Research Article


DOI :10.26650/jchild.2021.782119   IUP :10.26650/jchild.2021.782119    Full Text (PDF)

Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract

Duygu Övünç Hacıhamdioğlu

Objective: The objective of the study was to determine the course of the clinical and biochemical profile of children with congenital anomalies of the kidneys and urinary tracts (CAKUT).

Material and Method: The files of the patients who were followed up with the diagnosis of CAKUT in the Pediatric Nephrology Clinic between February 2016 and September 2017 in the Süleymaniye Maternity and Pediatrics Hospital were analyzed retrospectively.

Results: Sixty five of 117 patients followed up for CAKUT were included in the study. In this study, we found that of the patients, 29.2% were diagnosed antenatally, 27.7% had comorbid disease, and 32.2% had family kidney disease history. Comparing with postnatal diagnosis, the patients who had pretnatal diagnosis had lower eGFR after follow up (p=0.048). There is a statistically significant relationship between consanguineous marriage and comorbidity (p=0.047, x2=3.94).

Conclusion: It would be better to follow up the patients with consanguinity, family kidney disease and comorbidity closely even though they have compensatory hypertrophy.

DOI :10.26650/jchild.2021.782119   IUP :10.26650/jchild.2021.782119    Full Text (PDF)

Konjenital Böbrek ve İdrar Yolu Anomalisi Olan Çocukların Tek Merkezli Retrospektif Kohort Analizi

Duygu Övünç Hacıhamdioğlu

Amaç: Çalışmada konjenital böbrek ve idrar yolu anomalisi olan çocukların retrospektif epidemiyolojik, demografik ve klinik özelliklerinin paylaşılması amaçlanmıştır.

Gereç ve Yöntem: Süleymaniye Kadın Doğum ve Çocuk Hastalıkları Hastanesi’nde Şubat 2016-Eylül 2017 tarihleri arasında Çocuk Nefroloji Kliniği’nde konjenital böbrek ve idrar yolu anomalisi tanısı ile takip edilen hastaların dosyaları geriye dönük olarak incelendi.

Bulgular: Konjenital böbrek ve idrar yolu anomalisi nedeniyle takip edilen 117 hastadan 65’i çalışmaya dahil edildi. Bu kohortta prenatal tanı %29,2 (19), ek hastalık %27,7 (18), ailede böbrek hastalığı %32,2 (21), kompensatuvar hipertrofi %53,8 (35) ve %9,2 (6) hipertansiyon saptanmıştır.

Sonuç: Akrabalık, aile böbrek hastalığı ve komorbiditesi olan hastaların kompensatuvar hipertrofisi olsa bile daha yakın takibi daha iyi olacaktır.



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References

  • 1. Murugapoopathy V, Gupta IR. A Primer on Congenital Anomalies of the Kidneys and Urinary Tracts (CAKUT). Clin J Am Soc Nephrol 2020May7;15(5):723-31. Doi:10.2215/CJN.12581019. google scholar
  • 2. Süleymanlar G, Ateş K, Seyahi N. Registry of the nephrology, dialysis and transplantation in Turkey T.C. Sağlik Bakanliği ve Türk Nefroloji Derneği ortak raporu Ankara 2019 ISBN 978-605-62465-0-0 http://www.nefroloji.org.tr/folders/file/REGISTRY_2018.pdf (last enterance April 2021). google scholar
  • 3. Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, et al., American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee. Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment: a scientific statement from the American Heart Association. Atherosclerosis, Hypertension, and Obesity in Youth Committee of the council on cardiovascular disease in the young and the council for high blood pressure research. Hypertension 2008:52(3):433-51. https://doi.org/10.1161/HYPERTENSIONAHA.108.190329. google scholar
  • 4. Schwartz GJ,Munoz A, SchneiderMF, Mak RH, Kaskel F,Warady BA, et al. New equations to estimate GFR in children with CKD. J Am Soc Nephrol 2009:20:629–37. Doi: https://doi.org/10.1681/ASN.2008030287. google scholar
  • 5. Cheng CH, Tsai MH, Huang YC, Lin-Hui Su, Yong-Kwei Tsau, Chi-Jen Lin et al. Antibiotic resistance patternsof community-acquired urinary tract infections in children with vesicoureteral reflux receivingprophylactic antibiotic therapy. Pediatrics 2008;122:1212. Doi: https://doi.org/10.1542/peds.2007-2926. google scholar
  • 6. Chand DH, Rhoades T, Poe SA, Kraus S, Strife CF. Incidence and severity of vesicoureteral reflux in children related to age, gender, race and diagnosis. J Urol 2003;170:1548. /doi.org/10.1097/01.ju.0000084299.55552.6c. google scholar
  • 7. Yürük Yıldırım ZN. Konjenital Böbrek Anomalileri. Çocuk Dergisi 2013;13(4):141-6. Doi: 10.5222/j .child.2013.141. google scholar
  • 8. Güngör H, Bek K, Çelakıl ME, Ekinci Z. Congenital Anomalies of Kidney and Urinary Tract (CAKUT): Single Center Experience for 14 Years. JCP 2019;17(1):45-57. Doi: 10.32941/pediatri.544470. google scholar
  • 9. Gemici A, Atmış B, Ergün R. Congenital Kidney and Urinary Tract Anomalies In Children(CAKUT); Single Center Experience. Med J West Black Sea 2019;3(3):93-100. Doi: 10.29058/mjwbs.2019.3.3. google scholar
  • 10. A. M. Elmacı ve F. Akın. Clinical and demographic characteristics of children with congenital anomaly of kidney and urinary tract. Dicle Medical Journal 2014;41(2):309-12. Doi: 10.5798/diclemedj.0921.2014.02.0422. google scholar

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APA

Övünç Hacıhamdioğlu, D. (2021). Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract. Journal of Child, 21(1), 21-25. https://doi.org/10.26650/jchild.2021.782119


AMA

Övünç Hacıhamdioğlu D. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract. Journal of Child. 2021;21(1):21-25. https://doi.org/10.26650/jchild.2021.782119


ABNT

Övünç Hacıhamdioğlu, D. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract. Journal of Child, [Publisher Location], v. 21, n. 1, p. 21-25, 2021.


Chicago: Author-Date Style

Övünç Hacıhamdioğlu, Duygu,. 2021. “Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract.” Journal of Child 21, no. 1: 21-25. https://doi.org/10.26650/jchild.2021.782119


Chicago: Humanities Style

Övünç Hacıhamdioğlu, Duygu,. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract.” Journal of Child 21, no. 1 (May. 2024): 21-25. https://doi.org/10.26650/jchild.2021.782119


Harvard: Australian Style

Övünç Hacıhamdioğlu, D 2021, 'Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract', Journal of Child, vol. 21, no. 1, pp. 21-25, viewed 5 May. 2024, https://doi.org/10.26650/jchild.2021.782119


Harvard: Author-Date Style

Övünç Hacıhamdioğlu, D. (2021) ‘Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract’, Journal of Child, 21(1), pp. 21-25. https://doi.org/10.26650/jchild.2021.782119 (5 May. 2024).


MLA

Övünç Hacıhamdioğlu, Duygu,. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract.” Journal of Child, vol. 21, no. 1, 2021, pp. 21-25. [Database Container], https://doi.org/10.26650/jchild.2021.782119


Vancouver

Övünç Hacıhamdioğlu D. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract. Journal of Child [Internet]. 5 May. 2024 [cited 5 May. 2024];21(1):21-25. Available from: https://doi.org/10.26650/jchild.2021.782119 doi: 10.26650/jchild.2021.782119


ISNAD

Övünç Hacıhamdioğlu, Duygu. Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract”. Journal of Child 21/1 (May. 2024): 21-25. https://doi.org/10.26650/jchild.2021.782119



TIMELINE


Submitted18.08.2020
First Revision05.11.2020
Last Revision04.02.2021
Accepted26.02.2021
Published Online17.05.2021

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