European Oral Research

SUBMITINFORMATION
EnglishTürkçe

Original Research


DOI :10.17096/jiufd.61637   IUP :10.17096/jiufd.61637    Full Text (PDF)

PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY

Ali Çekici, Ülkü Başer, Gülden Işık, Süleyman Engin Akhan, Halim İşsever, Utku Onan

Purpose: To evaluate the effect of hormone replacement therapy(HRT) on periodontal treatment outcomes ina group of postmenopausal women with periodontitis. Materials and Methods: 23 post-menopausalchronic periodontitis patients were included in this study. The test group(n=11) consisted of women who started HRT with this study and received conjugated estrogen and medroxyprogesteron. The control group(n=12) was women not taking any HRT or supplement therapy. Study groups received the same periodontal treatment. All subjects examiendby recording the following: plaque index (PI), sulcusbleeding index (SBI), periodontal pocket depth (PD)and relative attachment level (RAL) from 6 sites in each tooth. Measurements were recorded at the baseline, 1 month, 3 months, and 6 months following periodontal treatment. Serum estrogene level andbone mineral density was recorded at baselineand 6 months following periodontal treatment.Results: The GI change was greater in the control group. There wasn’t significant difference by means of PD, the attachment gain was significantly greater in the HRT receiving group. Conclusion: HRT seems to have a positive effect on periodontal treatment outcomes.

Keywords: Periodontitis, hormone replacement therapy, post menopausal, root planning
DOI :10.17096/jiufd.61637   IUP :10.17096/jiufd.61637    Full Text (PDF)

HORMON REPLASMAN TEDAVİSİ ALAN POSTMENOPOZAL DÖNEMDEKİ KADINLARDA PERİODONTAL TEDAVİNİN ETKİLERİ

Ali Çekici, Ülkü Başer, Gülden Işık, Süleyman Engin Akhan, Halim İşsever, Utku Onan

Amaç: Bu çalışmanın amacı periodontitisli postmenopozal kadınlarda postmenopozal hormon tedavisinin (PHT), periodontal başlangıç tedavisi sonuçları üzerindeki etkilerini incelemektir. Gereç ve Yöntem: 23 kronik periodontitisli daha önce hormon tedavisi görmemiş olan postmenopozal kadın çalışmaya dâhil edilmiştir. Deney grubuna(n=11) konjuge östrojen ve medroxyprogesteron kullandırılmış, kontrol grubuna(n=12) herhangi bir hormon tedavisi verilmemiştir. Çalışmadaki tüm bireyler bireylere aynı periodontal başlangıç tedavisi uygulanmıştır. Plak indeksi(PI), dişeti oluğu kanama indeksi (DOKİ), sondalanabilir cep derinliği (SD),rölatif ataşman düzeyi (RAD) ölçümleri başlangıçta,1., 3., ve 6. aylarda, serum östrojen düzeyi, sistemik kemik yoğunluğu ölçümleri başlangıçta ve 6. ayda gerçekleştirilmiştir. Bulgular: DOKİ, kontrol grubunda daha fazla değişim göstermiştir. SD açısından gruplar arasında fark yoktur. PHT kullanmakta olan kadınlarda klinik atasman kazanci daha fazla bulunmuştur. Sonuç: PHT kullanımının periodontal tedavi sonuclarina olumlu katkı sağladığı söylenebilir.

Keywords: Periodontitis, hormon replasman tedavisi, post menopozal, kök yüzeyi düzleştirme

PDF View

References

  • Paulander J, Axelsson P, Lindhe J. Association between level of education and oral health status in 35-, 50-, 65- and 75-year-olds. J Clin Periodontol 2003;30(8):697-704. google scholar
  • Mascarenhas P, Gapski R, Al-Shammari K, Wang HL. Influence of sex hormones on the periodontium. J Clin Periodontol 2003;30(8):671-681. google scholar
  • Reddy MS. Reaching a better understanding of non-oral disease and the implication of periodontal infections. Periodontol 2000 2007;44:(9-14). google scholar
  • Krejci CB, Bissada NF. Women's health issues and their relationship to periodontitis. J Am Dent Assoc 2002;133(3):323-329. google scholar
  • Geurs NC. Osteoporosis and periodontal disease. Periodontol 2000 2007;44(29-43). google scholar
  • Lerner UH. Inflammation-induced bone remodeling in periodontal disease and the influence of post-menopausal osteoporosis. J Dent Res 2006;85(7):596-607. google scholar
  • Wactawski-Wende J. Periodontal diseases and osteoporosis: Association and mechanisms. Ann Periodontol 2001;6(1):197-208. google scholar
  • Friedlander AH. The physiology, medical management and oral implications of menopause. J Am Dent Assoc 2002;133(1):73-81. google scholar
  • Caufriez A. Hormonal replacement therapy (hrt) in postmenopause: A reappraisal. Ann Endocrinol (Paris) 2007;68(4):241-250. google scholar
  • Harman SM. Estrogen replacement in menopausal women: Recent and current prospective studies, the whi and the keeps. Gend Med 2006;3(4):254-269. google scholar
  • Gambacciani M, Ciaponi M, Genazzani AR. The hrt misuse and osteoporosis epidemic: A possible future scenario. Climacteric 2007;10(4):273-275. google scholar
  • Payne JB, Zachs NR, Reinhardt RA, Nummikoski PV, Patil K. The association between estrogen status and alveolar bone density changes in postmenopausal women with a history of periodontitis. J Periodontol 1997;68(1):24-31. google scholar
  • Speroff L. FM. Clinical gynecologic endocrinology and infertility: Lippincott Williams & Wilkins; 2005. google scholar
  • Cauley JA, Robbins J, Chen Z, Cummings SR, Jackson RD, LaCroix AZ, LeBoff M, Lewis CE, McGowan J, Neuner J, Pettinger M, Stefanick ML, Wactawski-Wende J, Watts NB. Effects of estrogen plus progestin on risk of fracture and bone mineral density: The women's health initiative randomized trial. JAMA 2003;290(13):1729-1738. google scholar
  • U.S. Preventive Services Task Force. Hormone therapy for the prevention of chronic conditions in postmenopausal women: Recommendations from the U.S. Preventive services task force. Ann Intern Med 2005;142(10):855-860. google scholar
  • Reinhardt RA, Payne JB, Maze CA, Patil KD, Gallagher SJ, Mattson JS. Influence of estrogen and osteopenia/osteoporosis on clinical periodontitis in postmenopausal women. J Periodontol 1999;70(8):823-828. google scholar
  • Ronderos M, Jacobs DR, Himes JH, Pihlstrom BL. Associations of periodontal disease with femoral bone mineral density and estrogen replacement therapy: Cross-sectional evaluation of US adults from nhanes iii. J Clin Periodontol 2000;27(10):778-786. google scholar
  • Pizzo G, Guiglia R, Licata ME, Pizzo I, Davis JM, Giuliana G. Effect of hormone replacement therapy (hrt) on periodontak status of postmenopausal women. Med Sci Monit 2011;17(4):23-27. google scholar
  • Lundstrom A, Jendle J, Stenstrom B, Toss G, Ravald N. Periodontal conditions in 70-year-old women with osteoporosis. Swed Dent J 2001;25(3):89-96. google scholar
  • Amar S, Chung KM. Influence of hormonal variation on the periodontium in women. Periodontol 2000 1994;6:(79-87). google scholar
  • Daniell HW. Periodontitis in estrogen-deficient women. Arch Intern Med 2002;162(22):2634-2635. google scholar
  • Genco RJ, Grossi SG. Is estrogen deficiency a risk factor for periodontal disease? Compend Contin Educ Dent Suppl 1998;22, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1208975822):S23-29. google scholar
  • Geurs NC, Lewis CE, Jeffcoat MK. Osteoporosis and periodontal disease progression. Periodontol 2000 2003;32:(105-110). google scholar
  • Grossi SG. Effect of estrogen supplementation on periodontal disease. Compend Contin Educ Dent Suppl 1998;22, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1208975922):S30-36. google scholar
  • Hildebolt CF. Osteoporosis and oral bone loss.Dentomaxillofac Radiol 1997;26(1):3-15. google scholar
  • Inagaki K, Kurosu Y, Kamiya T, Kondo F, Yoshinari N, Noguchi T, Krall EA, Garcia RI. Low metacarpal bone density, tooth loss, and periodontal disease in japanese women. J Dent Res 2001;80(9):1818-1822. google scholar
  • Inagaki K, Noguchi T. [osteoporosis: A risk factor in periodontal disease]. Clin Calcium 2002;12(7):978-986. google scholar
  • Krook L, Whalen JP, Lesser GV, Lutwak L. Human periodontal disease and osteoporosis. Cornell Vet 1972;62(3):371-391. google scholar
  • Lai YL. Osteoporosis and periodontal disease. J Chin Med Assoc 2004;67(8):387-388. google scholar
  • Loza JC, Carpio LC, Dziak R. Osteoporosis and its relationship to oral bone loss. Curr Opin Periodontol 1996;3:(27-33). google scholar
  • Lundstrom A. JJ, Stenstrom B., Toss G., Ravald N. The physiology, medical management and oral implications of menopause. J Am Dent Assoc. 2002;133:(73-81). google scholar
  • Mohammad AR, Hooper DA, Vermilyea SG, Mariotti A, Preshaw PM. An investigation of the relationship between systemic bone density and clinical periodontal status in post-menopausal asian-american women. Int Dent J 2003;53(3):121-125. google scholar
  • Payne JB, Reinhardt RA, Masada MP, DuBois LM, Allison AC. Gingival crevicular fluid il-8: Correlation with local il-1 beta levels and patient estrogen status. J Periodontal Res 1993;(28):451-453. google scholar
  • Pilgram TK, Hildebolt CF, Yokoyama-Crothers N, Dotson M, Cohen SC, Hauser JF, Kardaris E. Relationships between radiographic alveolar bone height and probing attachment level: Data from healthy post-menopausal women. J Clin Periodontol 2000;27(5):341-346. google scholar
  • Shen EC, Gau CH, Hsieh YD, Chang CY, Fu E. Periodontal status in post-menopausal osteoporosis: A preliminary clinical study in taiwanese women. J Chin Med Assoc 2004;67(8):389-393. google scholar
  • Tezal M, Wactawski-Wende J, Grossi SG, Ho AW, Dunford R, Genco RJ. The relationship between bone mineral density and periodontitis in postmenopausal women. J Periodontol 2000;71(9):1492-1498. google scholar
  • Daltaban O, Saygun I, Bal B, Balos K, Serdar M. Gingival crevicular fluid alkaline phosphatase levels in postmenopausal women: Effects of phase i periodontal treatment. J Periodontol 2006;77(1):67-72. google scholar
  • Norderyd OM, Grossi SG, Machtei EE, Zambon JJ, Hausmann E, Dunford RG, Genco RJ. Periodontal status of women taking postmenopausal estrogen supplementation. J Periodontol 1993;64(10):957-962. google scholar
  • Lopez-Marcos JF, Garcia-Valle S, Garcia-Iglesias AA. Periodontal aspects in menopausal women undergoing hormone replacement therapy. Med Oral Patol Oral Cir Bucal 2005;10(2):132-141. google scholar
  • Silness J, Loe H. Periodontal disease in pregnancy. Ii. Correlation between oral hygiene and periodontal condtion. Acta Odontol Scand 1964;22:(121-135). google scholar
  • Muhlemann HR, Son S. Gingival sulcus bleeding--a leading symptom in initial gingivitis. Helv Odontol Acta 1971;15(2):107-113. google scholar
  • Pilgram TK, Hildebolt CF, Yokoyama-Crothers N, Dotson M, Cohen SC, Hauser JF, Kardaris E. Relationships between longitudinal changes in radiographic alveolar bone height and probing depth measurements: Data from postmenopausal women. J Periodontol 1999;70(8):829-833. google scholar
  • Mohammad AR, Brunsvold M, Bauer R. The strength of association between systemic postmenopausal osteoporosis and periodontal disease. Int J Prosthodont 1996;9(5):479-483. google scholar
  • Mealey BL, Moritz AJ. Hormonal influences: Effects of diabetes mellitus and endogenous female sex steroid hormones on the periodontium. Periodontol 2000 2003;32:(59-81). google scholar
  • Garcia RI, Henshaw MM, Krall EA. Relationship between periodontal disease and systemic health. Periodontol 2000 2001;25(21-36). google scholar
  • Straub RH. The complex role of estrogens in inflammation. Endocr Rev 2007;28(5):521-574. google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Çekici, A., Başer, Ü., Işık, G., Akhan, S.E., İşsever, H., & Onan, U. (2015). PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY. European Oral Research, 49(3), 39-44. https://doi.org/10.17096/jiufd.61637


AMA

Çekici A, Başer Ü, Işık G, Akhan S E, İşsever H, Onan U. PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY. European Oral Research. 2015;49(3):39-44. https://doi.org/10.17096/jiufd.61637


ABNT

Çekici, A.; Başer, Ü.; Işık, G.; Akhan, S.E.; İşsever, H.; Onan, U. PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY. European Oral Research, [Publisher Location], v. 49, n. 3, p. 39-44, 2015.


Chicago: Author-Date Style

Çekici, Ali, and Ülkü Başer and Gülden Işık and Süleyman Engin Akhan and Halim İşsever and Utku Onan. 2015. “PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY.” European Oral Research 49, no. 3: 39-44. https://doi.org/10.17096/jiufd.61637


Chicago: Humanities Style

Çekici, Ali, and Ülkü Başer and Gülden Işık and Süleyman Engin Akhan and Halim İşsever and Utku Onan. “PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY.” European Oral Research 49, no. 3 (Dec. 2024): 39-44. https://doi.org/10.17096/jiufd.61637


Harvard: Australian Style

Çekici, A & Başer, Ü & Işık, G & Akhan, SE & İşsever, H & Onan, U 2015, 'PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY', European Oral Research, vol. 49, no. 3, pp. 39-44, viewed 22 Dec. 2024, https://doi.org/10.17096/jiufd.61637


Harvard: Author-Date Style

Çekici, A. and Başer, Ü. and Işık, G. and Akhan, S.E. and İşsever, H. and Onan, U. (2015) ‘PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY’, European Oral Research, 49(3), pp. 39-44. https://doi.org/10.17096/jiufd.61637 (22 Dec. 2024).


MLA

Çekici, Ali, and Ülkü Başer and Gülden Işık and Süleyman Engin Akhan and Halim İşsever and Utku Onan. “PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY.” European Oral Research, vol. 49, no. 3, 2015, pp. 39-44. [Database Container], https://doi.org/10.17096/jiufd.61637


Vancouver

Çekici A, Başer Ü, Işık G, Akhan SE, İşsever H, Onan U. PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY. European Oral Research [Internet]. 22 Dec. 2024 [cited 22 Dec. 2024];49(3):39-44. Available from: https://doi.org/10.17096/jiufd.61637 doi: 10.17096/jiufd.61637


ISNAD

Çekici, Ali - Başer, Ülkü - Işık, Gülden - Akhan, SüleymanEngin - İşsever, Halim - Onan, Utku. “PERİODONTAL TREATMENT OUTCOMES IN POST MENOPAUSAL WOMEN RECEIVING HORMONE REPLACEMENT THERAPY”. European Oral Research 49/3 (Dec. 2024): 39-44. https://doi.org/10.17096/jiufd.61637



TIMELINE


Submitted05.08.2015
Accepted20.10.2015
Published Online05.08.2015

SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.