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Research Article


DOI :10.26650/eor.20190041   IUP :10.26650/eor.20190041    Full Text (PDF)

The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis

Erman Senel, Enes Özkan, Mehmet Cihan Bereket, Mehmet Emin Önger

Purpose 
This study aims to evaluate the effects of extracorporeal shock wave therapy applied before and/or immediately after the osteotomy on the maturation during the consolidation phase. 

Materials and Methods 
21 female New Zealand rabbits were used in the study. Subjects were divided randomly into three groups: Control (Distraction without ESWT), A (Distraction +ESWT After Osteotomy), AB (Distraction+ESWT After and Before Osteotomy). ESWT (500 pulses, 5 Hz, 0.19 mJ/mm2 energy flux density) was applied to group A and group AB after 5, 12 and 19 days after osteotomy and group AB only on days 7,14 and 21 before osteotomy. On the 28th day of the consolidation period, all subjects were sacrificed. Dual-energy x-ray absorptiometry (DEXA) was used to determine bone mineral density (BMD) and bone mineral content (BMC), and stereological methods were used to determine the new bone, connective tissue and neovascularization volumes. 

Results 
As a result of DEXA examinations made on the 1st and 4th week of consolidation, there was no significant difference between groups regarding BMD and BMC values. According to the results of stereological examination, when the connective tissue and new bone tissue were evaluated, higher values were observed in AB when compared to A, and in AB and A compared to the control group, but the differences are not statistically significant. There was no difference between the groups in terms of neovascularization. 

Conclusion 
ESWT in these parameters was not positively effective in bone maturation during consolidation when applied before osteotomy or both before and after osteotomy. 
Keywords: Bone regeneration, distraction osteogenesis, dual-energy x-ray absorptiometry, extracorporeal shock wave therapy, organ volume

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APA

Senel, E., Özkan, E., Bereket, M.C., & Önger, M.E. (2019). The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis. European Oral Research, 53(3), 125-131. https://doi.org/10.26650/eor.20190041


AMA

Senel E, Özkan E, Bereket M C, Önger M E. The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis. European Oral Research. 2019;53(3):125-131. https://doi.org/10.26650/eor.20190041


ABNT

Senel, E.; Özkan, E.; Bereket, M.C.; Önger, M.E. The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis. European Oral Research, [Publisher Location], v. 53, n. 3, p. 125-131, 2019.


Chicago: Author-Date Style

Senel, Erman, and Enes Özkan and Mehmet Cihan Bereket and Mehmet Emin Önger. 2019. “The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis.” European Oral Research 53, no. 3: 125-131. https://doi.org/10.26650/eor.20190041


Chicago: Humanities Style

Senel, Erman, and Enes Özkan and Mehmet Cihan Bereket and Mehmet Emin Önger. “The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis.” European Oral Research 53, no. 3 (May. 2024): 125-131. https://doi.org/10.26650/eor.20190041


Harvard: Australian Style

Senel, E & Özkan, E & Bereket, MC & Önger, ME 2019, 'The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis', European Oral Research, vol. 53, no. 3, pp. 125-131, viewed 12 May. 2024, https://doi.org/10.26650/eor.20190041


Harvard: Author-Date Style

Senel, E. and Özkan, E. and Bereket, M.C. and Önger, M.E. (2019) ‘The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis’, European Oral Research, 53(3), pp. 125-131. https://doi.org/10.26650/eor.20190041 (12 May. 2024).


MLA

Senel, Erman, and Enes Özkan and Mehmet Cihan Bereket and Mehmet Emin Önger. “The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis.” European Oral Research, vol. 53, no. 3, 2019, pp. 125-131. [Database Container], https://doi.org/10.26650/eor.20190041


Vancouver

Senel E, Özkan E, Bereket MC, Önger ME. The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis. European Oral Research [Internet]. 12 May. 2024 [cited 12 May. 2024];53(3):125-131. Available from: https://doi.org/10.26650/eor.20190041 doi: 10.26650/eor.20190041


ISNAD

Senel, Erman - Özkan, Enes - Bereket, MehmetCihan - Önger, MehmetEmin. “The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis”. European Oral Research 53/3 (May. 2024): 125-131. https://doi.org/10.26650/eor.20190041



TIMELINE


Submitted20.09.2018
Accepted08.02.2019
Published Online10.09.2019

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