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DOI :10.26650/experimed.1494644   IUP :10.26650/experimed.1494644    Full Text (PDF)

Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases

Ezgi Değerli, Selcan Cesur, Ahmet Yavuz, Mahmut Said Değerli, Zeynep Ermiş Karaali

Objective: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), presents ongoing challenges in terms of diagnosis and management. With increasing treatment options, reliable markers for assessing treatment response have become crucial. This study explored the potential of apelin, a peptide hormone implicated in inflammation, as a biomarker for monitoring disease activity in patients with IBD undergoing colonoscopy.

Materials and Methods: The study included 91 patients who were followed up for IBD. Apelin levels were measured in serum, and the site of involvement was simultaneously examined by colonoscopy. Alternations of apelin levels depending on the location of involvement was also considered.

Results: Despite the widespread presence of apelin in the gastrointestinal system (GIS), our findings did not reveal significant differences in apelin levels among patients with varying colonoscopic involvement (p=0.73).

Conclusion: Although apelin has potential as a biomarker of gastrointestinal inflammation in IBD, its precise role and clinical applicability necessitate comprehensive studies involving larger patient populations. Future research on apelin and IBD could refine its utility in disease monitoring and enhance its diagnostic significance. 

Keywords: Inflammatory bowel disease, apelin, Crohn's disease, ulcerative colitis

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APA

Değerli, E., Cesur, S., Yavuz, A., Değerli, M.S., & Ermiş Karaali, Z. (2024). Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases. Experimed, 14(2), 126-130. https://doi.org/10.26650/experimed.1494644


AMA

Değerli E, Cesur S, Yavuz A, Değerli M S, Ermiş Karaali Z. Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases. Experimed. 2024;14(2):126-130. https://doi.org/10.26650/experimed.1494644


ABNT

Değerli, E.; Cesur, S.; Yavuz, A.; Değerli, M.S.; Ermiş Karaali, Z. Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases. Experimed, [Publisher Location], v. 14, n. 2, p. 126-130, 2024.


Chicago: Author-Date Style

Değerli, Ezgi, and Selcan Cesur and Ahmet Yavuz and Mahmut Said Değerli and Zeynep Ermiş Karaali. 2024. “Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases.” Experimed 14, no. 2: 126-130. https://doi.org/10.26650/experimed.1494644


Chicago: Humanities Style

Değerli, Ezgi, and Selcan Cesur and Ahmet Yavuz and Mahmut Said Değerli and Zeynep Ermiş Karaali. “Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases.” Experimed 14, no. 2 (Dec. 2024): 126-130. https://doi.org/10.26650/experimed.1494644


Harvard: Australian Style

Değerli, E & Cesur, S & Yavuz, A & Değerli, MS & Ermiş Karaali, Z 2024, 'Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases', Experimed, vol. 14, no. 2, pp. 126-130, viewed 21 Dec. 2024, https://doi.org/10.26650/experimed.1494644


Harvard: Author-Date Style

Değerli, E. and Cesur, S. and Yavuz, A. and Değerli, M.S. and Ermiş Karaali, Z. (2024) ‘Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases’, Experimed, 14(2), pp. 126-130. https://doi.org/10.26650/experimed.1494644 (21 Dec. 2024).


MLA

Değerli, Ezgi, and Selcan Cesur and Ahmet Yavuz and Mahmut Said Değerli and Zeynep Ermiş Karaali. “Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases.” Experimed, vol. 14, no. 2, 2024, pp. 126-130. [Database Container], https://doi.org/10.26650/experimed.1494644


Vancouver

Değerli E, Cesur S, Yavuz A, Değerli MS, Ermiş Karaali Z. Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases. Experimed [Internet]. 21 Dec. 2024 [cited 21 Dec. 2024];14(2):126-130. Available from: https://doi.org/10.26650/experimed.1494644 doi: 10.26650/experimed.1494644


ISNAD

Değerli, Ezgi - Cesur, Selcan - Yavuz, Ahmet - Değerli, MahmutSaid - Ermiş Karaali, Zeynep. “Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases”. Experimed 14/2 (Dec. 2024): 126-130. https://doi.org/10.26650/experimed.1494644



TIMELINE


Submitted03.06.2024
Accepted05.08.2024
Published Online26.08.2024

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