LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE  STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL

Demirkan Fatma; Karatekin Şeyma

doi:https://dx.doi.org/10.26650/IUITFD.2021.809729

Research Article

DOI :10.26650/IUITFD.2021.809729 IUP :10.26650/IUITFD.2021.809729 Full Text (PDF)

LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL

Objective: The aim of this study is to investigate the relation between anemia, vitamin deficiency, thyroid dysfunction, and the cognitive status of patients admitted to the medical board due to symptoms of cognitive retardation, a condition that is common in childhood and affects school success negatively. Materials and Methods: In this study, between January 2016- June 2018, serum vitamin B12, ferritin, hemogram and thyroid function tests of 71 pediatric patients, who were found to have had cognitive deficiencies and were admitted to the secondary level state hospital to obtain a medical committee report, were assessed retrospectively. Results: Among 71 children included in the study, 35.2% (n=25) were female and 64.8% (n=46) were male. Mean age was 11.5±2.1. Iron deficiency was detected in 9% of them. While 53.5% of them had normal vitamin B12 levels, the remaining had various degrees of vitamin B12 deficiencies. Thyroid dysfunction was not detected in any patient. There was no significant difference in vitamin B12 (p=0.2) and ferritin (p=0.6) levels in both genders. Normal intelligence score was obtained in 16 (22.5%) of all cases. Mild mental retardation was detected in 8 of the patients with vitamin B12 deficiency, borderline cognitive dysfunction was detected in 19 patients and cognitive dysfunction scores in 6 patients. While 10 of 38 patients without deficiency had normal intelligence quotient scores, 28 had at least 1 level of mental retardation. When the intelligence quotient of the patients with vitamin B12 deficiency and those with normal serum vitamin B12 were compared, no significant difference was found (p=0.13). There was no significant difference in vitamin B12 and ferritin levels when comparing patients with at least one level of mental retardation and normal intelligence scores (p=0.2; p=0.9). Conclusion: During the evaluation of the patients with cognitive retardation, nutritional vitamin-mineral deficiency and anemia status should be evaluated at the initial examination and the cognitive status of the patients should be re-evaluated after treatment.

Keywords: Cognitive dysfunction, vitamin B12, ferritin

DOI :10.26650/IUITFD.2021.809729 IUP :10.26650/IUITFD.2021.809729 Full Text (PDF)

İKİNCİ BASAMAK DEVLET HASTANESİ SAĞLIK KURULUNDA BİLİŞSEL DURUM DEĞERLENDİRMESİ YAPILAN ÇOCUKLARIN LABORATUVAR BULGULARI

Fatma Gül Demirkan, Şeyma Karatekin

Amaç: Çalışmanın amacı, çocukluk çağında sık karşılaşılan ve okul başarısını etkileyen bir durum olan bilişsel gerilik bulguları nedeniyle sağlık kuruluna başvuran hastaların anemi, vitamin eksikliği ve tiroid fonksiyon bozukluğu ile bilişsel durumları arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: Çalışmada Ocak 2016-Haziran 2018 tarihleri arasında bilişsel gerilik bulguları nedeniyle ikinci basamak devlet hastanesi sağlık kuruluna başvuran 71 çocuk hastanın serum vitamin B12, ferritin değerleri, hemogram ve tiroid fonksiyon testleri geriye dönük olarak değerlendirildi. Bulgular: Kayıtlarına ulaşılan 71 hastanın %35,2’si (n=25) kız; %64,8’i (n=46) erkekti. Yaş ortalaması 11,5±2,1’di. Hastaların %9’unda demir eksikliği tespit edildi. %53,5’inde vitamin B12 düzeyi normal bulunurken diğer yarısında çeşitli derecelerde eksiklik olduğu görüldü. Hiçbir hastada tiroid fonksiyon bozukluğu tespit edilmedi. Her iki cinsiyette de vitamin B12 (p=0,2) ve ferritin (p=0,6) düzeyleri açısından anlamlı fark olmadığı görüldü. Olguların 16 (%22,5)’sında normal zekâ puanı tespit edildi. Vitamin B12 eksikliği olan hastaların (n=33) 8’inde hafif derecede zekâ geriliği, 19 hastada sınır ve donuk zekâ, 6 hastada ise normal zekâ puanı tespit edilmişti. Eksiklik olmayan 38 hastanın 10’unda zekâ seviyesi normalken 28’inde en az bir düzeyde zekâ geriliği mevcuttu. Vitamin B12 eksikliği olan hastalar ile normal olan hastaların zekâ puanları karşılaştırıldığında anlamlı fark tespit edilmedi (p=0,13). En az bir seviyede zekâ geriliği olan ve zekâ puanı tamamen normal olan hastalar arasında karşılaştırma yapıldığında ise vitamin B12 ve ferritin seviyeleri açısından anlamlı fark bulunmadı (p=0,2; p=0,9). Sonuç: Bilişsel gerilik tanısı konmadan hastaların ilk muayenede nutrisyonel vitamin ve mineral eksikliği ile anemi durumu değerlendirilip tedavi sonrasında bilişsel durumları tekrar değerlendirilmelidir

Keywords: Bilişsel gerilik, vitamin B12, ferritin

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APA

Demirkan, F.G., & Karatekin, Ş. (2021). LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL. Journal of Istanbul Faculty of Medicine, 84(3), 396-401. https://doi.org/10.26650/IUITFD.2021.809729

AMA

Demirkan F G, Karatekin Ş. LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL. Journal of Istanbul Faculty of Medicine. 2021;84(3):396-401. https://doi.org/10.26650/IUITFD.2021.809729

ABNT

Demirkan, F.G.; Karatekin, Ş. LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 84, n. 3, p. 396-401, 2021.

Chicago: Author-Date Style

Demirkan, Fatma Gül, and Şeyma Karatekin. 2021. “LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL.” Journal of Istanbul Faculty of Medicine 84, no. 3: 396-401. https://doi.org/10.26650/IUITFD.2021.809729

Chicago: Humanities Style

Demirkan, Fatma Gül, and Şeyma Karatekin. “LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL.” Journal of Istanbul Faculty of Medicine 84, no. 3 (Nov. 2024): 396-401. https://doi.org/10.26650/IUITFD.2021.809729

Harvard: Australian Style

Demirkan, FG & Karatekin, Ş 2021, 'LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL', Journal of Istanbul Faculty of Medicine, vol. 84, no. 3, pp. 396-401, viewed 23 Nov. 2024, https://doi.org/10.26650/IUITFD.2021.809729

Harvard: Author-Date Style

Demirkan, F.G. and Karatekin, Ş. (2021) ‘LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL’, Journal of Istanbul Faculty of Medicine, 84(3), pp. 396-401. https://doi.org/10.26650/IUITFD.2021.809729 (23 Nov. 2024).

MLA

Demirkan, Fatma Gül, and Şeyma Karatekin. “LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL.” Journal of Istanbul Faculty of Medicine, vol. 84, no. 3, 2021, pp. 396-401. [Database Container], https://doi.org/10.26650/IUITFD.2021.809729

Vancouver

Demirkan FG, Karatekin Ş. LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL. Journal of Istanbul Faculty of Medicine [Internet]. 23 Nov. 2024 [cited 23 Nov. 2024];84(3):396-401. Available from: https://doi.org/10.26650/IUITFD.2021.809729 doi: 10.26650/IUITFD.2021.809729

ISNAD

Demirkan, FatmaGül - Karatekin, Şeyma. “LABORATORY FINDINGS OF CHILDREN ASSESSED IN RELATION TO COGNITIVE STATE BY THE HEALTH COMMITTEE OF A SECOND LEVEL STATE HOSPITAL”. Journal of Istanbul Faculty of Medicine 84/3 (Nov. 2024): 396-401. https://doi.org/10.26650/IUITFD.2021.809729

Volume 84, Issue 32021, P. 396-401

TIMELINE

Submitted	13.10.2020
Accepted	01.04.2021
Published Online	05.07.2021

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