Journal of Child

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DOI :10.26650/jchild.2025.1592466   IUP :10.26650/jchild.2025.1592466    Full Text (PDF)

Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results

Serra Karaca, Kemal Nişli

Objective: Atrial Septal Defect (ASD), one of the most common congenital heart diseases, is usually asymptomatic in childhood, but is associated with long-term consequences such as arrhythmia, stroke, heart failure and pulmonary hypertension. In our study, we aimed to present our experiences in our center and provide information about the arrhythmias we encountered after transcatheter ASD closure, possible risk factors and their course.

Methods:  In our study, the files of patients who underwent transcatheter ASD closure in our clinic between 2010 and 2020 were retrospectively scanned. It is a cross-sectional descriptive study. A total of 216 patients were included in our study (131 girls 60.6%, 85 boys 39.4%).. Since our study aimed to detect arrhythmias that developed after ASD closure, even though the follow-up period was long the data especially in the f irst 6 months after the procedure were evaluated. These evaluated data are: ECG findings, complaints expressed by the patients, if any, and 24-hour rhythm Holter results deemed necessary accordingly.

Results: 216 patients (131 girls 60.6%, 85 boys 39.4%) whose data could be accessed in their files were included in our study. The mean age of the patients was 79±48.5 months (min 30 months, max:17 years ). The average ASD size of the patients was 14.27±3.85 mm (min: 9 mm, max:26 mm) and the mean device size was 16.8±3.7 mm (min: 10mm, max: 28 mm). All the patients were at sinus rhythm prior to procedure. Arrhythmia was detected in 13 of the 216 patients included in the study after the closure procedure. The arrhythmia rate after closure was 6%. Of the 13 patients with arrhythmia, supraventricular premature beat (SVE) was detected in 6, ventricular premature beat (VES) in 2, supraventricular tachycardia (SVT) in 2 patients, 1st degree AV block in 1 patient, 2nd degree AV block in 1 patient and 3rd degree AV block in 1 patient.

Conclusions: Arrhythmias that develop after transcatheter treatment are not common and are usually temporary. The best option is to evaluate each patient individually and decide on closure at the most appropriate age possible.

Keywords: ASD, arrhythmia, transcatheter closure

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References

  • Craig, R.J.; Selzer, A. Natural History and Prognosis of Atrial Septal Defect. Circulation 1968, 37, 805–815. google scholar
  • Siddiqui WT, Usman T, Atiq M, Amanullah MM. Transcatheter versus surgical closure of the atrial septum defect: a debate from a developing country. J Cardiovasc Thorac Res. 2014;6(4):205-210. google scholar
  • Ooi YK, Kelleman M, Ehrlich A et al. Transcatheter Versus surgical closure of atrial septal defects in children: a value comparison. JACC Cardiovasc Intv. 2016;9(1):79-86. google scholar
  • Murphy, J.G.; Gersh, B.J.; McGoon, M.D.; Mair, D.D.; Porter, C.J.; Ilstrup, D.M.; McGoon, D.C.; Puga, F.J.; Kirklin, J.W.; Danielson, G.K. Long-Term Outcome after Surgical Repair of Isolated Atrial Septal Defect. N. Engl. J. Med. 1990, 323, 1645–1650. google scholar
  • Silversides C, Haberer K Siu S, Webb G, Benson L, McLaughlin P. Predictors of atrial arrhythmias after device closure of secundumtype atrial septal defects in adults. Am J Cardiol 2008;101:683–7. google scholar
  • Williams MR, Perry JC. Arrhythmias and conduction disorders associated with atrial septal defects. J Thorac Dis. 2018;10(Suppl 24):2940–2944. google scholar
  • Suda K, Raboisson MJ, Piette E et al. Reversible atrioventricular block associated with the closure of atrial septal defects using the Am platzer device. J Am Coll Cardiol. 2004;43(9):1677– 1682. google scholar
  • Chessa M, Carminati M, Butera G et al. Early and late complications associated with transcatheter occlusion of the secundum atrial septal defect. J Am Coll Cardiol. 2002;39(6):1061–1065 google scholar
  • Hill SL, Berul CI, Patel HT, Rhodes J, Supran SE, Cao QL, et al. Early ECG abnormalities associated with transcatheter closure of the atrial septal defect using Amplatzer septal occluder. J Interv Card Electrophysiol 2000; 4: 469–474. google scholar
  • Komar M, Przewłocki T, Olszowska M, Sobień B, Stępniewski J, Podolec J, Mleczko S, Tomkiewicz-Pająk L, Zmudka K, Podolec P. Conduction abnormality and arrhythmia after transcatheter closure of atrial septal defect. Circ J. 2014;78(10):2415-21. Epub 2014 Aug 22. PMID: 25253507. google scholar
  • Szkutnik M, Lenarczyk A, Kusa J, Białkowski J. Symptomatic tachy-and bradyarrhythmias after transcatheter closure of interatrial communications with Amplatzer devices. Cardiol J 2008; 15: 510–516. google scholar
  • Wilson NJ, Smith J, Prommete B, O’Donnell C, Gentles TL, Ruygrok PN. Transcatheter closure of secundum atrial septal defects with the Amplatzer septal occluder in adults and children: Follow-up closure rates, degree of mitral regurgitation and evolution of arrhythmias. Heart Lung Circ 2008; 17: 318–324. google scholar
  • Mazzanti A, Kanthan A, Monteforte N, Memmi M, Bloise R, Novelli V et al. Novel insight into the natural history of short QT syndrome. J Am Coll Cardiol 2014; 63: 1300–1308. google scholar
  • Komar M, Przewlocki T, Olszowska M, Sobien B, Podolec P. The benefit of atrial septal defect closure in elderly patients. Clin Interv Aging 2014; 9: 1101–1107. google scholar
  • Komar M, Przewłocki T, Olszowska M, Sobień B, Tomkiewicz Pająk L, Podolec P. Is it worth closing the atrial septal defect in patients with an insignificant shunt? Postepy Kardiol Interwencyjnej 2014; 10: 78–83. google scholar
  • Cuypers JA, Opic P, Menting ME, Utens EM, Witsenburg M, Helbing WA et al. The unnatural history of an atrial septal defect: longitudinal 35-year follow-up after surgical closure at young age. Heart 2013;99:1346–52. google scholar
  • Brochu MC, Baril JF, Dore A et al. Improvement in exercise capacity in asymptomatic and mildly symptomatic adults after atrial septal defect percutaneous closure. Circulation 2002; 106: 1821-6. google scholar
  • Roos-Hesselink JW, Meijboom FJ, Spitaels SE, et al. Excellent survival and low incidence of arrhythmias, stroke, and heart failure long-term after surgical ASD closure at a young age. A prospective follow-up study of 21–33 years. Eur Heart J 2003; 24: 190-7. google scholar
  • Konstantinides S, Geibel A, Olschewski M et al. A comparison of surgical and medical therapy for atrial septal defect in adults. N Engl J Med 1995; 333: 469-73 google scholar
  • Horvath KA, Burke RP, Collins JJ, Cohn LH. Surgical treatment of adult atrial septal defect: early and long-term results. J Am Coll Cardiol 1992; 20: 1156-9. google scholar
  • Yüce M, Ozer O, Cakici M et al. Closure of the secundum atrial septal defects by the Amplatzer occluder device. Turk Kardiyol Dern Ars 2011; 39: 35-40 google scholar
  • X. Li, E. Wissner, M. Kamioka, H. Makimoto, P. Rausch, A. Metzner, et al., Safety and feasibility of transseptal puncture for atrial fibrillation ablation in patients with atrial septal defect closure devices, Heart Rhythm. 11 (2014) 330–335. google scholar

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APA

Karaca, S., & Nişli, K. (2025). Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results. Journal of Child, 25(1), 39-43. https://doi.org/10.26650/jchild.2025.1592466


AMA

Karaca S, Nişli K. Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results. Journal of Child. 2025;25(1):39-43. https://doi.org/10.26650/jchild.2025.1592466


ABNT

Karaca, S.; Nişli, K. Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results. Journal of Child, [Publisher Location], v. 25, n. 1, p. 39-43, 2025.


Chicago: Author-Date Style

Karaca, Serra, and Kemal Nişli. 2025. “Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results.” Journal of Child 25, no. 1: 39-43. https://doi.org/10.26650/jchild.2025.1592466


Chicago: Humanities Style

Karaca, Serra, and Kemal Nişli. “Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results.” Journal of Child 25, no. 1 (Aug. 2025): 39-43. https://doi.org/10.26650/jchild.2025.1592466


Harvard: Australian Style

Karaca, S & Nişli, K 2025, 'Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results', Journal of Child, vol. 25, no. 1, pp. 39-43, viewed 12 Aug. 2025, https://doi.org/10.26650/jchild.2025.1592466


Harvard: Author-Date Style

Karaca, S. and Nişli, K. (2025) ‘Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results’, Journal of Child, 25(1), pp. 39-43. https://doi.org/10.26650/jchild.2025.1592466 (12 Aug. 2025).


MLA

Karaca, Serra, and Kemal Nişli. “Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results.” Journal of Child, vol. 25, no. 1, 2025, pp. 39-43. [Database Container], https://doi.org/10.26650/jchild.2025.1592466


Vancouver

Karaca S, Nişli K. Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results. Journal of Child [Internet]. 12 Aug. 2025 [cited 12 Aug. 2025];25(1):39-43. Available from: https://doi.org/10.26650/jchild.2025.1592466 doi: 10.26650/jchild.2025.1592466


ISNAD

Karaca, Serra - Nişli, Kemal. “Arrhythmias developing after Transcatheter Atrial Septal Defect closure: Single-center follow-up results”. Journal of Child 25/1 (Aug. 2025): 39-43. https://doi.org/10.26650/jchild.2025.1592466



TIMELINE


Submitted27.11.2024
Accepted05.12.2024
Published Online30.06.2025

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