European Oral Research

SUBMITINFORMATION
EnglishTürkçe

Case Study


DOI :10.17096/jiufd.96279   IUP :10.17096/jiufd.96279    Full Text (PDF)

Melkersson-Rosenthal Sendromu: Olgu Sunumu

Adil Başman, Mustafa Gümüşok, Şerife Değerli, Mustafa Kaya, Meryem Toraman alkurt

Melkersson-Rosenthal Sendromu (MRS), tekrarlayan periferik fasiyal paralizi, tekrarlayan ya da kalıcı fasiyal ödem ve fissürlü dil triadı ile karakterize nadir görülen bir hastalıktır. Etyolojisi tam olarak bilinmemekle birlikte, enfeksiyonlar, genetik yatkınlık, immün yetmezlik, besin intoleransı ve stres faktörleri gibi faktörlerin etkili olabileceği düşünülmektedir. Klasik triad her zaman birlikte bulunmayabilir, bulgular farklı zamanlarda tek tek de ortaya çıkabilir. En sık görülen bulgu orofasiyal ödemdir. MRS tanısı klinik bulgularla konulur. Bu olgu bildirisinde, üst dudağında tekrarlayan, şişlik ile şikayeti ile kliniğimize başvuran, MRS’nin klasik tiradına sahip 39 yaşındaki erkek hastanın klinik bulguları ile birlikte teşhis ve tedavisi sunulmuştur.
Keywords: Melkersson-Rosenthal Sendromu, Orofasiyal ödem, fissürlü dil, steroid kullanımı
DOI :10.17096/jiufd.96279   IUP :10.17096/jiufd.96279    Full Text (PDF)

MELKERSSON-ROSENTHAL SYNDROME: A CASE REPORT

Adil Başman, Mustafa Gümüşok, Şerife Değerli, Mustafa Kaya, Meryem Toraman alkurt

Melkersson-Rosenthal Syndrome (MRS) is a rare disorder consisting of a triad of persistent or recurrent orofacial edema, relapsing facial paralysis and fissured tongue. It is rarely possible to observe all aspects of the classical triad at the same time, since these symptoms may appear in different times of life cycle. The most common symptom is orofacial edema. Although etiology of MRS is unclear, various factors such as infections, genetic predisposition, immune deficiency, food intolerance and stress have been held responsible. MRS is diagnosed based on clinical features. This case report describes a 39 years old male patient with recurrent swelling of the upper lip. Clinical examinations showed classical triad of MRS. The diagnosis and treatment procedures were presented with special emphasis to the clinical features of this rare condition.
Keywords: Melkersson-Rosenthal Syndrome, orofacial edema, fissured tongue, steroid use

PDF View

References

  • Ang KL, Jones NS. Melkersson-rosenthal syndrome. J Laryngol Otol 2002;116(5):386-388. google scholar
  • Dodi I, Verri R, Brevi B, Bonetti L, Balestrier A, Saracino A, Akamin R, Izzi GC, Vanelli M, Sesenna E. A monosymptomatic melkersson-rosenthal syndrome in an 8-year old boy. Acta Biomed 2006;77(1):20-23. google scholar
  • Pisanty S, Sharav Y. The melkersson-rosenthal syndrome. Oral Surg Oral Med Oral Pathol 1969;27(6):729-733. google scholar
  • Greene RM, Rogers RS, 3rd. Melkersson-rosenthal syndrome: A review of 36 patients. J Am Acad Dermatol 1989;21(6):1263-1270. google scholar
  • Sakuntabhai A, MacLeod RI, Lawrence CM. Intralesional steroid injection after nerve block anesthesia in the treatment of orofacial granulomatosis. Arch Dermatol 1993;129(4):477-480. google scholar
  • Shapiro M, Peters S, Spinelli HM. Melkersson-rosenthal syndrome in the periocular area: A review of the literature and case report. Ann Plast Surg 2003;50(6):644-648. google scholar
  • Apaydin R, Bilen N, Bayramgurler D, Efendi H, Vahaboglu H. Detection of mycobacterium tuberculosis DNA in a patient with melkersson-rosenthal syndrome using polymerase chain reaction. Br J Dermatol 2000;142(6):1251-1252. google scholar
  • Liu R, Yu S. Melkersson-rosenthal syndrome: A review of seven patients. J Clin Neurosci 2013;20(7):993-995. google scholar
  • Ziem PE, Pfrommer C, Goerdt S, Orfanos CE, Blume-Peytavi U. Melkersson-rosenthal syndrome in childhood: A challenge in differential diagnosis and treatment. Br J Dermatol 2000;143(4):860-863. google scholar
  • Balevi B. Melkersson-rosenthal syndrome: Review of the literature and case report of a 10-year misdiagnosis. Quintessence Int 1997;28(4):265-269. google scholar
  • Zimmer WM, Rogers RS, 3rd, Reeve CM, Sheridan PJ. Orofacial manifestations of melkersson-rosenthal syndrome. A study of 42 patients and review of 220 cases from the literature. Oral Surg Oral Med Oral Pathol 1992;74(5):610-619. google scholar
  • Levenson MJ, Ingerman M, Grimes C, Anand KV. Melkersson-rosenthal syndrome. Arch Otolaryngol 1984;110(8):540-542. google scholar
  • Wadlington WB, Riley HD, Jr., Lowbeer L. The melkersson-rosenthal syndrome. Pediatrics 1984;73(4):502-506. google scholar
  • Winnie R, DeLuke DM. Melkersson-rosenthal syndrome. Review of literature and case report. Int J Oral Maxillofac Surg 1992;21(2):115-117. google scholar
  • Kesler A, Vainstein G, Gadoth N. Melkersson-rosenthal syndrome treated by methylprednisolone. Neurology 1998;51(5):1440-1441. google scholar
  • Orlando MR, Atkins JS, Jr. Melkersson-rosenthal syndrome. Arch Otolaryngol Head Neck Surg 1990;116(6):728-729. google scholar
  • Vistnes LM, Kernahan DA. The melkersson-rosenthal syndrome. Plast Reconstr Surg 1971;48(2):126-132. google scholar
  • Alexander RW, James RB. Melkersson-rosenthal syndrome: Review of literature and report of case. J Oral Surg 1972;30(8):599-604. google scholar
  • Sciubba JJ, Said-Al-Naief N. Orofacial granulomatosis: Presentation, pathology and management of 13 cases. J Oral Pathol Med 2003;32(10):576-585. google scholar
  • Gerressen M, Ghassemi A, Stockbrink G, Riediger D, Zadeh MD. Melkersson-rosenthal syndrome: Case report of a 30-year misdiagnosis. J Oral Maxillofac Surg 2005;63(7):1035-1039. google scholar
  • Leao JC, Hodgson T, Scully C, Porter S. Review article: Orofacial granulomatosis. Aliment Pharmacol Ther 2004;20(10):1019-1027. google scholar
  • van der Waal RI, Schulten EA, van de Scheur MR, Wauters IM, Starink TM, van der Waal I. Cheilitis granulomatosa. J Eur Acad Dermatol Venereol 2001;15(6):519-523. google scholar
  • Dupuy A, Cosnes J, Revuz J, Delchier JC, Gendre JP, Cosnes A. Oral crohn disease: Clinical characteristics and long-term follow-up of 9 cases. Arch Dermatol 1999;135(4):439-442. google scholar
  • Kemal Ö, Özgürsoy OB , Dursun G, Tulunay Ö. Melkersson-rosenthal sendromu klinik ve patolojik bulgular ve tedavi yaklaşımları. Turkiye Klinikleri J Med Sci 2007;27(1):128-131. google scholar
  • Cerimele D, Serri F. Intralesional injection of triamcinolone in the treatment of cheilitis granulomatosa. Arch Dermatol 1965;92(6):695-696. google scholar
  • Krutchkoff D, James R. Cheilitis granulomatosa. Successful treatment with combined local triamcinolone injections and surgery. Arch Dermatol 1978;114(8):1203-1206. google scholar
  • Patel DK, Levin KH. Bell palsy: Clinical examination and management. Cleve Clin J Med 2015;82(7):419-426. google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Başman, A., Gümüşok, M., Değerli, Ş., Kaya, M., & Toraman alkurt, M. (2017). Melkersson-Rosenthal Sendromu: Olgu Sunumu. European Oral Research, 51(1), 42-45. https://doi.org/10.17096/jiufd.96279


AMA

Başman A, Gümüşok M, Değerli Ş, Kaya M, Toraman alkurt M. Melkersson-Rosenthal Sendromu: Olgu Sunumu. European Oral Research. 2017;51(1):42-45. https://doi.org/10.17096/jiufd.96279


ABNT

Başman, A.; Gümüşok, M.; Değerli, Ş.; Kaya, M.; Toraman alkurt, M. Melkersson-Rosenthal Sendromu: Olgu Sunumu. European Oral Research, [Publisher Location], v. 51, n. 1, p. 42-45, 2017.


Chicago: Author-Date Style

Başman, Adil, and Mustafa Gümüşok and Şerife Değerli and Mustafa Kaya and Meryem Toraman alkurt. 2017. “Melkersson-Rosenthal Sendromu: Olgu Sunumu.” European Oral Research 51, no. 1: 42-45. https://doi.org/10.17096/jiufd.96279


Chicago: Humanities Style

Başman, Adil, and Mustafa Gümüşok and Şerife Değerli and Mustafa Kaya and Meryem Toraman alkurt. “Melkersson-Rosenthal Sendromu: Olgu Sunumu.” European Oral Research 51, no. 1 (Dec. 2024): 42-45. https://doi.org/10.17096/jiufd.96279


Harvard: Australian Style

Başman, A & Gümüşok, M & Değerli, Ş & Kaya, M & Toraman alkurt, M 2017, 'Melkersson-Rosenthal Sendromu: Olgu Sunumu', European Oral Research, vol. 51, no. 1, pp. 42-45, viewed 22 Dec. 2024, https://doi.org/10.17096/jiufd.96279


Harvard: Author-Date Style

Başman, A. and Gümüşok, M. and Değerli, Ş. and Kaya, M. and Toraman alkurt, M. (2017) ‘Melkersson-Rosenthal Sendromu: Olgu Sunumu’, European Oral Research, 51(1), pp. 42-45. https://doi.org/10.17096/jiufd.96279 (22 Dec. 2024).


MLA

Başman, Adil, and Mustafa Gümüşok and Şerife Değerli and Mustafa Kaya and Meryem Toraman alkurt. “Melkersson-Rosenthal Sendromu: Olgu Sunumu.” European Oral Research, vol. 51, no. 1, 2017, pp. 42-45. [Database Container], https://doi.org/10.17096/jiufd.96279


Vancouver

Başman A, Gümüşok M, Değerli Ş, Kaya M, Toraman alkurt M. Melkersson-Rosenthal Sendromu: Olgu Sunumu. European Oral Research [Internet]. 22 Dec. 2024 [cited 22 Dec. 2024];51(1):42-45. Available from: https://doi.org/10.17096/jiufd.96279 doi: 10.17096/jiufd.96279


ISNAD

Başman, Adil - Gümüşok, Mustafa - Değerli, Şerife - Kaya, Mustafa - Toraman alkurt, Meryem. “Melkersson-Rosenthal Sendromu: Olgu Sunumu”. European Oral Research 51/1 (Dec. 2024): 42-45. https://doi.org/10.17096/jiufd.96279



TIMELINE


Accepted10.03.2016
Published Online02.01.2017

LICENCE


Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.