Journal of Child

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DOI :10.26650/jchild.2023.1231820   IUP :10.26650/jchild.2023.1231820    Full Text (PDF)

Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria

Olayinka Rasheed Ibrahım, Olajide Aladesua, Michael Abel Alao, Abdurrazzaq Alege

Objective: Studies on acute glomerulonephritis (AGN) in Nigeria described the epidemiological profile without an in-depth analysis of variables associated with outcomes. Herein, we describe the profile and factors associated with hospitalization outcomes (discharge or death) among childhood AGNs at a health facility in northwestern Nigeria.

Material and Methods: This prospective cross-sectional study was conducted between 1st January 2018 and 31st December 2019 at a tertiary health facility in northwestern Nigeria. The diagnosis of AGN was based on a clinical diagnosis. We also obtained relevant history, clinical, and laboratory features.

Results: Thirty-five children were admitted with AGN during the study period. The mean age was 7.7 ± 3.3 years. Most were aged 5 to 10 years (23; 65.7%), male (60.0%), and from a lower socio-economic class (77.2%). The annual incidence of AGN was 11 cases per 1000 children. The most common clinical presentations were generalized body swelling (100.0%), reduced urine output (85.7%), and hypertension (74.3%). The medians (interquartile range) of urea and creatinine were 10.0 (4.50 to 23.90) mmol/L and 85 (67.60 to 204.00) µmol/L, respectively. Among the clinical features, only fever was associated with outcomes, while serum urea and creatinine levels were significantly higher among non-survivors, p<0.05. We recorded four deaths (case fatality rate of 11.4%), two each from congestive cardiac failure and hypertensive encephalopathy.

Conclusion: This study shows a high incidence of childhood AGN and mortality in Katsina, northwestern Nigeria. Fever was associated with outcomes, while serum creatinine and urea levels were elevated among non-survivors.

Keywords: Child, Acute Glomerulonephritis, Outcomes, Nigeria

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APA

Ibrahım, O.R., Aladesua, O., Alao, M.A., & Alege, A. (2023). Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria. Journal of Child, 23(4), 327-333. https://doi.org/10.26650/jchild.2023.1231820


AMA

Ibrahım O R, Aladesua O, Alao M A, Alege A. Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria. Journal of Child. 2023;23(4):327-333. https://doi.org/10.26650/jchild.2023.1231820


ABNT

Ibrahım, O.R.; Aladesua, O.; Alao, M.A.; Alege, A. Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria. Journal of Child, [Publisher Location], v. 23, n. 4, p. 327-333, 2023.


Chicago: Author-Date Style

Ibrahım, Olayinka Rasheed, and Olajide Aladesua and Michael Abel Alao and Abdurrazzaq Alege. 2023. “Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria.” Journal of Child 23, no. 4: 327-333. https://doi.org/10.26650/jchild.2023.1231820


Chicago: Humanities Style

Ibrahım, Olayinka Rasheed, and Olajide Aladesua and Michael Abel Alao and Abdurrazzaq Alege. “Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria.” Journal of Child 23, no. 4 (Apr. 2024): 327-333. https://doi.org/10.26650/jchild.2023.1231820


Harvard: Australian Style

Ibrahım, OR & Aladesua, O & Alao, MA & Alege, A 2023, 'Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria', Journal of Child, vol. 23, no. 4, pp. 327-333, viewed 28 Apr. 2024, https://doi.org/10.26650/jchild.2023.1231820


Harvard: Author-Date Style

Ibrahım, O.R. and Aladesua, O. and Alao, M.A. and Alege, A. (2023) ‘Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria’, Journal of Child, 23(4), pp. 327-333. https://doi.org/10.26650/jchild.2023.1231820 (28 Apr. 2024).


MLA

Ibrahım, Olayinka Rasheed, and Olajide Aladesua and Michael Abel Alao and Abdurrazzaq Alege. “Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria.” Journal of Child, vol. 23, no. 4, 2023, pp. 327-333. [Database Container], https://doi.org/10.26650/jchild.2023.1231820


Vancouver

Ibrahım OR, Aladesua O, Alao MA, Alege A. Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria. Journal of Child [Internet]. 28 Apr. 2024 [cited 28 Apr. 2024];23(4):327-333. Available from: https://doi.org/10.26650/jchild.2023.1231820 doi: 10.26650/jchild.2023.1231820


ISNAD

Ibrahım, OlayinkaRasheed - Aladesua, Olajide - Alao, MichaelAbel - Alege, Abdurrazzaq. “Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria”. Journal of Child 23/4 (Apr. 2024): 327-333. https://doi.org/10.26650/jchild.2023.1231820



TIMELINE


Submitted10.01.2023
Accepted26.05.2023
Published Online20.12.2023

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