Journal of Advanced Research in Health Sciences

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DOI :10.26650/JARHS2020-S1-0011   IUP :10.26650/JARHS2020-S1-0011    Full Text (PDF)

COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs

Fatoş İlkay Alp Yıldırım, Meryem Sedef Erdal

On 31st December 2019, World Health Organization (WHO) Country Office in China reported pneumonia cases of unknown etiology in Wuhan in the Hubei province of the Republic of China. It is reported that a novel coronavirus 2019 (2019-nCoV), has not been previously identified in humans, causes the infectious disease, known as COVID-19. 2019-nCoV virus renamed as SARS-CoV-2 virus which is genetically similar to the SARS Coronavirus of 2002, SARS-CoV-1. As of April 2020 approxy3 million people confirmed as COVID-19 positive, globally. Based on preclinical evidences and/or limited clinical reports, it is hypothesised that some pharmacological agents, including Ibuprofen, a Non-steroidal antiinflammatory drug, increase the risk of onset anddeveloping severe COVID-19, and exacerbate the symptoms in patients. More definite evidence from laboratory and clinical research is needed for further progress in order enlighten this issue. 

Keywords: SARS-CoV-2, COVID-19, NSAID, Ibuprofen, rational drug use
DOI :10.26650/JARHS2020-S1-0011   IUP :10.26650/JARHS2020-S1-0011    Full Text (PDF)

COVID-19 Sürecinde İbuprofen ve Diğer Nonsteroidal Antienflamatuvar İlaçların Kullanımının Güvenirliliği

Fatoş İlkay Alp Yıldırım, Meryem Sedef Erdal

Dünya Sağlık Örgütü (DSÖ) Çin Ülke Ofisi 31 Aralık 2019'da Çin'in Hubei eyaletinin Wuhan şehrinde etiyolojisi bilinmeyen pnömoni vakaları bildirmiştir. Bu vakaların etkeninin, daha önce insanlarda tespit edilmemiş yeni bir Coronavirus (2019-nCoV) olduğu saptanmıştır. Söz konusu virüs, 2002 yılındaki SARS enfeksiyon etkeni SARS CoV-1 virüse yakın genetik benzerliğinden dolayı SARS-CoV-2 olarak adlandırılmış, hastalığın adı da COVID-19 olarak kabul edilmiştir. Nisan 2020 itibari ile dünya üzerinde yaklaşık 3.000.000 COVID-19 vakası tespit edilmiştir. Farklı hastalıkların tedavisi için akut ya da kronik olarak kullanılan bazı ilaçların COVID-19 enfeksiyonuna duyarlılık açısından bir risk faktörü olabileceği ve/ veya COVID-19 hastalığının seyri üzerinde olumsuz etkilere sahip olabileceği yönündeki preklinik bulgular ya da hipotez düzeyindeki öneriler bu ilaçları kullanan kişilerde tedirginlik yaratmıştır. Bahsi geçen ilaçlar arasında, non-steroidal Antienflamatuvar grubu bir ilaç olan İbuprofen de yer almıştır. COVID-19 enfeksiyon etkenine duyarlılığı arttırdığı ve/ veya COVID-19 hastalığının seyri üzerinde olumsuz etkilere sahip olabileceği iddia edilen ilaçların klinik açıdan dikkatle değerlendirilmesi ve yeterli bilimsel kanıtlar çerçevesinde olaya netlik kazandırılması son derece önemlidir.

Keywords: SARS-CoV-2, COVID-19, NSAII, Ibuprofen, akılcı ilaç kullanımı

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Citations

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APA

Alp Yıldırım, F.İ., & Erdal, M.S. (2020). COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs. Journal of Advanced Research in Health Sciences, 3(1), 88-91. https://doi.org/10.26650/JARHS2020-S1-0011


AMA

Alp Yıldırım F İ, Erdal M S. COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs. Journal of Advanced Research in Health Sciences. 2020;3(1):88-91. https://doi.org/10.26650/JARHS2020-S1-0011


ABNT

Alp Yıldırım, F.İ.; Erdal, M.S. COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 3, n. 1, p. 88-91, 2020.


Chicago: Author-Date Style

Alp Yıldırım, Fatoş İlkay, and Meryem Sedef Erdal. 2020. “COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs.” Journal of Advanced Research in Health Sciences 3, no. 1: 88-91. https://doi.org/10.26650/JARHS2020-S1-0011


Chicago: Humanities Style

Alp Yıldırım, Fatoş İlkay, and Meryem Sedef Erdal. “COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs.” Journal of Advanced Research in Health Sciences 3, no. 1 (Apr. 2024): 88-91. https://doi.org/10.26650/JARHS2020-S1-0011


Harvard: Australian Style

Alp Yıldırım, Fİ & Erdal, MS 2020, 'COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs', Journal of Advanced Research in Health Sciences, vol. 3, no. 1, pp. 88-91, viewed 27 Apr. 2024, https://doi.org/10.26650/JARHS2020-S1-0011


Harvard: Author-Date Style

Alp Yıldırım, F.İ. and Erdal, M.S. (2020) ‘COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs’, Journal of Advanced Research in Health Sciences, 3(1), pp. 88-91. https://doi.org/10.26650/JARHS2020-S1-0011 (27 Apr. 2024).


MLA

Alp Yıldırım, Fatoş İlkay, and Meryem Sedef Erdal. “COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs.” Journal of Advanced Research in Health Sciences, vol. 3, no. 1, 2020, pp. 88-91. [Database Container], https://doi.org/10.26650/JARHS2020-S1-0011


Vancouver

Alp Yıldırım Fİ, Erdal MS. COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs. Journal of Advanced Research in Health Sciences [Internet]. 27 Apr. 2024 [cited 27 Apr. 2024];3(1):88-91. Available from: https://doi.org/10.26650/JARHS2020-S1-0011 doi: 10.26650/JARHS2020-S1-0011


ISNAD

Alp Yıldırım, Fatoşİlkay - Erdal, MeryemSedef. “COVID-19 and Safety of Ibuprofen and Other a Non-steroidal Antiinflammatory Drugs”. Journal of Advanced Research in Health Sciences 3/1 (Apr. 2024): 88-91. https://doi.org/10.26650/JARHS2020-S1-0011



TIMELINE


Submitted24.04.2020
Accepted29.05.2020
Published Online15.05.2020

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