Research Article


DOI :10.26650/jchild.2021.1.868115   IUP :10.26650/jchild.2021.1.868115    Full Text (PDF)

Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns

Muhammet BulutDilek Küçük AlemdarKıvanç ÇelikkalkanEmine TekinÖzge ErenHandan Ayhan AkoğluAzime Bulutİlknur Okur AkşanSeyyit Bahaettin Öncü

Objective: We aimed to consider Galen vein aneurysm(GVA) in cases that may often get a diagnosis later due to the pre-diagnoses of transient tachypnea of newborn and congenital heart disease accompanied by moderate-severe pulmonary hypertension in the postpartum period. 

Method: The study included cases that were followed and treated with the diagnosis of GVA in our clinic between 2016-2020. Types of delivery, week of delivery, birthweight/height/head circumference, medical treatments, and imagings were recorded from patient files. The risk evaluation was performed according to Bicetre and the scoring was recorded. 

Results: Of our cases; 80% (n=4) were female, and 80% (n=4) had been delivered via spontaneous vaginally. Their week of delivery was 39.20±.83 (min:38, max:40), birth weight was 3488±415 gr, head circumference was 36.20±1.30 and height was 51.20±1.30 cm. Firstly, all cases had tachypnea, dyspnea, cyanosis, and tachycardia. Of our cases, three were intubated, others (4.5) received non-invasive support only. The patient (infant 3) with a lower Bicetre score did not stabilize and died. One of our cases (infant 4) whose Bicetre score was above 12, was operated electively. In all cases the GVA was accompanied by persistent pulmonary hypertension (PPHT). The cases that had severe PPHT and did not improve despite inotrop treatment died. 

Conclusion: Galen vein aneurysms should certainly be considered in PPHT cases in the early stage of those that don’t respond to multiple treatment options.

DOI :10.26650/jchild.2021.1.868115   IUP :10.26650/jchild.2021.1.868115    Full Text (PDF)

Yenidoğanda Pulmoner Hipertansiyon ve Galen Ven Anevrizması Birlikteliği

Muhammet BulutDilek Küçük AlemdarKıvanç ÇelikkalkanEmine TekinÖzge ErenHandan Ayhan AkoğluAzime Bulutİlknur Okur AkşanSeyyit Bahaettin Öncü

Amaç: Doğum sonrası süreçte sıklıkla yenidoğan geçici taşipnesi ve konjenital kalp hastalığı ön tanıları nedeniyle geç tanı alabilen ve orta-ağır pulmoner hipertansiyonun eşlik ettiği vakalarda Galen ven anevrizması (GVA) riskine dikkat çekmeyi amaçladık. 

Yöntem: GVA tanısıyla merkezimizde takip ve tedavisi yapılan vakalar çalışmaya alındı. Vakaların doğum şekli, doğum haftası, doğum boy-kilo-baş çevresi, yapılan medikal tedaviler ve görüntülemeler hasta dosyasından kaydedildi. Bicetre skoruna göre yapılan risk değerlendirmesi kaydedildi. 

Bulgular: Vakalarımızın %80’i kız (n=4) olup, %80’i (n=4) spontan vajinal yol ile doğurtuldu. Doğum haftaları 39,20±0,83 (min:38, max:40) hafta, ağırlıkları 3488±415 (min:2820, max:3800) gr, baş çevreleri 36,20±1,30 (min:34, max:37) cm, doğum boyları 51,20±1,30 (min:50, max:52) cm idi. Vakalarımızın tümünün ilk fizik muayenesinde taşipne, inlemeli solunum, siyanoz ve taşikardi mevcut idi. Vakalarımızdan 3’ü entübe edilerek mekanik ventilatör desteği başlanan hastalar olup, 2 tanesi (bebek 4,5) sadece non-invaziv destek aldı. Bicetre skoru düşük olan hasta (bebek 3) erken dönemde tüm tedavilere rağmen stabilleşmedi ve eksitus oldu. Bicetre skoru 12’nin üzerinde olan vakalarımızdan birine (bebek 4) elektif şartlarda cerrahi uygulandı. Tüm vakalarımızda Galen ven anevrizmasına persistan pulmoner hipertansiyon (PPHT) eşlik etti. Vakalarımızdan ikisinde (bebek4-5) hafif-orta, diğer vakalarımızda ağır PHT gelişti. Ağır PPHT’u olan ve inotrop tedaviye rağmen düzelmeyen ve klinik olarak stabilleşmeyen vakalarımız (bebek 1-2) eksitus oldu.

Sonuç: Medikal tedaviye rağmen düzelmeyen PPHT vakalarında çoklu tedavi seçeneklerine başvurmadan, erken aşamada GVA mutlaka akılda tutulmalıdır.



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APA

Bulut, M., Küçük Alemdar, D., Çelikkalkan, K., Tekin, E., Eren, Ö., Ayhan Akoğlu, H., Bulut, A., Okur Akşan, İ., & Öncü, S. (2021). Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns. Journal of Child, 21(1), 26-33. https://doi.org/10.26650/jchild.2021.1.868115


AMA

Bulut M, Küçük Alemdar D, Çelikkalkan K, Tekin E, Eren Ö, Ayhan Akoğlu H, Bulut A, Okur Akşan İ, Öncü S. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns. Journal of Child. 2021;21(1):26-33. https://doi.org/10.26650/jchild.2021.1.868115


ABNT

Bulut, M.; Küçük Alemdar, D.; Çelikkalkan, K.; Tekin, E.; Eren, Ö.; Ayhan Akoğlu, H.; Bulut, A.; Okur Akşan, İ.; Öncü, S. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns. Journal of Child, [Publisher Location], v. 21, n. 1, p. 26-33, 2021.


Chicago: Author-Date Style

Bulut, Muhammet, and Dilek Küçük Alemdar and Kıvanç Çelikkalkan and Emine Tekin and Özge Eren and Handan Ayhan Akoğlu and Azime Bulut and İlknur Okur Akşan and Seyyit Bahaettin Öncü. 2021. “Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns.” Journal of Child 21, no. 1: 26-33. https://doi.org/10.26650/jchild.2021.1.868115


Chicago: Humanities Style

Bulut, Muhammet, and Dilek Küçük Alemdar and Kıvanç Çelikkalkan and Emine Tekin and Özge Eren and Handan Ayhan Akoğlu and Azime Bulut and İlknur Okur Akşan and Seyyit Bahaettin Öncü. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns.” Journal of Child 21, no. 1 (Jul. 2021): 26-33. https://doi.org/10.26650/jchild.2021.1.868115


Harvard: Australian Style

Bulut, M & Küçük Alemdar, D & Çelikkalkan, K & Tekin, E & Eren, Ö & Ayhan Akoğlu, H & Bulut, A & Okur Akşan, İ & Öncü, S 2021, 'Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns', Journal of Child, vol. 21, no. 1, pp. 26-33, viewed 25 Jul. 2021, https://doi.org/10.26650/jchild.2021.1.868115


Harvard: Author-Date Style

Bulut, M. and Küçük Alemdar, D. and Çelikkalkan, K. and Tekin, E. and Eren, Ö. and Ayhan Akoğlu, H. and Bulut, A. and Okur Akşan, İ. and Öncü, S. (2021) ‘Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns’, Journal of Child, 21(1), pp. 26-33. https://doi.org/10.26650/jchild.2021.1.868115 (25 Jul. 2021).


MLA

Bulut, Muhammet, and Dilek Küçük Alemdar and Kıvanç Çelikkalkan and Emine Tekin and Özge Eren and Handan Ayhan Akoğlu and Azime Bulut and İlknur Okur Akşan and Seyyit Bahaettin Öncü. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns.” Journal of Child, vol. 21, no. 1, 2021, pp. 26-33. [Database Container], https://doi.org/10.26650/jchild.2021.1.868115


Vancouver

Bulut M, Küçük Alemdar D, Çelikkalkan K, Tekin E, Eren Ö, Ayhan Akoğlu H, Bulut A, Okur Akşan İ, Öncü S. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns. Journal of Child [Internet]. 25 Jul. 2021 [cited 25 Jul. 2021];21(1):26-33. Available from: https://doi.org/10.26650/jchild.2021.1.868115 doi: 10.26650/jchild.2021.1.868115


ISNAD

Bulut, Muhammet - Küçük Alemdar, Dilek - Çelikkalkan, Kıvanç - Tekin, Emine - Eren, Özge - Ayhan Akoğlu, Handan - Bulut, Azime - Okur Akşan, İlknur - Öncü, Seyyit Bahaettin. Coexistence of Pulmonary Hypertension and Galen Vein Aneurysm in Newborns”. Journal of Child 21/1 (Jul. 2021): 26-33. https://doi.org/10.26650/jchild.2021.1.868115



TIMELINE


Submitted26.01.2020
First Revision10.02.2021
Last Revision12.02.2021
Accepted20.02.2021
Published Online02.04.2021

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