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DOI :10.26650/jchild.2025.1645002   IUP :10.26650/jchild.2025.1645002    Full Text (PDF)

Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study

Mustafa Törehan Aslan, Hasan Tolga Çelik

Objective: To conduct a bibliometric analysis on stem cell therapy in neonates, identifying key trends, prolific authors, influential institutions, and research collaborations to provide a structured overview of the field’s development.

Methods: A bibliometric approach was employed, analyzing the literature indexed in major academic databases (Web of Science, Scopus, and PubMed). Publications between 2000 and 2024 were retrieved using specific keywords related to neonatal stem cell therapy. Data analysis was performed using VOSviewer and Microsoft Excel to evaluate publication trends, citation metrics, authorship networks, keyword co-occurrences, and geographical distribution.

Results: A total of 585 relevant articles were identified, with a significant increase in publication output observed over the last decade. The most researched neonatal condition was HIE, followed by BPD and NEC. Mesenchymal stem cells (MSCs) emerged as the most studied stem cell type. The United States, China, and Europe accounted for most publications, while low- and middle-income countries had minimal contributions, highlighting global research disparities. Citation analysis revealed the most influential studies as preclinical and early-phase clinical trials. Emerging trends include the integration of bioengi neered scaffolds, organoid models, artificial intelligence, and gene-editing techniques in neonatal stem cell research. Conclusions: The bibliometric analysis demonstrates a growing research interest in neonatal stem cell therapy, with a focus on HIE, BPD, and NEC. Despite significant advancements, challenges remain in terms of clinical translation, ethical considerations, and global accessibility. Future research should emphasize large-scale clinical trials, cross-disciplinary collaborations, and equitable distribution of research efforts to ensure that stem cell therapies benefit neonates worldwide.

Keywords: Neonatal stem cell therapy, bibliometric analysis, hypoxic-ischemic encephalopathy, bronchopulmonary dysplasia, necrotizing enterocolitis, mesenchymal stem cells

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APA

Aslan, M.T., & Çelik, H.T. (2025). Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study. Journal of Child, 25(1), 44-51. https://doi.org/10.26650/jchild.2025.1645002


AMA

Aslan M T, Çelik H T. Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study. Journal of Child. 2025;25(1):44-51. https://doi.org/10.26650/jchild.2025.1645002


ABNT

Aslan, M.T.; Çelik, H.T. Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study. Journal of Child, [Publisher Location], v. 25, n. 1, p. 44-51, 2025.


Chicago: Author-Date Style

Aslan, Mustafa Törehan, and Hasan Tolga Çelik. 2025. “Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study.” Journal of Child 25, no. 1: 44-51. https://doi.org/10.26650/jchild.2025.1645002


Chicago: Humanities Style

Aslan, Mustafa Törehan, and Hasan Tolga Çelik. “Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study.” Journal of Child 25, no. 1 (Aug. 2025): 44-51. https://doi.org/10.26650/jchild.2025.1645002


Harvard: Australian Style

Aslan, MT & Çelik, HT 2025, 'Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study', Journal of Child, vol. 25, no. 1, pp. 44-51, viewed 12 Aug. 2025, https://doi.org/10.26650/jchild.2025.1645002


Harvard: Author-Date Style

Aslan, M.T. and Çelik, H.T. (2025) ‘Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study’, Journal of Child, 25(1), pp. 44-51. https://doi.org/10.26650/jchild.2025.1645002 (12 Aug. 2025).


MLA

Aslan, Mustafa Törehan, and Hasan Tolga Çelik. “Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study.” Journal of Child, vol. 25, no. 1, 2025, pp. 44-51. [Database Container], https://doi.org/10.26650/jchild.2025.1645002


Vancouver

Aslan MT, Çelik HT. Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study. Journal of Child [Internet]. 12 Aug. 2025 [cited 12 Aug. 2025];25(1):44-51. Available from: https://doi.org/10.26650/jchild.2025.1645002 doi: 10.26650/jchild.2025.1645002


ISNAD

Aslan, MustafaTörehan - Çelik, HasanTolga. “Mapping the Scientific Output of Stem Cell Therapy in Neonates: A Bibliometric Study”. Journal of Child 25/1 (Aug. 2025): 44-51. https://doi.org/10.26650/jchild.2025.1645002



TIMELINE


Submitted22.02.2025
Accepted26.03.2025
Published Online08.07.2025

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