Research Article


DOI :10.5222/j.child.2011.097   IUP :10.5222/j.child.2011.097    Full Text (PDF)

Down Sendromu ve Trombositopeni

Belma Saygılı KaragölArda Karagöl

Down sendromu, birçok doğumsal anomalilerle birlikte hematolojik bozuklukların eşlik edebildiği genetik bir hastalıktır. Lösemi benzeri geçici proliferatif bozukluk, lösemi insidansında artış, izole trombositopeni ve trombositoz gibi değişik hematolojik bozukluklar Down sendromunda sıklıkla gözlenmektedir. Down sendromunda görülen trombositopeninin etiyolojisi tam olarak bilinmemekte ve bu konu ile ilgili sınırlı sayıda veri bulunmaktadır. Bu makalede Down sendromu kliniğinin trombositopeni ve diğer hematolojik parametreler üzerine etkisinin değerlendirilerek, Down sendromu ve trombositopeni yaklaşımında gerekli bilgilerin vurgulanması amaçlanmıştır. 

DOI :10.5222/j.child.2011.097   IUP :10.5222/j.child.2011.097    Full Text (PDF)

Down Syndrome and Thrombocytopenia

Belma Saygılı KaragölArda Karagöl

Down syndrome is a genetic disorder associated with various congenital anomalies and hematologic abnormalities. Various hematologic disorders such as transient leukemialike proliferative disorders, increased incidence of leukemia, isolated thrombocytopenia and thrombocytosis were observed in Down syndrome. The etiology of thrombocytopenia in Down syndrome is not exactly kwnown and there are limited data about this subject. In this review, we aimed to to evaluate the impact of the clinics of Down syndrome on thrombocytopenia and other hematologic parameters so as to emphasize necessary information related to the approach to Down syndrome and thrombocytopenia


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APA

Saygılı Karagöl, B., & Karagöl, A. (2011). Down Sendromu ve Trombositopeni. Journal of Child, 11(3), 97-101. https://doi.org/10.5222/j.child.2011.097


AMA

Saygılı Karagöl B, Karagöl A. Down Sendromu ve Trombositopeni. Journal of Child. 2011;11(3):97-101. https://doi.org/10.5222/j.child.2011.097


ABNT

Saygılı Karagöl, B.; Karagöl, A. Down Sendromu ve Trombositopeni. Journal of Child, [Publisher Location], v. 11, n. 3, p. 97-101, 2011.


Chicago: Author-Date Style

Saygılı Karagöl, Belma, and Arda Karagöl. 2011. “Down Sendromu ve Trombositopeni.” Journal of Child 11, no. 3: 97-101. https://doi.org/10.5222/j.child.2011.097


Chicago: Humanities Style

Saygılı Karagöl, Belma, and Arda Karagöl. Down Sendromu ve Trombositopeni.” Journal of Child 11, no. 3 (Aug. 2025): 97-101. https://doi.org/10.5222/j.child.2011.097


Harvard: Australian Style

Saygılı Karagöl, B & Karagöl, A 2011, 'Down Sendromu ve Trombositopeni', Journal of Child, vol. 11, no. 3, pp. 97-101, viewed 17 Aug. 2025, https://doi.org/10.5222/j.child.2011.097


Harvard: Author-Date Style

Saygılı Karagöl, B. and Karagöl, A. (2011) ‘Down Sendromu ve Trombositopeni’, Journal of Child, 11(3), pp. 97-101. https://doi.org/10.5222/j.child.2011.097 (17 Aug. 2025).


MLA

Saygılı Karagöl, Belma, and Arda Karagöl. Down Sendromu ve Trombositopeni.” Journal of Child, vol. 11, no. 3, 2011, pp. 97-101. [Database Container], https://doi.org/10.5222/j.child.2011.097


Vancouver

Saygılı Karagöl B, Karagöl A. Down Sendromu ve Trombositopeni. Journal of Child [Internet]. 17 Aug. 2025 [cited 17 Aug. 2025];11(3):97-101. Available from: https://doi.org/10.5222/j.child.2011.097 doi: 10.5222/j.child.2011.097


ISNAD

Saygılı Karagöl, Belma - Karagöl, Arda. Down Sendromu ve Trombositopeni”. Journal of Child 11/3 (Aug. 2025): 97-101. https://doi.org/10.5222/j.child.2011.097



TIMELINE


Published Online30.12.2011

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