Review Article


DOI :10.26650/JARHS2025-1552555   IUP :10.26650/JARHS2025-1552555    Full Text (PDF)

PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER

Fatma Betül Çakır

Children with cancer experience severe adverse effects from cancer or as a sequela of cancer treatment. These side effects can affect major body systems such as musculoskeletal, cardiovascular and neurological systems and impact participation in daily living activities and thus quality of life. These sequelae are to be lessened with physical therapy, rehabilitation, or neuropsychological treatment according to the requirements of the patients. Thus, awareness of the rehabilitation needs of children with cancer is crucial to enhance a healthy life with quality. Recommendations concerning the quality of life among adults are included in the guidelines, but data including recommendations for children are limited.

DOI :10.26650/JARHS2025-1552555   IUP :10.26650/JARHS2025-1552555    Full Text (PDF)

KANSERLİ ÇOCUK HASTALARDA FİZİKSEL AKTİVİTE GİRİŞİMLERİ

Fatma Betül Çakır

Kanserli çocuklar, kanserin veya hastalığın tedavisinden kaynaklanan ciddi yan etkiler ve sekeller yaşamaktadır. Bu yan etkiler, en majör vücut sistemlerinden olan iskelet-kas, kalp ve solunum ile nörolojik sistemleri etkileyerek hastanın günlük yaşam aktivitelerini engellemekte ve hayat kalitesini bozmaktadır. Bu engellenmeler hastanın gerektirdiği her türlü fiziksel aktivite, rehabilitasyon ve nöropsikolojik tedaviler ile en aza indirilmeye çalışılmaktadır. Bu nedenle, kanserli çocuklarda rehabilitasyon ihtiyacının farkedilmesi kaliteli bir hayat için şarttır. Erişkinlerin hayat kalitesi için yapılan öneriler kılavuzlara dönüştürülmüş olmasına rağmen çocuk hastalar için öneriler halen kısıtlıdır. 


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References

  • Ospina PA, McComb A, Pritchard-Wiart LE, Eisenstat DD, McNeely ML. Physical therapy interventions, other than general physical exercise interventions in children and adolescents before, during and following treatment for cancer. Cochrane Database Syst Rev 2021;8(8):CD012924. google scholar
  • Skinner R. Long-term effects of cancer therapy in children - functional effects, late mortality and long-term follow-up. Paediatrics and Child Health 2012;22(6):248-52. google scholar
  • National Cancer Institute. Late effects of treatment for childhood Cancer (PDQ®) - patient version. www.cancer.gov/types/ childhood-cancers/late-eDects-pdq accessed 15 September 2024). google scholar
  • Children’s Oncology Group (COG). Long-Term Follow-Up Guidelines for Survivors of Childhood Adolescent and Young Adult Cancers. Version 5.0. COG; 2018. Accessed September 15, 2024. http:// www.survivorshipguidelines.org/pdf/2018/COG_LTFU_ Guidelines_v5.pdf google scholar
  • Rossi F, Ricci F, Botti S, Bertin D, Breggie S, Casalaz R, et al. The Italian consensus conference on the role of rehabilitation for children and adolescents with leukemia, central nervous system, and bone tumors, part 1: review of the conference and presentation of consensus statements on rehabilitative evaluation of motor aspects. Pediatr Blood Cancer 2020;67(12):e28681. google scholar
  • Rossi F, Botti S, Morri M, Asaftei S, Bertin D, Breggie S, et al. The Italian consensus conference on the role of rehabilitation for children and adolescents with leukemia, central nervous system, and bone tumors, part 2:general principles for the rehabilitation treatment of motor function impairments. Pediatr Hematol Oncol 2024;41(5):346-66. google scholar
  • Lavoie Smith EM, Li L, Chiang C, Thomas K, Hutchinson RJ, Wells EM, et al. Patterns and severity of vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia. J Peripher Nerv Syst 2015;20(1):37-46. google scholar
  • Tay CG, Lee VWM, Ong LC, Goh KJ, Ariffin H, Fong CY. Vincristine induced peripheral neuropathy in survivors of childhood acute lymphoblastic leukaemia. Pediatr Blood Cancer 2017;64(8):e26471. google scholar
  • Gurney JG, Kaste SC, Liu W, Srivastava DK, Chemaitilly W, Ness KK, et al. Bone mineral density among long term survivors of childhood acute lymphoblastic leukemia: results from the St. Jude Lifetime Cohort Study. Pediatr Blood Cancer 2014;61(7):1270-6. google scholar
  • Riccio I, Pota E,Marcarelli M, Affinita MC, Di Pinto D, Indolfi C, et al. Osteonecrosis as a complication in pediatric patients with acute lymphoblastic leukemia. PediatrMed Chir 2016;38(3):118. google scholar
  • Kizilocak H, Okcu F. Late effects of therapy in childhood acute lymphoblastic leukemia survivors. Turk J Haematol 2019;36(1):1-11. google scholar
  • Lipshultz SE, Colan SD, Gelber RD, Perez-Atayde AR, Sallan SE, Sanders SP. Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med 1991;324(12):808-15. google scholar
  • Fountain DM, Burke GAA. Multidisciplinary rehabilitation for children with brain tumors: a systematic review. Dev Neurorehabil 2017;20(2):68-75. google scholar
  • Tanrıverdi, M., Mutluay, F.K. & Çakır, F.B. Video-based exergaming versus conventional rehabilitation on balance in pediatric brain tumor survivors: a randomized clinical trial. Virtual Reality 2024;28:94. google scholar
  • Tanriverdi M, Cakir FB, Karantay Mutluay F. Efficacy of a virtual reality-based intervention in children with medulloblastoma: case series. An Pediatr (Engl Ed) 2023;98(1):62-5. google scholar
  • Escalas C, Bourdet C, Fayech C, Demoor-Goldschmidt C. [Long-term effects of radiation on the spine: results of a cohort of symptomatic survivors of childhood and review of the literature]. Bull Cancer 2015;102(7-8):684-90. google scholar
  • Braam KI, van der Torre P, Takken T, Veening MA, van Dulmen-den Broeder E, Kaspers GJ. Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. Cochrane Database Syst Rev 2016;3:CD008796. google scholar
  • Zucchetti G, Rossi F, Chamorro Vina C, Bertorello N, Fagioli F. Exercise program for children and adolescents with leukemia and lymphoma during treatment: a comprehensive review. Pediatr Blood Cancer 2018;65(5):e26924. google scholar
  • Tanir MK, Kuguoglu S. Impact of exercise on lower activity levels in children with acute lymphoblastic leukemia: a randomized controlled trial from Turkey. Rehabil Nurs 2013; 38(1):48-59. google scholar
  • Ruiz JR, Fleck SJ, Vingren JL, Ramirez M, Madero L, Fragala MS, et al. Preliminary findings of a 4-month intrahospital exercise training intervention on IGFs and IGFBPs in children with leukemia. J Strength Cond Res 2010;24(5):1292-7. google scholar
  • Jarden M, Adamsen L, Kjeldsen L, Birgens H, Tolver A, Christensen JF, et al. The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management. Leuk Res 2013;37(2):155-61. google scholar
  • Baumann FT, Bloch W, Beulertz J. Clinical exercise interventions in pediatric oncology: a systematic review. Pediatr Res 2013;74(4):366-74. google scholar
  • Jones LC, Kaste SC, Karol SE, DeFeo B, Kim HKW, Neel MD, et al. Team approach: Management of osteonecrosis in chil-dren with acute lymphoblastic leukemia. Pediatr Blood Cancer 2020;67(11):e28509. google scholar
  • Szulc-Lerch KU, Timmons BW, Bouffet E, Laughlin S, de Medeiros C, Skocic J, et al. Repairing the brain with physical exercise: Cortical thickness and brain volume increases in long-term pediatric brain tumor survivors in response to a structured exercise intervention. Neuroimage Clin 2018;518:972-85. google scholar
  • Benedetti MG, Erfe Delayon S, Colangeli M, Parisini F, Ferrari S, Manfrini M, et al. Rehabilitation needs in oncological patients: the On-rehab project results on patients operated for musculoskeletal tumors. Eur J Phys Rehabil Med 2017;53(1):81-90. google scholar
  • Shehadeh A, El Dahleh M, Salem A, Sarhan Y, Sultan I, Henshaw RM, et al. Standardization of rehabilitation after limb salvage surgery for sarcomas improves patients’ outcome. Hematol Oncol Stem Cell Ther 2013;6(3-4):105-11. google scholar
  • Lopresti M, Rancati J, Farina E, Bastoni S, Bernabe B, Succetti T, et al. Rehabilitation pathway after knee arthroplasty with mega prosthesis in osteosarcoma. Recenti Prog Med 2015; 106(8):385-92. google scholar
  • Morales JS, Valenzuela PL, Rincon-Castanedo C, Takken T, Fiuza-Luces C, Santos-Lozano A, et al. Exercise training in childhood cancer: A systematic review and meta-analysis of randomized controlled trials. Cancer Treat Rev 2018;70:154-67. google scholar
  • Müller C, Rosenbaum D, Krauth KA. Prospective evaluation of postural control and gait in pediatric patients with cancer after a 4-week inpatient rehabilitation program. Am J Phys Med Rehabil 2017;96(9):646—53. google scholar
  • Rossi F, Coppo M, Zucchetti G, Bazzano D, Ricci F, Vassallo E, et al. Rehabilitative intervention during and after pediatric hematopoietic stem cell transplantation: An analysis of the existing literature. Pediatr Blood Cancer 2016;63(11):1895-904. google scholar
  • Gilliam MB, Madan-Swain A, Whelan K, Tucker DC, Demark-Wahnefried W, Schwebel DC. Cognitive influences as mediators of family and peer support for pediatric cancer survivors’ physical activity. Psychooncology 2013;22(6):1361-8. google scholar
  • McCann L, McMillan KA, Pugh G. Digital interventions to support adolescents and young adults with cancer: systematic review. JMIR Cancer 2019;5(2):e12071. google scholar
  • Tanriverdi M, Cakir E,Akkoyunlu ME, Cakir FB. Effect of virtual reality-based exercise intervention on sleep quality in children with acute lymphoblastic leukemia and healthy siblings: A randomized controlled trial. Palliat Support Care 2022;20(4):455-61. google scholar
  • Spreafico F, Murelli M, Timmons BW, Massimino M, Barr R. Sport activities and exercise as part of routine cancer care in children and adolescents. Pediatr Blood Cancer 2019;66(8):e27826. google scholar
  • Wurz A, Brunet J. Exploring the feasibility and acceptability of a mixedmethods pilot randomized controlled trial testing a 12-week physical activity intervention with adolescent and young adult cancer survivors. Pilot Feasibility Stud 2019;5:154. google scholar
  • Tanriverdi M, Çakir FB. Cancer-Related Fatigue and Daily Living Activities in Pediatric Cancer Survivors. J Pediatr Hematol Oncol 2023;45(5):e567-e572. google scholar

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APA

Çakır, F.B. (2025). PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER. Journal of Advanced Research in Health Sciences, 8(1), 59-62. https://doi.org/10.26650/JARHS2025-1552555


AMA

Çakır F B. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER. Journal of Advanced Research in Health Sciences. 2025;8(1):59-62. https://doi.org/10.26650/JARHS2025-1552555


ABNT

Çakır, F.B. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 8, n. 1, p. 59-62, 2025.


Chicago: Author-Date Style

Çakır, Fatma Betül,. 2025. “PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER.” Journal of Advanced Research in Health Sciences 8, no. 1: 59-62. https://doi.org/10.26650/JARHS2025-1552555


Chicago: Humanities Style

Çakır, Fatma Betül,. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER.” Journal of Advanced Research in Health Sciences 8, no. 1 (Mar. 2025): 59-62. https://doi.org/10.26650/JARHS2025-1552555


Harvard: Australian Style

Çakır, FB 2025, 'PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER', Journal of Advanced Research in Health Sciences, vol. 8, no. 1, pp. 59-62, viewed 12 Mar. 2025, https://doi.org/10.26650/JARHS2025-1552555


Harvard: Author-Date Style

Çakır, F.B. (2025) ‘PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER’, Journal of Advanced Research in Health Sciences, 8(1), pp. 59-62. https://doi.org/10.26650/JARHS2025-1552555 (12 Mar. 2025).


MLA

Çakır, Fatma Betül,. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER.” Journal of Advanced Research in Health Sciences, vol. 8, no. 1, 2025, pp. 59-62. [Database Container], https://doi.org/10.26650/JARHS2025-1552555


Vancouver

Çakır FB. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER. Journal of Advanced Research in Health Sciences [Internet]. 12 Mar. 2025 [cited 12 Mar. 2025];8(1):59-62. Available from: https://doi.org/10.26650/JARHS2025-1552555 doi: 10.26650/JARHS2025-1552555


ISNAD

Çakır, FatmaBetül. PHYSICAL THERAPY INTERVENTIONS IN CHILDREN WITH CANCER”. Journal of Advanced Research in Health Sciences 8/1 (Mar. 2025): 59-62. https://doi.org/10.26650/JARHS2025-1552555



TIMELINE


Submitted18.09.2024
Accepted11.11.2024
Published Online22.01.2025

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