Review Article

DOI :10.26650/Tr-ENT.2023.1425530   IUP :10.26650/Tr-ENT.2023.1425530    Full Text (PDF)

Hospital Infections and Microbiota

Songül Türk AydınZerrin Aktaş

The human body hosts complex communities of microorganisms, collectively known as the “microbiota,” predominantly in the lower intestine. This microbiota, which consists of bacteria, viruses, and fungi, plays a vital role in the breakdown of various nutrients and maintenance of homeostasis. The microbiome, which represents the collective genetic content of these microorganisms, is intricately associated with human health and disease. Healthcare-associated infections (HCAIs), a major public health problem, contribute to high morbidity and mortality. Exposure to antibiotics, a primary risk factor for diseases, disrupts the microbiota and compromises its protective role. Age-related changes in the microbiota affect the onset and progression of various diseases by affecting the functional capacity and fitness of the host. Inanimate surfaces in built environments contribute to HCAIs by serving as potential reservoirs for microorganisms. Promising results have been observed with fecal microbiota transplantation (FMT) for treating Clostridium difficile infection, which is often associated with healthcare facilities. FMT prevents disease recurrence by restoring a healthy colonic microbiota and breaking the dysbiotic cycle. Furthermore, microbiota-based interventions have the potential to control emerging multidrug-resistant pathogens such as vancomycin-resistant enterococci and carbapenem-resistant Enterobacteriaceae.

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Türk Aydın, S., & Aktaş, Z. (2024). Hospital Infections and Microbiota. The Turkish Journal of Ear Nose and Throat, 34(1), 27-31.


Türk Aydın S, Aktaş Z. Hospital Infections and Microbiota. The Turkish Journal of Ear Nose and Throat. 2024;34(1):27-31.


Türk Aydın, S.; Aktaş, Z. Hospital Infections and Microbiota. The Turkish Journal of Ear Nose and Throat, [Publisher Location], v. 34, n. 1, p. 27-31, 2024.

Chicago: Author-Date Style

Türk Aydın, Songül, and Zerrin Aktaş. 2024. “Hospital Infections and Microbiota.” The Turkish Journal of Ear Nose and Throat 34, no. 1: 27-31.

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Türk Aydın, Songül, and Zerrin Aktaş. Hospital Infections and Microbiota.” The Turkish Journal of Ear Nose and Throat 34, no. 1 (Apr. 2024): 27-31.

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Türk Aydın, S & Aktaş, Z 2024, 'Hospital Infections and Microbiota', The Turkish Journal of Ear Nose and Throat, vol. 34, no. 1, pp. 27-31, viewed 23 Apr. 2024,

Harvard: Author-Date Style

Türk Aydın, S. and Aktaş, Z. (2024) ‘Hospital Infections and Microbiota’, The Turkish Journal of Ear Nose and Throat, 34(1), pp. 27-31. (23 Apr. 2024).


Türk Aydın, Songül, and Zerrin Aktaş. Hospital Infections and Microbiota.” The Turkish Journal of Ear Nose and Throat, vol. 34, no. 1, 2024, pp. 27-31. [Database Container],


Türk Aydın S, Aktaş Z. Hospital Infections and Microbiota. The Turkish Journal of Ear Nose and Throat [Internet]. 23 Apr. 2024 [cited 23 Apr. 2024];34(1):27-31. Available from: doi: 10.26650/Tr-ENT.2023.1425530


Türk Aydın, Songül - Aktaş, Zerrin. Hospital Infections and Microbiota”. The Turkish Journal of Ear Nose and Throat 34/1 (Apr. 2024): 27-31.


Published Online22.03.2024


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