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DOI :10.26650/eor.20231225662   IUP :10.26650/eor.20231225662    Full Text (PDF)

Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

Tivanani V D Mahendra, Tavva Santhosh Rahul, Santosh Venkata Ramesh Konathala, P Swetha, V Sai Sai Keerthi, Vyshnavi M

Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement (GIC) doped with 3% and 5% (w/w) titanium dioxide nanoparticles (TiO2-NPs), and to evaluate their antibacterial properties.

Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3% and 5% w/w modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. The samples were quantified over four-time periods: 24 hours, two months, four months, and six months, using inductively coupled plasma mass spectroscopy (ICP-MS), antibacterial properties were evaluated by means of colony forming count (CFU) method.

Results: The amount of titanium ions released from the discs that received 3%(w/w) TiO2 was highest in the first two months, with no significant release at successive intervals. Also, the second group, which included 5% (w/w) TiO2, saw a considerable ion release at every interval, with the second month seeing the maximum release. The levels in the 5% (w/w) group were consistently higher when the two concentrations were compared at each of the four time points, indicating a considerable increase in titanium release and antibacterial property with a concentration increase from 3% to 5%.

Conclusion: 3% and 5% (w/w) concentrations may be considered safe and exhibit significant antimicrobial effect, titanium ions were discharged at higher rates in 5% (w/w) modified GIC containing TiO2-NPs than in 3% (w/w) modified GIC containing TiO2-NPs.

Keywords: Antibacterial, Glass ionomer cement, Ion release, saliva, Titanium dioxide.

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APA

Mahendra, T.V., Rahul, T.S., Konathala, S.V., Swetha, P., Sai Keerthi, V.S., & M, V. (2023). Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study. European Oral Research, 58(1), 8-13. https://doi.org/10.26650/eor.20231225662


AMA

Mahendra T V, Rahul T S, Konathala S V, Swetha P, Sai Keerthi V S, M V. Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study. European Oral Research. 2023;58(1):8-13. https://doi.org/10.26650/eor.20231225662


ABNT

Mahendra, T.V.; Rahul, T.S.; Konathala, S.V.; Swetha, P.; Sai Keerthi, V.S.; M, V. Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study. European Oral Research, [Publisher Location], v. 58, n. 1, p. 8-13, 2023.


Chicago: Author-Date Style

Mahendra, Tivanani V D, and Tavva Santhosh Rahul and Santosh Venkata Ramesh Konathala and P Swetha and V Sai Sai Keerthi and Vyshnavi M. 2023. “Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study.” European Oral Research 58, no. 1: 8-13. https://doi.org/10.26650/eor.20231225662


Chicago: Humanities Style

Mahendra, Tivanani V D, and Tavva Santhosh Rahul and Santosh Venkata Ramesh Konathala and P Swetha and V Sai Sai Keerthi and Vyshnavi M. “Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study.” European Oral Research 58, no. 1 (Nov. 2024): 8-13. https://doi.org/10.26650/eor.20231225662


Harvard: Australian Style

Mahendra, TV & Rahul, TS & Konathala, SV & Swetha, P & Sai Keerthi, VS & M, V 2023, 'Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study', European Oral Research, vol. 58, no. 1, pp. 8-13, viewed 22 Nov. 2024, https://doi.org/10.26650/eor.20231225662


Harvard: Author-Date Style

Mahendra, T.V. and Rahul, T.S. and Konathala, S.V. and Swetha, P. and Sai Keerthi, V.S. and M, V. (2023) ‘Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study’, European Oral Research, 58(1), pp. 8-13. https://doi.org/10.26650/eor.20231225662 (22 Nov. 2024).


MLA

Mahendra, Tivanani V D, and Tavva Santhosh Rahul and Santosh Venkata Ramesh Konathala and P Swetha and V Sai Sai Keerthi and Vyshnavi M. “Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study.” European Oral Research, vol. 58, no. 1, 2023, pp. 8-13. [Database Container], https://doi.org/10.26650/eor.20231225662


Vancouver

Mahendra TV, Rahul TS, Konathala SV, Swetha P, Sai Keerthi VS, M V. Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study. European Oral Research [Internet]. 22 Nov. 2024 [cited 22 Nov. 2024];58(1):8-13. Available from: https://doi.org/10.26650/eor.20231225662 doi: 10.26650/eor.20231225662


ISNAD

Mahendra, TivananiV D - Rahul, TavvaSanthosh - Konathala, SantoshVenkata Ramesh - Swetha, P - Sai Keerthi, VSai - M, Vyshnavi. “Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study”. European Oral Research 58/1 (Nov. 2024): 8-13. https://doi.org/10.26650/eor.20231225662



TIMELINE


Submitted29.12.2022
First Revision22.02.2023
Accepted02.03.2023
Published Online10.05.2023

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