Journal of Istanbul Faculty of Medicine

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Research Article


DOI :10.18017/iuitfd.382761   IUP :10.18017/iuitfd.382761    Full Text (PDF)

PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS

Gonca Bektaş, Edibe Pembegül Yıldız, Tuğçe Aksu Uzunhan, Nur Aydınlı, Meliha Mine Çalışkan, Meral Özmen

Objective: We aimed to define the demographic characteristics, referral symptoms, and neuroimaging findings in children with pseudotumor cerebri syndrome (PTCS) by comparing the differences between idiopathic intracranial hypertension (IIH) (primary PTSS) and secondary PTCS. Materials and Methods: We retrospectively evaluated the medical records and brain imaging findings of children with PTCS who were <18 years of age and were followed by the outpatient clinics of the Department of Child Neurology between January 2011 and January 2016. The children were categorized into two groups: (1) children with IIH and (2) children with secondary PTCS. Results: In total, 26 children were enrolled in the study; group 1 comprised 16 patients, and group 2 comprised 10 patients. In group 2, there were four patients with sinus venous thrombosis, one with autoimmune thyroiditis, one with hypothyroidism, one with Down syndrome, one with pituitary adenomas, and one with pregnancy related PTSS. One patient developed PTSS while receiving growth hormone therapy. At the time of admission, there was no statistically significant difference between the two groups in terms of age, prepubertal/postpubertal patient ratio, headache, double vision, visual disturbance/ loss and presence of nausea/vomiting (p > 0.05). Positive radiological findings were not statistically different between the two groups (p > 0.05). Conclusion: In children with PTSS, the symptoms at onset and brain imaging findings were found to be similar between primary and secondary PTSS.

Keywords: Child, pseudotumor cerebri, idiopathic intracranial hypertension
DOI :10.18017/iuitfd.382761   IUP :10.18017/iuitfd.382761    Full Text (PDF)

ÇOCUKLUK ÇAĞINDA PRİMER VE SEKONDER PSÖDOTÜMÖR SEREBRİ SENDROMU-BAŞVURU SEMPTOMLARI VE BEYİN GÖRÜNTÜLEME BULGULARI

Gonca Bektaş, Edibe Pembegül Yıldız, Tuğçe Aksu Uzunhan, Nur Aydınlı, Meliha Mine Çalışkan, Meral Özmen

Amaç: Psödotümör serebri sendromu (PTSS) tanılı çocukların demografik özellikleri, başvuru semptomları ve görüntüleme bulgularını tanımlayarak idyopatik intrakranial hipertansiyon (İİH) (primer PTSS) ile sekonder PTSS arasındaki farkların saptanması amaçlandı. Gereç ve Yöntem: Ocak 2011 ile Ocak 2016 tarihleri arasında çocuk nörolojisi polikliniğinden PTSS tanısı ile takip edilmekte olan 18 yaşından küçük çocukların medikal kayıtları ve beyin görüntüleme bulguları geriye dönük olarak değerlendirildi. Çocuklar İİH tanılı olanlar ve sekonder PTSS gelişenler olmak üzere iki grupta incelendi. Bulgular: Çalışmaya 26 çocuk dahil edildi. Birinci grup 16, 2. grup 10 hastadan oluşuyordu. İkinci gruptaki hastaların 4’ünde sinüs ven trombozu, 1’inde otoimmün tiroidit, 1’inde hipotiroidi, 1’inde Down sendromu, 1’inde hipofiz adenomu, 1’inde gebelik ilişkili PTSS saptandı. Bir hastada ise büyüme hormonu tedavisi almakta iken PTSS gelişmişti. Başvuru anındaki yaş ortalamaları, prepubertal/postpubertal hasta oranı, baş ağrısı, çift görme, görme bulanıklığı/kaybı ve bulantı/ kusma varlığı açısından gruplar arasında istatiksel açıdan anlamlı fark saptanmadı (p>0,05). Pozitif radyolojik bulgu oranı iki grup arasında istatiksel olarak farklı değildi (p>0,05). Sonuç: PTSS saptanan çocuklarda başvuru şikayetleri ve beyin görüntüleme bulguları idyopatik olanlar ile sekonder PTSS gelişenler arasında benzer bulunmuştur. 

Keywords: Çocuk, psödotümör serebri, idyopatik intrakranial hipertansiyon

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APA

Bektaş, G., Pembegül Yıldız, E., Aksu Uzunhan, T., Aydınlı, N., Çalışkan, M.M., & Özmen, M. (2017). PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS. Journal of Istanbul Faculty of Medicine, 80(4), 146-152. https://doi.org/10.18017/iuitfd.382761


AMA

Bektaş G, Pembegül Yıldız E, Aksu Uzunhan T, Aydınlı N, Çalışkan M M, Özmen M. PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS. Journal of Istanbul Faculty of Medicine. 2017;80(4):146-152. https://doi.org/10.18017/iuitfd.382761


ABNT

Bektaş, G.; Pembegül Yıldız, E.; Aksu Uzunhan, T.; Aydınlı, N.; Çalışkan, M.M.; Özmen, M. PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 80, n. 4, p. 146-152, 2017.


Chicago: Author-Date Style

Bektaş, Gonca, and Edibe Pembegül Yıldız and Tuğçe Aksu Uzunhan and Nur Aydınlı and Meliha Mine Çalışkan and Meral Özmen. 2017. “PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS.” Journal of Istanbul Faculty of Medicine 80, no. 4: 146-152. https://doi.org/10.18017/iuitfd.382761


Chicago: Humanities Style

Bektaş, Gonca, and Edibe Pembegül Yıldız and Tuğçe Aksu Uzunhan and Nur Aydınlı and Meliha Mine Çalışkan and Meral Özmen. “PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS.” Journal of Istanbul Faculty of Medicine 80, no. 4 (May. 2024): 146-152. https://doi.org/10.18017/iuitfd.382761


Harvard: Australian Style

Bektaş, G & Pembegül Yıldız, E & Aksu Uzunhan, T & Aydınlı, N & Çalışkan, MM & Özmen, M 2017, 'PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS', Journal of Istanbul Faculty of Medicine, vol. 80, no. 4, pp. 146-152, viewed 20 May. 2024, https://doi.org/10.18017/iuitfd.382761


Harvard: Author-Date Style

Bektaş, G. and Pembegül Yıldız, E. and Aksu Uzunhan, T. and Aydınlı, N. and Çalışkan, M.M. and Özmen, M. (2017) ‘PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS’, Journal of Istanbul Faculty of Medicine, 80(4), pp. 146-152. https://doi.org/10.18017/iuitfd.382761 (20 May. 2024).


MLA

Bektaş, Gonca, and Edibe Pembegül Yıldız and Tuğçe Aksu Uzunhan and Nur Aydınlı and Meliha Mine Çalışkan and Meral Özmen. “PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS.” Journal of Istanbul Faculty of Medicine, vol. 80, no. 4, 2017, pp. 146-152. [Database Container], https://doi.org/10.18017/iuitfd.382761


Vancouver

Bektaş G, Pembegül Yıldız E, Aksu Uzunhan T, Aydınlı N, Çalışkan MM, Özmen M. PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS. Journal of Istanbul Faculty of Medicine [Internet]. 20 May. 2024 [cited 20 May. 2024];80(4):146-152. Available from: https://doi.org/10.18017/iuitfd.382761 doi: 10.18017/iuitfd.382761


ISNAD

Bektaş, Gonca - Pembegül Yıldız, Edibe - Aksu Uzunhan, Tuğçe - Aydınlı, Nur - Çalışkan, MelihaMine - Özmen, Meral. “PRIMARY AND SECONDARY PSEUDOTUMOR CEREBRI SYNDROME IN CHILDHOOD: SYMPTOMS AND IMAGING FINDINGS”. Journal of Istanbul Faculty of Medicine 80/4 (May. 2024): 146-152. https://doi.org/10.18017/iuitfd.382761



TIMELINE


Submitted01.12.2017
Accepted06.12.2017
Published Online20.12.2017

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