Eski Soruna Yeni Bir Bakış: İnfantil Kolik

Karabayır Nalan; Gökçay Emine

doi:https://dx.doi.org/10.5222/j.child.2017.053

Review

DOI :10.5222/j.child.2017.053 IUP :10.5222/j.child.2017.053 Full Text (PDF)

Eski Soruna Yeni Bir Bakış: İnfantil Kolik

İnfantil kolik, iyi gelişen sağlıklı bebeklerde, daha çok akşam saatlerinde görülen, ataklar hâlinde ortaya çıkan, etiyolojisi tam olarak aydınlatılamamış aşırı ağlama durumudur. İlk kez 1954 yılında Wessel tarafından tanımlanan infantil kolik Rome IV kriterlerine göre yaşamın ilk 5 ayında büyüme geriliği olmayan bebeklerde, görünen bir neden olmadan başlayan ve biten, huzursuzluk/ağlama ile birlikte görülen, bir haftadan daha uzun süren, haftada en az 3 gün günde an az 3 saat devam eden irritabilite nöbetleridir. Kolik prevalansı % 10-40 olarak bildirilmektedir. İnfantil koliğin etiyolojisi tam olarak aydınlatılamamış olup, multifaktöryel olduğu düşünülmektedir. İnfantil kolik ile cinsiyet, doğum tartısı, doğum şekli, beslenme biçimi ilişki saptanmamıştır. Olası risk faktörleri maternal sigara kullanımı, ileri anne yaşı ve ilk bebektir. Son yıllarda intestinal floradaki dengesizliğin koliğe neden olabilecegi konusundaki çalışmalar giderek artmaktadır. Koliğin kesin nedeni bilinemediği için standart bir protokolün oluşturulamaması nedeniyle birçok seçenek uygulanmış, ancak hâlen etkili bir tedavi biçimi bulunamamıştır. İnfantil kolik tedavisinde davranışssal uygulamalarının diğer yöntemlerden daha etkin olduğu bildirilmektedir. Diurnal ritmin olgunlaştığı dönemde spontan olarak kaybolan infantil kolikli bebeklerde migren, atopi, hiperreaktivite gibi sorunların daha sık olduğu bilinmektedir.

Keywords: Ağlama, infantil kolik, inflamasyon, intestinal disbiyozis, sütçocuğu

DOI :10.5222/j.child.2017.053 IUP :10.5222/j.child.2017.053 Full Text (PDF)

New Perspective to the Old Problem: Infantile Colic

Nalan Karabayır, Emine Gülbin Gökçay

Infantile colic is a condition of excessive crying mostly observed in the evening hours in healthy infants, emerging in the form of attacks and of which etiology has not been explored completely. Infantile colic, which was defined by Wessel in 1954 for the first time, as irritability attacks in infants who have no growth retardation within the first 5 months of their lives according to the Rome IV criteria, that start and end without a visible cause which are observed with fuss/crying, last for more than one week, continue for at least 3 days a week and at least 3 hours a day. Prevalence of colic is reported to be 10-40%. The etiology of infantile colic has not been understood completely, but it is thought to be multifactorial. No correlation was determined between infantile colic and gender, birth weight, birth type and diet. The potential risk factors are maternal cigarette use, advanced maternal age and the first baby. In recent years, studies on the subject related to imbalance in the intestinal flora which may cause colic are gradually increasing. Many options have been applied, but an effective treatment type has not been found yet since the absolute reason for colic is not known and thus, a standard protocol cannot be created. It is reported that behavioural practices are more effective in infantile colic treatment than other methods. It is known that the problems such as migraine, atopy and hyperactivity occur more frequently in infants with infantile colic, which spontaneously terminates in the period when the diurnal rhythm develops.

Keywords: Crying, infant, infantile colic, intestinal dysbiosis, inflamation

References

1. Wessel MA, Cobb JC, Jackson EB, Harris GS Jr, Detwiller AC. Paroxysmal fussing in infancy, sometimes called colic. Pediatrics 1954;14:421-35. google scholar
2. Hyman PE, Milla PJ, Benninga MA, Davidson GP, Fleisher DF, Taminiau J. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology 2006;130:1519-26. https://doi.org/10.1053/j.gastro.2005.11.065 google scholar
3. Benninga MA, Faure C, Hyman PE, St James Roberts I, Schechter NL, Nurko S. Childhood functional gastrointestinal disorders: Neonate/Toddler. Gastroenterology 2016 Feb 15 (Aralık 2016). google scholar
4. St James-Roberts I. Persistent crying in infancy. Arch Dis Child 1991;66:653-5. https://doi.org/10.1136/adc.66.5.653 google scholar
5. Barr RG. The early crying paradox: a modest proposal. Hum Nat 1990;1:355-89. https://doi.org/10.1007/BF02734051 google scholar
6. Wolke D, Samara M, Alvarez Wolke. Meta-analysis of fuss/cry durations and colic prevalence across countries: Proceedings of the 11th International Infant Cry Research Workshop, June, 2011; The Netherlands. google scholar
7. Hunziker UA, Barr RG. Increased carrying reduces infant crying: a randomized controlled trial. Pediatrics 1986;77:641-8. google scholar
8. Miller-Loncar C, Bigsby R, High P, Wallach M, Lester B. Infant colic and feding difficulties. Arch Dis Child 2004;89:908-12. https://doi.org/10.1136/adc.2003.033233 google scholar
9. Talachian E, Bidari A, Rezaie MH. Incidence and risk factors for infantile colic in Iranian infants. World J Gastroenterol 2008; 14: 4662-4666. https://doi.org/10.3748/wjg.14.4662 google scholar
10. Turner LT, Palamountain S. Infantile colic: Clinical features and diagnosis. www.uptodate.com. Ağustos 2016 google scholar
11. Lucassen P. Colic. in infants. BMJ Clinical Evidence 2015:08;309. google scholar
12. Tormo R, Bertaccini A, Conde M, Infante D, Cura I. Methane and hydrogen exhalation in normal children and in lactose malabsorbstion. Early Hum Dev 2001;65:165-72. https://doi.org/10.1016/S0378-3782(01)00219-5 google scholar
13. De Weerth C, Fuentes S, de Vos WM. Crying in infants: On the possible role of intestinal microbiota in the development of colic. Gut Microbes 2013;4:416- 21. https://doi.org/10.4161/gmic.26041 google scholar
14. Savino F, Ceratto S, De Marco A, di Montezemolo LC. Looking for new treatments of infantile colic. Ital J Pediatr 2014;5:40-53. https://doi.org/10.1186/1824-7288-40-53 google scholar
15. Savino F, Cordisco L, Tarasco V, Calabrese R, Palumeri E, Matteuzzi D. Molecular identification of coliform bacteria from colicky breastfed infant. Acta Paediatr 2009;98:1582-8. https://doi.org/10.1111/j.1651-2227.2009.01419.x google scholar
16. Biagi E, Nylund L, Candela M, Ostan R, Bucci L, Pini E, et al. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One 2010;5:e10667. https://doi.org/10.1371/journal.pone.0010667 google scholar
17. Rhoads JM, Fatheree NY, Norori J, Liu Y, Lucke JF, Tyson JE, et al. Altered fecal microflora and increased fecal calprotectin in infants with colic. J Pediatr 2009;155:823-8. https://doi.org/10.1016/j.jpeds.2009.05.012 google scholar
18. Ali AM. Helicobacter pylori and infantile colic. Arch Pediatr Adolesc Med 2012;166:648-50. https://doi.org/10.1001/archpediatrics.2011.1241 google scholar
19. Partty A. Kalliomaki M, Salminen S, Isolauri E. Infantile colic is associated low grade systemic inflammation. J Pediatr Gastroenterol Nutr 2016 July (Aralık 2016). google scholar
20. Savino F, Grassino EC, Guidi C, Oggero R, Silvestro L, Miniero R. Ghrelin and motilin concentratin in colicy infants. Acta Paed 2006;95:738-41. https://doi.org/10.1080/08035250500522654 google scholar
21. Lothe L, Ivarsson SA, Lindbeerg T. Motilin and infantile colic. A prospective study. Acta Paediatr Scand 1990;79:410-3, https://doi.org/10.1111/j.1651-2227.1990.tb11485.x google scholar
22. Butler D. Infantile colic and aspirin. Med J Aust 1987;146:179. google scholar
23. Jordan B, Heine RG, Meehan M, Catto -Semith AG, Lubitz L. Effect of antireflux medication, placebo and infant mental health intervention on persistent crying: a randomised clinical trial. J Paediatr Child Health 2006;42:49-58. https://doi.org/10.1111/j.1440-1754.2006.00786.x google scholar
24. Miller AR, Barr RG. Infantile colic. Is it a gut issue? Pediatr North Am 1992;38:1407-23. https://doi.org/10.1016/S0031-3955(16)38227-X google scholar
25. Kanabar D, Randhawa M, Clayton P. Improvement of symptoms in infant colic following reduction of lactose load with lactase. J Hum Nutr Diet 2001;14:359-63. google scholar
26. Camilleri M, Park SY, Scarpato E, Staiano A. Exploring hypotheses and rationale for causes of infantile colic. Neurogastroenterol Motil 2016;1-11. google scholar
27. Rautava P, Helenius H, Lehtonen L. Psychosocial predisposing factors for infantile colic. BMJ 1993;307: 600-4. https://doi.org/10.1136/bmj.307.6904.600 N. Karabayır ve G. Gökçay, Eski Soruna Yeni Bir Bakış: İnfantil Kolik 59 google scholar
28. Kaymaz N, Yıldırım Ş, Topaloğlu N, Gencer M, Binentoğlu FK, Tekin M, et al. Nurs child young people 2015;27:32-8. https://doi.org/10.7748/ncyp.27.10.32.s28 google scholar
29. Halpern R, Coleho R. Excessive crying in infants. J Pediatr (Rio J) 2016;923Suppl 1:S40-S45. https://doi.org/10.1016/j.jped.2016.01.004 google scholar
30. Kurtoglu S, Uzum K, Hallac IK, Coskun A. 5- Hydroxy-3-indole actic acid levels in infantile colic. Is serotinergic tonus responsible for this problem? Acta Paediatr 1997;86:764. https://doi.org/10.1111/j.1651-2227.1997.tb08583.x google scholar
31. Feedman SB, Al-Harty N, Hull- Freedman J. The crying infant: diagnostic testing and frequency of serious underlying disease. Pediatrics 2009;123:841-8. https://doi.org/10.1542/peds.2008-0113 google scholar
32. Garrison MM, Christakis DA. A systematic review of treatments for infant colic. Pediatrics 2000;106:184-90. google scholar
33. Karabıyık N, Oğuz F. İnfantil kolik. Çocuk Dergisi 2009;9:16-21. google scholar
34. Danielsson B, Hwang CP. Treatment of infantile colic with surface active substance (Simethicone). Acta Paediatr Scand 1985;74:446-50. https://doi.org/10.1111/j.1651-2227.1985.tb11001.x google scholar
35. Savino F, Brondello C, Cresi F, Oggero R, Silvestro L. Cimetropium bromide in the treatment of crisis in infantile colic. J Pediatr Gastroenterol Nutr 2002;34: 417-9. https://doi.org/10.1097/00005176-200204000-00020 google scholar
36. Lucassen PL, Assendelft WJ, van Eijk JT, Gubbels JW, Douwes AC, van Geldrop WJ. Systematic review of the occurence of infantil colic in the community. Arch Dis Child 2001;84:398-403. https://doi.org/10.1136/adc.84.5.398 google scholar
37. Thomas DW, McGilligan K, Eisenberg LD, Lieberman HM, Rissman EM. Infantile colic and type of milk feeding. Am J Dis Child 1987;141:451-3. https://doi.org/10.1001/archpedi.1987.04460040109028 google scholar
38. Engler CA, Hadash A, Shehadeh N, Pillar G. Breastfeeding may improve nocturnal sleep and reduce infantile colic: potential role of breast milk melatonin. Eur J Pediatr 2012;171:729-32. https://doi.org/10.1007/s00431-011-1659-3 google scholar
39. Hogdall CK, Vestermark V, Birch M, Plenov G, Toftager-Larsen K. The significance of pregnancy, delivery and postpartum factors for the development of infantile colic. J Perinat Med 1991;19:251-7. google scholar
40. Akhnikh S, Engelberts AC, van Sleuwen BE, L’Hoir MP, Benninga MA. The excessively crying infant: etiology and treatment. Pediatr Ann 2014;43:e69-75. https://doi.org/10.3928/00904481-20140325-07 google scholar
41. Bocquet A, Bresson JL, Briend A, Chouraqui JP, Darmaun D,Dupont C, et al. Infant formulas and soy protein - based formulas: current data. Arch Pediatr 2001;8:1226-33. https://doi.org/10.1016/S0929-693X(01)00615-7 google scholar
42. Vandenplas Y, Alarcon P. Updated algorithms for managing frequent gastro-intestinal symptoms in infants. Beneficial Microbes 2015;6:199-208. https://doi.org/10.3920/BM2014.0075 google scholar
43. Kearney PJ, Malone AJ, Hayes T, Cole M, Hyland M. A trial of lactase in the management of infant colic. J Hum Nutrition Dietetics 1998;11:281-5. https://doi.org/10.1046/j.1365-277X.1998.00108.x google scholar
44. Hall B, Chesters J, Robinson A. Infantile colic:A systematic review of medical and conventional therapies. J Pead Child Health 2012;48:128-37. https://doi.org/10.1111/j.1440-1754.2011.02061.x google scholar
45. Treem WR. Infant colic, a pediatric gastroenterologist’s perspective. Pediatr Clin North Am 1994;41:1121- 1139. https://doi.org/10.1016/S0031-3955(16)38848-4 google scholar
46. Chau K, Lau E, Greenberg S, Jaconson S, YazdaniBrojeni P, Verma N, et al. Probiotics for infantile colic: a randomized, double –blind, placebo-controlled rial investigating Lactobasillus reuteri DSM 17938. J Pediatr 2015;166:74-8. https://doi.org/10.1016/j.jpeds.2014.09.020 google scholar
47. Szajewska H, Dryl R. Probiotics for the management of infantile colic. J Pediatr Gastroenterol Nutr 2016;63 Suppl 1:S22-24. https://doi.org/10.1097/01.mpg.0000489617.90064.4d google scholar
48. Savino F, Fornasero S, Ceratto S, De Marco A, Mandras N, Roana J, et al. Probiotics and gut health in infants: A preliminary case-control observational study about early treatment with Lactobacillus reuteri DSM 17938. Clin Chim Acta 2015; 7;451(Pt A):82-7. google scholar
49. Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, Corvaglia L, et al. Prophylactic use of a probiotic in the prevention of colic, regurtation, and functional constipation: a randomized clinical trial. JAMA 2014;168:228-33. google scholar
50. Sung V, Hiscock H, Tang MLK, Mensah FK, Nation ML, Satzke C, et al. Treating infant colic with the probiotic lactobacillus reuteri:double blind, placebo controlled randomised trial. BMJ 2014;348:g2107. https://doi.org/10.1136/bmj.g2107 google scholar
51. Bruyas-Bertholon V, Lachaux A, Dubois JP, Fourneret P, Letrilliart L. Which treatments for infantile colics? Presse Med 2012;41:e404-10. google scholar
52. Weizman Z, Alkrinawi S, Goldfarb D, Bitran C. Herbal teas for infantile colic. J Pediatr 1993;123: 670-1. https://doi.org/10.1016/S0022-3476(05)80982-5 google scholar
53. Arikan D, Alp H, Gizem S, Orbak Z, Ciftçi EK. Effectiveness of massage, sucrose solution, herbal tea or hydrolysed formula in the treatment of infantile colic. J Clin Nurs 2008;17:1754-61. https://doi.org/10.1111/j.1365-2702.2007.02093.x google scholar
54. Rodriguez-Gonzalesn M, Benavente Fernandez I, Zafra Rodriguez P, et al. Toxicity of remedies for infantile colic. Arch Dis Child 2014;99:147. google scholar
55. Özden TA, İşsever H, Gokcay G, Saner G. Longitudinal analyses of blood-lead levels and risk factors for lead poisoning in healthy children under two years of age indoor built environ 2004;13:303-8. google scholar
56. Tikochinski Y, Kukliansky I. Examination of the effect of born free active flow baby bottles on infant colic. Gastroenterol Nurs 2013;36:123-7. https://doi.org/10.1097/SGA.0b013e318288d13a google scholar
57. Ohgi S, Akiyama T, Arisawa K, Shigermori K. Randomised controlled trial of swaddling versus massage in the management of excessive crying in infants with cerebral injuries. Arch Dis Child 2004;89:212-6. https://doi.org/10.1136/adc.2002.025064 google scholar
58. Esposito G, Yoshida S, Ohnishi R, Tsuneoka Y, Rostagno MC, Yokota S, et al. Infant calming responses during maternal carrying in humans and mice. Curr Çocuk Dergisi 17(2):53-60, 2017 60 Biol 2013;23:739-45. https://doi.org/10.1016/j.cub.2013.03.041 google scholar
59. Epple A. Infant massage for children with disabilities and special needs. Pract Midwife 2011;14:30-32. google scholar
60. Underdown A, Barlow J, Chung V, Stewart-Brown S. Massage intervention for promoting mental and physical health in infants aged under six months. Cochrane Database Syst Rev 2006;18:CD005038. https://doi.org/10.1002/14651858.cd005038.pub2 google scholar
61. Dobson D, Lucassen PL, Miller JJ, Vlieger AM, Prescott P, Lewith G. Manipulative therapies for infantile colic. Cochrane Database Syst Rev 2012;12: CD004796. https://doi.org/10.1002/14651858.cd004796.pub2 google scholar
62. Landgren K, Kvorning N, Hallstrom I. Acupuncture reduces crying in infants with infantile colic: a randomized, controlled, blind clinical study. Acupunct Med 2010;28:174-9. https://doi.org/10.1136/aim.2010.002394 google scholar
63. Savino F, Castagno E, Bretto R, Brondello C, Palumeri E, Oggero R. A prospective 10-year study on children who had severe infantile colic. Acta Paediatr Suppl 2005;94:129-32. https://doi.org/10.1080/08035320510043691 google scholar
64. Kaymaz N, Uzun ME, Cevizci S, Yıldırım S, Ilcin M, Topaloğlu N, et al. Attention deficit and hyperactivity disorder and infantile colic. Minerva Pediatr 2015; 67:391-9. google scholar
65. Romanello S, Spiri D, Marcuzzi E, Zanin A, Boizeau P, Riviere S, et al. Association between childhood migraine and history of infantile colic. JAMA 2013;309: 1607-12. https://doi.org/10.1001/jama.2013.747 google scholar
66. Gelfand AA, Goadsby PJ, Allen IE. The relationship between migraine and infant colic: a systematic review and meta-analysis. Cephalalgia 2015;35:63-72. https://doi.org/10.1177/0333102414534326 google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format

EXPORT

APA

Karabayır, N., & Gökçay, E.G. (0001). Eski Soruna Yeni Bir Bakış: İnfantil Kolik. Journal of Child, 17(2), 53-60. https://doi.org/10.5222/j.child.2017.053

AMA

Karabayır N, Gökçay E G. Eski Soruna Yeni Bir Bakış: İnfantil Kolik. Journal of Child. 0001;17(2):53-60. https://doi.org/10.5222/j.child.2017.053

ABNT

Karabayır, N.; Gökçay, E.G. Eski Soruna Yeni Bir Bakış: İnfantil Kolik. Journal of Child, [Publisher Location], v. 17, n. 2, p. 53-60, 0001.

Chicago: Author-Date Style

Karabayır, Nalan, and Emine Gülbin Gökçay. 0001. “Eski Soruna Yeni Bir Bakış: İnfantil Kolik.” Journal of Child 17, no. 2: 53-60. https://doi.org/10.5222/j.child.2017.053

Chicago: Humanities Style

Karabayır, Nalan, and Emine Gülbin Gökçay. “Eski Soruna Yeni Bir Bakış: İnfantil Kolik.” Journal of Child 17, no. 2 (Oct. 2024): 53-60. https://doi.org/10.5222/j.child.2017.053

Harvard: Australian Style

Karabayır, N & Gökçay, EG 0001, 'Eski Soruna Yeni Bir Bakış: İnfantil Kolik', Journal of Child, vol. 17, no. 2, pp. 53-60, viewed 6 Oct. 2024, https://doi.org/10.5222/j.child.2017.053

Harvard: Author-Date Style

Karabayır, N. and Gökçay, E.G. (0001) ‘Eski Soruna Yeni Bir Bakış: İnfantil Kolik’, Journal of Child, 17(2), pp. 53-60. https://doi.org/10.5222/j.child.2017.053 (6 Oct. 2024).

MLA

Karabayır, Nalan, and Emine Gülbin Gökçay. “Eski Soruna Yeni Bir Bakış: İnfantil Kolik.” Journal of Child, vol. 17, no. 2, 0001, pp. 53-60. [Database Container], https://doi.org/10.5222/j.child.2017.053

Vancouver

Karabayır N, Gökçay EG. Eski Soruna Yeni Bir Bakış: İnfantil Kolik. Journal of Child [Internet]. 6 Oct. 2024 [cited 6 Oct. 2024];17(2):53-60. Available from: https://doi.org/10.5222/j.child.2017.053 doi: 10.5222/j.child.2017.053

ISNAD

Karabayır, Nalan - Gökçay, EmineGülbin. “Eski Soruna Yeni Bir Bakış: İnfantil Kolik”. Journal of Child 17/2 (Oct. 2024): 53-60. https://doi.org/10.5222/j.child.2017.053

Volume 17, Issue 22017, P. 53-60

TIMELINE

Submitted	26.02.2017
Accepted	31.05.2017

LICENCE

Attribution-NonCommercial (CC BY-NC)

This license lets others remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.

Journal of Child

Review

Eski Soruna Yeni Bir Bakış: İnfantil Kolik

New Perspective to the Old Problem: Infantile Colic

PDF View

References

Citations

EXPORT

APA

AMA

ABNT

Chicago: Author-Date Style

Chicago: Humanities Style

Harvard: Australian Style

Harvard: Author-Date Style

MLA

Vancouver

ISNAD

TIMELINE

LICENCE

SHARE