Research Article


DOI :10.26650/experimed.1443398   IUP :10.26650/experimed.1443398    Full Text (PDF)

The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure

Najiullah FazalyarSeren Ede PazarbaşıDoğancan DorucuGöksel ŞenerTuğba Tunalı Akbay

Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress.

Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined.

Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group.

Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.


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APA

Fazalyar, N., Ede Pazarbaşı, S., Dorucu, D., Şener, G., & Tunalı Akbay, T. (2024). The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure. Experimed, 14(2), 68-72. https://doi.org/10.26650/experimed.1443398


AMA

Fazalyar N, Ede Pazarbaşı S, Dorucu D, Şener G, Tunalı Akbay T. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure. Experimed. 2024;14(2):68-72. https://doi.org/10.26650/experimed.1443398


ABNT

Fazalyar, N.; Ede Pazarbaşı, S.; Dorucu, D.; Şener, G.; Tunalı Akbay, T. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure. Experimed, [Publisher Location], v. 14, n. 2, p. 68-72, 2024.


Chicago: Author-Date Style

Fazalyar, Najiullah, and Seren Ede Pazarbaşı and Doğancan Dorucu and Göksel Şener and Tuğba Tunalı Akbay. 2024. “The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure.” Experimed 14, no. 2: 68-72. https://doi.org/10.26650/experimed.1443398


Chicago: Humanities Style

Fazalyar, Najiullah, and Seren Ede Pazarbaşı and Doğancan Dorucu and Göksel Şener and Tuğba Tunalı Akbay. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure.” Experimed 14, no. 2 (Dec. 2024): 68-72. https://doi.org/10.26650/experimed.1443398


Harvard: Australian Style

Fazalyar, N & Ede Pazarbaşı, S & Dorucu, D & Şener, G & Tunalı Akbay, T 2024, 'The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure', Experimed, vol. 14, no. 2, pp. 68-72, viewed 21 Dec. 2024, https://doi.org/10.26650/experimed.1443398


Harvard: Author-Date Style

Fazalyar, N. and Ede Pazarbaşı, S. and Dorucu, D. and Şener, G. and Tunalı Akbay, T. (2024) ‘The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure’, Experimed, 14(2), pp. 68-72. https://doi.org/10.26650/experimed.1443398 (21 Dec. 2024).


MLA

Fazalyar, Najiullah, and Seren Ede Pazarbaşı and Doğancan Dorucu and Göksel Şener and Tuğba Tunalı Akbay. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure.” Experimed, vol. 14, no. 2, 2024, pp. 68-72. [Database Container], https://doi.org/10.26650/experimed.1443398


Vancouver

Fazalyar N, Ede Pazarbaşı S, Dorucu D, Şener G, Tunalı Akbay T. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure. Experimed [Internet]. 21 Dec. 2024 [cited 21 Dec. 2024];14(2):68-72. Available from: https://doi.org/10.26650/experimed.1443398 doi: 10.26650/experimed.1443398


ISNAD

Fazalyar, Najiullah - Ede Pazarbaşı, Seren - Dorucu, Doğancan - Şener, Göksel - Tunalı Akbay, Tuğba. The Effects of Panax ginseng on Serum Oxidative Stress Following Bisphenol A Exposure”. Experimed 14/2 (Dec. 2024): 68-72. https://doi.org/10.26650/experimed.1443398



TIMELINE


Submitted27.02.2024
Accepted03.05.2024
Published Online31.05.2024

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