References

• Ahmed, A., Majeed, I.Y., Asaad, N., Ahmed, R.M., Kamil, G.M., & Rahman, S.S. (2022). Some 3,4,5-Trisubstituted-1,2,4-triazole Synthesis, Antimicrobial Activity, and Molecular Dock-ing Studies. Egyption Journal of Chemistry, 65(3):395-401. https://dx.doi.org/10.21608/ejchem.2021.93025.4397 google scholar
• Bakr, F., Abdel-Wahab, M.S., Bekheit, H.M., Mashaly, A.A., & Fahmy, H.M. (2023). Novel Dinitrophenylhydrazones Contain-ing 1,2,3-Triazole Nucleus as Disperse Dyes for Polyester Fab-ric Dyeing and Functional Finishing and Antibacterial Ac-tivities. Polycyclic Aromatic Compounds, 43(4): 3342-3352. https://doi.org/10.1080/10406638.2022.2068623 google scholar
• Benhammadi, S., Salimairaten, S., & Othman, A. (2016). Synthetic studies and antibacterial activity of nucleobases and their N-and S-glucosides from 2-amino benzoic acid and its benzamido derivatives. Oriental Journal of Chemistry, 32(5):2567-2576. http://dx.doi.org/10.13005/ojc/320528 google scholar
• Blank, B., Nichols, D.M., & Vaidya, P.D. (1972). Synthesis of 1,2,4-triazoles as potential hypoglycemic agents. Journal of Medicinal Chemistry, 15(6):694-696. https://doi.org/10.1021/jm00276a040 google scholar
• Cacic, M., Molnar, M., Sarkanj, B., Has-Schön, E., & Rajkovic, V. (2010). Synthesis and biological evaluation of some Schiff bases of [4-(amino) -5- phenyl- 4H-1, 2, 4-triazole- 3- thiol]. Molecules, 6795-6809. google scholar
• Cavusoglu, B., Yurttas, L., & Canturk, Z. (2018). The synthesis, anti-fungal and apoptotic effects of triazole-oxadiazoles against Can-dida species. European Journal of Medicinal Chemistry, 144: 255-261. https://doi.org/10.1016/j.ejmech.2017.12.020 google scholar
• Demirbas, N., Ugurluoglu, R., & Demirbas, A. (2002) Syn-thesis of 3-Alkyl(Aryl)-4-alkylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-ones and 3-Alkyl-4-alkylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones as Antitumor Agents. Bioorganic & Medic-inal Chemistry, 10:3717-3723. https://doi.org/10.1016/s0968-0896(02)00420-0 google scholar
• Desai, S.P., Momin, Y.H., Taralekar, S.T., Dange, Y.D., Jagtap, S.R. & Khade, H.P. (2021). Evaluation of potential in vitro anticancer and antimicrobial activities of synthesized 5-mercapto-4-substituted 1,2,4 triazole derivatives. Annals of Phytomedicine, 10(2): 273279. http://dx.doi.org/10.21276/ap.2021.10.2.36 google scholar
• Diogo, A.N., Bertrand, B., Thorimbert, S., Gontard, G., Kahn, S.N., Echeverri, A., & Contreras-Garrfa, J. (2023). 3-Hydroxypyridinyl-Substituted-1,2,4-Triazoles as New ESIPT Based Fluorescent Dyes: Synthesis and Structure-Fluorescence Properties Correlations. Advanced Optical Materials, 11:1-12. https://doi.org/10.1002/adom.202300336 google scholar
• ElBelghiti, M., Karzazi, Y., Dafali, A., Hammouti, B., Bentiss, F., Obot, I.B., Bahadur, I., & Ebenso, E.E. (2016). Experimen-tal, quantum chemical and Monte Carlo simulation studies of 3,5-disubstituted-4-amino-1,2,4-triazoles as corrosion inhibitors on mild steel in acidic medium. Journal of Molecular Liquids, 218:281-293. http://dx.doi.org/10.1016/j.molliq.2016.01.076 google scholar
• El-Essawy, F.A., El-Sayed, W.A., El-Kafrawy, S.A., Morshedy, A.S., & Abdel-Rahman, A.H.Z. (2008). Anti-hepatitis B virus activity of new 1,2,4-triazol-2- yl- and 1,3,4-oxadiazol-2-yl-2-pyridinone derivatives. Zeitschrift für Naturforschung C, 63:667-772. PMID:19040105 google scholar
• Fedotov, S.O., & Hotsulia, A.S. (2023). Synthesis and proper-ties of S-alkyl 4-amino-5-(5-(3-fluorophenyl)-pyrazol-3-yl)-1,2,4-triazole-3-thiol derivatives. Pharmacy and Medicine: Sci-ence and Practice, 16(1): 5-11. https://doi.org/10.14739/2409-2932.2023.1.273461 google scholar
• Fidler, D.P (1998). Legal Issues Associated with Antimicrobial Drug Resistance. Emerging Infectious Diseases, 4(2):169-177. https://doi.org/10.3201/eid0402.980204 google scholar
• Howatt, K.A. (2005). Carfentrazone ethyl injury to spring wheat (Triticum aestivum) is minimized by some ALS2 inhibiting herbicides 1. Weed Technology, 19: 777-783. http://dx.doi.org/10.1614/WT-04-206.1 google scholar
• Huntsman, E. & Balsells, J. (2005). New Method for the General Synthesis of [1,2,4]Triazolo[1,5-a]pyridines. European Journal of Organic Chemistry, 3761-3765. https://doi.org/10.1002/ejoc.200500247 google scholar
• Kane, J.M., Dudley, M.W., Sorensen, S.M., & Miller, F.P. (1988). 2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepres-sant Agents. Jounal of Medicinal Chemistry, 31(6):1253-1258. https://doi.org/10.1002/chin.198843203 google scholar
• Karabasanagouda, T., Adhikari, A.V., & Shetty, N.S. (2006). Synthesis and antimicrobial activities of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines carrying thioalkyl and sulphonyl phenoxy moi-eties. European Journal of Medicinal Chemistry, 42(4):521-529. https://doi.org/10.1016/j.ejmech.2006.10.010 google scholar
• Karpun, Ye., & Polishchuk, N. (2021). Synthesis and antimi-crobial activity of s-substituted derivatives of 1,2,4-triazol-3-thiol. ScienceRise: Pharmaceutical Science, 3(31): 64-69. doi: http://doi.org/10.15587/2519-4852.2021.235976 google scholar
• Kazeminejad, Z., Marzi M., Shiroudi, A., Kouhpayeh, S.A., Farjam, M., & Zarenezhad, E. (2022). Novel 1, 2, 4-Triazoles as Anti-fungal Agents. BioMed Research International, 4584846, 1-39. https://doi.org/10.1155/2022/4584846 google scholar
• Klimesova, V., Zahajska, L., Waisser, K., Kaustova, J., & Moll-mann, U. (2004). Synthesis and antimycobacterial activity of 1,2,4-triazole-3-benzylsulfanyl derivatives. Il Farmaco, 59:279-288. https://doi.org/10.1016/j.farmac.2004.01.006 google scholar
• Koparir, P., Parlak, A.E., Karatepe, A., & Omar, R.A. (2022). Elucida-tion of potential anticancer, antioxidant and antimicrobial proper-ties of some new triazole compounds bearing pyridine-4-yl moi-ety and cyclobutane ring. Arabian Journal of Chemistry, 15:1-10. https://doi.org/10.1016/j.arabjc.2022.103957 google scholar
• Kumari, M., Tahlan, S., Narasimhan, B., Ramasamy, K., Meng, S., Shah, S.A.A., Mani, V., & Kakkar, S. (2021). Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents. BMC Chemistry, 15(5):1-16. https://doi.org/10.1186/s13065-020-00717-y google scholar
• Küçükgüzel, I., Güniz, S.K., Rollas, S., Otük-Saniş, G., Ozdemir, O., Bayrak, I., Altuğ, T., & Stables, J.P. (2004). Synthesis of some 3-(arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole derivatives and their anticonvulsant activity. Il Farmaco, 59(11):893-901. https://doi.org/10.1016/j.farmac.2004.07.005. google scholar
• Li, D., He, M., Chen, B., & Hu, B. (2019). Mag-netic porous organic polymers for magnetic solid-phase extraction of triazole fungicides in vegetables prior to their determination by gas chromatography-flame ioniza-tion detection. Journal of Chromatography A, 1601: 1-8. https://doi.org/10.1016/j.chroma.2019.04.062 google scholar
• Li, N., Guan, Q., Hong, Y., Zhang, B., Li, M., Li, X., Li, B., Wu, L. & Zhang, W. (2023). Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4] triazoles as potent tubulin polymerization inhibitors. European Journal of Medicinal Chemistry, 56:1-13.https://doi.org/10.1016/j.ejmech.2023.115402 google scholar
• Liu, G., Tian, M., Lu, M., Shi, W., Li, L., Gao, Y., Li, T., & Xu, D. (2021). Preparation of magnetic MOFs for use as a solid-phase extraction absorbent for rapid adsorption of triazole pesticide residues in fruits juices and vegetables. Journal of Chromatography B 1166:122500. https://doi.org/10.1016/j.jchromb.2020.122500 google scholar
• Ma, Q.-C., Yue, T.-C., Cao, Q.-W., Xie, Z.-B., Dong, Q.-W., & Wang, D.-Z. (2023). Study on magnetic and dye adsorption properties of five coordination polymers based on triazole car-boxylic acid ligands. Journal of Molecular Structure, 1284:1-9. https://doi.org/10.1016/j.molstruc.2023.135379 google scholar
• Mohamed, N.G., Sheha, M.M., Hassan, H.Y., Abdel-Hafez, L.J.M., & Omar, F.A. (2018). Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1, 2, 4-triazol-3-yl]-naphthyridinones as potential google scholar
• DNA-gyrase inhibitors. Bioorganic Chemistry, 81: 599-611. https://doi.org/10.1016/j.bioorg.2018.08.031 google scholar
• Mullican, M.D., Wilson, M.W., Conner, D.T., Kostlan, C.R., Schrier, D.J., & Dyer, R.D. (1993). Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles,-1,3,4-oxadiazoles and -1,2,4-triazoles as orally active, nonulcerogenic antiinflammatory agents. Journal of Medicinal Chemistry, 36(8):1090-1099. https://doi.org/10.1021/jm00060a017 google scholar
• Nazarov, V., Miroshnichenko, D., Ivakh, O., & Pyshyev, S. (2023). State of the Art in Industrial Application of Amino-1,2,4-Triazoles. Mini-Reviews in Organic Chemistry, 20(4):394-402. http://dx.doi.org/10.2174/1570193X19666220331155015 google scholar
• Popiolek, L., Paruch, K., Patrejko, P., Biernasiuk, A., & Wujec, M. (2016). New 3-hydroxy-2-naphthoic hydrazide derivatives: thiosemicarbazides and 1,2,4-triazole-3-thiones, their synthesis and in vitro antimicrobial evaluation. Journal ofthe Iranian Chem-ical Society, 13:1945-1951. http://dx.doi.org/10.1007/s13738-016-0911-1 google scholar
• Popova, L., Ivanchenko, O., Njanikova, G., Vershilov, S., Suchilova, V., & Gaurav, B. (2021). Perfluorosubstituted Derivatives of 1,3-Diazine and 1,2,4-Triazole as a Means of Protecting Industrial Structures from Microbiologically Induced Corrosion. In: Vatin, N., Borodinecs, A., Teltayev, B. (eds) Proceedings of EECE 2020. EECE 2020. Lecture Notes in Civil Engineering, vol 150. Springer, Cham. https://doi.org/10.1007/978-3-030-72404-7_5 google scholar
• Sameliuk, Y.G., Zedan, F.A., & Kaplaushenko, T.M. (2021). 1,2,4-Triazole Derivatives In Medicine And Pharmacy And Application Prospects. Journal of Faculty of Pharmacy of Ankara University, 45(3): 598-614. htps://doi.org/10.33483/jfpau.885888 google scholar
• Seebunrueng, K., Tamuang, S., Ruangchai, S., Sansuk, S., & Sri-jaranai, S. (2021). In situ self-assembled coating of surfactant-mixed metal hydroxide on Fe3 O4 @SiO2 magnetic composite for dispersive solid phase micro extraction prior to HPLC analy-sis of triazole fungicides. Microchemical Journal, 168: 106396 https://doi.org/10.1016/j.microc.2021.106396 google scholar
• Sekhar, M.M., Nagarjuna, U., Padmavathi, V., Padmaja, A., Vasudeva, N.R., & Vijaya, T. (2018). Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles. European Journal of Medicinal Chemistry, 145:1-10. https://doi.org/10.1016/j.ejmech.2017.12.067 google scholar
• Selvaraj, J., Pranabesh, S., Shanish, A., Rajagopal, K., Byran, G., Subramanian, G., & Kannan, E. (2011). Synthesis And Biolog-ical Evaluaiıon of Some Schiff Bases of [4-(Amino)-5- Phenyl-4h-1,2,4-Trıazole-3-Thıol]Ring terming Polymerisation, Part-B-1. google scholar
• Pakistan Journal of Pharmaceutical Sciences, 24(2):109-112. google scholar
• Shah, M.H., Mhasalkar, M.Y., Patki, V.M., Deliwala, C.V., & Sheth, U.K. (1969). New 1,2,4(H)-Triazole Derivatives as Di-uretic Agents. Journal of Pharmaceutical Sciences, 58(2):1399. https://doi.org/10.1002/jps.2600581123 google scholar
• Shang, J., Wang, W.M., Li, Y.H., Song, H.B., Li, Z.M., & Wang, J.G. (2012). Synthesis, crystal structure, in vitro acetohydroxyacid synthase inhibition, in vivo herbicidal activity, and 3D-QSAR of new asymmetric aryl disulfides. Jounal of Agricultural and Food Chemistry, 29(34):8286-8293. https://doi.org/10.1021/jf302206x google scholar
• Shcherbyna, R., Pruhlo, Y., Duchenko, M., Kulagina, M., Kudria, V., & Vashchuk Valentyna, V. (2022). Evaluation of Antioxi-dant Activity of 1,2,4-Triazole Derivatives With Morpholine Moi-ety. Hacettepe University Journal of the Faculty of Pharmacy, 42(2):73-82. https://doi.org/10.52794/hujpharm.1033112 google scholar
• Shevtsov, D.S., Shikhaliev, Kh.S., Stolpovskaya, N.W., Kruzhilin, A.A., Potapov, A.Yu., Zartsyn, I.D., Kozaderov, O.A., Lyapun, D.V., Prabhakar, C., & Tripathi, A. (2020). 3-Alkyl-5-amino-1,2,4-triazoles synthesized from the fatty acids of sunflower oil processing waste as corrosion inhibitors for copper in chloride en-vironments. International Journal of Corrosion and Scale Inhibi-tion, 9(2):726-744. https://dx.doi.org/10.17675/2305-6894-2020-9-2-21 google scholar
• Shimada, Y., Ito, T., Maeta, H., Matsuoka, K. & Sato, K. (2006). A Novel Heterocyclic Cyan Dyeforming Coupler for Color Photo-graphic Use: Synthesis of 1H-Pyrrolo [ 1,2-b] [1, 2, 4]triazole. Journal of Synthetic Organic Chemistry, 64(3): 222-226. google scholar
• Sloop, J. (2023). Synthesis of Heteroaromatic Compounds. Molecules, 28:1-4. https://doi.org/10.3390/molecules28083563 google scholar
• Sobhi, M.G., Mastoura, M.E., Zeinab, A.M., Nabila, A.K., Sraa, A.M. & Amirah, M.S. (2022) Synthesis, Characterization, and An-timicrobial Evaluation of Some New 1,4-Dihydropyridines-1,2,4-Triazole Hybrid Compounds. Polycyclic Aromatic Compounds, 42(1):173-185. https://doi.org/10.1080/10406638.2020.1720751 google scholar
• Subhas, S., Sindhu, K.N., & Sreeveena, K. (2019). The Signifi-cance of 1, 2, 4 Triazoles in Agriculture Science: A Review Re-search Journal of Pharmacy and Technology, 12(10):5091- 5071. http://dx.doi.org/10.5958/0974-360X.2019.00882.5 google scholar
• Sztanke, K., Pasternak, K., Rzymowska, J., Sztanke, M., & Kandefer-Szerszen, M. (2008). Synthesis, structure elucidation and identi-fication of antitumoural properties of novel fused 1,2,4-triazine aryl derivatives. European Journal of Medicinal Chemistry, 43(5):1085-1094. https://doi.org/10.1016/j.ejmech.2007.07.009 google scholar
• Tozkoparan, B., Kupeli, E., Ozalp, S., & Ertan, M. (2005). Synthe-sis and evaluation of analgesic/antiinflammatory and antimicro-bial activities of 3-substituted-1,2,4-triazole-5- thiones. Arzneim-Forsch/Drug Research, 55(9): 533-540. https://doi.org/10.1055/s-0031-1296901 google scholar
• Tkach, V.V, Kushnir, M.V., Oliveira, S.C., Shevchenko, I.M., Odyntsova, V.M., Omelyanchik, V.M.... Vaz dos Reis, L. google scholar
• (2023). Theoretical Description for Anti-COVID-19 Drug Mol-nupiravir Electrochemical Determination over the Poly-((1,2,4-triazole)-co-(squaraine dye) Composite with Cobalt (III) Oxyhy-droxide. Biointerface Research in Applied Chemistry 13(1): 74-80. https://biointerfaceresearch.com/ google scholar
• Ueda, S., & Nagasawa, H. (2009). Facile Synthesis of 1,2,4-Triazoles via a Copper-Catalyzed Tandem Addition-Oxidative Cyclization. Journal of the American Chemical Society, 131(42):15080-15081. https://doi.org/10.1021/ja905056z google scholar
• Vagish, C.B., Sudeep, P., Jayadevappa, H.P. & Ajay Kumar, K. (2020). 1,2,4-Triazoles: synthetic and medicinal perspectives. In-ternational Journal of Current Research, 12(08): 12950-12960.https://doi.org/10.24941/ijcr.39386.08.2020 google scholar
• Valicsek, V.-S., & Badea, V. (2021). (R,S)-2-[4-(4-Methylphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]thio-1-phenyl-1-ethanol. Molbank, 2021, M1241. https://doi.org/10.3390/M1241 google scholar
• Wang, Y., He, M., Chen, B., & Hu, B. (2020). Hydroxyl-containing porous organic framework coated stir arsorption extraction com-bined with high performance liquid chromatography-diode ar-ray detector for analysis of triazole fungicides in grape and cabbage samples. Journal of Chromatography A 1633 461628 https://doi.org/10.1016/j.chroma.2020.461628 google scholar
• Wright, W.B.Jr., Press, J.B., Chan, P.S., Marsico, J.W., Haug, M.F., Lucas, J., Tauber, J., & Tomcufcik, A.S. (1986). Thrombox-ane synthetase inhibitors and antihypertensive agents. 1. N-[(1H-imidazol-1-yl)alkyl]aryl amides and N-[(1H-1,2,4-triazol-1-yl)alkyl]aryl amides. Journal of Medicinal Chemistry, 29(4):523-530. https://doi.org/10.1021/jm00154a017 google scholar
• Wu, J., Ni, T., Chai, X., Wang, T., Wang, H.... Jiang,Y. (2018). Molecular docking, design, synthesis and an-tifungal activity study of novel triazole derivatives. Eu-ropean Journal of Medicinal Chemistry 143: 1840-1846. https://doi.org/10.1016/j.ejmech.2017.10.081 google scholar
• Xie, F., Ni, T., Zhao, J., Pang, L., Li, R.... Jiang, Y. (2017). De-sign, synthesis, and in vitro evaluation of novel antifungal tria-zoles. Bioorganic & Medicinal Chemistry Letters, 27: 2171-2173. https://doi.org/10.1016/j.bmcl.2017.03.062 google scholar
• Y an, T., Jinchao, M., Yang, H., & Cheng, G. (2022). Introduction of energetic bis-1,2,4-triazoles bridges: A strategy towards ad-vanced heat resistant explosives. Chemical Engineering Journal, 429:132416. https://doi.org/10.1016/j.cej.2021.132416 google scholar
• Y ang, B., He, Q.J., & Zhu, D.Y. (2006). Antiproliferative activity of contragestazol (DL1112IT) in murine and human tumor models in vitro and in vivo. Cancer Chemotherapy and Pharmacology, 57: 268-273. https://doi.org/10.1007/s00280-005-0049-9 google scholar
• Y eung, K.S., & Farkas, M.E. (2005). A base-catalyzed, di-rect synthesis of 3,5-disubstituted 1,2,4-triazoles from ni-triles and hydrazides. Tetrahedron Letters, 46(19):3429-3432. https://doi.org/10.1016/j.tetlet.2005.02.167 google scholar
• Yin, P., Ma, W.B., Chen, Y., Huang, W.C., Deng, Y., & He, L. (2009). Highly efficient cyanoimidation of aldehydes. Organic Letters, 3(23):5482-5485. https://doi.org/10.1021/ol902207h google scholar
• Youichiro, N., Akahoshi, F., Takeda, S., Okada, T., Kajii, M., Nishimura, H., Sugiura, M., Fukaya, C., & Kagitani, Y. (1996). Synthesis and Pharmacological Activity of Triazole Deriva-tives Inhibiting Eosinophilia. Journal of Medicinal Chemistry, 39:3019-3029. https://doi.org/10.1021/jm9507993 google scholar
• Zazharskyi, V., Bigdan, O., Parchenko, V., Parchenko, M., Fotina, T., Davydenko, P.... Borovik, I. (2021). Antimicrobial Activity of google scholar
• Some Furans Containing 1,2,4-Triazoles. Archives of Pharmacy Practice, 12(2):60-5. https://doi.org/10.51847/RbJb3waUBB google scholar
• Zhang, H.Z., Damu, G.L.V., Cai, G.X., & Zhou, C.H. (2014). Current Developments in the Syntheses of 1,2,4-Triazole Compounds. Current Organic Chemistry, 18:359-406. https://doi.org/10.2174/13852728113179990025 google scholar
• Zhou, H.C. & Wang, Y. (2012). Recent researches in triazole compounds as medicinal drugs. Current Medicinal Chemistry, 19(2):239-280. https://doi.org/10.2174/092986712803414213 google scholar
• Zveaghintseva, M., Stingaci, E., Pogrebnoi, S., Smetanscaia, A., Valica, V., Uncu, L. ... Macaev, F.Z. (2021). Chromenol derivatives as novel antifungal agents: synthe-sis, in silico and in vitro evaluation. Molecules, 26(14):1-21. https://doi.org/10.3390/molecules26144304 google scholar

Citations