References

• 1. Ashavaid T, Raje H, Shalia K, Shah B. Effect of gene polymorphisms on the levels of calcineurin inhibitors in Indian renal transplant recipients. Indian J Nephrol 2010;20(3):146-51. google scholar
• 2. Khakhar AK, Shahinian VB, House AA, Muirhead N, Hollomby DJ, Leckie SH, et al. The impact of allograft nephrectomy on percent panel reactive antibody and clinical outcome. Transpl Proc 2003;35(2):862-63. google scholar
• 3. Roth D, Colona J, Burke GW, Ciancio G, Esquenazi V, Miller J. Primary immunosuppression with tacrolimus and mycophenolate mofetil for renal allograft recipients. Transplantation 1998;65(2):248-52. google scholar
• 4. Staatz CE, Tett SE. Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients. Clin Pharmacokinet 2007;46(1):13-58. google scholar
• 5. Bullingham RE, Nicholls AJ, Kamm BR. Clinical pharmacokinetics of mycophenolate mofetil. Clin Pharmacokinet 1998;34(6):429-55. google scholar
• 6. Guillemette C. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics 2003;3(3):136-58. google scholar
• 7. Lin GF, Guo WC, Chen JG, Qin YO, Golka K, Xiang CQ, et al. An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. Toxicol Sci 2005;85(1):502-6. google scholar
• 8. Bernard O, Guillemette O. The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occuring variant. Drug Metab Dispos 2004;32(8):775-8. google scholar
• 9. Shaw LM, Korecka M, Venkataramanan R, Goldberg L, Bloom R, Brayman KL. Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies. Am J Transplant 2003;3(5):534-42. google scholar
• 10. Henderson DR, Friedman SB, Harris JD, Manning WB, Zoccoli MA. CEDIA, a new homogeneous immunoassay system. Clin Chem 1986;32(9):1637-41. google scholar
• 11. De Loor H, Naesens M, Verbeke K, Vanrenterghem Y, Kuypers DR. Stability of mycophenolic acid and glucuronide metabolites in human plasma and the impact of deproteinization methodology. Clinica Chim Acta 2008;389(1-2):87-92. 12. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999;55(2):713-23. google scholar
• 13. Meier-Kriesche HU, Li S, Gruessner RW, Fung JJ, Bustami RT, Barr ML, Leichtman AB. Immunosuppression: evolution in practice and trends, Am J Transplant 2006;6(5):1111-31. google scholar
• 14. Girard H, Court MH, Bernard O, Fortier LC, Villeneuve L, Hao Q, et al. Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver. Pharmacogenetics 2004;14(8):501-15. google scholar
• 15. Pou L, Brunet M, Cantarell C, Vidal E, Oppenheimer F, Monforte V, et al. Mycophenolic acid plasma concentrations: influence of comedication. Ther Drug Monit 2001;23(1):35-8. google scholar
• 16. Djebli N, Picard N, Rérolle JP, Le Meur Y, Marquet P. Influence of the UGTB27 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients. Pharmacogenet Genomics 2007;17(5):321-30. google scholar
• 17. Pazik J, Ołdak M, Lewandowski Z, Podgórska M, Sitarek E, Płoski R, et al. Uridine diphosphate glucuronosyltransferase 2B7 variant p.His268Tyr as a predictor of kidney allograft early acute rejection. Transplant Proc 2013;45(4):1516-9. google scholar
• 18. Michelon H, Konig J, Durrbach A, Quteineh l, Verstuyft C, Furlan V, et al. SLCO1B1 genetic polymorphism influences mycophenolic acid tolerance in renal transplant recipients. Pharmacogenomics 2010;11(2):1703-13. google scholar
• 19. Woillard JB, Rerolle JP, Picard N, Rousseau A, Drouet M, Munteanu E, et al. Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele. Br J Clin Pharmacol 2010;69(6):675-83. google scholar
• 20. Xie XC, Li J, Wang HY, Li HL, Liu J, Fu Q, et al. Associations of UDP-glucuronosyltransferases polymorphisms with mycophenolate mofetil pharmacokinetics in Chinese renal transplant patients. Acta Pharmacol Sin 2015;36(5):644-50. google scholar
• 21. Bernard O, Tojcic J, Joumault K, Perusse L, Guillemette C. Influence of nonsynonymous polymorphism of UGT1A8 and UGT2B7 metabolizing enzymeson the formation of phenolic and acly glucuronides of mycophenolic acid. Drug Metab Dispos 2006;34(9):1539-45. google scholar
• 22. Levesque E, Delage R, Benoit-Biancamano MO, Caron P, Bernard O, Couture F, et al. The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers. Clin Pharmacol Ther 2007;81(3):392-400. google scholar
• 23. Kagaya H, Inoue K, Miura M, Satoh S, Saito M, Tada H, et al. Influence of UGT1A8 and UGT2B7 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal tranpslant recipients. Eur J Clin Pharmacol 2007;63(3):279-88. google scholar
• 24. Yu ZC, Zhou PJ, Wang XH, Françoise B, Xu D, Zhang WX, et al. Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in Chinese adult renal transplant recipients. Acta Pharmacol Sin 2017: DOI: 10.1038/aps.2017.115. google scholar
• 25. Le Meur Y, Büchler M, Thierry A, Caillard S, Villemain F, Lavaud S, et al. Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation. Am J Transplant 2007;7(11):2496-503. google scholar

Citations