İstanbul Journal of Pharmacy

SUBMITINFORMATION
EnglishTürkçe

Research Article


DOI :10.26650/IstanbulJPharm.2022.894762   IUP :10.26650/IstanbulJPharm.2022.894762    Full Text (PDF)

Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.

Seçil Karahüseyin, Aynur Sarı, Nurten Özsoy

Background and Aims: The genus Taraxacum is a member of the family Asteraceae. Taraxacum species are widely distributed in the warmer temperate zones of the Northern Hemisphere. The aim of this study was to evaluate the phenolic contents and antioxidant activity of the ethanol extract and its chloroform and ethyl acetate fractions from the roots of Taraxacum gracilens Dahlst. and isolate some of its phenolic compounds. Methods: The roots of T. gracilens Dahlst. werefirst macerated with EtOH and fractionated to obtain chloroform and ethyl acetate fractions, and then phenolic compounds were isolated by column chromatography. The polyphenolic contents and antioxidant activities of the fractions were evaluated by measuring their abilities to inhibit lipid peroxidation induced by Fe3+- ascorbate, their reducing powers, and their hydrogen-donor activities. Results: Three phenolic compounds [vanillic acid (1), caffeic acid (2) and luteolin (3)] were isolated from the roots of T. gracilens Dahlst. The ethyl acetate fraction from the ethanol extract of T. gracilens Dahlst. roots showed the highest antioxidant activity due to its richest phenolic contents, whereas the ethanol extract containing the least phenolics was the weakest in activity. Conclusion: The fractions have potential to act as antioxidant agents. T. gracilens Dahlst. roots were investigated for the first time in literature data in terms of phenolic contents and antioxidant activity.

Keywords: Taraxacum gracilens dahlst., Root, Phenolic compounds, Antioxidant activity

PDF View

References

  • Benzie, I., & Strain, J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP assay. Ana-lytical Biochemistry, 239, 70-76. google scholar
  • Brand-Williams, W., Cuvelier, M., & Berset, C. (1995). Use of a free radical method to evaluate antioxidant activity. Lebensmittel-Wis-senschaft Und Technologie, 28, 25-30. google scholar
  • Budzianowski, J. (1997). Coumarins, Caffeoyltartaric acids and their artifactual methyl esters from taraxacum officinale Leaves. Planta Medica, 63(03), 288-288. https://doi.org/10.1055/s-2006-957681 google scholar
  • Duh, P.-D., Tu, Y.-Y., & Yen, G.-C. (1999). Antioxidant activity of wa-ter extract of Harng Jyur (Chrysanthemum morifolium ramat). Lebensmıttel-Wıssenschaft Und Technologıe, 32, 269-277. google scholar
  • Hu, C. (2018). Taraxacum: Phytochemistry and health benefits. Chinese Herbal Medicines, 10(4), 353-361. https://doi.org/10.1016/j. chmed.2018.08.003 google scholar
  • Ivanov, I. G. (2014). polyphenols content and antioxidant activities of taraxacum officinale F.H. Wigg (Dandelion) Leaves. Available Online on Www.Ijppr.Com International Journal of Pharmacognosy and Phytochemical Research, 6(4). Retrieved from www.ijppr.com google scholar
  • Jedrejek, D., Lis, B., Rolnik, A., Stochmal, A., & Olas, B. (2019). Com-parative phytochemical, cytotoxicity, antioxidant and haemo-static studies of Taraxacum officinale root preparations. Food and Chemical Toxicology, 126, 233-247. https://doi.org/10.1016/J. FCT.2019.02.017 google scholar
  • Kenny, O., Smyth, T. J., Hewage, C. M., Brunton, N. P., & McLough-lin, P. (2014). 4-Hydroxyphenylacetic acid derivatives of inositol from dandelion (Taraxacum officinale) root characterised using LC-SPE-NMR and LC-MS techniques. Phytochemistry, 98, 197-203. https://doi.org/10.1016/j.phytochem.2013.11.022 google scholar
  • Kenny, Owen, J Smyth, T., M Hewage, C., & P Brunton, N. (2014). Antioxidant properties and quantitative UPLC-MS/MS analysis of phenolic compounds in dandelion (Taraxacum officinale) root extracts. Free Radicals and Antioxidants, 4(1), 55-61. https://doi. org/10.5530/fra.2014.1.9 google scholar
  • Kenny, Owen, Smyth, T. J., Hewage, C. M., & Brunton, N. P. (2015). Quantitative UPLC-MS/MS analysis of chlorogenic acid deriva-tives in antioxidant fractionates from dandelion (Taraxacum of-ficinale) root. International Journal of Food Science and Technology, 50(3), 766-773. https://doi.org/10.1111/ijfs.12668 google scholar
  • Leu, Y. L., Wang, Y. L., Huang, S. C., & Shi, L. S. (2005). Chemical constituents from roots of Taraxacum formosanum. Chemical and Pharmaceutical Bulletin, 53(7), 853-855. https://doi.org/10.1248/ cpb.53.853 google scholar
  • Martinez, M., Poirrier, P., Chamy, R., Prüfer, D., Schulze-Gronover, C., Jorquera, L., & Ruiz, G. (2015). Taraxacum officinale and related species - An ethnopharmacological review and its potential as a commercial medicinal plant. Journal of Ethnopharmacology, 169, 244-262. https://doi.org/10.1016/j.jep.2015.03.067 google scholar
  • Pratt, D. E. (1976). Food Flavors. In G. Charalambous & I. Katz (Eds.), Phenolic, Sulfur and Nitrogen Compounds. Washington, DC.: Amer-ican Chemical Society. google scholar
  • Schütz, K., Carle, R., & Schieber, A. (2006, October 11). Taraxacum-A review on its phytochemical and pharmacological profile. Journal of Ethnopharmacology, Vol. 107, pp. 313-323. https://doi. org/10.1016/j.jep.2006.07.021 google scholar
  • Slinkard, K., & Singleton, V. (1977). Total phenol analyses: automa-tion and comparison with manual methods. American Journal of Enology and Viticulture, 28, 49-55. google scholar
  • Stefano, L. G., Bruna, E., Virginia, F., & Giuliano Bonanomi, L. (2019). Common dandelion: a review of its botanical, phytochemical and pharmacological profiles. Phytochemistry Reviews, 1-18. https:// doi.org/10.1007/s11101-019-09622-2 google scholar
  • Williams, C. A., Goldstone, F., & Greenham, J. (1996). Flavonoids, cinnamic acids and coumarins from the different tissues and me-dicinal preparations of Taraxacum officinale. Phytochemistry, 42(1), 121-127. https://doi.org/10.1016/0031-9422(95)00865-9 google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Karahüseyin, S., Sarı, A., & Özsoy, N. (2022). Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.. İstanbul Journal of Pharmacy, 52(1), 69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762


AMA

Karahüseyin S, Sarı A, Özsoy N. Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.. İstanbul Journal of Pharmacy. 2022;52(1):69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762


ABNT

Karahüseyin, S.; Sarı, A.; Özsoy, N. Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.. İstanbul Journal of Pharmacy, [Publisher Location], v. 52, n. 1, p. 69-72, 2022.


Chicago: Author-Date Style

Karahüseyin, Seçil, and Aynur Sarı and Nurten Özsoy. 2022. “Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst..” İstanbul Journal of Pharmacy 52, no. 1: 69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762


Chicago: Humanities Style

Karahüseyin, Seçil, and Aynur Sarı and Nurten Özsoy. “Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst..” İstanbul Journal of Pharmacy 52, no. 1 (May. 2024): 69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762


Harvard: Australian Style

Karahüseyin, S & Sarı, A & Özsoy, N 2022, 'Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.', İstanbul Journal of Pharmacy, vol. 52, no. 1, pp. 69-72, viewed 11 May. 2024, https://doi.org/10.26650/IstanbulJPharm.2022.894762


Harvard: Author-Date Style

Karahüseyin, S. and Sarı, A. and Özsoy, N. (2022) ‘Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.’, İstanbul Journal of Pharmacy, 52(1), pp. 69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762 (11 May. 2024).


MLA

Karahüseyin, Seçil, and Aynur Sarı and Nurten Özsoy. “Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst..” İstanbul Journal of Pharmacy, vol. 52, no. 1, 2022, pp. 69-72. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2022.894762


Vancouver

Karahüseyin S, Sarı A, Özsoy N. Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.. İstanbul Journal of Pharmacy [Internet]. 11 May. 2024 [cited 11 May. 2024];52(1):69-72. Available from: https://doi.org/10.26650/IstanbulJPharm.2022.894762 doi: 10.26650/IstanbulJPharm.2022.894762


ISNAD

Karahüseyin, Seçil - Sarı, Aynur - Özsoy, Nurten. “Antioxidant activity and three phenolic compounds from the roots of Taraxacum gracilens Dahlst.”. İstanbul Journal of Pharmacy 52/1 (May. 2024): 69-72. https://doi.org/10.26650/IstanbulJPharm.2022.894762



TIMELINE


Submitted11.03.2021
Accepted23.02.2022
Published Online28.04.2022

LICENCE


Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.


SHARE




Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.