Journal of Child

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DOI :10.5222/j.child.2014.072   IUP :10.5222/j.child.2014.072    Full Text (PDF)

The Effect of Obesity on Asthma in Children

Mahmut Doğru, İlknur Bostancı, Serap Özmen, Handan Duman Şenol, Gülay Başarır

Introduction: The prevalence of obesity and asthma is increasing in recent years. Obesity is a risk factor for asthma. The presence of obesity may affect the clinical course of the disease in patients with asthma. This study was conducted to determine the effect of obesity on clinical course of asthma and pulmonary function tests in children with asthma. Material and Method: One hundred and sixty children with asthma who were followed in Pediatric ImmunologyAllergy Clinic were included in this study. Patients were evaluated prospectively between January 2011-June 2011. The patients were interrogated with detailed history of allergic disease, age, kin marriage, familial atopy, exposure to tobacco smoke, number of asthma attacks within the previous year, and systemic steroid use. Asthma control test, pulmonary function tests, skin prick tests, eosinophilia and total immunoglobulin E measurements were performed. Patients with waist circumferences above the 90th percentile were considered obese. Results: Ninety-six (60%) patients were of normal weight and 64 (40%) of them were obese. There were no statistically significant difference between both groups in terms of age, gender, consanguinity, family history of atopy, smoking, and atopy. The number of attacks and need of systemic steroid within the previous one year were significantly higher in obese asthmatics compared to normalweight individuals (p<0.05). Asthma control in obese asthmatics was significantly worse (p<0.05). There were no statistically significant intergroup difference in terms of serum total IgE, eosinophilia and respiratory function parameters (p>0.05). Binary logistic regression analysis was used to investigate the variables that were effective on asthma control (age, family history of asthma, BMI, WC, number of attacks, systemic steroid use, FEV1, FVC, FEV1/FVC, PEF, and MEF 25-75). The effect of BMI was found to be greater (OR: 39 Cl: (0.36, 4435)). Discussion and Conclusion: Obesity worsens asthma control, increases systemic steroid use and the number of attacks in our patients with asthma. Weight loss together with appropriate treatment and avoidance from allergens may improve asthma control in these patients. 

Keywords: Obesity, asthma, child
DOI :10.5222/j.child.2014.072   IUP :10.5222/j.child.2014.072    Full Text (PDF)

Çocuklarda Obezitenin Astıma Etkisi

Mahmut Doğru, İlknur Bostancı, Serap Özmen, Handan Duman Şenol, Gülay Başarır

Amaç: Astım ve obezite sıklığı son yıllarda artmaktadır. Obezite astım açısından bir risk faktörüdür. Astımlı hastalarda obezite varlığı hastalığı klinik seyrini etkileyebilmektedir. Astım tanısı olan hastalarda obezitenin astımın klinik seyri ve solunum fonksiyon testleri üzerine etkisini saptamak amacıyla bu çalışma yapılmıştır. Gereç ve Yöntem: Çalışmaya Çocuk İmmünolojisi ve Allerji Polikliniğinde astım tanısı ile takip edilen 160 çocuk (18 yaş altı) hasta alındı. Hastalar Ocak 2011 - Haziran 2011 arasında prospektif olarak değerlendirildi. Hastaların ayrıntılı allerjik hastalık öyküsü, yaş, akraba evliliği, ailede atopi öyküsü, sigara dumanına maruziyet, son 1 yıldaki atak sayısı ve sistemik steroid alma sıklığı sorgulandı. Astım kontrol testi solunum fonksiyon testleri, deri prick testleri, eozinofili ve total immunglobulin E ölçümü yapıldı. Bel çevresi 90.p’in üstündeki hastalar obez olarak kabul edildi. Bulgular: Hastaların 96’sı (%60) normal kilolu, 64’ü (%40) obez idi. İki grup arasında yaş, cinsiyet, akraba evliliği, ailede atopi öyküsü, sigara, atopi açısından anlamlı farklılık bulunmadı. Obez olan astımlıların son 1 yıldaki atak sayıları ve sistemik steroid gereksinimleri, normal kilolulara göre anlamlı olarak fazlaydı (p<0.05). Obez olan astımlılarda astım kontrolü anlamlı olarak daha kötüydü (p<0.05). Gruplar arasında serum total IgE, eozinofili varlığı ve solunum fonksiyon parametreleri açısından istatistiksel olarak anlamlı değildi (p>0.05). Astım kontrolü üzerinde etkili olan değişkenlerin araştırıldığı binary logistic regresyon analizinde (yaş, ailede astım, VKİ, BÇ, atak sayısı, sistemik steroid kullanımı, FEV1, FVC, FEV1/ FVC, PEF, MEF 25-75’e göre yapılan) VKİ’nin etkisinin daha büyük olduğu saptandı (OR: 39 CI: (0.36, 4435)). Tartışma ve Sonuç: Astımlı hastalarımızda obezite astım kontrolünü kötüleştirmekte, atak sayısı ve sistemik steroid kullanımını arttırmaktadır. Uygun tedavi, alerjenden korunma önlemleri yanında kilo kaybedilmesi ile hastaların astım kontrolünde iyileşme sağlanabilir.

Keywords: Obezite, astım, çocuk

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APA

Doğru, M., Bostancı, İ., Özmen, S., Duman Şenol, H., & Başarır, G. (2014). The Effect of Obesity on Asthma in Children. Journal of Child, 14(2), 72-77. https://doi.org/10.5222/j.child.2014.072


AMA

Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G. The Effect of Obesity on Asthma in Children. Journal of Child. 2014;14(2):72-77. https://doi.org/10.5222/j.child.2014.072


ABNT

Doğru, M.; Bostancı, İ.; Özmen, S.; Duman Şenol, H.; Başarır, G. The Effect of Obesity on Asthma in Children. Journal of Child, [Publisher Location], v. 14, n. 2, p. 72-77, 2014.


Chicago: Author-Date Style

Doğru, Mahmut, and İlknur Bostancı and Serap Özmen and Handan Duman Şenol and Gülay Başarır. 2014. “The Effect of Obesity on Asthma in Children.” Journal of Child 14, no. 2: 72-77. https://doi.org/10.5222/j.child.2014.072


Chicago: Humanities Style

Doğru, Mahmut, and İlknur Bostancı and Serap Özmen and Handan Duman Şenol and Gülay Başarır. “The Effect of Obesity on Asthma in Children.” Journal of Child 14, no. 2 (Apr. 2025): 72-77. https://doi.org/10.5222/j.child.2014.072


Harvard: Australian Style

Doğru, M & Bostancı, İ & Özmen, S & Duman Şenol, H & Başarır, G 2014, 'The Effect of Obesity on Asthma in Children', Journal of Child, vol. 14, no. 2, pp. 72-77, viewed 30 Apr. 2025, https://doi.org/10.5222/j.child.2014.072


Harvard: Author-Date Style

Doğru, M. and Bostancı, İ. and Özmen, S. and Duman Şenol, H. and Başarır, G. (2014) ‘The Effect of Obesity on Asthma in Children’, Journal of Child, 14(2), pp. 72-77. https://doi.org/10.5222/j.child.2014.072 (30 Apr. 2025).


MLA

Doğru, Mahmut, and İlknur Bostancı and Serap Özmen and Handan Duman Şenol and Gülay Başarır. “The Effect of Obesity on Asthma in Children.” Journal of Child, vol. 14, no. 2, 2014, pp. 72-77. [Database Container], https://doi.org/10.5222/j.child.2014.072


Vancouver

Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G. The Effect of Obesity on Asthma in Children. Journal of Child [Internet]. 30 Apr. 2025 [cited 30 Apr. 2025];14(2):72-77. Available from: https://doi.org/10.5222/j.child.2014.072 doi: 10.5222/j.child.2014.072


ISNAD

Doğru, Mahmut - Bostancı, İlknur - Özmen, Serap - Duman Şenol, Handan - Başarır, Gülay. “The Effect of Obesity on Asthma in Children”. Journal of Child 14/2 (Apr. 2025): 72-77. https://doi.org/10.5222/j.child.2014.072



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