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DOI :10.26650/experimed.1148905   IUP :10.26650/experimed.1148905    Tam Metin (PDF)

Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages

Dilşan Fulya KızılgedikArmağan CanerÇağlar YıldızBuğra OkasoğluSema Mısırİlhan YaylımSemra DemokanCeylan Hepokur

Objective: Endometriosis is a gynecological disease associated with chronic pelvic inflammation, pain, and infertility. Galectin-3 (Gal-3) is a protein that can bind to β-galactosides, which plays an important role in different biological processes according to the stages of the disease in patients with endometriosis. This study aimed to elucidate the importance of Gal-3 in endometriosis, to reveal its potential power as a non-invasive diagnostic biomarker in disease etiopathogenesis. Materials and Methods: The serum concentration of Gal-3 and cancer antigen 125 (CA-125) from whole blood were measured using enzyme-linked immuno sorbent assay (ELISA) and an auto-analyzer, respectively. Gal-3 expression was determined by quantitative real-time polymerase chain reaction (qRT-PCR) from peripheral blood. Results: We found significant differences for Gal-3 expression levels between the endometriosis and control groups (p <0.05). Gal-3 levels in the serum of women with endometriosis are also remarkably increased compared with the control group. Conclusion: Galectin-3 can play critical functions in the development and progression of endometriosis, so, further studies are needed in this area.

Anahtar Kelimeler: Galectin-3endometriosisbiomarkersqRT-PCR

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APA

Kızılgedik, D.F., Caner, A., Yıldız, Ç., Okasoğlu, B., Mısır, S., Yaylım, İ., Demokan, S., & Hepokur, C. (2023). Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages. Experimed, 13(1), 15-20. https://doi.org/10.26650/experimed.1148905


AMA

Kızılgedik D F, Caner A, Yıldız Ç, Okasoğlu B, Mısır S, Yaylım İ, Demokan S, Hepokur C. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages. Experimed. 2023;13(1):15-20. https://doi.org/10.26650/experimed.1148905


ABNT

Kızılgedik, D.F.; Caner, A.; Yıldız, Ç.; Okasoğlu, B.; Mısır, S.; Yaylım, İ.; Demokan, S.; Hepokur, C. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages. Experimed, [Publisher Location], v. 13, n. 1, p. 15-20, 2023.


Chicago: Author-Date Style

Kızılgedik, Dilşan Fulya, and Armağan Caner and Çağlar Yıldız and Buğra Okasoğlu and Sema Mısır and İlhan Yaylım and Semra Demokan and Ceylan Hepokur. 2023. “Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages.” Experimed 13, no. 1: 15-20. https://doi.org/10.26650/experimed.1148905


Chicago: Humanities Style

Kızılgedik, Dilşan Fulya, and Armağan Caner and Çağlar Yıldız and Buğra Okasoğlu and Sema Mısır and İlhan Yaylım and Semra Demokan and Ceylan Hepokur. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages.” Experimed 13, no. 1 (Jul. 2024): 15-20. https://doi.org/10.26650/experimed.1148905


Harvard: Australian Style

Kızılgedik, DF & Caner, A & Yıldız, Ç & Okasoğlu, B & Mısır, S & Yaylım, İ & Demokan, S & Hepokur, C 2023, 'Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages', Experimed, vol. 13, no. 1, pp. 15-20, viewed 13 Jul. 2024, https://doi.org/10.26650/experimed.1148905


Harvard: Author-Date Style

Kızılgedik, D.F. and Caner, A. and Yıldız, Ç. and Okasoğlu, B. and Mısır, S. and Yaylım, İ. and Demokan, S. and Hepokur, C. (2023) ‘Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages’, Experimed, 13(1), pp. 15-20. https://doi.org/10.26650/experimed.1148905 (13 Jul. 2024).


MLA

Kızılgedik, Dilşan Fulya, and Armağan Caner and Çağlar Yıldız and Buğra Okasoğlu and Sema Mısır and İlhan Yaylım and Semra Demokan and Ceylan Hepokur. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages.” Experimed, vol. 13, no. 1, 2023, pp. 15-20. [Database Container], https://doi.org/10.26650/experimed.1148905


Vancouver

Kızılgedik DF, Caner A, Yıldız Ç, Okasoğlu B, Mısır S, Yaylım İ, Demokan S, Hepokur C. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages. Experimed [Internet]. 13 Jul. 2024 [cited 13 Jul. 2024];13(1):15-20. Available from: https://doi.org/10.26650/experimed.1148905 doi: 10.26650/experimed.1148905


ISNAD

Kızılgedik, DilşanFulya - Caner, Armağan - Yıldız, Çağlar - Okasoğlu, Buğra - Mısır, Sema - Yaylım, İlhan - Demokan, Semra - Hepokur, Ceylan. Investigation of Galectin-3 Levels of Endometriosis Patients According to Stages”. Experimed 13/1 (Jul. 2024): 15-20. https://doi.org/10.26650/experimed.1148905



ZAMAN ÇİZELGESİ


Gönderim17.08.2022
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