EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH  VARICEAL HEMORRHAGE

Karaali Rezan; Payza Umut; Kayalı Ahmet; Topal Firdevs; Topal Fatih

doi:https://dx.doi.org/10.26650/IUITFD.2020.0055

Research Article

DOI :10.26650/IUITFD.2020.0055 IUP :10.26650/IUITFD.2020.0055 Full Text (PDF)

EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE

Rezan Karaali, Umut Payza, Ahmet Kayalı, Firdevs Topal, Fatih Esad Topal

Objective: In this study, we investigated the effect of the QTc interval in cirrhosis patients on mortality and morbidity in esophageal variceal hemorrhages. Material and Method: It was retrospectively scanned in a single-centred design. The QTC intervals before and during the bleeding were calculated. The demographic characteristics and mortality status were recorded. Results: Bleeding was detected in 117 of the 156 patients. A total of 83% of these were male, and 17% were female. The QTc interval in these patients measured at the time of bleeding was longer than that measured before bleeding (p<0.001). The QTc interval of the patients who died due to bleeding was found to be 509.9 ms. It was calculated for males as 520.6 ms, and 487.4 ms for females. In the ROC analysis that was conducted for the QTc in terms of mortality, the sensitivity was 82.4% and specificity was 79.7% for 464.0 ms in males (AUC:0.785; 95% CI 0.724-0.825). The sensitivity was 77.8% and the specificity was 90.0% for QTc’s 454.0 ms cutoff value for females (AUC:856; 95% CI 0.812-0.862). Conclusion: The QTc interval is prolonged in the case of esophageal variceal hemorrhage in patients diagnosed with cirrhosis. A prolonged QTc interval is associated with mortality and morbidity of patients.

Keywords: Emergency department, cirrhosis, QTc interval, variceal hemorrhage

DOI :10.26650/IUITFD.2020.0055 IUP :10.26650/IUITFD.2020.0055 Full Text (PDF)

VARİS KANAMASI OLAN SİROZ HASTALARINDA QTC İNTERVALİNİN DEĞERLENDİRİLMESİ

Rezan Karaali, Umut Payza, Ahmet Kayalı, Firdevs Topal, Fatih Esad Topal

Amaç: Bu çalışmada QTc intervalinin siroz hastalarında meydana gelen özofagus varis kanamasının mortalite ve morbidite üzerindeki etkisi araştırıldı. Gereç ve Yöntem: Çalışma, retrospektif, tek merkezli yapıldı. Hastaların kanama öncesi ve kanama anındaki QTc intervalleri hesaplandı. Hastaların demografik özellikleri ve mortalite durumları kaydedildi. Bulgular: Yüz elli altı hastanın 117'sinde kanama saptandı. Bunların %83'ü erkek, %17'si kadındı. Kanama anında ölçülen QTc intervali kanama öncesi ölçülenden uzundu (p<0,001). Kanama nedeniyle ölen hastaların QTc süresi 509,9 ms olarak bulundu. Erkekler için hesaplanan QTc değeri 520,6 ms ve kadınlar için hesaplanan 487,4 ms idi. Mortalite açısından QTc için yapılan ROC analizinde, erkeklerde 464,0 ms için sensitivite %82,4 ve spesivite %79,7 olarak bulundu (AUC:0,785; 95% CI 0.724-0,825). Kadınlarda QTc’nin 454,0 ms, cutoff değeri için sensitivite %77,8 ve spesivite %90,0 olarak bulundu (AUC:856; 95% CI 0.812-0,862). Sonuç: Siroz tanısı olan hastalarda özofagus varis kanaması durumunda QTc intervali uzamaktadır. Uzamış QTc intervali hastaların mortalite ve morbiditesi ile ilişkilidir.

Keywords: Acil servis, siroz, QTc intervali, varis kanaması

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APA

Karaali, R., Payza, U., Kayalı, A., Topal, F., & Topal, F.E. (2021). EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE. Journal of Istanbul Faculty of Medicine, 84(2), 181-185. https://doi.org/10.26650/IUITFD.2020.0055

AMA

Karaali R, Payza U, Kayalı A, Topal F, Topal F E. EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE. Journal of Istanbul Faculty of Medicine. 2021;84(2):181-185. https://doi.org/10.26650/IUITFD.2020.0055

ABNT

Karaali, R.; Payza, U.; Kayalı, A.; Topal, F.; Topal, F.E. EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 84, n. 2, p. 181-185, 2021.

Chicago: Author-Date Style

Karaali, Rezan, and Umut Payza and Ahmet Kayalı and Firdevs Topal and Fatih Esad Topal. 2021. “EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE.” Journal of Istanbul Faculty of Medicine 84, no. 2: 181-185. https://doi.org/10.26650/IUITFD.2020.0055

Chicago: Humanities Style

Karaali, Rezan, and Umut Payza and Ahmet Kayalı and Firdevs Topal and Fatih Esad Topal. “EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE.” Journal of Istanbul Faculty of Medicine 84, no. 2 (May. 2024): 181-185. https://doi.org/10.26650/IUITFD.2020.0055

Harvard: Australian Style

Karaali, R & Payza, U & Kayalı, A & Topal, F & Topal, FE 2021, 'EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE', Journal of Istanbul Faculty of Medicine, vol. 84, no. 2, pp. 181-185, viewed 21 May. 2024, https://doi.org/10.26650/IUITFD.2020.0055

Harvard: Author-Date Style

Karaali, R. and Payza, U. and Kayalı, A. and Topal, F. and Topal, F.E. (2021) ‘EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE’, Journal of Istanbul Faculty of Medicine, 84(2), pp. 181-185. https://doi.org/10.26650/IUITFD.2020.0055 (21 May. 2024).

MLA

Karaali, Rezan, and Umut Payza and Ahmet Kayalı and Firdevs Topal and Fatih Esad Topal. “EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE.” Journal of Istanbul Faculty of Medicine, vol. 84, no. 2, 2021, pp. 181-185. [Database Container], https://doi.org/10.26650/IUITFD.2020.0055

Vancouver

Karaali R, Payza U, Kayalı A, Topal F, Topal FE. EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE. Journal of Istanbul Faculty of Medicine [Internet]. 21 May. 2024 [cited 21 May. 2024];84(2):181-185. Available from: https://doi.org/10.26650/IUITFD.2020.0055 doi: 10.26650/IUITFD.2020.0055

ISNAD

Karaali, Rezan - Payza, Umut - Kayalı, Ahmet - Topal, Firdevs - Topal, FatihEsad. “EVALUATION OF QTC INTERVAL IN CIRRHOSIS PATIENTS WITH VARICEAL HEMORRHAGE”. Journal of Istanbul Faculty of Medicine 84/2 (May. 2024): 181-185. https://doi.org/10.26650/IUITFD.2020.0055

Volume 84, Issue 22021, P. 181-185

TIMELINE

Submitted	10.05.2020
Accepted	05.11.2020
Published Online	01.04.2021

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