Release of mercury from amalgam filling and its relationship with metallothionein and  superoxide dismutase

Gül Pınar; Karataş Özcan; Sağsöz Ömer; Aşkın Seda; Türkeri Özge; Kızıltunç Ahmet

doi:https://dx.doi.org/10.26650/eor.20231086355

Research Article

DOI :10.26650/eor.20231086355 IUP :10.26650/eor.20231086355 Full Text (PDF)

Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase

Pınar Gül, Özcan Karataş, Ömer Sağsöz, Seda Aşkın, Özge Türkeri, Ahmet Kızıltunç

Purpose This study aims at determining the amount of mercury released over time from amalgam after treatment in healthy subjects and to examine the relation of mercury with serum MT-1 and SOD-1 levels. Materials and Methods Amalgam filling was applied to the 15 subjects aged 19-22 years and blood samples were collected before treatment and 1 day, 7 days, 21 days and 35 days after treatment. Mercury analysis of serum samples was performed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In addition, MT-1 and SOD-1 levels in serum samples were measured using commercial enzyme-linked immunosorbent assay (ELISA). Friedman test and Spearman’s correlation analysis was performed to analyse the data. p value was interpreted in significance level of 0.05. Results As a result of the analysis for MT-1, it was found that the values decreased over time and this decrease was statistically significant after 21 days (p<0.05). In addition, it was found that SOD-1 decreased over time, but this decrease was not statistically significant . In terms of released mercury, there was no statistically significant difference among the values of mercury released over time . According to the results of correlation analysis, no statistically significant relationship was found among the variables. Conclusion The results of the present study indicated that the amount of mercury released from the tested amalgam were found to be tolerable and no significant relationship was found between MT-1 and SOD-1.

Keywords: Amalgam, antioxidants, mercury, metallothionein, superoxide dismutase

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APA

Gül, P., Karataş, Ö., Sağsöz, Ö., Aşkın, S., Türkeri, Ö., & Kızıltunç, A. (2023). Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase. European Oral Research, 57(1), 16-21. https://doi.org/10.26650/eor.20231086355

AMA

Gül P, Karataş Ö, Sağsöz Ö, Aşkın S, Türkeri Ö, Kızıltunç A. Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase. European Oral Research. 2023;57(1):16-21. https://doi.org/10.26650/eor.20231086355

ABNT

Gül, P.; Karataş, Ö.; Sağsöz, Ö.; Aşkın, S.; Türkeri, Ö.; Kızıltunç, A. Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase. European Oral Research, [Publisher Location], v. 57, n. 1, p. 16-21, 2023.

Chicago: Author-Date Style

Gül, Pınar, and Özcan Karataş and Ömer Sağsöz and Seda Aşkın and Özge Türkeri and Ahmet Kızıltunç. 2023. “Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase.” European Oral Research 57, no. 1: 16-21. https://doi.org/10.26650/eor.20231086355

Chicago: Humanities Style

Gül, Pınar, and Özcan Karataş and Ömer Sağsöz and Seda Aşkın and Özge Türkeri and Ahmet Kızıltunç. “Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase.” European Oral Research 57, no. 1 (Apr. 2024): 16-21. https://doi.org/10.26650/eor.20231086355

Harvard: Australian Style

Gül, P & Karataş, Ö & Sağsöz, Ö & Aşkın, S & Türkeri, Ö & Kızıltunç, A 2023, 'Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase', European Oral Research, vol. 57, no. 1, pp. 16-21, viewed 19 Apr. 2024, https://doi.org/10.26650/eor.20231086355

Harvard: Author-Date Style

Gül, P. and Karataş, Ö. and Sağsöz, Ö. and Aşkın, S. and Türkeri, Ö. and Kızıltunç, A. (2023) ‘Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase’, European Oral Research, 57(1), pp. 16-21. https://doi.org/10.26650/eor.20231086355 (19 Apr. 2024).

MLA

Gül, Pınar, and Özcan Karataş and Ömer Sağsöz and Seda Aşkın and Özge Türkeri and Ahmet Kızıltunç. “Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase.” European Oral Research, vol. 57, no. 1, 2023, pp. 16-21. [Database Container], https://doi.org/10.26650/eor.20231086355

Vancouver

Gül P, Karataş Ö, Sağsöz Ö, Aşkın S, Türkeri Ö, Kızıltunç A. Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase. European Oral Research [Internet]. 19 Apr. 2024 [cited 19 Apr. 2024];57(1):16-21. Available from: https://doi.org/10.26650/eor.20231086355 doi: 10.26650/eor.20231086355

ISNAD

Gül, Pınar - Karataş, Özcan - Sağsöz, Ömer - Aşkın, Seda - Türkeri, Özge - Kızıltunç, Ahmet. “Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase”. European Oral Research 57/1 (Apr. 2024): 16-21. https://doi.org/10.26650/eor.20231086355

Volume 57, Issue 12023, P. 16-21

TIMELINE

Submitted	11.03.2022
Accepted	07.05.2022
Published Online	05.09.2022

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