Research Article


DOI :10.26650/IUITFD.1467973   IUP :10.26650/IUITFD.1467973    Full Text (PDF)

RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS

Dicle Yaşar AksöylerMehmet Can NergizoğullarıYiğit YalçınErol KozanoğluBora Edim AkalınLeman Damla ErcanCemil Burak KulleÖzlem PolatMüşerref Beril DinçerYağmur MinareciCemalettin ErtekinRıfat Atilla Arıncı

Objective:  Abdominoperineal resection and pelvic exenteration for the surgical treatment of advanced colorectal or gynaecological cancers can result in large perineal defects and severe surgical site morbidity. Several regional flaps can be used to treat radiation- and extirpative surgery-related wound breakdowns. This study aims to retrospectively evaluate the efficiency of different flaps used in the reconstruction of perineal defects.

Material and Method: A retrospective review of pelvic reconstructions performed between May 2021 and August 2023 was conducted, with a 6-month follow-up. Ten patients who underwent abdominoperineal resection with immediate abdominal-based flap (n=4) or thigh-based flap (n=6) reconstruction of the perineal/pelvic defect were evaluated. The two groups were compared in terms of patient characteristics, aetiology, preferred treatment, and postoperative complications.

Result: Five women and five men underwent comprehensive pelvic reconstruction. The mean age was 49.6 years (range 26–76) and mean BMI of 28.6 kg/m2 (range 21.3–50). Five patients had previously undergone radiotherapy. In total, 11 flaps were created based on the type of perineal defect. One patient experienced a minor dehiscence (<5 cm). Two patients experienced major dehiscence (>5 cm), and required reoperation. A patient with Crohn’s disease developed one intra-abdominal abscess because of spontaneous fistula formation. There was no vascular compromise in the flaps.

Conclusion: Repair options vary depending on the nature of the defect and extent of resection. The primary goals of reconstruction are to eliminate pelvic dead space and separate the intra-abdominal content from the perineum to prevent herniation and strangulation of the small intestines and to ensure that the perineal wound heals without complications.

DOI :10.26650/IUITFD.1467973   IUP :10.26650/IUITFD.1467973    Full Text (PDF)

ZORLAYICI PERİNE DEFEKTLERİNDE ONARIM SEÇENEKLERİ

Dicle Yaşar AksöylerMehmet Can NergizoğullarıYiğit YalçınErol KozanoğluBora Edim AkalınLeman Damla ErcanCemil Burak KulleÖzlem PolatMüşerref Beril DinçerYağmur MinareciCemalettin ErtekinRıfat Atilla Arıncı

Amaç: İleri evre kolorektal veya jinekolojik kanserlerin cerrahi tedavisinde abdominoperineal rezeksiyon ve pelvik ekzenterasyon ameliyatları büyük perineal defektlere ve ciddi cerrahi alan morbiditesine neden olabilir. Radyasyon ve onkolojik cerrahiye bağlı yara iyileşme problemlerini engellemek için çeşitli bölgesel flepler yara kapatılmasında kullanılabilir.

Gereç ve Yöntem: Mayıs 2021 ile Ağustos 2023 arasında gerçekleştirilen pelvik rekonstrüksiyon vakaları geriye dönük olarak altı aylık takip süresi ile incelendi. Toplamda 10 hasta çalışmaya dahil edildi. Bu hastalara karın temelli flepler (n=4) ve uyluk temelli flepler (n=6) kullanılarak perineal defekt rekonstrüksiyonu gerçekleştirildi. Bu iki hasta grubu hastaların demografik özellikleri, etiyoloji, tercih edilen tedavi yöntemi ve ameliyat sonrası gelişen komplikasyonlar açısından karşılaştırıldı.

Bulgular: Beş kadın ve beş erkeğe kapsamlı pelvik rekonstrüksiyon uygulandı; yaş ortalaması 49,6 (26-76 aralığı) ve ortalama vücut kitle indeksi (VKI) 28,6 kg/m2 (21,3-50 aralığı) idi. Beş hastaya daha önce radyoterapi uygulanmıştı. Perine defektinin tipine göre toplam 11 flep uygulandı. Bir hastada yara yerinde küçük bir ayrılma (<5 cm) oldu. İki hastada yara yerinde büyük açılma oldu (>5 cm) ve yeniden ameliyat edilmeleri gerekti. Crohn hastalığı olan hastada spontan fistül oluşumu sonucu karın içi abse gelişti. Fleplerde kısmi veya tam kayıp izlenmedi.

Sonuç: Onarım seçenekleri defektin boyutuna ve rezeksiyonun derecesine bağlı olarak değişmektedir. Rekonstrüksiyonda öncelikli amaç pelvik ölü boşluğu ortadan kaldırmak ile karın içi içeriğin perineden ayrılmasını sağlamak, ince bağırsakların fıtıklaşmasını önlemek ve komplikasyonsuz yara iyileşmesini sağlamaktır.


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APA

Aksöyler, D.Y., Nergizoğulları, M.C., Yalçın, Y., Kozanoğlu, E., Akalın, B.E., Ercan, L.D., Kulle, C., Polat, Ö., Dinçer, M.B., Minareci, Y., Ertekin, C., & Arıncı, R.A. (2024). RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS. Journal of Istanbul Faculty of Medicine, 87(4), 275-282. https://doi.org/10.26650/IUITFD.1467973


AMA

Aksöyler D Y, Nergizoğulları M C, Yalçın Y, Kozanoğlu E, Akalın B E, Ercan L D, Kulle C, Polat Ö, Dinçer M B, Minareci Y, Ertekin C, Arıncı R A. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS. Journal of Istanbul Faculty of Medicine. 2024;87(4):275-282. https://doi.org/10.26650/IUITFD.1467973


ABNT

Aksöyler, D.Y.; Nergizoğulları, M.C.; Yalçın, Y.; Kozanoğlu, E.; Akalın, B.E.; Ercan, L.D.; Kulle, C.; Polat, Ö.; Dinçer, M.B.; Minareci, Y.; Ertekin, C.; Arıncı, R.A. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 87, n. 4, p. 275-282, 2024.


Chicago: Author-Date Style

Aksöyler, Dicle Yaşar, and Mehmet Can Nergizoğulları and Yiğit Yalçın and Erol Kozanoğlu and Bora Edim Akalın and Leman Damla Ercan and Cemil Burak Kulle and Özlem Polat and Müşerref Beril Dinçer and Yağmur Minareci and Cemalettin Ertekin and Rıfat Atilla Arıncı. 2024. “RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS.” Journal of Istanbul Faculty of Medicine 87, no. 4: 275-282. https://doi.org/10.26650/IUITFD.1467973


Chicago: Humanities Style

Aksöyler, Dicle Yaşar, and Mehmet Can Nergizoğulları and Yiğit Yalçın and Erol Kozanoğlu and Bora Edim Akalın and Leman Damla Ercan and Cemil Burak Kulle and Özlem Polat and Müşerref Beril Dinçer and Yağmur Minareci and Cemalettin Ertekin and Rıfat Atilla Arıncı. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS.” Journal of Istanbul Faculty of Medicine 87, no. 4 (Nov. 2024): 275-282. https://doi.org/10.26650/IUITFD.1467973


Harvard: Australian Style

Aksöyler, DY & Nergizoğulları, MC & Yalçın, Y & Kozanoğlu, E & Akalın, BE & Ercan, LD & Kulle, C & Polat, Ö & Dinçer, MB & Minareci, Y & Ertekin, C & Arıncı, RA 2024, 'RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS', Journal of Istanbul Faculty of Medicine, vol. 87, no. 4, pp. 275-282, viewed 2 Nov. 2024, https://doi.org/10.26650/IUITFD.1467973


Harvard: Author-Date Style

Aksöyler, D.Y. and Nergizoğulları, M.C. and Yalçın, Y. and Kozanoğlu, E. and Akalın, B.E. and Ercan, L.D. and Kulle, C. and Polat, Ö. and Dinçer, M.B. and Minareci, Y. and Ertekin, C. and Arıncı, R.A. (2024) ‘RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS’, Journal of Istanbul Faculty of Medicine, 87(4), pp. 275-282. https://doi.org/10.26650/IUITFD.1467973 (2 Nov. 2024).


MLA

Aksöyler, Dicle Yaşar, and Mehmet Can Nergizoğulları and Yiğit Yalçın and Erol Kozanoğlu and Bora Edim Akalın and Leman Damla Ercan and Cemil Burak Kulle and Özlem Polat and Müşerref Beril Dinçer and Yağmur Minareci and Cemalettin Ertekin and Rıfat Atilla Arıncı. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS.” Journal of Istanbul Faculty of Medicine, vol. 87, no. 4, 2024, pp. 275-282. [Database Container], https://doi.org/10.26650/IUITFD.1467973


Vancouver

Aksöyler DY, Nergizoğulları MC, Yalçın Y, Kozanoğlu E, Akalın BE, Ercan LD, Kulle C, Polat Ö, Dinçer MB, Minareci Y, Ertekin C, Arıncı RA. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS. Journal of Istanbul Faculty of Medicine [Internet]. 2 Nov. 2024 [cited 2 Nov. 2024];87(4):275-282. Available from: https://doi.org/10.26650/IUITFD.1467973 doi: 10.26650/IUITFD.1467973


ISNAD

Aksöyler, DicleYaşar - Nergizoğulları, MehmetCan - Yalçın, Yiğit - Kozanoğlu, Erol - Akalın, BoraEdim - Ercan, LemanDamla - Kulle, Cemil Burak - Polat, Özlem - Dinçer, MüşerrefBeril - Minareci, Yağmur - Ertekin, Cemalettin - Arıncı, RıfatAtilla. RECONSTRUCTION OPTIONS FOR CHALLENGING PERINEAL DEFECTS”. Journal of Istanbul Faculty of Medicine 87/4 (Nov. 2024): 275-282. https://doi.org/10.26650/IUITFD.1467973



TIMELINE


Submitted14.04.2024
Accepted03.07.2024
Published Online25.09.2024

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