Research Article


DOI :10.26650/jchild.2023.1059843   IUP :10.26650/jchild.2023.1059843    Full Text (PDF)

Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood

Asuman DemirbuğaSelda Hançerli TörünÖzge KabaSüheyla GümüşRaif YıldızMetin UysalolSevim MeşeMustafa ÖnelAli AğaçfidanAyper Somer

Objective: The COVID-19 pandemic and annual influenza epidemic are responsible for thousands of deaths globally. This study was conducted to identify epidemiological aspects while demonstrating features that distinguish between influenza infection and COVID-19 disease in terms of clinical manifestations, laboratory, and prevention.

Methods: The patients hospitalized with confirmed influenza between October 2009-May 2014 (n=344) and with confirmed COVID-19 between April 2020-June 2021 (n=251) were enrolled in this study.

Results: The age of the patients with influenza infection was statistically significantly younger than the patients with SARS-CoV-2 infection (mean age 6 ± 5.3 years versus 13.0 ± 5.3 years, p <0.001). Fever, cough, and myalgia were the more common symptoms of influenza (p< 0.001; p<0.001, p=0.02). It was found that in cases of COVID-19 (n=55/251, 21.9%), headache complaints were more common at admission. Lymphopenia (n=89/251 35.4%) in COVID-19 and CRP elevation detected in influenza cases (n=201/344 58.4%) were statistically significant (p=0.01/ p<0.001). The mean hospital stay was 6±5 days (1-90 days) in influenza and 1±4 (1-64 days) in COVID-19 (p< 0.001). The radiological investigations were less necessary in children with COVID19 because of the lower overall incidence of infected, symptomatic, and severe cases and the lower presence of cough and respiratory symptoms compared to adults.

Conclusions: As the clinical and epidemiological features of COVID-19 have many parallels with influenza, it is important to ensure optimal management of both respiratory diseases as we expect that co-circulation will continue. Clinical findings in children are not sufficient for a definitive diagnosis, so it should be supported by a viral diagnosis test.

DOI :10.26650/jchild.2023.1059843   IUP :10.26650/jchild.2023.1059843    Full Text (PDF)

Çocuklarda SARS-Cov-2 ve İnfluenza Enfeksiyonunda Semptomdan Tanıya Benzerlikler ve Farklılıklar

Asuman DemirbuğaSelda Hançerli TörünÖzge KabaSüheyla GümüşRaif YıldızMetin UysalolSevim MeşeMustafa ÖnelAli AğaçfidanAyper Somer

Amaç: Bu çalışmada, çocuklarda klinik bulgular, laboratuvar tanısı ve hastalığı önleme açısından influenza enfeksiyonu ve COVID-19 hastalığı arasında ayrım yapan özellikleri gösterirken epidemiyolojik verileri de gözden geçirmek ve sentezlemek amaçlanmıştır.

Yöntem: Bu çalışmaya Ekim 2009-Mayıs 2014 yılları arasında hastanede yatan doğrulanmış influenza enfeksiyonu olan (n: 344) ve Nisan 2020-Haziran 2021 tarihleri arasında doğrulanmış COVID-19 (n: 251) nedeniyle yatan hastalar dahil edilmiştir.

Bulgular: İnfluenza enfeksiyonu olanlarda yaş, SARS-CoV-2 enfeksiyonuna göre istatistiksel olarak anlamlı küçük saptandı (ort. yaş 6 ± 5.3/13.0 ± 5.3, p <0.001). Ateş, öksürük ve miyalji influenzada en sık semptomlardı (p<0.001; p<0.001, p=0.02). Baş ağrısı hastaneye başvuruda COVID-19 olgularında daha sık bulundu (n=55/251, 21.9%). COVID-19 da lenfopeni, influenza olgularında ise CRP yüksekliği istatistiksel olarak yüksek bulundu(p=0.01/p<0.001). Ortalama hastanede kalış süresi influenzada 6±5 gün (1-90), COVID-19’da 1±4 gün (1-64) bulundu (p<0.001). Erişkinlere kıyasla öksürük ve solunum şikayetlerinin daha az olması, semptomatik ve ciddi vakaların da daha az olması sebebiyle radyolojik görüntülemelere COVID-19 hastalarında daha az ihtiyaç duyulmuştur.

Sonuç: COVID-19’un klinik ve epidemiyolojik bulguları influenza ile paralellik göstermekle birlikte, her iki etkenin de dolaşımda devam edeceği düşünülürse her iki hastalığında optimal yönetimini sağlamak önemlidir. Ani başlayan ateş, öksürük, miyalji gibi bulgular influenza açısından uyarıcı olsa da tanı için yeterli olmadığından viral tanı testlerinin kullanımı önemlidir.


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APA

Demirbuğa, A., Hançerli Törün, S., Kaba, Ö., Gümüş, S., Yıldız, R., Uysalol, M., Meşe, S., Önel, M., Ağaçfidan, A., & Somer, A. (2023). Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood. Journal of Child, 23(3), 211-216. https://doi.org/10.26650/jchild.2023.1059843


AMA

Demirbuğa A, Hançerli Törün S, Kaba Ö, Gümüş S, Yıldız R, Uysalol M, Meşe S, Önel M, Ağaçfidan A, Somer A. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood. Journal of Child. 2023;23(3):211-216. https://doi.org/10.26650/jchild.2023.1059843


ABNT

Demirbuğa, A.; Hançerli Törün, S.; Kaba, Ö.; Gümüş, S.; Yıldız, R.; Uysalol, M.; Meşe, S.; Önel, M.; Ağaçfidan, A.; Somer, A. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood. Journal of Child, [Publisher Location], v. 23, n. 3, p. 211-216, 2023.


Chicago: Author-Date Style

Demirbuğa, Asuman, and Selda Hançerli Törün and Özge Kaba and Süheyla Gümüş and Raif Yıldız and Metin Uysalol and Sevim Meşe and Mustafa Önel and Ali Ağaçfidan and Ayper Somer. 2023. “Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood.” Journal of Child 23, no. 3: 211-216. https://doi.org/10.26650/jchild.2023.1059843


Chicago: Humanities Style

Demirbuğa, Asuman, and Selda Hançerli Törün and Özge Kaba and Süheyla Gümüş and Raif Yıldız and Metin Uysalol and Sevim Meşe and Mustafa Önel and Ali Ağaçfidan and Ayper Somer. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood.” Journal of Child 23, no. 3 (Mar. 2024): 211-216. https://doi.org/10.26650/jchild.2023.1059843


Harvard: Australian Style

Demirbuğa, A & Hançerli Törün, S & Kaba, Ö & Gümüş, S & Yıldız, R & Uysalol, M & Meşe, S & Önel, M & Ağaçfidan, A & Somer, A 2023, 'Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood', Journal of Child, vol. 23, no. 3, pp. 211-216, viewed 3 Mar. 2024, https://doi.org/10.26650/jchild.2023.1059843


Harvard: Author-Date Style

Demirbuğa, A. and Hançerli Törün, S. and Kaba, Ö. and Gümüş, S. and Yıldız, R. and Uysalol, M. and Meşe, S. and Önel, M. and Ağaçfidan, A. and Somer, A. (2023) ‘Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood’, Journal of Child, 23(3), pp. 211-216. https://doi.org/10.26650/jchild.2023.1059843 (3 Mar. 2024).


MLA

Demirbuğa, Asuman, and Selda Hançerli Törün and Özge Kaba and Süheyla Gümüş and Raif Yıldız and Metin Uysalol and Sevim Meşe and Mustafa Önel and Ali Ağaçfidan and Ayper Somer. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood.” Journal of Child, vol. 23, no. 3, 2023, pp. 211-216. [Database Container], https://doi.org/10.26650/jchild.2023.1059843


Vancouver

Demirbuğa A, Hançerli Törün S, Kaba Ö, Gümüş S, Yıldız R, Uysalol M, Meşe S, Önel M, Ağaçfidan A, Somer A. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood. Journal of Child [Internet]. 3 Mar. 2024 [cited 3 Mar. 2024];23(3):211-216. Available from: https://doi.org/10.26650/jchild.2023.1059843 doi: 10.26650/jchild.2023.1059843


ISNAD

Demirbuğa, Asuman - Hançerli Törün, Selda - Kaba, Özge - Gümüş, Süheyla - Yıldız, Raif - Uysalol, Metin - Meşe, Sevim - Önel, Mustafa - Ağaçfidan, Ali - Somer, Ayper. Similarities and Differences Between SARS-Cov-2 and Influenza Infection from Symptom to Diagnosis in Childhood”. Journal of Child 23/3 (Mar. 2024): 211-216. https://doi.org/10.26650/jchild.2023.1059843



TIMELINE


Submitted18.01.2023
Accepted15.03.2023
Published Online05.09.2023

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