Review Article


DOI :10.5222/j.child.2010.116   IUP :10.5222/j.child.2010.116    Full Text (PDF)

Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old

Burçin NalbantoğluAyşin NalbantoğluNihan Uygur KülcüAysu Say

Objective: After Ministry of Health included hepatitis B vaccine in routine vaccination programme, we aimed to determine hepatitis B seroprevalance and immunization status of children born after 1998. Methods: Case group consisted of 302 children admitted to our clinic,without any history of jaundice, chronic disease, and blood transfusions. HBsAg and Anti-HBs are studied with microelisa method in serum aliquots. Questionnaires about socioeconomic levels of patients were applied, and vaccination status was determined according to vaccination registry cards. Results: HBsAg positivity was found to be 1 % among 302 patients. Anti-HBsAg positivity was detected as 90.4 % in 9 months-3 year- old group, 89.5 % in 3 -5 year- old group and 73 % in 5-8 year- old group, respectively. In all age groups overall anti-HBsAg positivity was 83.1 %. At least three doses of hepatitis B vaccination were done in 8.47 % of 9 months-3 year- old group, in 89.48 % of 3 -5 year- old group, and in 72.96 % of 5 -8 year- old group, respectively. Conclusion: We found that with increasing age, vaccination rates and anti-HBsAg values are decreased. Howeever when compared with studies performed before hepatitis B vacccine was taken into routine vaccination programme, hepatitis B vaccination status and anti-HBsAg values are significantly increased and HBsAg positivity is significantly decreased. So we think that vaccination programme must be continued and patients must be informed of the importance of vaccination.

DOI :10.5222/j.child.2010.116   IUP :10.5222/j.child.2010.116    Full Text (PDF)

Dokuz Ay - 8 Yaş Arası Çocuklarda Hepatit B Seroprevalansı ve Aşılanma Durumları

Burçin NalbantoğluAyşin NalbantoğluNihan Uygur KülcüAysu Say

Amaç: Sağlık Bakanlığı’nın Hepatit B aşısını rutin aşı takvimine dahil etmesinden sonra, bu tarihten sonra doğan çocuklarda Hepatit B seroprevalansı ve aşılanma durumlarını belirlemeyi amaçladık. Yöntemler: Vaka grubu hastanemiz çocuk kliniğine getirilen, daha önce hiç sarılık geçirmemiş, kronik bir hastalığı bulunmayan, hiç kan transfüzyonu almamış 302 çocuktan oluşturuldu. Ayrılan serumlarda HBsAg, Anti HBsAg testleri mikroElisa sistemi ile çalışıldı. Hastalara sosyoekonomik düzeyleri ile ilgili sorular soruldu ve aşılanma durumları aşı kartlarına göre belirlendi. Bulgular: HBsAg pozitifliği: % 1.0 olarak saptandı. AntiHBsAg pozitifliği: 9 ay-3 yaş arası % 90.4, 3-5 yaş arası % 89.5, 5-8 yaş arası ise % 73.0 olarak saptandı, genel anti-HBsAg pozitifliği ise % 83.1 olarak bulundu. Hepatit B aşılanma durumu: En az 3 doz aşı yapılma oranı 9 ay-3 yaş arası % 88.47, 3-5 yaş arası % 89.48, 5-8 yaş arası ise % 72.96 olarak saptandı. Sonuç: Bulgular değerlendirildiğinde yaşla beraber aşılanma oranlarının azaldığı, anti HBsAg değerlerinin düştüğü saptandı. Ancak, Hepatit B aşısının rutin aşı takvimine girmesinden önce yapılan çalışmalarla karşılaştırıldığında Hepatit B aşılanma durumu ve anti-HBsAg değerlerinin anlamlı derecede arttığı, HBsAg pozitifliğinin ise anlamlı olarak azaldığı saptandı. Bu bakımdan aşı programının aynı şekilde devam etmesi ve hastaların bu konuda bilinçlendirilmesi zorunludur.


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APA

Nalbantoğlu, B., Nalbantoğlu, A., Külcü, N.U., & Say, A. (2010). Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old. Journal of Child, 10(3), 116-121. https://doi.org/10.5222/j.child.2010.116


AMA

Nalbantoğlu B, Nalbantoğlu A, Külcü N U, Say A. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old. Journal of Child. 2010;10(3):116-121. https://doi.org/10.5222/j.child.2010.116


ABNT

Nalbantoğlu, B.; Nalbantoğlu, A.; Külcü, N.U.; Say, A. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old. Journal of Child, [Publisher Location], v. 10, n. 3, p. 116-121, 2010.


Chicago: Author-Date Style

Nalbantoğlu, Burçin, and Ayşin Nalbantoğlu and Nihan Uygur Külcü and Aysu Say. 2010. “Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old.” Journal of Child 10, no. 3: 116-121. https://doi.org/10.5222/j.child.2010.116


Chicago: Humanities Style

Nalbantoğlu, Burçin, and Ayşin Nalbantoğlu and Nihan Uygur Külcü and Aysu Say. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old.” Journal of Child 10, no. 3 (May. 2025): 116-121. https://doi.org/10.5222/j.child.2010.116


Harvard: Australian Style

Nalbantoğlu, B & Nalbantoğlu, A & Külcü, NU & Say, A 2010, 'Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old', Journal of Child, vol. 10, no. 3, pp. 116-121, viewed 7 May. 2025, https://doi.org/10.5222/j.child.2010.116


Harvard: Author-Date Style

Nalbantoğlu, B. and Nalbantoğlu, A. and Külcü, N.U. and Say, A. (2010) ‘Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old’, Journal of Child, 10(3), pp. 116-121. https://doi.org/10.5222/j.child.2010.116 (7 May. 2025).


MLA

Nalbantoğlu, Burçin, and Ayşin Nalbantoğlu and Nihan Uygur Külcü and Aysu Say. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old.” Journal of Child, vol. 10, no. 3, 2010, pp. 116-121. [Database Container], https://doi.org/10.5222/j.child.2010.116


Vancouver

Nalbantoğlu B, Nalbantoğlu A, Külcü NU, Say A. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old. Journal of Child [Internet]. 7 May. 2025 [cited 7 May. 2025];10(3):116-121. Available from: https://doi.org/10.5222/j.child.2010.116 doi: 10.5222/j.child.2010.116


ISNAD

Nalbantoğlu, Burçin - Nalbantoğlu, Ayşin - Külcü, NihanUygur - Say, Aysu. Seroprevalance of Hepatitis B and Immunization Status of Children Aged Between 9 Months - 8 Years Old”. Journal of Child 10/3 (May. 2025): 116-121. https://doi.org/10.5222/j.child.2010.116



TIMELINE


Published Online30.12.2010

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