMOR-ASSOCIATED MICROBIOME”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 22-22. https://doi.org/10.26650/JARHS2021-1136692



    TIMELINE


    Published Online09.08.2022

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