Research Article


DOI :10.26650/IstanbulJPharm.2018.180003   IUP :10.26650/IstanbulJPharm.2018.180003    Full Text (PDF)

Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

Muhammad Zakariyyah AumeeruddyZaahira Aumeeruddy ElalfiHudaa NeetooGökhan ZenginBianca FibrichSunelle RademanAnalike Blom Van StadenKarina SzumanIsa Anina LambrechtsNamrita LallMohamad Fawzi Mahomoodally

This study was designed to evaluate and correlate the biological, phytochemical, and physicochemical properties of two NSS (Nigella sativa seed) oils (N1 and N2). The biological activity was evaluated in terms of antibacterial, antioxidant (nitric oxide scavenging), antielastase, antityrosinase, antimelanogenic, and anticancer activity. Physicochemical properties including colour, total soluble solids (TSS), and density were also investigated. N2 exhibited higher antibacterial, NO scavenging, extracellular antimelanogenic, and anticancer activity against the HeLa cell line compared to N1, which showed higher antityrosinase activity. TPC (total phenolic content) and TFC (total flavonoid content) of N1 were significantly higher than N2 while TTC (total tannin content) was higher in N2. In fact, TTC was strongly correlated (R=1.000) with the antioxidant, extracellular antimelanogenic, and HeLa cell inhibitory activity. To conclude, NSS oil may be considered as a complementary and alternative therapy in the management of infectious and chronic diseases but warrants further in vivo pharmacological validation and toxicological analysis.


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APA

Aumeeruddy, M., Aumeeruddy Elalfi, Z., Neetoo, H., Zengin, G., Fibrich, B., Rademan, S., Blom Van Staden, A., Szuman, K., Lambrechts, I., Lall, N., & Mahomoodally, M. (2018). Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy, 48(3), 89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003


AMA

Aumeeruddy M, Aumeeruddy Elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Blom Van Staden A, Szuman K, Lambrechts I, Lall N, Mahomoodally M. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy. 2018;48(3):89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003


ABNT

Aumeeruddy, M.; Aumeeruddy Elalfi, Z.; Neetoo, H.; Zengin, G.; Fibrich, B.; Rademan, S.; Blom Van Staden, A.; Szuman, K.; Lambrechts, I.; Lall, N.; Mahomoodally, M. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy, [Publisher Location], v. 48, n. 3, p. 89-99, 2018.


Chicago: Author-Date Style

Aumeeruddy, Muhammad Zakariyyah, and Zaahira Aumeeruddy Elalfi and Hudaa Neetoo and Gökhan Zengin and Bianca Fibrich and Sunelle Rademan and Analike Blom Van Staden and Karina Szuman and Isa Anina Lambrechts and Namrita Lall and Mohamad Fawzi Mahomoodally. 2018. “Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis.” İstanbul Journal of Pharmacy 48, no. 3: 89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003


Chicago: Humanities Style

Aumeeruddy, Muhammad Zakariyyah, and Zaahira Aumeeruddy Elalfi and Hudaa Neetoo and Gökhan Zengin and Bianca Fibrich and Sunelle Rademan and Analike Blom Van Staden and Karina Szuman and Isa Anina Lambrechts and Namrita Lall and Mohamad Fawzi Mahomoodally. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis.” İstanbul Journal of Pharmacy 48, no. 3 (Jun. 2025): 89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003


Harvard: Australian Style

Aumeeruddy, M & Aumeeruddy Elalfi, Z & Neetoo, H & Zengin, G & Fibrich, B & Rademan, S & Blom Van Staden, A & Szuman, K & Lambrechts, I & Lall, N & Mahomoodally, M 2018, 'Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis', İstanbul Journal of Pharmacy, vol. 48, no. 3, pp. 89-99, viewed 5 Jun. 2025, https://doi.org/10.26650/IstanbulJPharm.2018.180003


Harvard: Author-Date Style

Aumeeruddy, M. and Aumeeruddy Elalfi, Z. and Neetoo, H. and Zengin, G. and Fibrich, B. and Rademan, S. and Blom Van Staden, A. and Szuman, K. and Lambrechts, I. and Lall, N. and Mahomoodally, M. (2018) ‘Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis’, İstanbul Journal of Pharmacy, 48(3), pp. 89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003 (5 Jun. 2025).


MLA

Aumeeruddy, Muhammad Zakariyyah, and Zaahira Aumeeruddy Elalfi and Hudaa Neetoo and Gökhan Zengin and Bianca Fibrich and Sunelle Rademan and Analike Blom Van Staden and Karina Szuman and Isa Anina Lambrechts and Namrita Lall and Mohamad Fawzi Mahomoodally. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis.” İstanbul Journal of Pharmacy, vol. 48, no. 3, 2018, pp. 89-99. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2018.180003


Vancouver

Aumeeruddy M, Aumeeruddy Elalfi Z, Neetoo H, Zengin G, Fibrich B, Rademan S, Blom Van Staden A, Szuman K, Lambrechts I, Lall N, Mahomoodally M. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. İstanbul Journal of Pharmacy [Internet]. 5 Jun. 2025 [cited 5 Jun. 2025];48(3):89-99. Available from: https://doi.org/10.26650/IstanbulJPharm.2018.180003 doi: 10.26650/IstanbulJPharm.2018.180003


ISNAD

Aumeeruddy, Muhammad Zakariyyah - Aumeeruddy Elalfi, Zaahira - Neetoo, Hudaa - Zengin, Gökhan - Fibrich, Bianca - Rademan, Sunelle - Blom Van Staden, Analike - Szuman, Karina - Lambrechts, Isa Anina - Lall, Namrita - Mahomoodally, Mohamad Fawzi. Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis”. İstanbul Journal of Pharmacy 48/3 (Jun. 2025): 89-99. https://doi.org/10.26650/IstanbulJPharm.2018.180003



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Accepted03.12.2018

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