Journal of Child

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Case Report


DOI :10.5222/j.child.2019.93275   IUP :10.5222/j.child.2019.93275    Full Text (PDF)

A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma

Özge Bayrak Demirel, Serap Karaman, Ayşe Özkan Karagenç, Deniz Tuğcu, İbrahim Adaletli, Rejin Kebudi, Ayşegül Ünüvar, Zeynep Karakaş

A 17-year-old girl in whom the diagnosis of epithelioid hemangioendothelioma was established in four different segments of the liver incidentally was referred to us. Further examination of tru-cut biopsy material showed multiple metastatic lesions in the brain and both lungs. Since the patient was asymptomatic, she was followed up without treatment for a year. At the first-year control visit, the radiologic examination indicated a stable epithelioid hemangioendothelioma without any new metastatic lesion, and increase in the dimensions of the mass lesion. The management of epithelioid hemangioendothelioma consists of surgical treatment, drug administration such as bevacizumab or follow-up without treatment. The course of the disease in our patient encouraged follow-up of asymptomatic patients with epithelioid hemangioendothelioma without treatment, regardless of the extent of metastatic lesions,and dimensions of the mass lesion 

Keywords: Metastasis, multifocal epithelioid hemangioendothelioma, vascular tumor
DOI :10.5222/j.child.2019.93275   IUP :10.5222/j.child.2019.93275    Full Text (PDF)

Çocukluk Çağının Ender Bir Neoplastik Hastalığı: Multifokal Epiteloid Hemanjioendotelyoma Vakası

Özge Bayrak Demirel, Serap Karaman, Ayşe Özkan Karagenç, Deniz Tuğcu, İbrahim Adaletli, Rejin Kebudi, Ayşegül Ünüvar, Zeynep Karakaş

On yedi yaşında kız hasta, karaciğerde dört farklı segmentte insidental olarak saptanmış epiteloid hemanjioendotelyoma tanısıyla tarafımıza yönlendirildi. Karaciğer tru-cut biyopsi materyalinin yeniden incelenmesi sonucunda epiteloid hemanjioendotelyoma ile uyumlu olduğu görüldü. Yapılan tetkiklerinde akciğer ve beyinde multipl metastatik odaklar saptanan hasta asemptomatik olduğundan tedavisiz izlemine karar verildi. Bir yıllık izlem süresi boyunca herhangi bir semptomu olmayan hastamızın bir yıl sonundaki kontrol görüntülemelerinde kitlelerin boyutlarının artmadığı ve yeni bir metastaz olmadığı görüldü. Multipl metastazı olan epiteloid hemanjioendotelyoma vakaları için bevacizumab terapisi veya cerrahi tedavi yöntemleri uygulanabilmektedir. Hastamızın seyri, kitle boyutlarına ve metastaz yaygınlığına bakılmaksızın, asemptomatik epiteloid hemanjioendotelyoma hastalarının tedavisiz izlemi için cesaret verici olmuştur.

Keywords: Metastaz, multifokal epiteloid hemanjioendotelyoma, vasküler tümör

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Citations

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APA

Bayrak Demirel, Ö., Karaman, S., Özkan Karagenç, A., Tuğcu, D., Adaletli, İ., Kebudi, R., Ünüvar, A., & Karakaş, Z. (2019). A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma. Journal of Child, 19(1), 48-50. https://doi.org/10.5222/j.child.2019.93275


AMA

Bayrak Demirel Ö, Karaman S, Özkan Karagenç A, Tuğcu D, Adaletli İ, Kebudi R, Ünüvar A, Karakaş Z. A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma. Journal of Child. 2019;19(1):48-50. https://doi.org/10.5222/j.child.2019.93275


ABNT

Bayrak Demirel, Ö.; Karaman, S.; Özkan Karagenç, A.; Tuğcu, D.; Adaletli, İ.; Kebudi, R.; Ünüvar, A.; Karakaş, Z. A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma. Journal of Child, [Publisher Location], v. 19, n. 1, p. 48-50, 2019.


Chicago: Author-Date Style

Bayrak Demirel, Özge, and Serap Karaman and Ayşe Özkan Karagenç and Deniz Tuğcu and İbrahim Adaletli and Rejin Kebudi and Ayşegül Ünüvar and Zeynep Karakaş. 2019. “A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma.” Journal of Child 19, no. 1: 48-50. https://doi.org/10.5222/j.child.2019.93275


Chicago: Humanities Style

Bayrak Demirel, Özge, and Serap Karaman and Ayşe Özkan Karagenç and Deniz Tuğcu and İbrahim Adaletli and Rejin Kebudi and Ayşegül Ünüvar and Zeynep Karakaş. “A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma.” Journal of Child 19, no. 1 (May. 2024): 48-50. https://doi.org/10.5222/j.child.2019.93275


Harvard: Australian Style

Bayrak Demirel, Ö & Karaman, S & Özkan Karagenç, A & Tuğcu, D & Adaletli, İ & Kebudi, R & Ünüvar, A & Karakaş, Z 2019, 'A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma', Journal of Child, vol. 19, no. 1, pp. 48-50, viewed 18 May. 2024, https://doi.org/10.5222/j.child.2019.93275


Harvard: Author-Date Style

Bayrak Demirel, Ö. and Karaman, S. and Özkan Karagenç, A. and Tuğcu, D. and Adaletli, İ. and Kebudi, R. and Ünüvar, A. and Karakaş, Z. (2019) ‘A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma’, Journal of Child, 19(1), pp. 48-50. https://doi.org/10.5222/j.child.2019.93275 (18 May. 2024).


MLA

Bayrak Demirel, Özge, and Serap Karaman and Ayşe Özkan Karagenç and Deniz Tuğcu and İbrahim Adaletli and Rejin Kebudi and Ayşegül Ünüvar and Zeynep Karakaş. “A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma.” Journal of Child, vol. 19, no. 1, 2019, pp. 48-50. [Database Container], https://doi.org/10.5222/j.child.2019.93275


Vancouver

Bayrak Demirel Ö, Karaman S, Özkan Karagenç A, Tuğcu D, Adaletli İ, Kebudi R, Ünüvar A, Karakaş Z. A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma. Journal of Child [Internet]. 18 May. 2024 [cited 18 May. 2024];19(1):48-50. Available from: https://doi.org/10.5222/j.child.2019.93275 doi: 10.5222/j.child.2019.93275


ISNAD

Bayrak Demirel, Özge - Karaman, Serap - Özkan Karagenç, Ayşe - Tuğcu, Deniz - Adaletli, İbrahim - Kebudi, Rejin - Ünüvar, Ayşegül - Karakaş, Zeynep. “A Rare Neoplastic Disease of Childhood: Multifocal Epithelioid Hemangioendothelioma”. Journal of Child 19/1 (May. 2024): 48-50. https://doi.org/10.5222/j.child.2019.93275



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Published Online30.04.2019

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