Journal of Child

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DOI :10.5222/j.child.2015.16   IUP :10.5222/j.child.2015.16    Full Text (PDF)

Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience

Sinan Tüfekci, Emine Asuman Çoban, Beril Yaşa, Meltem Bor, Mehmet Barburoğlu, Serra Sencer, Elmas Zeynep İnce

Objective: To assess the clinical features, diagnosis, management strategies and results of newborns born between the years 2005-2015 with Vein of Galen Malformation (VGAM). Material and Method: Eight newborn patients with diagnosis of VGAM were assessed retrospectively in terms of clinical admission symptoms, diagnosis, treatment strategies and follow-up based on the information retrieved from patient files. Three of four patients who survived had neurological assessment while the information about the remaining patient whose family moved to another city were obtained via phone call. Results: Seven out of 8 patients (1 female, and 7 male patients) had antenatal diagnosis. In all cases severe heart failure and pulmonary hypertension were present from the first days of their life, later on development of hypotension, multiorgan failure, hydrocephalus and seizures was seen. VGAM and its feeder arteries were mapped by cranial magnetic resonance imaging and magnetic resonance angiography. Transarterial embolization therapy was performed successfully in four patients. Despite similar treatment modalities three of these patients died, and one patient was lost before initiation of embolization procedure. Conclusion: VGAM has high mortality and morbidity rates because of its complicated anatomy, pathophysiology leading to severe neurological sequelae. Prognosis in high risk neonates can be improved with aggressive medical support and early endovascular embolization therapy.

Keywords: High-outflow heart failure, endovascular therapy, vein of Galen aneurysmal malformation, neonate
DOI :10.5222/j.child.2015.16   IUP :10.5222/j.child.2015.16    Full Text (PDF)

Yenidoğanda Galen Veni Anevrizmal Malformasyonlu Vakaların Radyolojik ve Klinik Özellikleri, Endovasküler Tedavi Yönetimi: On Yıllık Deneyim

Sinan Tüfekci, Emine Asuman Çoban, Beril Yaşa, Meltem Bor, Mehmet Barburoğlu, Serra Sencer, Elmas Zeynep İnce

Amaç: Galen veni anevrizmal malformasyonu (GVAM) tanısı ile 2005-2015 yılları arasında izlenen yenidoğanların klinik özellikleri, tanı, tedavi yaklaşımı ve sonuçlarını değerlendirmek. Gereç ve Yöntem: GVAM tanısı alan 8 hastanın klinik başvuru, izlem, tanı ve tedavi yaklaşımı retrospektif olarak dosya kayıtlarından elde edilddi. Yaşayan 4 hastadan 3’ünün nörolojik izlemi değerlendirildi, diğer vaka ile ilgili bilgiler ailenin başka şehire taşınmasından dolayı telefon ile görüşülerek elde edildi. Bulgular: Merkezimizde tedavi edilen sekiz hastadan yedisinin (erkek 7, kız 1) antenatal tanısı vardı. Vakaların klinik izleminde ilk günlerde ağır kalp yetersizliği ve pulmoner hipertansiyon sık olup, daha sonra hipotansiyon, çoklu organ yetersizliği, hidrosefali ve konvülsiyon geliştiği görüldü. Hastalarda MR görüntüleme ve MR anjiyografi ile GVAM ve besleyici damar haritası gösterildi. Dört vaka transarteriyel embolizasyon tedavisi ile başarılı olarak tedavi edildi. Benzer tedavi metodlarına rağmen, üç vaka kaybedildi, bir hasta embolizasyon işlemi yapılamadan kaybedildi. Sonuç: GVAM karmaşık anatomi, patofizyoloji, ciddi nörolojik sekele yol açan özelliği ile yüksek mortalite ve morbiditeye sahiptir. Agresif tıbbi destek ve erken endovasküler embolizasyon tedavisi ile yüksek riskli yenidoğanlarda da prognoz iyileştirilebilir.

Keywords: Yüksek debili kalp yetersizliği, endovasküler tedavi, galen ven anevrizmal malformasyonu, yenidoğan

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APA

Tüfekci, S., Çoban, E.A., Yaşa, B., Bor, M., Barburoğlu, M., Sencer, S., & İnce, E.Z. (2015). Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience. Journal of Child, 15(1), 16-23. https://doi.org/10.5222/j.child.2015.16


AMA

Tüfekci S, Çoban E A, Yaşa B, Bor M, Barburoğlu M, Sencer S, İnce E Z. Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience. Journal of Child. 2015;15(1):16-23. https://doi.org/10.5222/j.child.2015.16


ABNT

Tüfekci, S.; Çoban, E.A.; Yaşa, B.; Bor, M.; Barburoğlu, M.; Sencer, S.; İnce, E.Z. Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience. Journal of Child, [Publisher Location], v. 15, n. 1, p. 16-23, 2015.


Chicago: Author-Date Style

Tüfekci, Sinan, and Emine Asuman Çoban and Beril Yaşa and Meltem Bor and Mehmet Barburoğlu and Serra Sencer and Elmas Zeynep İnce. 2015. “Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience.” Journal of Child 15, no. 1: 16-23. https://doi.org/10.5222/j.child.2015.16


Chicago: Humanities Style

Tüfekci, Sinan, and Emine Asuman Çoban and Beril Yaşa and Meltem Bor and Mehmet Barburoğlu and Serra Sencer and Elmas Zeynep İnce. “Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience.” Journal of Child 15, no. 1 (Jun. 2025): 16-23. https://doi.org/10.5222/j.child.2015.16


Harvard: Australian Style

Tüfekci, S & Çoban, EA & Yaşa, B & Bor, M & Barburoğlu, M & Sencer, S & İnce, EZ 2015, 'Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience', Journal of Child, vol. 15, no. 1, pp. 16-23, viewed 5 Jun. 2025, https://doi.org/10.5222/j.child.2015.16


Harvard: Author-Date Style

Tüfekci, S. and Çoban, E.A. and Yaşa, B. and Bor, M. and Barburoğlu, M. and Sencer, S. and İnce, E.Z. (2015) ‘Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience’, Journal of Child, 15(1), pp. 16-23. https://doi.org/10.5222/j.child.2015.16 (5 Jun. 2025).


MLA

Tüfekci, Sinan, and Emine Asuman Çoban and Beril Yaşa and Meltem Bor and Mehmet Barburoğlu and Serra Sencer and Elmas Zeynep İnce. “Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience.” Journal of Child, vol. 15, no. 1, 2015, pp. 16-23. [Database Container], https://doi.org/10.5222/j.child.2015.16


Vancouver

Tüfekci S, Çoban EA, Yaşa B, Bor M, Barburoğlu M, Sencer S, İnce EZ. Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience. Journal of Child [Internet]. 5 Jun. 2025 [cited 5 Jun. 2025];15(1):16-23. Available from: https://doi.org/10.5222/j.child.2015.16 doi: 10.5222/j.child.2015.16


ISNAD

Tüfekci, Sinan - Çoban, EmineAsuman - Yaşa, Beril - Bor, Meltem - Barburoğlu, Mehmet - Sencer, Serra - İnce, ElmasZeynep. “Radiological and Clinical Features of Vein of Galen Aneurysmal Malformation in Newborn, Endovascular Interventional Treatment Method: 10 Years Experience”. Journal of Child 15/1 (Jun. 2025): 16-23. https://doi.org/10.5222/j.child.2015.16



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Published Online30.04.2015

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