Journal of Istanbul Faculty of Medicine

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Original Research


DOI :https://doi.org/10.18017/iuitfd.308491   IUP :https://doi.org/10.18017/iuitfd.308491    Full Text (PDF)

INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS

Şenol Çomoğlu, Erkan Öztürk, Necati Enver, İlker Erdinç Eroğlu, Mehmet Çelik, Beldan Polat, Meryem Nesil Keleş Türel, M. Kemal Değer

Objective: This study aimed to present the clinical and pathological features that effect the recurrence and malignancy by analysis of results of inverted papilloma surgery performed in our center.

Materials and Methods: The data of 52 patients whom underwent surgery because of inverted papilloma at Department of Otorhinolaryngology, Istanbul Faculty of Medicine between 2008 and 2015 was investigated retrospectively. Demographic datas of patients, prior surgery, origin of tumor, stage, initial symptoms, and surgical techniques were evaluated.

Results: The mean age of 52 patients whom were treated from inverted papilloma was 59.3±12.4, and age range was 32-84. 41 of 52 patients were male and 11 were female. The distribution of the patients according to Krouse Staging system was determined such as; 1 of patients was T4, 4 were T2, 41 patients were T3 and 6 were T4.

In all, nine patients were found having squamous cell carcinoma or dysplasia. It is found that the smoking did not have an effect on recurrence (p=0.289) and prior surgery (p=0.748), prior surgery history was related to multiple location (p=0.043).

The mean follow-up period was 49,5±26,6 and minimum and maximum follow-up periods were 2-96 months. The mean age recurrence time was found as 41.3 months.

Conclusion: The most important factor to prevent the recurrence of inverted papilloma is to determine the location and to excise exactly. The relation of smoking and old surgery story with the reccurence could not be proved but it is seen that multiple location was related with repeating surgery. Larger case series and controlled studies are needed to obtain clearer statistical results.

Keywords: intranasal surgery, inverted papilloma, neoplasm, paranasal sinus
DOI :https://doi.org/10.18017/iuitfd.308491   IUP :https://doi.org/10.18017/iuitfd.308491    Full Text (PDF)

İNVERTED PAPİLLOM: KAPSAMLI KLİNİK ANALİZ

Şenol Çomoğlu, Erkan Öztürk, Necati Enver, İlker Erdinç Eroğlu, Mehmet Çelik, Beldan Polat, Meryem Nesil Keleş Türel, M. Kemal Değer

Amaç: Çalışmanın amacı kliniğimizde uygulanan sinonazal inverted papillom cerrahisinin sonuçlarını analiz ederek rekürrens ve malignite üzerine etki eden klinik ve patolojik faktörleri ortaya koymaktır.

Gereç ve yöntem: 2008-2015 yılları arasında İstanbul Tıp Fakültesi KBB Kliniğinde inverted papillom nedeniyle cerrahi tedavi uygulanan 52 hastanın sonuçları retrospektif olarak incelendi. Hastaların demografik verileri, eski cerrahi, kaynaklandığı anatomik yer, evre, başvuru semptomları ve cerrahi teknik bilgisi değerlendirildi.

Bulgular: İnverted papillom tanısı ile tedavi edilen 52 hastanın yaş ortalaması 59.3±12.4 olup yaş aralığı 32-84’tür. 52 hastanın 41’i erkek, 11’i kadındı. Hastaların Krouse evreleme sistemine göre 1’i T1, 4’ü T2, 41’i T3, 6’sı ise T4 olarak dağıldığı saptanmıştır.

 Toplamda 9 hastada yassı hücreli kanser veya displazi olduğu saptanmıştır. Sigaranın nüks (p=0.289) ve geçirilmiş eski cerrahi (p=0.748) üzerine etkisi olmadığı, eski cerrahi öyküsünün multiple yerleşimle (p=0.043) anlamlı olarak ilişkili olduğu saptanmıştır.

Ortalama takip süresi 49.5±26.6 iken; minimum-maksimum takip süresi 2-96 ay idi. Ortalama nüks süresi 41.3 ay olarak bulundu.

Sonuç: İnverted papillomun nüksünü önlemede en önemli faktör yerleşim yerinin tespit edilmesi ve tam olarak eksize edilmesidir. Sigara ve eski cerrahi öyküsünün rekürrensle ilişkisi gösterilememekle birlikte, multiple yerleşimin tekrarlayan cerrahi ile ilişkili olduğu görülmektedir. Daha net istatistiksel sonuçların elde edilebilmesi için daha geniş vaka serileri ve kontrollü çalışmalara ihtiyaç vardır.

Keywords: intranazal cerrahi, inverted papillom, neoplazm, paranazal sinüs

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APA

Çomoğlu, Ş., Öztürk, E., Enver, N., Eroğlu, İ.E., Çelik, M., Polat, B., Keleş Türel, M.N., & Değer, M.K. (2016). INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS. Journal of Istanbul Faculty of Medicine, 79(4), 157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491


AMA

Çomoğlu Ş, Öztürk E, Enver N, Eroğlu İ E, Çelik M, Polat B, Keleş Türel M N, Değer M K. INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS. Journal of Istanbul Faculty of Medicine. 2016;79(4):157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491


ABNT

Çomoğlu, Ş.; Öztürk, E.; Enver, N.; Eroğlu, İ.E.; Çelik, M.; Polat, B.; Keleş Türel, M.N.; Değer, M.K. INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 79, n. 4, p. 157-162, 2016.


Chicago: Author-Date Style

Çomoğlu, Şenol, and Erkan Öztürk and Necati Enver and İlker Erdinç Eroğlu and Mehmet Çelik and Beldan Polat and Meryem Nesil Keleş Türel and M. Kemal Değer. 2016. “INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS.” Journal of Istanbul Faculty of Medicine 79, no. 4: 157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491


Chicago: Humanities Style

Çomoğlu, Şenol, and Erkan Öztürk and Necati Enver and İlker Erdinç Eroğlu and Mehmet Çelik and Beldan Polat and Meryem Nesil Keleş Türel and M. Kemal Değer. “INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS.” Journal of Istanbul Faculty of Medicine 79, no. 4 (May. 2025): 157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491


Harvard: Australian Style

Çomoğlu, Ş & Öztürk, E & Enver, N & Eroğlu, İE & Çelik, M & Polat, B & Keleş Türel, MN & Değer, MK 2016, 'INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS', Journal of Istanbul Faculty of Medicine, vol. 79, no. 4, pp. 157-162, viewed 16 May. 2025, https://doi.org/https://doi.org/10.18017/iuitfd.308491


Harvard: Author-Date Style

Çomoğlu, Ş. and Öztürk, E. and Enver, N. and Eroğlu, İ.E. and Çelik, M. and Polat, B. and Keleş Türel, M.N. and Değer, M.K. (2016) ‘INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS’, Journal of Istanbul Faculty of Medicine, 79(4), pp. 157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491 (16 May. 2025).


MLA

Çomoğlu, Şenol, and Erkan Öztürk and Necati Enver and İlker Erdinç Eroğlu and Mehmet Çelik and Beldan Polat and Meryem Nesil Keleş Türel and M. Kemal Değer. “INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS.” Journal of Istanbul Faculty of Medicine, vol. 79, no. 4, 2016, pp. 157-162. [Database Container], https://doi.org/https://doi.org/10.18017/iuitfd.308491


Vancouver

Çomoğlu Ş, Öztürk E, Enver N, Eroğlu İE, Çelik M, Polat B, Keleş Türel MN, Değer MK. INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS. Journal of Istanbul Faculty of Medicine [Internet]. 16 May. 2025 [cited 16 May. 2025];79(4):157-162. Available from: https://doi.org/https://doi.org/10.18017/iuitfd.308491 doi: https://doi.org/10.18017/iuitfd.308491


ISNAD

Çomoğlu, Şenol - Öztürk, Erkan - Enver, Necati - Eroğlu, İlkerErdinç - Çelik, Mehmet - Polat, Beldan - Keleş Türel, MeryemNesil - Değer, M.Kemal. “INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS”. Journal of Istanbul Faculty of Medicine 79/4 (May. 2025): 157-162. https://doi.org/https://doi.org/10.18017/iuitfd.308491



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