Journal of Istanbul Faculty of Medicine

SUBMITINFORMATION
EnglishTürkçe

Review


DOI :https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57   IUP :https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57    Full Text (PDF)

Management lymphadenopathy in childhood.

Muhammet Ali Varkal, İsmail Yıldız, Emin Ünüvar

Lymphadenopathy is a common symptom in children. Although, the most common causes are infection and autoimmune diseases, most dangerous are malignancies. It can be local or generalized. In local lymphadenopaties infections are prominent causes but in generalized forms systemic diseases should be considered. The rate of malignancy is 1-3 % and lymphomas are most common. Ultrasonography can be helpful with some of the findings to the physician for differential diagnosis and malignancy. If diagnosis could not be confirmed or malignancy is suspected, biopsy is essential. 

Keywords: Inflammatory breast cancer, Mucinous breast cancer, Mammography
DOI :https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57   IUP :https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57    Full Text (PDF)

ÇOCUKLUK ÇAĞINDA LENFADENOPATİYE YAKLAŞIM

Muhammet Ali Varkal, İsmail Yıldız, Emin Ünüvar

Lymphadenopathy is a common symptom in children. Although, the most common causes are infection and autoimmune diseases, most dangerous are malignancies. It can be local or generalized. In local lymphadenopaties infections are prominent causes but in generalized forms systemic diseases should be considered. The rate of malignancy is 1-3 % and lymphomas are most common. Ultrasonography can be helpful with some of the findings to the physician for differential diagnosis and malignancy. If diagnosis could not be confirmed or malignancy is suspected, biopsy is essential.

Keywords: İnflamatuar meme kanseri, Müsinöz meme kanseri, Mammografi

PDF View

References

  • 1.Abdel-Aziz M, El-Hoshy H, Rashed M, Qotb M, Awad S, Naguib N. Epstein–Barr virus infection as a cause of cervical lymphadenopathy in children. Int J Pediatr Otorhinolaryngol 2011;75: 564–7. google scholar
  • 2. Ahuja AT. Ying M. Grey scala sonography in assesment of cervical lymphadenopathy: review of sonographic appearances and features that may help a beginner. Br J Oral Maxillofac Surg 2000;38: 451- 9. google scholar
  • 3. Akyüz C. Lenfadenopatili çocuğa yaklaşım. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Sempozyumu 2006; 49: 17-28. google scholar
  • 4. Alison MF. Evaluation and management of lymphadenopathy in children. Pediatr Rev 2008;29: 53-60. google scholar
  • 5. Almasri M, Papa A, Souliou E, Haidopoulou K, Eboriadou M. Respiratory syncytial virus infection in hospitalized children older than 2 years with community-acquired pneumonia. Hippokratia 2013;17:146-9. google scholar
  • 6. Banks P.M. Technical factors in the preparation and evulation of lymph node biopsies. In: Daniel M. Knowles (eds). Neoplastic hematopathology, Lippincott Williams & Wilkins. Philadelphia, USA, second edition. 2001;467-83. google scholar
  • 7. Baytan B, Güneş A.M, Günay Ü. Çocukluk Çağında Lenfadenomegaliler. Güncel Pediatri 2006; 2: 49-51. google scholar
  • 8. Chen J et al. Kinetics of IgG antibody to cytomegalovirus (CMV) after birth and seroprevalence of anti-CMV IgG in Chinese children. Virol J, 2012;304:1-7. google scholar
  • 9. Çaklı H, Küçük S, Bildirici K, Cingi E, Özüdoğru E. Rosai-Dorfman Hastalğı (Masif Lenfadenopatili Sinüs Histiositozis): Olgu Sunumu. Turk Arch Otolaryngol 2003;41:110-5. google scholar
  • 10. Devecioğlu Ö, Yalman N, Biner B et al. Reactivation: a severe problem in familial hemophagocytic lymphohistiocytosis. Pediatr Int 2002;44:1035-55. google scholar
  • 11. Gosche JR, Vick L. Acute, subacute, and chronic cervical lymphadenitis in children. Semin Pediatr Surg 2006;15:99-106. google scholar
  • 12. Gülez ve ark. Kikuchi - Fujimoto hastalığı ile birlikte hemofagositik sendrom. Turk Arch Ped 2013;48:71-3. google scholar
  • 13. Hatipoğlu E ve ark. Servikal Lenfadenomegalili Olgularda Renkli Doppler Ultrasonografi Bulgularının Değerlendirilmesi ve Histopatolojik Korelasyonu. Bakırkoy Tıp Dergisi 2008;4:14-9. google scholar
  • 14. Kantar M, Kadıoğlu M, Hekimgil M, Soydan S, Aksoylar S, Çetingül N ve ark. Çocuklarda lenfadenopati ayırıcı tanısında seyrek görülen bir durum: Kikuchi - Fujimoto hastalığı. Çocuk Sağlığı ve Hastalıkları Dergisi 2008;51:153-7. google scholar
  • 15. Karataş S. Çocukluk Çağında Malignite Kuşkulu Periferal Lenfadenopatili Hastalarda Tanı Ve İzlem Sürecinin Değerlendirilmesi. Kocaeli Üniversitesi Uzmanlık Tezi 2009. google scholar
  • 16. Keleş ve ark. Periyodik Ateş Sendromları. J Curr Ped 2007;57-61. google scholar
  • 17. Kumral A. Çocukluk çağı periferal lenfadenopatileri. Dokuz Eylül Üniversitesi, Uzmanlık Tezi, 1999. 18. Lanzkowsky P. Lymphadenopathy and Splenomegaly. In: Philip Lanzkowsky (ed). Manual of Pediatric Hematology and Oncology, Elsevier Academic Pres. New York, USA, 5th ed. 2011;463- 8. google scholar
  • 19. Lavrence MW, Pitts W. The role of fine needle aspiration biopsy in the diagnosis and management of hemotopetic neolasma. In: Daniel M. Knowles (eds). Neoplastic hematopathology, Lippincott Williams & Wilkins. Philadelphia, USA, second edition. 2001;483-507. google scholar
  • 20. Leung AK, Robson WL. Childhood cervical lymphadenopathy. J Pediatr Health Care 2004; 18: 3-7. google scholar
  • 21. Link MP, Donaldson SS. The Lymphomas and Lymphadenopathy. In: Nathan DA, Oski FA (eds). Nathan and Oski’s Hemotology of infancy and childhood, WB Sounders. Philadelphia, USA, 6 th ed. 2003:1192-6. google scholar
  • 22. Newman K, Hayes-Jordan AA. Lymph Node Disorders. In: Grosfeld JL, O’Neil JA, Fonkalsrud EW, Coran AG ( eds). Pediatric Surgery, Mosby Elsevier, Philadelphia, USA, 6 th ed. 2006: p.844-9. google scholar
  • 23. Nield LS, Kamat D. Lymphadenopathy in Children: When and How to Evaluate. Clin Pediatr 2004;43: 25-33. google scholar
  • 24. Nolder AR. Paediatric cervical lymphadenopathy: When to biopsy. Curr Opin Otolaryngol Head Neck Surg 2013;21:567-70. google scholar
  • 25. Oguz A. Çocukluk çağındaki periferal lenfadenopatiler. Sürekli Tıp Egitim Dergisi 1993;2: 335-9. google scholar
  • 26. Oguz A, Karadeniz C, Temel EA, Citak EC, Okur FV. Evaluation of peripheral lymphadenopathy in children. Pediatr Hematol Oncol. 2006;23:549-61. google scholar
  • 27. Olgun N. Çocukluk Çağı Lenf Bezleri, Lenfadenopatiler ve Yaklaşım. İrken G, Özkan H, Aydın A, (ed). Pediatri Kliniğe Giriş, Tibyan yayıncılık. İzmir. 2001;71-93. google scholar
  • 28. Öksüz RYÇ. Çocukluk çağı periferik lenfadenopatili olguların retrospektif değerlendirilmesi. On dokuz Mayıs Üniversitesi, Uzmanlık tezi, 2008. 29. Özyürek AR, Ülger Z, Levent E, Gürses D. Kawasaki hastalığı: 11 vakanın değerlendirlmesi. Çocuk Sağlığı ve Hastalıkları Dergisi 2004;47:167-71. google scholar
  • 30.Rajasekaran K, Krakovitz P. Enlarged Neck Lymph Nodes in Children. Pediatr Clin North Am 2013;60: 923–36. google scholar
  • 31.Robin G. Kawasaki disease: a review. J Paediatr Health Care 2011;25:379-87. google scholar
  • 32.Rubaltelli L, Proto E, Salmaso R, Bortoletto P, Candiani F, Cagol P. Sonography of abnormal lymph nodes in vitro: correlation of sonographic andhistologic findings. AJR Am J Roentgenol 1990;155:1241-4. google scholar
  • 33. Steinkamp HJ, Maurer J, Cornehl M, Knobber D, Hettwer H, Felix R. Recurrent cervical lymphadenopathy: differential diagnosis with colorduplex sonography. Eur Arch Otorhinolaryngol 1994;251:404-9. google scholar
  • 34. Steinkamp HJ, Rausch M, Mäurer J, Hosten N, Schedel H, Langer R, et al. Color-coded duplex sonography in the differential diagnosis of cervical lymph node enlargements. Rofo 1994;161:226-32. google scholar
  • 35. Stutchfield C.J, Tyrrell J. Evaluation of lymphadenopathy in children. Paediatrics and Child Health. 2011;22:98-102. google scholar
  • 36. Şen M. Çocukluk çağı lenfadenopatilerinin değerlendirilmesi. Selçuk Üniversitesi, Uzmanlık Tezi, 2009. google scholar
  • 37. Tekgül H. Çocukluk çağı periferik lenfadenopatileri, Ege Üniversitesi Tıp Fakültesi, Uzmanlık Tezi, 1993. google scholar
  • 38. Tschammler A, Gunzer U, Reinhart E, et al. The diagnostic asessment of enlarged lymph nodes by qualitative and semiquantative evaluation of lymph node perfusion with colorcoded duplex sonography. Rofo 1991;154:414-8. google scholar
  • 39. Twist CJ, Link MP. Assessment of lymphadenopathy in children. Pediatr Clin North Am 2002;49:1009-25. google scholar
  • 40. Yaris N, Cakir M, Sözen E, Cobanoglu U. Analysis of children with peripheral lymphadenopathy. Clin Pediatr 2006;45:544-9. google scholar
  • 41. Akçakaya N. Akçakaya N. Çocukluk çağı tüberkülozunun tedavisi. İ.Ü. Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri. Erişkin ve Çocukta Tüberküloz Sempozyumu, 30 Nisan 1999, İstanbul, s. 97-103 google scholar
  • 42. Selçuk Kılıç, Murat Yeşilyurt. Tularemi: Güncel Tedavi Seçeneklerine Genel Bir Bakış. Klimik Dergisi 2011;24(1):2-10 google scholar

Citations

Copy and paste a formatted citation or use one of the options to export in your chosen format


EXPORT



APA

Varkal, M.A., Yıldız, İ., & Ünüvar, E. (2015). Management lymphadenopathy in childhood.. Journal of Istanbul Faculty of Medicine, 78(2), 51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


AMA

Varkal M A, Yıldız İ, Ünüvar E. Management lymphadenopathy in childhood.. Journal of Istanbul Faculty of Medicine. 2015;78(2):51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


ABNT

Varkal, M.A.; Yıldız, İ.; Ünüvar, E. Management lymphadenopathy in childhood.. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 78, n. 2, p. 51-57, 2015.


Chicago: Author-Date Style

Varkal, Muhammet Ali, and İsmail Yıldız and Emin Ünüvar. 2015. “Management lymphadenopathy in childhood..” Journal of Istanbul Faculty of Medicine 78, no. 2: 51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


Chicago: Humanities Style

Varkal, Muhammet Ali, and İsmail Yıldız and Emin Ünüvar. “Management lymphadenopathy in childhood..” Journal of Istanbul Faculty of Medicine 78, no. 2 (May. 2025): 51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


Harvard: Australian Style

Varkal, MA & Yıldız, İ & Ünüvar, E 2015, 'Management lymphadenopathy in childhood.', Journal of Istanbul Faculty of Medicine, vol. 78, no. 2, pp. 51-57, viewed 8 May. 2025, https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


Harvard: Author-Date Style

Varkal, M.A. and Yıldız, İ. and Ünüvar, E. (2015) ‘Management lymphadenopathy in childhood.’, Journal of Istanbul Faculty of Medicine, 78(2), pp. 51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57 (8 May. 2025).


MLA

Varkal, Muhammet Ali, and İsmail Yıldız and Emin Ünüvar. “Management lymphadenopathy in childhood..” Journal of Istanbul Faculty of Medicine, vol. 78, no. 2, 2015, pp. 51-57. [Database Container], https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


Vancouver

Varkal MA, Yıldız İ, Ünüvar E. Management lymphadenopathy in childhood.. Journal of Istanbul Faculty of Medicine [Internet]. 8 May. 2025 [cited 8 May. 2025];78(2):51-57. Available from: https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57 doi: https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57


ISNAD

Varkal, MuhammetAli - Yıldız, İsmail - Ünüvar, Emin. “Management lymphadenopathy in childhood.”. Journal of Istanbul Faculty of Medicine 78/2 (May. 2025): 51-57. https://doi.org/https://doi.org/10.18017/iuitfd.d.13056441.2015.78/2.51-57



TIMELINE



SHARE



Istanbul University Press aims to contribute to the dissemination of ever growing scientific knowledge through publication of high quality scientific journals and books in accordance with the international publishing standards and ethics. Istanbul University Press follows an open access, non-commercial, scholarly publishing.