Journal of Child

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Case Report


DOI :10.5222/j.child.2018.58224   IUP :10.5222/j.child.2018.58224    Full Text (PDF)

Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report

Sevliya Öcal Demir, Gürkan Atay, Özge Kangallı, Manolya Kara, Özge Kaba, Emel Çakar, Mehmet Akif Durmuş, Selda Hançerli Törün, Gülden Gökçay, Nezahat Gürler, Ayper Somer

Linezolid and vancomycin have been used successfully in the treatment of infections caused by multidrug resistant gram-positive bacteria. Due to the similarity of the antibacterial spectrum, they are not classically used in combination. Herein we present a patient who was successfully treated for catheter-related bloodstream infection and ventilator-associated pneumonia with linezolid and vancomycin combination. Our experience was that; linezolid and vancomycin combination can be used when either patient has a resistant Gram-positive bacterial infection or has a new onset severe infection that can not be treated with bacteriostatic agents.

Keywords: Linezolid, vancomycin, pneumonia
DOI :10.5222/j.child.2018.58224   IUP :10.5222/j.child.2018.58224    Full Text (PDF)

Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu

Sevliya Öcal Demir, Gürkan Atay, Özge Kangallı, Manolya Kara, Özge Kaba, Emel Çakar, Mehmet Akif Durmuş, Selda Hançerli Törün, Gülden Gökçay, Nezahat Gürler, Ayper Somer

Linezolid ve vankomisin çok ilaca dirençli Gram pozitif bakterilerin neden olduğu infeksiyonların tedavisinde günümüzde başarıyla kullanılmaktadır. Etki spektrumlarının benzerliği nedeniyle klasik olarak birlikte kullanılmazlar. Bu makalede, ventilatör ilişkili pnömoni ve kateter ilişkili kan akımı infeksiyonu nedeniyle; vankomisin ve linezolid tedavilerinin beraber kullanıldığı ve tedaviye olumlu yanıt alınan bir hastayı sunduk. Edindiğimiz tecrübe, linezolid tedavisi almakta olan hastada dirençli Gram pozitif bakteriler ile bakteriostatik tedavi verilemeyecek kadar ciddi yeni bir infeksiyon geliştiğinde, linezolid ve vankomisin tedavilerini beraber kullanabileceğimiz kanısı oluşturdu.

Keywords: Linezolid, vankomisin, pnömoni

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References

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Citations

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APA

Öcal Demir, S., Atay, G., Kangallı, Ö., Kara, M., Kaba, Ö., Çakar, E., Durmuş, M.A., Hançerli Törün, S., Gökçay, G., Gürler, N., & Somer, A. (2018). Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report. Journal of Child, 18(2), 93-96. https://doi.org/10.5222/j.child.2018.58224


AMA

Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş M A, Hançerli Törün S, Gökçay G, Gürler N, Somer A. Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report. Journal of Child. 2018;18(2):93-96. https://doi.org/10.5222/j.child.2018.58224


ABNT

Öcal Demir, S.; Atay, G.; Kangallı, Ö.; Kara, M.; Kaba, Ö.; Çakar, E.; Durmuş, M.A.; Hançerli Törün, S.; Gökçay, G.; Gürler, N.; Somer, A. Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report. Journal of Child, [Publisher Location], v. 18, n. 2, p. 93-96, 2018.


Chicago: Author-Date Style

Öcal Demir, Sevliya, and Gürkan Atay and Özge Kangallı and Manolya Kara and Özge Kaba and Emel Çakar and Mehmet Akif Durmuş and Selda Hançerli Törün and Gülden Gökçay and Nezahat Gürler and Ayper Somer. 2018. “Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report.” Journal of Child 18, no. 2: 93-96. https://doi.org/10.5222/j.child.2018.58224


Chicago: Humanities Style

Öcal Demir, Sevliya, and Gürkan Atay and Özge Kangallı and Manolya Kara and Özge Kaba and Emel Çakar and Mehmet Akif Durmuş and Selda Hançerli Törün and Gülden Gökçay and Nezahat Gürler and Ayper Somer. “Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report.” Journal of Child 18, no. 2 (Nov. 2024): 93-96. https://doi.org/10.5222/j.child.2018.58224


Harvard: Australian Style

Öcal Demir, S & Atay, G & Kangallı, Ö & Kara, M & Kaba, Ö & Çakar, E & Durmuş, MA & Hançerli Törün, S & Gökçay, G & Gürler, N & Somer, A 2018, 'Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report', Journal of Child, vol. 18, no. 2, pp. 93-96, viewed 5 Nov. 2024, https://doi.org/10.5222/j.child.2018.58224


Harvard: Author-Date Style

Öcal Demir, S. and Atay, G. and Kangallı, Ö. and Kara, M. and Kaba, Ö. and Çakar, E. and Durmuş, M.A. and Hançerli Törün, S. and Gökçay, G. and Gürler, N. and Somer, A. (2018) ‘Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report’, Journal of Child, 18(2), pp. 93-96. https://doi.org/10.5222/j.child.2018.58224 (5 Nov. 2024).


MLA

Öcal Demir, Sevliya, and Gürkan Atay and Özge Kangallı and Manolya Kara and Özge Kaba and Emel Çakar and Mehmet Akif Durmuş and Selda Hançerli Törün and Gülden Gökçay and Nezahat Gürler and Ayper Somer. “Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report.” Journal of Child, vol. 18, no. 2, 2018, pp. 93-96. [Database Container], https://doi.org/10.5222/j.child.2018.58224


Vancouver

Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş MA, Hançerli Törün S, Gökçay G, Gürler N, Somer A. Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report. Journal of Child [Internet]. 5 Nov. 2024 [cited 5 Nov. 2024];18(2):93-96. Available from: https://doi.org/10.5222/j.child.2018.58224 doi: 10.5222/j.child.2018.58224


ISNAD

Öcal Demir, Sevliya - Atay, Gürkan - Kangallı, Özge - Kara, Manolya - Kaba, Özge - Çakar, Emel - Durmuş, MehmetAkif - Hançerli Törün, Selda - Gökçay, Gülden - Gürler, Nezahat - Somer, Ayper. “Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report”. Journal of Child 18/2 (Nov. 2024): 93-96. https://doi.org/10.5222/j.child.2018.58224



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Published Online31.08.2018

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