İstanbul Journal of Pharmacy

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DOI :10.26650/IstanbulJPharm.2023.1329006   IUP :10.26650/IstanbulJPharm.2023.1329006    Full Text (PDF)

Antioxidant supplements: Positive or negative actors in orthodontic treatment

Rümeysa Bilici Geçer, Gül Özhan, Derya Dursun

Antioxidant supplements are popular and commonly considered healthy benefits such as reducing the risk of disease. It should be noted that their advantages/disadvantages are still unclear. Some research on antioxidants shows that they may reduce the risk of cancer, heart disease, neurodegenerative diseases, and some chronic diseases, and have various health benefits such as a positive effect on bone metabolism by supporting bone regeneration. Some of them show that the benefits of antioxidant supplements are not clear and indicate to increase the risk. The effects of antioxidants on orthodontic treatment are now being studied extensively due to their widespread use. Antioxidants that regulate bone modulation can be used to reduce orthodontic treatment time, accelerate tooth movement, or in some cases prevent unwanted tooth movement, but their unconscious use can adversely affect the orthodontic treatment. Understanding the mechanisms of action of antioxidants and their effects on orthodontic treatment can increase the success of treatment and prevent adverse situations that may occur due to the use of antioxidants. Many inflammatory mediators play a role in the response to mechanical forces in orthodontic treatment. Increased expression of pro-inflammatory cytokines is associated with oxidative stress. Antioxidants can affect remodeling processes in which osteoblast and osteoclast cells play a role, such as relapse, anchorage, and bone formation after maxillary expansion in orthodontic treatment. The use of antioxidants in orthodontic treatment may increase tooth movement and shorten retention time by increasing osteoblastic activity after maxillary expansion, or on the contrary, slow tooth movement and prolong treatment time by reducing oxidative stress and inflammation. Accordingly, factors such as the desired effect in orthodontic treatment and the phase of treatment should be considered when using antioxidants. We aimed to provide information and suggestions for evaluating the effectiveness of antioxidant use in orthodontic treatment with basic information about antioxidants. 

Keywords: Antioxidant supplements, orthodontic treatment, oxidative stress

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Citations

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APA

Bilici Geçer, R., Özhan, G., & Dursun, D. (2023). Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy, 53(3), 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006


AMA

Bilici Geçer R, Özhan G, Dursun D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy. 2023;53(3):358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006


ABNT

Bilici Geçer, R.; Özhan, G.; Dursun, D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy, [Publisher Location], v. 53, n. 3, p. 358-367, 2023.


Chicago: Author-Date Style

Bilici Geçer, Rümeysa, and Gül Özhan and Derya Dursun. 2023. “Antioxidant supplements: Positive or negative actors in orthodontic treatment.” İstanbul Journal of Pharmacy 53, no. 3: 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006


Chicago: Humanities Style

Bilici Geçer, Rümeysa, and Gül Özhan and Derya Dursun. “Antioxidant supplements: Positive or negative actors in orthodontic treatment.” İstanbul Journal of Pharmacy 53, no. 3 (Apr. 2024): 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006


Harvard: Australian Style

Bilici Geçer, R & Özhan, G & Dursun, D 2023, 'Antioxidant supplements: Positive or negative actors in orthodontic treatment', İstanbul Journal of Pharmacy, vol. 53, no. 3, pp. 358-367, viewed 28 Apr. 2024, https://doi.org/10.26650/IstanbulJPharm.2023.1329006


Harvard: Author-Date Style

Bilici Geçer, R. and Özhan, G. and Dursun, D. (2023) ‘Antioxidant supplements: Positive or negative actors in orthodontic treatment’, İstanbul Journal of Pharmacy, 53(3), pp. 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006 (28 Apr. 2024).


MLA

Bilici Geçer, Rümeysa, and Gül Özhan and Derya Dursun. “Antioxidant supplements: Positive or negative actors in orthodontic treatment.” İstanbul Journal of Pharmacy, vol. 53, no. 3, 2023, pp. 358-367. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2023.1329006


Vancouver

Bilici Geçer R, Özhan G, Dursun D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy [Internet]. 28 Apr. 2024 [cited 28 Apr. 2024];53(3):358-367. Available from: https://doi.org/10.26650/IstanbulJPharm.2023.1329006 doi: 10.26650/IstanbulJPharm.2023.1329006


ISNAD

Bilici Geçer, Rümeysa - Özhan, Gül - Dursun, Derya. “Antioxidant supplements: Positive or negative actors in orthodontic treatment”. İstanbul Journal of Pharmacy 53/3 (Apr. 2024): 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006



TIMELINE


Submitted18.07.2023
Accepted21.08.2023
Published Online03.10.2023

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